Robots Are Not All the Same: Young Adults' Expectations, Attitudes, and Mental Attribution to Two Humanoid Social Robots

The human physical resemblance of humanoid social robots (HRSs) has proven to be particularly effective in interactions with humans in different contexts. In particular, two main factors affect the quality of human-robot interaction, the physical appearance and the behaviors performed by the robot. In this study, we examined the psychological effect of two HRSs, NAO and Pepper. Although some studies have shown that these two robots are very similar in terms of the human likeness, other evidence has shown some differences in their design affecting different psychological elements of the human partner. The present study aims to analyze the variability of the attributions of mental states (AMS), expectations of robotic development and negative attitudes as a function of the physical appearance of two HRSs after observing a real interaction with a human (an experimenter). For this purpose, two groups of young adults were recruited, one for the NAO

Can You Activate Me? From Robots to Human Brain

L'efficacia dei robot sociali \ue8 stata ampiamente riconosciuta in diversi contesti della vita quotidiana degli umani, ma ancora poco si sa sulle aree cerebrali attivate osservando o interagendo con un robot. La ricerca che combina neuroscienze, scienze cognitive e robotica pu\uf2 fornire nuove intuizioni sia sul funzionamento del nostro cervello che sull'implementazione dei robot. Studi comportamentali sui robot sociali hanno dimostrato che la percezione sociale dei robot \ue8 influenzata da almeno due fattori: aspetto fisico e comportamento (Marchetti et al., 2018). Come possono le neuroscienze spiegare tali risultati? Ad oggi sono stati condotti studi attraverso l'utilizzo di tecniche sia EEG che fMRI per indagare le aree cerebrali coinvolte nell'interazione uomo-robot. Questi studi hanno affrontato principalmente le attivazioni cerebrali in risposta a paradigmi che coinvolgono o la performance di un'azione o la carica di una componente emotiva.The effectiveness of social robots has been widely recognized in different contexts of humans\u2019 daily life, but still little is known about the brain areas activated by observing or interacting with a robot. Research combining neuroscience, cognitive science and robotics can provide new insights into both the functioning of our brain and the implementation of robots. Behavioural studies on social robots have shown that the social perception of robots is influenced by at least two factors: physical appearance and behavior (Marchetti et al., 2018). How can neuroscience explain such findings? To date, studies have been conducted through the use of both EEG and fMRI techniques to investigate the brain areas involved in human-robot interaction. These studies have mainly addressed brain activations in response to paradigms involving either action performance or charged of an emotional component

What is the role of the placebo effect for pain relief in neurorehabilitation? Clinical implications from the Italian consensus conference on pain in neurorehabilitation

Background: It is increasingly acknowledged that the outcomes of medical treatments are influenced by the context of the clinical encounter through the mechanisms of the placebo effect. The phenomenon of placebo analgesia might be exploited to maximize the efficacy of neurorehabilitation treatments. Since its intensity varies across neurological disorders, the Italian Consensus Conference on Pain in Neurorehabilitation (ICCP) summarized the studies on this field to provide guidance on its use. Methods: A review of the existing reviews and meta-analyses was performed to assess the magnitude of the placebo effect in disorders that may undergo neurorehabilitation treatment. The search was performed on Pubmed using placebo, pain, and the names of neurological disorders as keywords. Methodological quality was assessed using a pre-existing checklist. Data about the magnitude of the placebo effect were extracted from the included reviews and were commented in a narrative form. Results: 11 articles were included in this review. Placebo treatments showed weak effects in central neuropathic pain (pain reduction from 0.44 to 0.66 on a 0-10 scale) and moderate effects in postherpetic neuralgia (1.16), in diabetic peripheral neuropathy (1.45), and in pain associated to HIV (1.82). Moderate effects were also found on pain due to fibromyalgia and migraine; only weak short-term effects were found in complex regional pain syndrome. Confounding variables might have influenced these results. Clinical implications: These estimates should be interpreted with caution, but underscore that the placebo effect can be exploited in neurorehabilitation programs. It is not necessary to conceal its use from the patient. Knowledge of placebo mechanisms can be used to shape the doctor-patient relationship, to reduce the use of analgesic drugs and to train the patient to become an active agent of the therapy

Robots Are Not All the Same: Young Adults' Expectations, Attitudes, and Mental Attribution to Two Humanoid Social Robots

The human physical resemblance of humanoid social robots (HRSs) has proven to be particularly effective in interactions with humans in different contexts. In particular, two main factors affect the quality of human-robot interaction, the physical appearance and the behaviors performed by the robot. In this study, we examined the psychological effect of two HRSs, NAO and Pepper. Although some studies have shown that these two robots are very similar in terms of the human likeness, other evidence has shown some differences in their design affecting different psychological elements of the human partner. The present study aims to analyze the variability of the attributions of mental states (AMS), expectations of robotic development and negative attitudes as a function of the physical appearance of two HRSs after observing a real interaction with a human (an experimenter). For this purpose, two groups of young adults were recruited, one for the NAO (N\u2009=\u2009100, M\u2009=\u200920.22) and the other for the Pepper (N\u2009=\u200974, M\u2009=\u200921.76). The results showed that both the observation of interaction and the type of robot affect the AMS, with a greater AMS to Pepper robot compared to NAO. People's expectations, instead, are influenced by the interaction and are independent of the type of robot. Finally, negative attitudes are independent of both the interaction and the type of robot. The study showed that also subtle differences in the physical appearance of HSRs have significant effects on how humans perceived robots

A phase II trial of weekly nab-paclitaxel for progressive and symptomatic desmoid tumors.

Desmoid fibromatosis (DF) are mesenchymal neoplasms, with potential aggressive course and relevant clinical impact. New systemic therapy modalities are needed in this symptomatic/progressive population. In this multicenter, phase II trial (NCT03275818), patients with symptomatic/progressing DF received three cycles of weekly nab-paclitaxel. Brief pain inventory short form (BPI-SF) was collected at baseline and in every visit. MRI was performed every 3 months. Primary composite endpoint was RECIST 1.1 overall response rate (ORR) and/or clinical response (improvement ≥ 2 points in BPI-SF). If 40% of patients achieved clinical/radiological response, further investigation would be warranted. Toxicity, progression-free survival (PFS), pattern of response and its correlation with clinical best response and BPI, variation of physical function, and analgesic consumption were secondary endpoints. The translational research reported was not a pre-specified secondary outcome. Forty eligible patients started therapy, being 35 radiologically and clinically evaluable. The study achieved its primary endpoint, as 7(20%) patients obtained RECIST partial response, whereas 31(89%) experienced pain reduction of ≥2 points in BPI-SF worst pain. Therapy was well tolerated. With a median follow-up of 30(14-44) months, median 12 and 24-months PFS rates were 91%(CI 95%, 82-100) and 84%(CI 95%, 71-97). For clinical progression, 12 and 24-months PFS rates were 85% (CI 95%, 73-97) and 74% (CI 95%, 58-90) respectively. Short course of nab-paclitaxel is active, safe and achieves quick and durable responses in progressing/symptomatic DF patients

sj-png-1-tam-10.1177_17588359231220611 – Supplemental material for Delays in diagnosis and surgery of sarcoma patients during the COVID-19 outbreak in Spain

Supplemental material, sj-png-1-tam-10.1177_17588359231220611 for Delays in diagnosis and surgery of sarcoma patients during the COVID-19 outbreak in Spain by Jaime Carrillo-García, Serena Lacerenza, Nadia Hindi, Irene Carrasco García, Gloria Marquina, Juana María Cano Cano, Javier Martínez Trufero, Alberto Rafael Sevillano Tripero, Tania Luis García, Manuel Jorge Cuesta Rioboo, David S. Moura, Marta Renshaw, Jose L. Mondaza-Hernández, Davide Di Lernia, Antonio Gutierrez and Javier Martin-Broto in Therapeutic Advances in Medical Oncology</p

sj-png-2-tam-10.1177_17588359231220611 – Supplemental material for Delays in diagnosis and surgery of sarcoma patients during the COVID-19 outbreak in Spain

Supplemental material, sj-png-2-tam-10.1177_17588359231220611 for Delays in diagnosis and surgery of sarcoma patients during the COVID-19 outbreak in Spain by Jaime Carrillo-García, Serena Lacerenza, Nadia Hindi, Irene Carrasco García, Gloria Marquina, Juana María Cano Cano, Javier Martínez Trufero, Alberto Rafael Sevillano Tripero, Tania Luis García, Manuel Jorge Cuesta Rioboo, David S. Moura, Marta Renshaw, Jose L. Mondaza-Hernández, Davide Di Lernia, Antonio Gutierrez and Javier Martin-Broto in Therapeutic Advances in Medical Oncology</p

Changes in surgicaL behaviOrs dUring the CoviD-19 pandemic. The SICE CLOUD19 Study

BACKGROUND: The spread of the SARS-CoV2 virus, which causes COVID-19 disease, profoundly impacted the surgical community. Recommendations have been published to manage patients needing surgery during the COVID-19 pandemic. This survey, under the aegis of the Italian Society of Endoscopic Surgery, aims to analyze how Italian surgeons have changed their practice during the pandemic.METHODS: The authors designed an online survey that was circulated for completion to the Italian departments of general surgery registered in the Italian Ministry of Health database in December 2020. Questions were divided into three sections: hospital organization, screening policies, and safety profile of the surgical operation. The investigation periods were divided into the Italian pandemic phases I (March-May 2020), II (June-September 2020), and III (October-December 2020).RESULTS: Of 447 invited departments, 226 answered the survey. Most hospitals were treating both COVID-19-positive and -negative patients. The reduction in effective beds dedicated to surgical activity was significant, affecting 59% of the responding units. 12.4% of the respondents in phase I, 2.6% in phase II, and 7.7% in phase III reported that their surgical unit had been closed. 51.4%, 23.5%, and 47.8% of the respondents had at least one colleague reassigned to non-surgical COVID-19 activities during the three phases. There has been a reduction in elective (>200 procedures: 2.1%, 20.6% and 9.9% in the three phases, respectively) and emergency (<20 procedures: 43.3%, 27.1%, 36.5% in the three phases, respectively) surgical activity. The use of laparoscopy also had a setback in phase I (25.8% performed less than 20% of elective procedures through laparoscopy). 60.6% of the respondents used a smoke evacuation device during laparoscopy in phase I, 61.6% in phase II, and 64.2% in phase III. Almost all responders (82.8% vs. 93.2% vs. 92.7%) in each analyzed period did not modify or reduce the use of high-energy devices.CONCLUSION: This survey offers three faithful snapshots of how the surgical community has reacted to the COVID-19 pandemic during its three phases. The significant reduction in surgical activity indicates that better health policies and more evidence-based guidelines are needed to make up for lost time and surgery not performed during the pandemic