3,536 research outputs found
Intrapreneurial self-capital training: a case study of an Italian university student
This chapter presents a case study which describes the application of the Intrapreneurial Self-Capital Training with a final-year postgraduate female biology student, Erica. The chapter presents an overview of theory that is relevant to the world of work and the conceptual dimensions of intrapreneurial self capital (ISC). Training for ISC aims to assist young people to identify their personal strengths in terms of intrapreneurship and career adaptability. A qualitative instrument, the Life Adaptability Qualitative Assessment (LAQuA) was administered before and after the training to detect meaningful changes in the participant’s narratives about career adaptability and enhanced reflexivity. The LAQuA coding system revealed enhancements to the participant’s awareness about her personal intrapreneurial resources and career adaptability. The relevance of ISC to employability and career services in education contexts is discussed along with recommendations for research into ISC training
Pneumococcal surface protein A of invasive Streptococcus pneumoniae isolates from Colombian children.
Pneumococcal surface protein A (PspA) elicits protection in mice against fatal bacteremia and sepsis caused by genetically diverse pneumococci and protects against carriage and lung infection. We determined the PspA families of invasive isolates of Streptococcus pneumoniae recovered from Colombian children <5 years of age. That 97.5% of Colombian isolates belong to PspA families 1 and 2 supports the hypothesis that a human PspA vaccine covering a few PspA families could be broadly effective
Prescription of benzodiazepines in a public general hospital in theprovince of Mendoza: problematic consumption?
Aún administradas regularmente a niveles terapéuticos, las BZD poseen un potencial de dependencia mayor que otros fármacos de acción ansiolÃtica y se ha reportado tolerancia farmacológica cuando la prescripción es por un tiempo mayor a cuatro semanas, asà como la aparición del sÃndrome de abstinencia en el 30% de los pacientes después de un tratamiento de ocho semanas de duración
On the asymptotic behaviour of solutions to the fractional porous medium equation with variable density
We are concerned with the long time behaviour of solutions to the fractional
porous medium equation with a variable spatial density. We prove that if the
density decays slowly at infinity, then the solution approaches the
Barenblatt-type solution of a proper singular fractional problem. If, on the
contrary, the density decays rapidly at infinity, we show that the minimal
solution multiplied by a suitable power of the time variable converges to the
minimal solution of a certain fractional sublinear elliptic equation.Comment: To appear in DCDS-
Comparing thigh muscle cross-sectional area and squat strength among national class Olympic weightlifters, power lifters, and bodybuilders
Few studies have compared anthropometric characteristics among national class athletes from different resistance training disciplines, such as Olympic Weightlifting (OL), Power Lifting (PL), and Bodybuilding (BB). Objective: The purpose of the current study was to determine if significant differences exist in the relationship between thigh muscle cross-sectional area and back squat strength among national class athletes from the sports of OL, PL, and BB. Methods: Fifteen national class athletes were assessed for back squat strength, mid-thigh circumference, and mid-thigh skinfold from which total thigh cross-sectional was estimated. A series of One-Way ANOVAs and Pearson Product Moment Correlations were used to compare groups and assess the relationship between variables. Results: The OL (200.18 + 25.16kg) and PL (205.45 + 17.28kg) groups were significantly stronger than the BB (160 + 16.80 kg; p \u3c 0.05) group. However, mid-thigh skinfold thickness (p = 0.36), mid-thigh circumference (p = 0.87), and estimated thigh cross-sectional area (p = 0.34) were not significantly different between groups. Thigh muscle cross-sectional area was weakly correlated to back squat strength in the OL (r = .42) and PL (r = .12) groups, but moderately correlated in the BB (r = .70) group. Conclusion: Thigh cross-sectional area was of relatively minor importance in determining back squat strength for the OL and PL groups, despite these groups being significantly stronger than the BB group. Specific training protocols will elicit different outcomes with regard to muscular hypertrophy that may or may not contribute to a functional increase in back squat strength
Effects of macroscopic polarization in III-V nitride multi-quantum-wells
Huge built-in electric fields have been predicted to exist in wurtzite III-V
nitrides thin films and multilayers. Such fields originate from heterointerface
discontinuities of the macroscopic bulk polarization of the nitrides. Here we
discuss the background theory, the role of spontaneous polarization in this
context, and the practical implications of built-in polarization fields in
nitride nanostructures. To support our arguments, we present detailed
self-consistent tight-binding simulations of typical nitride QW structures in
which polarization effects are dominant.Comment: 11 pages, 9 figures, uses revtex/epsf. submitted to PR
Discovery of the Eu decay
We report on the first compelling observation of decay of Eu
to the ground state of Pm. The measurement was performed using a 6.15 g
LiEu(BO) crystal operated as a scintillating bolometer. The Q-value
and half-life measured are: Q = 1948.9 keV, and
T y . The
half-life prediction of nuclear theory using the Coulomb and proximity
potential model are in good agreement with this experimental result
Low pH immobilizes and kills human leukocytes and prevents transmission of cell-associated HIV in a mouse model
BACKGROUND: Both cell-associated and cell-free HIV virions are present in semen and cervical secretions of HIV-infected individuals. Thus, topical microbicides may need to inactivate both cell-associated and cell-free HIV to prevent sexual transmission of HIV/AIDS. To determine if the mild acidity of the healthy vagina and acid buffering microbicides would prevent transmission by HIV-infected leukocytes, we measured the effect of pH on leukocyte motility, viability and intracellular pH and tested the ability of an acidic buffering microbicide (BufferGel(®)) to prevent the transmission of cell-associated HIV in a HuPBL-SCID mouse model. METHODS: Human lymphocyte, monocyte, and macrophage motilities were measured as a function of time and pH using various acidifying agents. Lymphocyte and macrophage motilities were measured using video microscopy. Monocyte motility was measured using video microscopy and chemotactic chambers. Peripheral blood mononuclear cell (PBMC) viability and intracellular pH were determined as a function of time and pH using fluorescent dyes. HuPBL-SCID mice were pretreated with BufferGel, saline, or a control gel and challenged with HIV-1-infected human PBMCs. RESULTS: Progressive motility was completely abolished in all cell types between pH 5.5 and 6.0. Concomitantly, at and below pH 5.5, the intracellular pH of PBMCs dropped precipitously to match the extracellular medium and did not recover. After acidification with hydrochloric acid to pH 4.5 for 60 min, although completely immotile, 58% of PBMCs excluded ethidium homodimer-1 (dead-cell dye). In contrast, when acidified to this pH with BufferGel, a microbicide designed to maintain vaginal acidity in the presence of semen, only 4% excluded dye at 10 min and none excluded dye after 30 min. BufferGel significantly reduced transmission of HIV-1 in HuPBL-SCID mice (1 of 12 infected) compared to saline (12 of 12 infected) and a control gel (5 of 7 infected). CONCLUSION: These results suggest that physiologic or microbicide-induced acid immobilization and killing of infected white blood cells may be effective in preventing sexual transmission of cell-associated HIV
Keep looking ahead? Re-direction of visual fixation does not always occur during an unpredictable obstacle avoidance task
Visual information about the environment, especially fixation of key objects such as obstacles, is critical for safe locomotion. However, in unpredictable situations where an obstacle suddenly appears it is not known whether central vision of the obstacle and/or landing area is required or if peripheral vision is sufficient. We examined whether there is a re-direction of visual fixation from an object fixated ahead to a suddenly appearing obstacle during treadmill walking. Furthermore, we investigated the temporal relationship between the onset of muscle activity to avoid the obstacle and saccadic eye and head movements to shift fixation. Eight females (mean SD; age = 24.8 2.3 years) participated in this experiment. There were two visual conditions: a central vision condition where participants fixated on two obstacles attached to a bridge on the treadmill and a peripheral vision condition where participants fixated an object two steps ahead. There were two obstacle release conditions: only an obstacle in front of the left foot was released or an obstacle in front of either foot could be released. Only trials when the obstacle was released in front of the left foot were analyzed such that the difference in the two obstacle conditions was whether there was a choice of which foot to step over the obstacle. Obstacles were released randomly in one of three phases during the step cycle corresponding to available response times between 219 and 462 ms. We monitored eye and head movements along with muscle activity and spatial foot parameters. Performance on the task was not different between vision conditions. The results indicated that saccades are rarely made (< 18% of trials) and, when present, are initiated ∼ 350 ms after muscle activity for limb elevation, often accompanied by a downward head movement, and always directed to the landing area. Therefore, peripheral vision of a suddenly appearing obstacle in the travel path is sufficient for successful obstacle avoidance during locomotion: visual fixation is generally not re-directed to either the obstacle or landing area
Proposal for a Datta-Das transistor in the quantum Hall regime
We propose a resonant spin-field-effect transistor for chiral spin-resolved
edge states in the integer quantum Hall effect with Rashba spin-orbit
interaction. It employs a periodic array of voltage-controlled top gates that
locally modulate the Rashba spin-orbit interaction. Strong resonant spin-field
effect is achieved when the array periodicity matches the inverse of the
wave-vector difference of the two chiral states involved. Well-known techniques
of separately contacting the edge states make it possible to selectively
populate and read out the edge states, allowing full spin readout. The resonant
nature of the spin-field effect and the adiabatic character of the edge states
guarantee a high degree of robustness with respect to disorder. Our device
represents the quantum Hall version of the all-electrical Datta-Das spin-field
effect transistor.Comment: 6 pages, 5 figure
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