Non-suicidal self-injury: clinical presentation, assessment and management

Non-suicidal self-injury is a common behaviour in adolescents and young adults, and may be associated with mental health disorders, risk of suicidal behaviour (ideation and attempts), and a need for clinical services. Nurses, in particular those working in emergency departments and mental health settings, have a crucial role in the assessment, treatment and care of individuals who have self-injured. It is essential for nurses to assess an individual’s risk of more serious harm or accidental death, regardless of intent. It is also important to understand the variations in non-suicidal self-injurious behaviour in terms of its presentation, features and functions, to provide appropriate person-centred care. Nurses should assist individuals in identifying the triggers or cues for their behaviour, exploring treatment options, and monitoring their behaviour and risk in the long term. This article describes the profile of people who self-injure, and the issues related to assessment and management of such patients presenting in emergency departments. A description of who self-injures and why, and how people self-injure; developmental aspects of these behaviours, including short and long-term outcomes; and the available treatments is presented

Postgraduate Research Students’ and their Supervisors’ Attitudes towards Supervision

There is a need for research exploring postgraduate research students’ expectations from research supervisors, the characteristics of effective student-supervisor relationships, and the opinions of students and supervisors about research supervision. We also need instruments to explore the student-supervisor relationship. The present study investigated postgraduate research students’ and research supervisors’ views about postgraduate research supervision and the student supervisor relationship. It also reports on factor analysis conducted to identify the underlying dimensions in their views about postgraduate research supervision and the student supervisor relationship. Such information can be used to develop strategies to promote student-supervisor relationships and enhance the student experience. Data were collected using an online questionnaire with 30 Likert-scale statements from 131 postgraduate research students and 77 supervisors. Following exploratory factor analysis, a three factor model consisting of leaderhip, knowledge, and support was extracted. Results indicate that students and supervisors agree about the attributes of effective supervision. Both supervisors and students consider that a supervisor should have an interest in the student’s research. The supervisor must provide timely and constructive feedback and should help the student to manage time effectively. Students and supervisors believe a supervisor should help the students where limitations and learning needs are identified. Students believe supervisors must encourage students to work independently and use opportunities to present their work

Hypercholesterolemia and apolipoprotein B expression: Regulation by selenium status

BACKGROUND: Apolipoprotein B (apoB) contains ligand-binding domain for the binding of LDL to LDL-R site, which enables the removal of LDL from circulation. Our recent data showed that selenium (Se) is involved in the lipid metabolism. The present study was aimed to understand the effect of Se deficiency (0.02 ppm) and selenium supplementation (1 ppm) on apoB expression in liver during hypercholesterolemia in male Sprague Dawley rats. Animals were fed with control and high cholesterol diet (2%) for 1 and 2 months. ApoB levels by ELISA and protein expression by western blot was done. Hepatic LDL receptor (LDL-R) activity (in vivo) and mRNA expression by RT-PCR was monitored. RESULTS: In selenium deficiency and on high cholesterol diet (HCD) feeding apoB levels increased and LDL-R expression decreased significantly after 2 months. On 1 ppm selenium supplementation apoB expression significantly decreased and LDL-R expression increased after 2 months. But after one month of treatment there was no significant change observed in apoB and LDL-R expression. CONCLUSION: So the present study demonstrates that Se deficiency leads to up regulation of apoB expression during experimental hypercholesterolemia. Selenium supplementation upto 1 ppm leads to downregulation of apoB expression. Further, this study will highlight the nutritional value of Se supplementation in lipid metabolism

Validation of Visual Estimation of Portion Size Consumed as a Method for Estimating Food Intake by Young Indian Children

In this observational study, estimation of food intake was evaluated using recording of portion size consumed, instead of post-weighing, as a method. In total, 930 feeding episodes were observed among 128 children aged 12–24 months in which actual intake was available by pre- and post-weighing. For each offering and feeding episode, portion size consumed was recorded by an independent nutritionist—as none, less than half, half or more, and all. Using the pre-weighed offering, available intake was estimated by multiplying portion sizes by the estimated weight. The estimated mean intake was 510.4 kilojoules compared to actual intake of 510.7 kilojoules by weighing. Similar results were found with nestum (52.0 vs 56.2 g), bread (3.8 vs 3.7 g), puffed rice (1.7 vs 1.9 g), banana (31.3 vs 24.4 g), and milk (41.6 vs 44.2 mL). Recording portion size consumed and estimating food intake from that provides a good alternative to the time-consuming and often culturally-unacceptable method of post-weighing food each time after a feeding episode

Identifying signs of intimate partner violence.

Intimate partner violence is a major public health and social problem that affects people in every community, culture and country. Nurses can play a very important role in identifying victims who present to healthcare settings domestic abuse-related health issues. Evidence suggests that the majority of women who present to emergency departments have experienced domestic abuse at some point in their life, however, only 5% are identified by healthcare professionals. To be able to effectively identify and respond to victims, emergency nurses need to understand domestic abuse and its associated complexities. This article provides an overview of the issue, including the different types of abuse, prevalence, causes and effects on health. It also explores emergency nurses’ roles in identifying and managing various situations they may encounter at wor

Zinc Deficiency: Descriptive Epidemiology and Morbidity among Preschool Children in Peri-urban Population in Delhi, India

Community-based data relating to factors influencing zinc deficiency among preschool children in India are inadequate. Data of a large, double-blinded, randomized, controlled zinc-supplementation trial were used for assessing the descriptive epidemiology of zinc deficiency among children aged 6–35 months (n=940). In total, 609 children were followed up for 120 days for information on morbidity. Of these children, 116 from the control group belonging to the upper and the lower 25th quartile of plasma zinc status at baseline were selected for assessing the association of zinc deficiency with prospective morbidity. At baseline, demographic, socioeconomic and dietary information was collected, and anthropometric measurements and levels of plasma zinc were assessed. At baseline, 73.3% of the children were zinc-deficient (plasma zinc <70 µg/dL), of which 33.8% had levels of plasma zinc below 60 µg/dL. A significantly higher risk of morbidity was prevalent among the subjects with lower plasma zinc compared to those with higher levels of plasma zinc

How have EU’s trade agreements impacted consumers?

Over the past two decades, the European Commission has negotiated a number of Free Trade Agreements (FTAs) which contain both traditional elements of bilateral tariff reductions, as well as additional liberalisation measures like non-tariff barriers. According to economic theory, FTAs lower trade barriers on imported goods, leading to consumer welfare gains from increase in product variety, better quality products and lower prices for existing products. We estimate the variety, quality and price effects of EU FTAs, drawing on recent developments in the quality literature and using detailed import price and expenditure data. On average, trade agreements the EU has entered into over the past two decades increased the quality of UK imports from its FTA partners by 26 per cent and lowered the quality-adjusted price of imports by 19 per cent. We find that consumer prices fell by 0.5 per cent for UK consumers as a result of FTAs with trade partners that are not members of the European Community. Price reductions for UK consumers are greater than those for EU12 consumers, whose prices fell by 0.3 per cent from non-EC FTAs. Using the set of non-EC FTA estimates to predict the effects of future FTAs, we find a projected decline in consumer prices for UK consumers of 0.4 per cent from an FTA with the United States (TTIP) and 0.2 per cent an FTA with Japan (EPA). For EU12 consumers, the TTIP and EPA are predicted to reduce consumer prices by 0.3 per cent and 0.1 per cent

A Bifactorial Solution to the Psychopathy Checklist: Screening Version in a Sample of Civil Psychiatric Patients

Background There is considerable debate about the underlying factor structure of the Psychopathy Checklist: Screening Version (PCL: SV). An established view is that it reflects a unitary construct underpinned by two correlated factors. More recent research has, however, undermined this conceptualisation. Aims Our aim was to compare 10 competing models of the PCL: SV in a sample of civil psychiatric patients. Method Ten distinct factor models were specified and tested using conventional confirmatory factor analytic techniques, along with confirmatory bifactor modelling. Results A bifactor model, including two general factors (interpersonal–affective and antisocial–lifestyle), and four subordinate factors (interpersonal, affective, antisocial and lifestyle) provided the best fit to the data. The reliability of the conceptualisation was supported through the use of composite reliability, and the differential relationships exhibited between the general factors and measures of personality, impulsivity and mental health. Conclusions Our findings provide further weight to taking the two general psychopathy factors into account when interpreting the PCL: SV for clinical purposes