G.M.C. Balayogi fish landing jetty, Savithri Nagar, Yanam, U.T. of Pondicherry

The Pondicherry Government took initiative to con- struct a fish landing jetty for the benefit of Savitrinagar and Bhairavapalem fishers named G.M.C. Balayogi fish landing jetty.At an average about 140 Trawlers utilize this facility for berthing and sale of fish

Synergistic effects of squalene and polyunsaturated fatty acid concentrate on lipid peroxidation and antioxidant status in isoprenaline-induced myocardial infarction in rats

We have studied the synergistic effects of squalene and polyunsaturated fatty acids (PUFA concentrate) on isoprenaline-induced infarction in rats with respect to changes in the levels of plasma diagnostic marker enzymes and myocardial antioxidant defense system. Intraperitoneal injection of isoprenaline caused a significant elevation in the levels of diagnostic marker enzymes; alanineaminotranferase (ALT), aspartate aminotransferase (AST), lactate dehydrogenase (LDH) and creatine phosphokinase (CPK) in plasma of experimental rats. There was a significant rise in the level of lipidperoxidation with concomitant decline in the level of reduced glutathione (GSH) and in the activities of glutathione-dependent antioxidant enzymes; glutathione peroxidase (GPX) and glutathione-Stransferase (GST), and antiperoxidative enzymes; superoxide dismutase (SOD) and catalase (CAT) in heart tissue. Combined supplementation of squalene and PUFA concentrate significantly prevented the isoprenaline-induced elevations in the levels of diagnostic marker enzymes in plasma of experimental groups of rats. A tendency to counteract the isoprenaline induced lipid peroxidation was also noticed. Their combined administration maintained the level of GSH and the activities of glutathione-dependent antioxidant enzymes and antiperoxidative enzymes at near normalcy. The results of the present study indicated that the combined administration of squalene and PUFA concentrate exerted significantly better cardio-protection against isoprenaline-intoxication as compared to that of per secondsupplementation

Interactions between labile carbon, temperature and land use regulate carbon dioxide and methane production in tropical peat

Tropical peatlands are a significant carbon store and contribute to global carbon dioxide (CO2) and methane (CH4) emissions. Tropical peatlands are threatened by both land use and climate change, including the alteration of regional precipitation patterns, and the 3–4 °C predicted warming by 2100. Plant communities in tropical peatlands can regulate greenhouse gas (GHG) fluxes through labile carbon inputs, but the extent to which these inputs regulate the temperature response of CO2 and CH4 production in tropical peat remains unclear. We conducted an anoxic incubation experiment using three peat types of contrasting botanical origin to assess how carbon addition affects the temperature response (Q10) of CO2 and CH4 production. Peats from forested peatlands in Panama and Malaysia, and a converted oil palm and pineapple intercropping system in Malaysia, differed significantly in redox potential, total carbon and carbon: nitrogen ratio. The production of CO2 and CH4 varied significantly among peat types and increased with increasing temperature, with Q10s for both gases of 1.4. Carbon addition further increased gas fluxes, but did not influence the Q10 for CO2 or CH4 production or significantly affect the Q10 of either gas. These findings demonstrate that the production of CO2 and CH4 in tropical peat is sensitive to warming and varies among peat types, but that the effect of root inputs in altering Q10 appears to be limited. © 2019, The Author(s)

Evaluation of soluble ST2 as a novel cardiovascular biomarker in patients with acute myocardial infarction

Background: Soluble ST-2 has considerable prognostic value and is used as an aid for risk stratification in identifying patients who are at high risk of cardiovascular disease. The main objective of the study was to analyze the level of soluble ST-2 biomarker in patients with acute myocardial infarction and chronic stable angina patients and secondly to evaluate the cardiovascular outcomes after 30 days.Methods: A total of 71 patients were enrolled into the study, patients were divided into two groups of which 50 patients were in test group (AMI patients) and the remaining 21 patients were in the control group (chronic stable angina). Then, 5ml of blood was collected from the patients and plasma soluble ST-2 was estimated from the sample using ELISA technique. Patients were then followed up to 30 days to ascertain the development of major adverse cardiovascular outcomes.Results: The median concentration of soluble ST-2 in test group was found to be 213.46pg/ml and in control group was found to be 124.53 pg/ml. Soluble ST-2 correlated significantly with left ventricular ejection fraction (LVEF) between the two groups (P value=0.01). Measurement of soluble ST-2 early after MI assists in the prediction of adverse cardiovascular events. In this study, soluble ST-2 was found to be higher in patients with acute myocardial infarction and also in patients with poor ejection fraction.Conclusions: Soluble ST-2 is a novel cardiovascular biomarker that is elevated in patients with acute myocardial infarction

Investigation on Effect of Material Hardness in High Speed CNC End Milling Process

This research paper analyzes the effects of material properties on surface roughness, material removal rate, and tool wear on high speed CNC end milling process with various ferrous and nonferrous materials. The challenge of material specific decision on the process parameters of spindle speed, feed rate, depth of cut, coolant flow rate, cutting tool material, and type of coating for the cutting tool for required quality and quantity of production is addressed. Generally, decision made by the operator on floor is based on suggested values of the tool manufacturer or by trial and error method. This paper describes effect of various parameters on the surface roughness characteristics of the precision machining part. The prediction method suggested is based on various experimental analysis of parameters in different compositions of input conditions which would benefit the industry on standardization of high speed CNC end milling processes. The results show a basis for selection of parameters to get better results of surface roughness values as predicted by the case study results

Balanced Schnyder woods for planar triangulations: an experimental study with applications to graph drawing and graph separators

In this work we consider balanced Schnyder woods for planar graphs, which are Schnyder woods where the number of incoming edges of each color at each vertex is balanced as much as possible. We provide a simple linear-time heuristic leading to obtain well balanced Schnyder woods in practice. As test applications we consider two important algorithmic problems: the computation of Schnyder drawings and of small cycle separators. While not being able to provide theoretical guarantees, our experimental results (on a wide collection of planar graphs) suggest that the use of balanced Schnyder woods leads to an improvement of the quality of the layout of Schnyder drawings, and provides an efficient tool for computing short and balanced cycle separators.Comment: Appears in the Proceedings of the 27th International Symposium on Graph Drawing and Network Visualization (GD 2019

Morphing Schnyder drawings of planar triangulations

We consider the problem of morphing between two planar drawings of the same triangulated graph, maintaining straight-line planarity. A paper in SODA 2013 gave a morph that consists of $O(n^2)$ steps where each step is a linear morph that moves each of the $n$ vertices in a straight line at uniform speed. However, their method imitates edge contractions so the grid size of the intermediate drawings is not bounded and the morphs are not good for visualization purposes. Using Schnyder embeddings, we are able to morph in $O(n^2)$ linear morphing steps and improve the grid size to $O(n)\times O(n)$ for a significant class of drawings of triangulations, namely the class of weighted Schnyder drawings. The morphs are visually attractive. Our method involves implementing the basic "flip" operations of Schnyder woods as linear morphs.Comment: 23 pages, 8 figure

On the Area Requirements of Planar Greedy Drawings of Triconnected Planar Graphs

In this paper we study the area requirements of planar greedy drawings of triconnected planar graphs. Cao, Strelzoff, and Sun exhibited a family $\cal H$ of subdivisions of triconnected plane graphs and claimed that every planar greedy drawing of the graphs in $\mathcal H$ respecting the prescribed plane embedding requires exponential area. However, we show that every $n$-vertex graph in $\cal H$ actually has a planar greedy drawing respecting the prescribed plane embedding on an $O(n)\times O(n)$ grid. This reopens the question whether triconnected planar graphs admit planar greedy drawings on a polynomial-size grid. Further, we provide evidence for a positive answer to the above question by proving that every $n$-vertex Halin graph admits a planar greedy drawing on an $O(n)\times O(n)$ grid. Both such results are obtained by actually constructing drawings that are convex and angle-monotone. Finally, we consider $\alpha$-Schnyder drawings, which are angle-monotone and hence greedy if $\alpha\leq 30^\circ$, and show that there exist planar triangulations for which every $\alpha$-Schnyder drawing with a fixed $\alpha<60^\circ$ requires exponential area for any resolution rule

The Cytokinin Complex Associated With Rhodococcus fascians: Which Compounds Are Critical for Virulence?

Virulent strains of Rhodococcus fascians cause a range of disease symptoms, many of which can be mimicked by application of cytokinin. Both virulent and avirulent strains produce a complex of cytokinins, most of which can be derived from tRNA degradation. To test the three current hypotheses regarding the involvement of cytokinins as virulence determinants, we used PCR to detect specific genes, previously associated with a linear virulence plasmid, including two methyl transferase genes (mt1 and mt2) and fas4 (dimethyl transferase), of multiple strains of R. fascians. We inoculated Pisum sativum (pea) seeds with virulent and avirulent strains of R. fascians, monitored the plants over time and compared these to mock-inoculated controls. We used RT-qPCR to monitor the expression of mt1, mt2, and fas4 in inoculated tissues and LC-MS/MS to obtain a comprehensive picture of the cytokinin complement of inoculated cotyledons, roots and shoots over time. The presence and expression of mt1 and mt2 was associated with those strains of R. fascians classed as virulent, and not those classed as avirulent. Expression of mt1, mt2, and fas4 peaked at 9 days post-inoculation (dpi) in cotyledons and at 15 dpi in shoots and roots developed from seeds inoculated with virulent strain 602. Pea plants inoculated with virulent and avirulent strains of R. fascians both contained cytokinins likely to have been derived from tRNA turnover including the 2-methylthio cytokinins and cis-zeatin-derivatives. Along with the isopentenyladenine-type cytokinins, the levels of these compounds did not correlate with virulence. Only the novel 1- and 2-methylated isopentenyladenine cytokinins were uniquely associated with infection by the virulent strains and are, therefore, the likely causative factors of the disease symptoms

Phenylalanine hydroxylase contributes to serotonin synthesis in mice

This is the final version. Available from the Federation of American Society of Experimental Biology via the DOI in this record.Serotonin is an important signaling molecule in the periphery and in the brain. The hydroxylation of tryptophan is the first and rate-limiting step of its synthesis. In most vertebrates, two enzymes have been described to catalyze this step, tryptophan hydroxylase (TPH) 1 and 2, with expression localized to peripheral and neuronal cells, respectively. However, animals lacking both TPH isoforms still exhibit about 10% of normal serotonin levels in the blood demanding an additional source of the monoamine. In this study, we provide evidence by the gain and loss of function approaches in in vitro and in vivo systems, including stable-isotope tracing in mice, that phenylalanine hydroxylase (PAH) is a third TPH in mammals. PAH contributes to serotonin levels in the blood, and may be important as a local source of serotonin in organs in which no other TPHs are expressed, such as liver and kidney.Saint Petersburg State University (SPbU)Bundesministerium für Bildung und Forschung (BMBF)Deutsches Zentrum für Herz-Kreislaufforschung (DZHK)Volkswagen Foundation (VolkswagenStiftung