Morphometry and kinematics of landslides inferred from precise DTMs in West Belgium

International audienceThe Flemish Ardennes (W Belgium) are known to be affected by deep-seated landslides. The assessment of the landslide reactivation hazard requires understanding the driving processes and delimiting precisely not only the landslide boundaries but especially that of their most active parts. Precise 3D models of 13 landslides were produced by digital stereophotogrammetry using aerial photographs of different dates. Dealing with photographs at the scale 1:25000 or larger, we obtained for each model an accuracy better than 0.5m. As a first result, the main size parameters of the landslides (width, length, depth, volume, ...) are easily computed. Moreover, the obtained DTMs may be subtracted from each other in order to determine the apparent vertical displacement of each pixel during the interval of time considered. Provided that more than 2 epochs are documented, such DTMs not only supply precise information about distribution and style of the landslide activity but may also point to temporal variations in this activity. The subtraction of DTMs allows us to give an estimation of the volume of the "uplifted" and "collapsed" terrains between two epochs

Towards a Reproducible Pan-European Soil Erosion Risk Assessment - RUSLE

Soil is a valuable, non-renewable natural resource that offers a multitude of ecosystems goods and services. Given the increasing threat of soil erosion in Europe and the implications this has on future food security and water quality, it is important that land managers and decision makers are provided with accurate and appropriate information on the areas more prone to erosion phenomena. The present study shows an attempt to locate, at regional scale, the most sensitive areas and to highlight any changes of soil erosion trends with climate change. The choice of the input datasets is crucial as they have to offer the most homogeneous and complete covering at the pan-European level and to allow the produced information to be harmonized and easily validated. The model is based on available datasets (HWSD, SGDBE, SRTM, CLC and E-OBS) and The Revised Universal Soil Loss Equation (RUSLE) is used because of its flexibility and least data demanding. A significant effort has been made to select the better simplified equations to be used when a strict application of the RUSLE model was not possible. In particular for the computation of the Rainfall Erosivity factor a validation based on measured precipitation time series (having a temporal resolution of 10-15 minutes) has been implemented to be easily reproducible. The validation computational framework is available as free software. Designing the computational modeling architecture with the aim to ease as much as possible the future reuse of the model in analyzing climate change scenarios has also been a challenging goal of the research

Corrigendum to "Modelling soil erosion at European scale: towards harmonization and reproducibility" published in Nat. Hazards Earth Syst. Sci.,15, 225–245, 2015

No abstract available

Facial expressions depicting compassionate and critical emotions: the development and validation of a new emotional face stimulus set

Attachment with altruistic others requires the ability to appropriately process affiliative and kind facial cues. Yet there is no stimulus set available to investigate such processes. Here, we developed a stimulus set depicting compassionate and critical facial expressions, and validated its effectiveness using well-established visual-probe methodology. In Study 1, 62 participants rated photographs of actors displaying compassionate/kind and critical faces on strength of emotion type. This produced a new stimulus set based on N = 31 actors, whose facial expressions were reliably distinguished as compassionate, critical and neutral. In Study 2, 70 participants completed a visual-probe task measuring attentional orientation to critical and compassionate/kind faces. This revealed that participants lower in self-criticism demonstrated enhanced attention to compassionate/kind faces whereas those higher in self-criticism showed no bias. To sum, the new stimulus set produced interpretable findings using visual-probe methodology and is the first to include higher order, complex positive affect displays

The Nitric Oxide Pathway Provides Innate Antiviral Protection in Conjunction with the Type I Interferon Pathway in Fibroblasts

The innate host response to virus infection is largely dominated by the production of type I interferon and interferon stimulated genes. In particular, fibroblasts respond robustly to viral infection and to recognition of viral signatures such as dsRNA with the rapid production of type I interferon; subsequently, fibroblasts are a key cell type in antiviral protection. We recently found, however, that primary fibroblasts deficient for the production of interferon, interferon stimulated genes, and other cytokines and chemokines mount a robust antiviral response against both DNA and RNA viruses following stimulation with dsRNA. Nitric oxide is a chemical compound with pleiotropic functions; its production by phagocytes in response to interferon-γ is associated with antimicrobial activity. Here we show that in response to dsRNA, nitric oxide is rapidly produced in primary fibroblasts. In the presence of an intact interferon system, nitric oxide plays a minor but significant role in antiviral protection. However, in the absence of an interferon system, nitric oxide is critical for the protection against DNA viruses. In primary fibroblasts, NF-κB and interferon regulatory factor 1 participate in the induction of inducible nitric oxide synthase expression, which subsequently produces nitric oxide. As large DNA viruses encode multiple and diverse immune modulators to disable the interferon system, it appears that the nitric oxide pathway serves as a secondary strategy to protect the host against viral infection in key cell types, such as fibroblasts, that largely rely on the type I interferon system for antiviral protection

Short Day–Mediated Cessation of Growth Requires the Downregulation of AINTEGUMENTALIKE1 Transcription Factor in Hybrid Aspen

Day length is a key environmental cue regulating the timing of major developmental transitions in plants. For example, in perennial plants such as the long-lived trees of the boreal forest, exposure to short days (SD) leads to the termination of meristem activity and bud set (referred to as growth cessation). The mechanism underlying SD–mediated induction of growth cessation is poorly understood. Here we show that the AIL1-AIL4 (AINTEGUMENTALIKE) transcription factors of the AP2 family are the downstream targets of the SD signal in the regulation of growth cessation response in hybrid aspen trees. AIL1 is expressed in the shoot apical meristem and leaf primordia, and exposure to SD signal downregulates AIL1 expression. Downregulation of AIL gene expression by SDs is altered in transgenic hybrid aspen plants that are defective in SD perception and/or response, e.g. PHYA or FT overexpressors. Importantly, SD–mediated regulation of growth cessation response is also affected by overexpression or downregulation of AIL gene expression. AIL1 protein can interact with the promoter of the key cell cycle genes, e.g. CYCD3.2, and downregulation of the expression of D-type cyclins after SD treatment is prevented by AIL1 overexpression. These data reveal that execution of SD–mediated growth cessation response requires the downregulation of AIL gene expression. Thus, while early acting components like PHYA and the CO/FT regulon are conserved in day-length regulation of flowering time and growth cessation between annual and perennial plants, signaling pathways downstream of SD perception diverge, with AIL transcription factors being novel targets of the CO/FT regulon connecting the perception of SD signal to the regulation of meristem activity

BMJ Open

INTRODUCTION: Guidelines concerning the follow-up of subjects occupationally exposed to lung carcinogens, published in France in 2015, recommended the setting up of a trial of low-dose chest CT lung cancer screening in subjects at high risk of lung cancer. OBJECTIVE: To evaluate the organisation of low-dose chest CT lung cancer screening in subjects occupationally exposed to lung carcinogens and at high risk of lung cancer. METHODS AND ANALYSIS: This trial will be conducted in eight French departments by six specialised reference centres (SRCs) in occupational health. In view of the exploratory nature of this trial, it is proposed to test initially the feasibility and acceptability over the first 2 years in only two SRCs then in four other SRCs to evaluate the organisation. The target population is current or former smokers with more than 30 pack-years (who have quit smoking for less than 15 years), currently or previously exposed to International Agency for Research on Cancer group 1 lung carcinogens, and between the ages of 55 and 74 years. The trial will be conducted in the following steps: (1) identification of subjects by a screening invitation letter; (2) evaluation of occupational exposure to lung carcinogens; (3) evaluation of the lung cancer risk level and verification of eligibility; (4) screening procedure: annual chest CT scans performed by specialised centres and (5) follow-up of CT scan abnormalities. ETHICS AND DISSEMINATION: This protocol study has been approved by the French Committee for the Protection of Persons. The results from this study will be submitted to peer-reviewed journals and reported at suitable national and international meetings. TRIAL REGISTRATION NUMBER: NCT03562052; Pre-results