1,598 research outputs found
Faster algorithms for 1-mappability of a sequence
In the k-mappability problem, we are given a string x of length n and
integers m and k, and we are asked to count, for each length-m factor y of x,
the number of other factors of length m of x that are at Hamming distance at
most k from y. We focus here on the version of the problem where k = 1. The
fastest known algorithm for k = 1 requires time O(mn log n/ log log n) and
space O(n). We present two algorithms that require worst-case time O(mn) and
O(n log^2 n), respectively, and space O(n), thus greatly improving the state of
the art. Moreover, we present an algorithm that requires average-case time and
space O(n) for integer alphabets if m = {\Omega}(log n/ log {\sigma}), where
{\sigma} is the alphabet size
Possible surface plasmon polariton excitation under femtosecond laser irradiation of silicon
The mechanisms of ripple formation on silicon surface by femtosecond laser
pulses are investigated. We demonstrate the transient evolution of the density
of the excited free-carriers. As a result, the experimental conditions required
for the excitation of surface plasmon polaritons are revealed. The periods of
the resulting structures are then investigated as a function of laser
parameters, such as the angle of incidence, laser fluence, and polarization.
The obtained dependencies provide a way of better control over the properties
of the periodic structures induced by femtosecond laser on the surface of a
semiconductor material.Comment: 11 pages, 8 figures, accepted for publication in Journal of Applied
Physic
P11-20. HIV-1 gp41-specific mucosal IgAs from highly exposed but IgG seronegative women block HIV-1 epithelial transcytosis and neutralize CD4+ cell infection
A new tool based on faecal stanols can distinguish specific mammalian species in modern and past environments
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Neutron Resonance Parameters and Covariance Matrix of 239Pu
In order to obtain the resonance parameters in a single energy range and the corresponding covariance matrix, a reevaluation of 239Pu was performed with the code SAMMY. The most recent experimental data were analyzed or reanalyzed in the energy range thermal to 2.5 keV. The normalization of the fission cross section data was reconsidered by taking into account the most recent measurements of Weston et al. and Wagemans et al. A full resonance parameter covariance matrix was generated. The method used to obtain realistic uncertainties on the average cross section calculated by SAMMY or other processing codes was examined
A new tool based on faecal stanols can distinguish specific mammalian species in modern and past environments
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Integral data analysis for resonance parameters determination
Neutron time-of-flight experiments have long been used to determine resonance parameters. Those resonance parameters have then been used in calculations of integral quantities such as Maxwellian averages or resonance integrals, and results of those calculations in turn have been used as a criterion for acceptability of the resonance analysis. However, the calculations were inadequate because covariances on the parameter values were not included in the calculations. In this report an effort to correct for that deficiency is documented: (1) the R-matrix analysis code SAMMY has been modified to include integral quantities of importance, (2) directly within the resonance parameter analysis, and (3) to determine the best fit to both differential (microscopic) and integral (macroscopic) data simultaneously. This modification was implemented because it is expected to have an impact on the intermediate-energy range that is important for criticality safety applications
Akkermansia muciniphila and its role in regulating host functions
Akkermansia muciniphila is an intestinal bacterium that was isolated a decade ago from a human fecal sample. Its specialization in mucin degradation makes it a key organism at the mucosal interface between the lumen and host cells. Although it was isolated quite recently, it has rapidly raised significant interest as A. muciniphila is the only cultivated intestinal representative of the Verrucomicrobia, one of the few phyla in the human gut that can be easily detected in phylogenetic and metagenome analyses. There has also been a growing interest in A. muciniphila, due to its association with health in animals and humans. Notably, reduced levels of A. muciniphila have been observed in patients with inflammatory bowel diseases (mainly ulcerative colitis) and metabolic disorders, which suggests it may have potential anti-inflammatory properties. The aims of this review are to summarize the existing data on the intestinal distribution of A. muciniphila in health and disease, to provide insight into its ecology and its role in founding microbial networks at the mucosal interface, as well as to discuss recent research on its role in regulating host functions that are disturbed in various diseases, with a specific focus on metabolic disorders in both animals and humans. (C) 2016 Elsevier Ltd. All rights reserved.Peer reviewe
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Merger of Nuclear Data with Criticality Safety Calculations
In this paper we report on current activities related to the merger of differential/integral data (especially in the resolved-resonance region) with nuclear criticality safety computations. Techniques are outlined for closer coupling of many processes � measurement, data reduction, differential-data analysis, integral-data analysis, generating multigroup cross sections, data-testing, criticality computations � which in the past have been treated independently
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