8 research outputs found
Review of invasive meningococcal disease during the last 40 years in Turkey
- Author
- Publication venue
- 'Informa UK Limited'
- Publication date
- Field of study
Surface modification of Fe2O3 and MgO nanoparticles with agrowastes for the treatment of chlorosis in Glycine max
- Author
- A Mahmoud
- AS Prasad
- C MartĂn-FernĂĄndez
- CST AraĂșjo
- DI Njoku
- DR Kavya
- E Tronc
- FN Sayed
- FT Leila Sadeghi
- H Marschner
- JA OâRourke
- JA Wang
- JJ Lucena
- K Rajendran
- K Ramanujam
- KJ Ahn
- M Fazlzadeh
- M Soleymani
- M Vercelli
- M Wang
- N Matinise
- NG Vannerberg
- NU Prakash
- P Rajiv
- P Sathishkumar
- PVV Prasad
- R Irshad
- R Liu
- R Mariselvam
- S Bombin
- S Demirci
- S He
- S Lopez-Rayo
- S Venkateswarlu
- T Mosmann
- T Shahwan
- V Demir
- V Smuleac
- X Ma
- Y Lu
- Y Wang
- Y Yuan
- Z ZekoviÄ
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Biosensors Based on Nanomaterials: Transducers and Modified Surfaces for Diagnostics
- Author
- A Ebrahimi
- A Escosura-Muñiz de la
- A MartĂn-Barreiro
- A Nazem
- A Salahvarzi
- AP Malalasekera
- AS Bhakta
- B SepĂșlveda
- Bruce Alberts
- BTT Nguyen
- C Janeway
- CS Pundir
- E Hutter
- E Suprun
- EB Bahadır
- EL Ru
- GARY Suaifan
- H Ilkhani
- HJ Lee
- HV Demir
- I Bhatnagar
- J Soleymani
- K Brince Paul
- K Sefah
- K Takemura
- KP Singh
- L Mohammed
- L Tian
- M Azimzadeh
- M Cahay
- M Daneshpour
- M Darestani-Farahani
- M Shamsipur
- M Yousefi
- MR Romero
- MR Romero
- MR Romero
- MS Cheng
- MY Yoon
- MZA Rahim
- N Azizah
- N Formisano
- N Radha Shanmugam
- NU Khan
- P Chandra
- P Chandra
- PR Aranda
- R Pallela
- S Chung
- S Mojtaba
- S Xiong
- T Jiao
- T Zhou
- TNT Dao
- W Wu
- XT Zheng
- Y Zhang
- YS Borghei
- Z Faridli
- Z Yazdani
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- 01/01/2020
- Field of study
The use of nanoparticles has opened a new era in the development of nanobiosensors capable of achieving analytical responses that compete with the most powerful instrumental techniques. Nanobiosensors are devices that allow analytical determinations through a specific action event between an analyte ofinterest and a bio-recognition molecule. These recognition molecules as enzymes,antibodies, nucleic acids, and aptamers are studied in detail in this chapter. The role of nanomaterials in biosensors is described in a separate section since they play a central role, allowing the understanding of their physicochemical properties such as quantum confinement, surface plasmon resonance, magnetic properties, and the effect of area increase. In addition, a brief review is provided about some basic concepts for the integration of the sensor components and their function in sensing systems found in the literature. Subsequently, a classification is proposed to summarize its fundamental characteristics, mechanism of operation, analytical characteristics, advantages, and disadvantages. Then, the main nanobiosensor types found in the literature are detailed, and specific explanations are given, e.g., those based on the determination of electrical, piezoelectric, colorimetric, fluorescent, and chemiluminescent properties. Likewise, the functioning of recently developed nanobiosensors is discussed, such as those based on local (SERS). Also, the applications of nanobiosensors in different fields of biomedicine and their fundamental importance to advance in the diagnosis of multiple pathologies as cancer are detailed. Finally, we discuss the state of the art and the future perspectives of scientific development.Fil: Romero, Marcelo Ricardo. Universidad Nacional de CĂłrdoba. Instituto de InvestigaciĂłn y Desarrollo en IngenierĂa de Procesos y QuĂmica Aplicada. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas. Centro CientĂfico TecnolĂłgico Conicet - CĂłrdoba. Instituto de InvestigaciĂłn y Desarrollo en IngenierĂa de Procesos y QuĂmica Aplicada; ArgentinaFil: Picchio, MatĂas Luis. Universidad Nacional de CĂłrdoba; Argentina. Consejo Nacional de Investigaciones CientĂficas y TĂ©cnicas; Argentin
Prevalence of Childhood Affective disorders in Turkey: An epidemiological study.
- Author
- Acikel B
- Akdemir D
- Aksu H
- Aktas H
- Aktepe E
- Alaca R
- Alic BG
- Almbaidheen M
- Altun H
- Ardic UA
- Ari FP
- Arman AR
- Aslan C
- Atabay E
- Ay MG
- Aydemir H
- Ayik B
- Ayranci G
- Babadagi Z
- Basgul S
- Bayar H
- Bayhan PC
- Bayram O
- Bektas ND
- Berberoglu KK
- Bilac O
- Bilgic A
- Bostan R
- Bozkurt OH
- Cakan Y
- Cakir ED
- Canli MA
- Cansiz MA
- Celik GG
- Ceri V
- Ceylan C
- Coskun M
- Coskun N
- Coskun S
- Demir I
- Demir N
- Demir NU
- Demirci E
- Demirdogen EY
- Demirkaya SK
- Dinc G
- Dogan B
- Donder F
- Donmez YE
- Dursun OB
- Durukan I
- Efe A
- Eray S
- Erbilgin S
- Ercan ES
- Erden S
- Ersoy EG
- Eseroglu T
- Fidan T
- Firat SK
- Fis NP
- Gencoglan S
- Gok EE
- Gokcen C
- Goksoy SC
- Gokten ES
- Gorker I
- Gormez V
- Guler G
- Gules Z
- Gunay G
- Gundogdu OY
- Gunes A
- Gunes S
- Gurkan CK
- Guven G
- Herguner S
- Hesapcioglu ST
- Horozcu H
- Irmak A
- Irmak MY
- Isik U
- Kahraman O
- Kalayci BM
- Kandemir H
- Karaaslan U
- Karacetin G
- Karadag M
- Karaman D
- Kilic BG
- Kilic HT
- Kilicaslan F
- Kilincaslan A
- Kinay D
- Kinik MF
- Koc EB
- Kocael O
- Mazlum B
- Memik NC
- Mutlu RK
- Mutluer T
- Nalbant K
- Nasiroglu S
- Okumus N
- Ozbek F
- Ozcan OO
- Ozdemir DF
- Ozdemir FA
- Ozdemir H
- Ozgur BG
- Ozkan S
- Ozmen S
- Oztop D
- Ozturk M
- Ozyurt EY
- Polat B
- Polat H
- Sahin N
- San Z
- Sapmaz SY
- Sekmen E
- Sertcelik M
- Sevgen FH
- Sevince O
- Shamkhalova U
- Simsek NE
- Sinir H
- Suleyman F
- Suren S
- Tahiroglu AY
- Tanir YaĆar
- Tasdelen BI
- Taskin B
- Tekden M
- Temtek S
- Topal M
- Topal Z
- Toros F
- Tufan AE
- Tural U
- Turk T
- Ucar F
- Ucar HN
- Ugur C
- Unal F
- Uneri OS
- Uran P
- Uygun D
- Uysal T
- Uzun N
- Vatansever Z
- Vural P
- Yazgili NG
- Yazici IP
- Yazici KU
- Yildirim V
- Yildiz DM
- Yildiz N
- Yilmaz S
- Yilmaz SS
- Yuce M
- Yuksel T
- Yulaf Y
- Publication venue
- 'Elsevier BV'
- Publication date
- 03/03/2021
- Field of study
Effect of financial management practices on the development of small-to-medium size forest enterprises: insight from Pakistan
- Author
- A Azudin
- A Chakraborty
- A Genus
- A Hussain
- A Raheman
- AASG Syed
- AB Bouazza
- AR Bilal
- AR DeThomas
- B Abuzayed
- B Humphries
- B Hussain
- C Robson
- D Yazdanfar
- E Bell
- E Harash
- E Harash
- EF Brigham
- EF Brigham
- F Farhoomand
- F Maraschi
- F Modigliani
- F Olawale
- G Uwonda
- GD Bruton
- GG Meredith
- H Karadag
- H Lyngstadaas
- H Tran
- HP Dong
- I Jindrichovska
- IA Khan
- J Andersén
- J BelĂĄs
- J Gupta
- JA Wolff
- JO Okpara
- JR deAlmeida
- K Mole
- K Padachi
- KM Nguyen
- KN Palmer
- LJ Prather
- M Afeef
- M Anwar
- M Deloof
- M Gabrielsson
- M La Rocca
- M Nebhwani
- M Shaban
- M Zada
- MA Pais
- MNL Sindani
- N Kapitsinis
- N Khan
- N Maseko
- NI Kureshi
- NU Khan
- OS Badini
- P Hardi
- PJ GarcĂa-Teruel
- R Bardy
- R Buckland
- R Demir
- R Kozak
- R Soldofsky
- RE Carpenter
- RG Okafor
- RGP Mcmahon
- S Adomako
- S Baños-Caballero
- S Baños-Caballero
- S Chao
- S Claessens
- S Fraser
- S Kaya
- S Muneer
- S Suriyankietkaew
- SC Myers
- SC Myers
- T Abanis
- T Mazzarol
- TO Fagbemi
- V Tauringana
- YO Adam
- Z Mdasha
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Bone Grafts and Bone Graft Substitutes in Periodontal Therapy
- Author
- A Aral
- A Ashman
- A Ashman
- A Blay
- A Borghetti
- A Horvath
- A Kasaj
- A Kasaj
- A Kasaj
- A Kasaj
- A Magistri
- A Neamat
- A Palmieri
- A Palmieri
- A Palti
- A Piattelli
- A Piattelli
- A Piattelli
- A Scabbia
- A Schulz
- A Sculean
- A Sculean
- A Sculean
- A Sculean
- A Sculean
- A Sculean
- A Sculean
- A Sculean
- A Sculean
- A Sculean
- A Sculean
- A Shirmohammadi
- A Skoglund
- A Sogal
- A Stavropoulos
- A Stavropoulos
- A Stavropoulos
- A Stavropoulos
- A Stavropoulos
- A Sugawara
- AA Ignatius
- AB Setya
- AD Elkins
- AF Rivault
- AG Haris
- AH Reddi
- AJ Ambard
- AJ Snyder
- AK Schlegel
- AR Curtis
- AS AlGhamdi
- AS AlGhamdi
- B Aybar
- B Demir
- B Demir
- B Frei
- B Heinz
- B JĂłnsson
- B Klongnoi
- B Kuru
- B Oguntebi
- B Wenz
- B Wildemann
- BD Boyan
- BD Boyan
- BJ Jang
- BL Eppley
- BR Constantz
- BS Gurinsky
- BS Lee
- BS Lee
- BT Duval
- C Arcuri
- C Demers
- C Hayashi
- C Kasperk
- C Knabe
- C Putter De
- C Schopper
- C-K Kim
- CA Shapoff
- CC Chen
- CD Shaffer
- CE Markopoulou
- CE Misch
- CE Misch
- CE Papadopoulos
- CH Beckham
- CH HĂ€mmerle
- CH Lohmann
- CJ Couri
- CK Kim
- CL Meadows
- CL Peters
- CM Serre
- Committee on Research Science and Therapy of the American Academy of Periodontology
- CR Anderegg
- CR Diem
- CR Richardson
- CS Kim
- CY Lee
- D Anson
- D Anson
- D Benke
- D Holtzclaw
- D Tadic
- D Velasquez-Plata
- D Yu
- DA Mott
- DD Bosshardt
- DJ Zaner
- DL Cochran
- DP Callan
- DP Sarment
- DS Metsger
- E Damien
- E Kontonasaki
- E Munukka
- E Robinson
- E Rosenberg
- E Schepers
- E Schepers
- E Tezulas
- E Tezulas
- E Venezia
- EB Kenney
- EB Kenney
- EB Nery
- EB Nery
- EF Burguera
- EJ Blom
- EJ Schepers
- EP Benqué
- ER Kirsh
- ES Rosenberg
- ES Tadjoedin
- ET Altiere
- ET Scheyer
- F Bergmann
- F Carinci
- F Döri
- F Graziani
- F Louise
- F Mora
- F Schwarz
- F Schwarz
- F Schwarz
- F Schwarz
- F Schwarz
- F Tamimi
- FA Carranza Jr
- FM Chen
- FX Huber
- FX Huber
- G Bowers
- G Cardaropoli
- G Chiriac
- G Guillemin
- G Juodzbalys
- G Leung
- G Orsini
- G Polimeni
- G Polimeni
- G Zucchelli
- GC Keles
- GD Brown
- GG Zafiropoulos
- GH Evans
- GI Drury
- GM Bowers
- GM Bowers
- GM Bowers
- GM Bowers
- H Browaeys
- H Bystedt
- H Bystedt
- H DevelioÄlu
- H Li
- H Oonishi
- H Shi
- H Yli-Urpo
- H Yuan
- H Yuan
- H Yuan
- HC Lim
- HF Nasr
- HG Moghadam
- HH Ritchie
- HH Xu
- HH Xu
- HH Xu
- HK Ridgway
- HL Wang
- HR Kwon
- HR Stanley
- HR Stanley
- HV Precheur
- I Allan
- I Allan
- I Bokan
- I Sato
- I Vouros
- ID Xynos
- ID Xynos
- IG Needleman
- IO Smith
- J Czuryszkiewicz-Cyrana
- J Francis
- J Handschel
- J Mellonig
- J Noetzel
- J Sakata
- J Wilson
- J Wilson
- JA Bowen
- JB Quattlebaum
- JB Rajesh
- JC Wohlfahrt
- JC Wohlfahrt
- JC Wohlfahrt
- JD Barnett
- JD Kassolis
- JE Jacobs
- JF Hönig
- JH Villaça
- JJ Chris Arts
- JJ Sanders
- JJ Simonpietri-C
- JL Ricci
- JL Saffar
- JM Rummelhart
- JM Stein
- JQ Feng
- JR Strub
- JR Wagner
- Jr WG Long De
- JS Gross
- JS Park
- JS Sottosanti
- JS Sottosanti
- JS Zamet
- JT Mellonig
- JT Mellonig
- JT Mellonig
- JT Mellonig
- JT Mellonig
- JW Lamb 3rd
- JX Lu
- K Fujikawa
- K Hashimoto
- K Okuda
- K Shi
- K Yagihashi
- KA Al Ruhaimi
- KB Calongne
- KG Murphy
- KM Kimble
- KN Leknes
- KP Reddy
- KS TenHuisen
- KT Koo
- KY Lin
- L Comuzzi
- L Guida
- L Holmberg
- L Laurell
- L Masters
- L Trombelli
- L Trombelli
- L Trombelli
- L Trombelli
- L Trombelli
- LH Hutchens Jr
- LL Hench
- LL Hench
- LT Lindfors
- M Bohner
- M Bohner
- M Camelo
- M Camelo
- M Camelo
- M Christgau
- M Espanol
- M Esposito
- M Esposito
- M Figueiredo
- M Hallman
- M Hallman
- M Hashimoto-Uoshima
- M Ihoki
- M Jarcho
- M Jarcho
- M Kamitakahara
- M Nevins
- M Nevins
- M Nevins
- M Ohgaki
- M Orsini
- M Orsini
- M Otsuka
- M Paolantonio
- M Paolantonio
- M Paolantonio
- M Piattelli
- M Piemontese
- M Rafter
- M Thorwarth
- M Thorwarth
- M Tonetti
- M Tonetti
- M Zehnder
- MA Reynolds
- MA Reynolds
- MAW Merkx
- MB HĂŒrzeler
- MC Fagan
- MD Pietruska
- ME Aichelmann-Reidy
- ME Aichelmann-Reidy
- ME Machado
- MF Gomes
- MJ Danesh-Meyer
- MJ Hoidal
- MK McGuire
- MK McGuire
- MK McGuire
- ML Nevins
- ML Nevins
- ML Nevins
- MM Beloti
- MM Bornstein
- MM Ong
- MP Ginebra
- MP Ginebra
- MP Levin
- MR Dragoo
- MR Dragoo
- MR Dragoo
- MS Cohen
- MS Tonetti
- MS Tonetti
- MW Laschke
- MY Wong
- N Blumenthal
- N Markou
- N Markou
- N Price
- NP Lang
- NU Zitzmann
- NU Zitzmann
- O Gauthier
- O Hogset
- P Annalisa
- P Cortellini
- P Cortellini
- P Cortellini
- P Cortellini
- P DiBattista
- P Kotschy
- P Maragos
- P Nygaard-Ăstby
- P Nygaard-Ăstby
- P Pripatnanont
- P Sibilla
- P Valentini
- P Valentini
- P Valentini
- P Valentini
- PA Alffram
- PJ Hanes
- PM Camargo
- PM Trejo
- PN Galgut
- PS Rosen
- PS Rosen
- PS Rosen
- PS Rosen
- PV Giannoudis
- R Detienville
- R Ewers
- R Gupta
- R Kolerman
- R Mengel
- R Mengel
- R Parodi
- R Yukna
- RA Yukna
- RA Yukna
- RA Yukna
- RA Yukna
- RA Yukna
- RA Yukna
- RA Yukna
- RA Yukna
- RA Yukna
- RE Cohen
- RE Marx
- RF Ellinger
- RG Schallhorn
- RG Sorensen
- RJ Harris
- RJ Harris
- RJ Harris
- RJ Kohal
- RR Throndson
- RW Herold
- S Elder
- S Froum
- S Govindaraj
- S Haimi
- S Hattar
- S Hu
- S Karatzas
- S Larsson
- S Movin
- S Nakanishi
- S Oreamuno
- S Pollick
- S Prakash
- S Renvert
- S Renvert
- S Schou
- S Shahmiri
- S Sukumar
- S Taschieri
- S Yilmaz
- S Ymane
- SA Bender
- SB Lee
- SB Low
- SC Schrad
- SI Stratul
- SI Stratul
- SI Stratul
- SJ Froum
- SJ Froum
- SJ Froum
- SJ Froum
- SJ Froum
- SJ Froum
- SJ Froum
- SJ Meraw
- SK Nandi
- SR Bannister
- SR Winn
- SS Jensen
- SS Jensen
- SS Stahl
- SS Stahl
- SS Stahl
- SS Wallace
- SV Kothiwale
- SW Sapkos
- T Arx von
- T Berglundh
- T Dietrich
- T Dybvik
- T Furusawa
- T Inoue
- T Inoue
- T Ito
- T Kawai
- T Muramatsu
- T Wada
- TB Lovelace
- TC Kuo
- TF Flemmig
- TG Wilson
- TG Wilson
- TJ Blokhuis
- TJ Gao
- TM Turner
- TW Mabry
- U Nannmark
- U Nannmark
- U Ripamonti
- UM Wikesjö
- UM Wikesjö
- V Lekovic
- V Lekovic
- VA Carvalho
- VC Barney
- W Beertsen
- W Renooji
- W Sun
- WCA Vrouwenvelder
- WH Bell
- WH Hiatt
- WT Baldock
- WW Sepe
- XE Dereka
- XE Dereka
- Y Ning
- Y Shirakata
- Y Shirakata
- Y Shirakata
- Y Shirakata
- YC Chiang
- Z Artzi
- Z Artzi
- Z Lu
- Z Lu
- Z Schwartz
- Z Schwartz
- Z Schwartz
- Z Yassibag-Berkman
- Publication venue
- 'Springer Science and Business Media LLC'
- Publication date
- Field of study
Body mass index and complications following major gastrointestinal surgery: a prospective, international cohort study and meta-analysis.
- Author
- 6rhalmi J
- 6zkan Bb
- \u160im\ue1\u10dkov\ue1 B
- \u160irok\ue1 M
- \u17debr\ue1k R
- Aarts E
- Abbas Z
- Abburu S
- Abd Ghaffar Mk
- Abdelgalil R
- Abdelhadi M
- Abdikadir Hr
- Abdulmajid A
- Abdulrahman N
- Abid A
- Abid H
- Abrisqueta Carrion J
- Abuhussein N
- Abul Mh
- Acar S
- Acherman Yiz
- Acquaah F
- Acres M
- Adams R
- Adams Rd
- Adebayo Aa
- Adeleja I
- Adiyaman C
- Adjei H
- Adlan A
- Afzal Z
- Agalar C
- Agarwal V
- Agrawal M
- Ahern N
- Ahmad A
- Ahmad K
- Ahmad S
- Ahmed F
- Ahmed H
- Ahmed M
- Ahmed N
- Ahmed S
- Ahn Js
- Aidoo-Micah Ge
- Aildasani L
- Aithie Jm
- Akbulut F
- Akcaoglu T
- Akdogan A
- Akhtar S
- Akkaya E
- Akkucuk S
- Akpunarli B
- Aksoy K
- Aktas Mk
- Aktekin H
- Al-Mousawi A
- Al-Nasser A
- Al-Nasser Z
- Al-Obaedi O
- Al-Robeye A
- Albayrak D
- Alberdi San Roman I
- Alberti Delgado P
- Alcazar Montero Ja
- Alcocer Bp
- Alconchel-Gago F
- Aldrey I
- Ali A
- Ali B
- Ali H
- Ali M
- Ali S
- Alim Ye
- Aliseda-Jover D
- Alizadeh M
- Aljbour A
- Aljbour I
- Allan C
- Allen Jly
- Allot R
- Alonso Gon\ue7alves S
- Alonso Hernandez N
- Altintas O
- Altomare Df
- Alvarez Reyes I
- Amajuoyi A
- Amarelo Garcia M
- Ambrona-Zafra D
- Amelung Fj
- Amin H
- Amin O
- Amphlett Ah
- Anabitarte O
- Anakwenze V
- Anandarajah C
- Anania G
- Anconelli D
- Anderson L
- Anderson Lb
- Anderson Rgj
- Anderson Sm
- Ang A
- Angelov S
- Anilkumar A
- Anim-Addo N
- Ankarali T
- Ansari N
- Antoniou I
- Anyan-Brown J
- Aonzo P
- Apicella M
- Aquilino F
- Aray E
- Archer Ch
- Archer M
- Arcudi C
- Arenal Jj
- Arezzo A
- Argenti F
- Arif T
- Arora E
- Arrigo A
- Arslan E
- Arslan U
- Arthurs B
- Arukan C
- Arun C
- Asbjoernsen Ca
- Ashfaq U
- Ashken L
- Ashraf S
- Ashraf Sf
- Ashton Aj
- Ashwood J
- Asik M
- Aslan L
- Aslanyan A
- Asma A
- Asmadi A
- Assadullah S
- Atalay H
- Atasoy H
- Atayi A
- Atesavci Sn
- Atif M
- Atraszkiewicz Ba
- Attalla M
- Austreng L
- Auyoung E
- Avery P
- Axelson T
- Ayaz B
- Aydar Seyi
- Aytekin A
- Aziz H
- Aziz N
- Babaoglu H
- Bach S
- Badia Jm
- Badii B
- Badran A
- Baeten Cim
- Bagaglini G
- Bagley J
- Bahcecioglu B
- Baixauli J
- Baker An
- Baker C
- Bakewell Zr
- Bakhsh A
- Baki Be
- Balagna P
- Balaji S
- Balci B
- Baldwin A
- Bali An
- Balian V
- Bamac E
- Bamgbose Fa
- Bandirmali O
- Barai I
- Barmayehvar B
- Barnes J
- Barone V
- Barrera Gomez M
- Barrow Tr
- Barthorpe Ae
- Bartlett J
- Bartlett Rd
- Barto\u161 M
- Barton Ec
- Bartrina Soler P
- Baskoy L
- Bassam N
- Bassett J
- Bassiony S
- Bastiaansen Ajnm
- Bath Mf
- Batho A
- Batt E
- Baykan B
- Bayoumy Ab
- Bayram S
- Bazeer Hz
- Beaver D
- Becerra Nieves M
- Beckett J
- Beecroft S
- Behar N
- Bektur G
- Belia F
- Belibagli Zo
- Bell A
- Bell L
- Bell N
- Bellinato M
- Bellio G
- Beltr\ue1n de Heredia J
- Bemand Tp
- Bemelman Wa
- Benevento A
- Benli S
- Berends F
- Bergara T
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- Medina-Fern\ue1ndez Fj
- Meek J
- Mehdi A
- Mehta Jk
- Meijerink Wjhj
- Menduni N
- Menon A
- Mensink G
- Mericliler M
- Mermer S
- Messina F
- Mestres Petit N
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- Mian A
- Milana F
- Milazzo Lf
- Millan M
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- Mills H
- Mills M
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- Mirallas Vi\uf1as O
- Miranda Bh
- Mirdavoudi V
- Mirza M
- Mishra A
- Mistry Bd
- Mistry S
- Mitchell H
- Mitha N
- Mithrakumar P
- Mitrasinovic S
- Mittapalli D
- Mitxelena Elosegi L
- Mizan Sr
- Mogan Yp
- Mohamed Us
- Mohamud M
- Mohan K
- Mohan M
- Mohite A
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- Montuori M
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- Moradzadeh J
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- Mosterd Cm
- Mugurtay Ys
- Mulder Im
- Muller S
- Mural-Krishnan S
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- Muro M
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- Murtaza A
- Murtaza Mi
- Mushtaq J
- Mustafa S
- Musters Gd
- Mutlu B
- Mutlu D
- Myers L
- Naccari P
- Naccari Pm
- Nachiappan R
- Nadanakumaran K
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- Narain A
- Naran P
- Narang Y
- Narayan P
- Narramore R
- Narwani V
- Navayogaarajah V
- Naveed H
- Nayee H
- Neary A
- Nehikhare I
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- Nelli T
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- Neophytou C
- Nepogodiev D.
- Nesargikar Pn
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- Ng Gs
- Ng Jck
- Ng Jq
- Ng K
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- Ng S
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- Norton J
- Nota Clma
- Notarnicola M
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- O'Bryan M
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- O'Neill Em
- O'Neill S
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- Omara S
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- Orhalmi J
- Orhan K
- Osei-Kuffour D
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- Oudman Ts
- Oun H
- Owasil R
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- Ozben V
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- P\uf6s M
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- Palanivail N
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- Pallara E
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- Palmieri A
- Palmisano S
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- Palyzov\ue1 H
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- Pandey G
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- Parinisi Z
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- Parker J
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- Yilmaz I
- Yilmaz M
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- Yurekli Am
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- Zengin T
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- Zhao J
- Ziff O
- Zigiotto D
- Zijlmans Jl
- Zimmerman D
- Ziprin P
- Zope S
- Zuhair M
- Publication venue
- 'Wiley'
- Publication date
- 01/01/2018
- Field of study
AIM:
Previous studies reported conflicting evidence on the effects of obesity on outcomes after gastrointestinal surgery. The aims of this study were to explore the relationship of obesity with major postoperative complications in an international cohort and to present a meta-analysis of all available prospective data.
METHODS:
This prospective, multicentre study included adults undergoing both elective and emergency gastrointestinal resection, reversal of stoma or formation of stoma. The primary end-point was 30-day major complications (Clavien-Dindo Grades III-V). A systematic search was undertaken for studies assessing the relationship between obesity and major complications after gastrointestinal surgery. Individual patient meta-analysis was used to analyse pooled results.
RESULTS:
This study included 2519 patients across 127 centres, of whom 560 (22.2%) were obese. Unadjusted major complication rates were lower in obese vs normal weight patients (13.0% vs 16.2%, respectively), but this did not reach statistical significance (P = 0.863) on multivariate analysis for patients having surgery for either malignant or benign conditions. Individual patient meta-analysis demonstrated that obese patients undergoing surgery for malignancy were at increased risk of major complications (OR 2.10, 95% CI 1.49-2.96, P < 0.001), whereas obese patients undergoing surgery for benign indications were at decreased risk (OR 0.59, 95% CI 0.46-0.75, P < 0.001) compared to normal weight patients.
CONCLUSIONS:
In our international data, obesity was not found to be associated with major complications following gastrointestinal surgery. Meta-analysis of available prospective data made a novel finding of obesity being associated with different outcomes depending on whether patients were undergoing surgery for benign or malignant disease
Outcomes from elective colorectal cancer surgery during the SARSâCoVâ2 pandemic
- Author
- 6\u11f\ufcc\ufc H
- 6fner D
- 6hlberger L
- \u106oza I
- \uc2ngelo M
- \uc4lg\ue5 A
- \uc7elebi F
- \uc7olak E
- Aawsaj Y
- Abad Gurumeta A
- Abad\u2010Motos A
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- Abbott D
- Abdalla M
- Abdeldayem H
- Abdelkader Salama I
- Abdelkarim M
- Abdur\u2010Rahman L
- Abel MK
- Aboelkassem Ibrahim A
- Abou Chaar MK
- Abou Chaar Mohamad K.
- Abreu da Silva A
- Abubakar A
- Acebes Garc\ueda F
- Achalandabaso Boira M
- Acher A
- Acrich E
- Adamina M
- Adamina Michel
- Ademuyiwa Adesoji O
- Aderombi A
- Adeyeye A
- Adiamah A
- Afonso J
- Agapov M
- Agarwal Arnav
- Aghayeva A
- Agilinko J
- Agnes A
- Agostini C
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- Aguado H
- Aguilar Gonzalez M
- Aguilera Lorena Maria
- Ahmed Z
- Ahmeidat A
- Ahn JH
- Aiken T
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- Akalin M
- Akaydin E
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- Albertsmeiers Markus
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- Publication venue
- 'Wiley'
- Publication date
- 01/01/2020
- Field of study
Aim
This study aimed to describe the change in surgical practice and the impact of SARS-CoV-2 on mortality after surgical resection of colorectal cancer during the initial phases of the SARS-CoV-2 pandemic.
Method
This was an international cohort study of patients undergoing elective resection of colon or rectal cancer without preoperative suspicion of SARS-CoV-2. Centres entered data from their first recorded case of COVID-19 until 19 April 2020. The primary outcome was 30-day mortality. Secondary outcomes included anastomotic leak, postoperative SARS-CoV-2 and a comparison with prepandemic European Society of Coloproctology cohort data.
Results
From 2073 patients in 40 countries, 1.3% (27/2073) had a defunctioning stoma and 3.0% (63/2073) had an end stoma instead of an anastomosis only. Thirty-day mortality was 1.8% (38/2073), the incidence of postoperative SARS-CoV-2 was 3.8% (78/2073) and the anastomotic leak rate was 4.9% (86/1738). Mortality was lowest in patients without a leak or SARS-CoV-2 (14/1601, 0.9%) and highest in patients with both a leak and SARS-CoV-2 (5/13, 38.5%). Mortality was independently associated with anastomotic leak (adjusted odds ratio 6.01, 95% confidence interval 2.58â14.06), postoperative SARS-CoV-2 (16.90, 7.86â36.38), male sex (2.46, 1.01â5.93), age >70 years (2.87, 1.32â6.20) and advanced cancer stage (3.43, 1.16â10.21). Compared with prepandemic data, there were fewer anastomotic leaks (4.9% versus 7.7%) and an overall shorter length of stay (6 versus 7 days) but higher mortality (1.7% versus 1.1%).
Conclusion
Surgeons need to further mitigate against both SARS-CoV-2 and anastomotic leak when offering surgery during current and future COVID-19 waves based on patient, operative and organizational risks