Herramientas informáticas para el fortalecimiento del proyecto educativo “Generación Alternativa”

Con la colaboración de la comunidad que hace parte del grupo Generación Alternativa,nace la necesidad de emprender un proyecto que promueva el mejoramiento de sus actividades a través de herramientas informáticas, que son un índice claro de innovación en la expresión juvenil hacia la sociedad. Al distinguirse por ser un grupo de jóvenes emprendedores, es necesario de distintos personajes para que sus metas sean alcanzadas, por ello se utilizó una metodología en la que se concertarían conceptos en pro del beneficio de dicho colectivo, de ahí la aplicación de la investigación acción participación, la cual permite a su vez trabajar concertadamente con la comunidad. El desarrollo de este trabajo se inicio con un diagnostico inicial, en donde se recogieron las particularidades del grupo de trabajo, la dinámica en la realización de sus producciones,necesidades evidenciadas y carencias, todas ellas vitales para las etapas posteriores. Con toda esta valiosa información recolectada, se diseño una propuesta, en la que se abordarían todas las necesidades obtenidas de la etapa inicial; debido a las bondades de esta metodología todas las propuestas fueron puestas a consideración con el propósito de que no fueran impuestas arbitrariamente por los investigadores, sino por el contrario se deseaba que fueran pactadas con los participantes directos del grupo, estudiantes, padres de familia y coordinadora con el ánimo de que dichas soluciones involucren todos los aspectos a mejorar. Una vez ejecutadas estas iniciativas, bajo la tutela de los investigadores y con el apoyo de instituciones tales como la Universidad de Nariño, se entran a evaluar todas y cada una de las estrategias aplicadas en el desarrollo del proyecto, con miras de revisar su impacto. Tras el trabajo desarrollado, se logró la consecución de objetivos tales como la implementación de herramientas informáticas en la producción de contenidos para diversos medios de comunicación, además se fortalecieron aspectos grupales que permiten su sostenibilidad en el largo plazo; de la evaluación se extrajeron aspectos relevantes tales como, la proyección de convertir al colectivo en una ONG, así los jóvenes podrán contar con mayores recursos que permitirán adquirir mejores herramientas de trabajo, capacitaciones y demás elementos que amplíen su campo de acción

Clutch size in great tits (Parus major) in orange-groves of Valencia and in the holm oak forest of Monte Poblet (Tarragona)

La estación de nidificación del Carbonero Común (Parus major) en la franja mediterránea ibérica comienza en abril y finaliza en julio. No obstante, la fecha media de puesta es diferente en distintas localidades. El tamaño medio de la puesta gira en torno a los 7 huevos por nido en las localidades estudiadas. Este valor es diferente del tamaño de la puesta al norte de los Pirineos y en regiones más occidentales de la Península Ibérica.In the Iberian Mediterranean area, the Great Tit's breeding season starts in April and finishes in July, but the mean laying date differs in different areas. The mean clutch size is about 7 eggs in the study sites. This values is significantly lower than mean clutch size both in more northern localities and in Salamanca (western Spain)

Elaboración de modelos de la distribución de la tórtola europea (Streptopelia turtur L. 1758) en el sureste de la península ibérica

The European turtle dove population and breeding range has declined sharply in Spain. This study reanalyses data from the Atlas of Breeding Birds in Alicante (SE Spain), aiming to identify the main variables related to its occurrence and abundance. We used hierarchical partitioning analysis to identify important environmental variables associated with natural vegetation, farming, hydrological web, anthropic presence, climate, and topography. Analysis combining the most explicative variables of each group identified the mixture of pines and scrubland in the semiarid areas and the length of unpaved roads as the most important variables with a positive effect on occurrence, while herbaceous crops and scrublands in dry ombrotype climate areas had the most important negative effect. Abundance was related only to the availability of water points. We discuss the implications of these findings for habitat management in conservation of this species.La población y el área de reproducción de la tórtola europea han disminuido considerablemente en España. En el presente estudio realizamos un nuevo análisis de los datos obtenidos para la elaboración del Atlas de Aves Reproductoras de Alicante (SE de España) con el objetivo de identificar las principales variables relacionadas con la presencia y la abundancia de esta especie. Utilizamos el análisis de partición jerárquica para identificar estas variables ambientales (vegetación natural, agricultura, red hidrológica, presencia antrópica, clima y topografía). El análisis que combinó las variables más explicativas de cada grupo permitió determinar que la mezcla de pinos y matorrales en zonas semiáridas y a lo largo de las carreteras sin asfaltar es la variable que tuvo el mayor efecto positivo en la presencia de la tórtola, mientras que la mezcla de cultivos herbáceos y matorrales en el ombrotipo seco es la que tuvo el mayor efecto negativo. La abundancia solo se relacionó con la disponibilidad de puntos de agua. Se discuten las implicaciones de estos resultados con respecto a la gestión del hábitat para la conservación de esta especie

Chemoselective Preparation of New Families of Phenolic-Organoselenium Hybrids—A Biological Assessment

Being aware of the enormous biological potential of organoselenium and polyphenolic compounds, we have accomplished the preparation of novel hybrids, combining both pharma-cophores in order to obtain new antioxidant and antiproliferative agents. Three different families have been accessed in a straightforward and chemoselective fashion: carbohydrate-containing N-acylisoselenoureas, N-arylisoselenocarbamates and N-arylselenocarbamates. The nature of the organoselenium framework, number and position of phenolic hydroxyl groups and substituents on the aromatic scaffolds afforded valuable structure–activity relationships for the biological as-says accomplished: antioxidant properties (antiradical activity, DNA-protective effects, Glutathione peroxidase (GPx) mimicry) and antiproliferative activity. Regarding the antioxidant activity, selenocar-bamates 24–27 behaved as excellent mimetics of GPx in the substoichiometric elimination of H2O2 as a Reactive Oxygen Species (ROS) model. Isoselenocarbamates and particularly their selenocarbamate isomers exhibited potent antiproliferative activity against non-small lung cell lines (A549, SW1573) in the low micromolar range, with similar potency to that shown by the chemotherapeutic agent cisplatin (cis-diaminodichloroplatin, CDDP) and occasionally with more potency than etoposide (VP-16).Ministerio de Ciencia e Innovación PID2020-116460RB-I00Junta de Andalucía FQM134Gobierno de las Islas Canarias ProID202001010

Selección del paisaje urbano de la tórtola turca (Streptopelia decaocto) en el este de España

The Eurasian collared dove (Streptopelia decaocto) is an invasive species, and its distribution is continuously on the increase. Today its expansion has spread to the American continent. In this study we describe the effects of the urban environment on the Eurasian collared dove in eastern Spain. The abundance and presence of this dove were analyzed in 46 localities using counting points. Overall, 220-point counts were surveyed between autumn 2015 and late-winter 2016. A hierarchical partitioning analysis was used to identify explanatory variables of different types such as resources, climate and urban structure, and human presence, which may influence the presence and abundance of this species. In the case of presence, the number of town inhabitants, parks, mean minimum temperature, exotic vegetation and schools had a positive association, while pedestrian number and restaurants had a negative association. Abundance was positively related to native vegetation, exotic vegetation, and water, while urban area was negatively associated with it. Exotic vegetation was the only variable that has a positive relation to presence and abundance. These results can help to predict the use of urban habitats in potential localities for its invasion.La tórtola turca (Streptopelia decaocto) es una especie invasora y su ámbito de distribución aumenta continuamente. Hoy en día, su expansión incluye el continente americano. En este estudio se describen los efectos que el ambiente urbano tiene sobre la tórtola turca en el este de España. Se muestrearon 46 localidades mediante puntos de conteo. La abundancia de la tórtola turca fue evaluada en 220 puntos de conteo entre otoño de 2015 y finales de invierno 2016. Se utilizó el análisis de partición jerárquica para identificar variables explicativas como recursos, clima y estructura urbana, y presencia humana, que pueden influir en su presencia y abundancia. En el caso de la presencia de la especie, el número de habitantes de la ciudad, parques, temperatura media, vegetación exótica y colegios tuvieron una asociación positiva, mientras que el número de peatones y los restaurantes estuvieron negativamente asociados. La abundancia estuvo positivamente relacionada con la vegetación nativa, vegetación exótica y el agua, mientras que la zona urbana estuvo negativamente asociada. Estos resultados pueden predecir el uso de hábitats urbanos en localidades potenciales para su invasión.This research was partially supported by a PhD grant of the Generalitat Valenciana and the European Social Fund (E. B-P., grant number ACIF/2018/015)

IAA : Información y actualidad astronómica (2)

Sumario : Investigación: La misión Envisat.-- Una década de investigación con el telescopio espacial Hubble.-- Ventana Abierta: ¿Ciencias o letras?...Jose Carlos del Toro Iniesta.-- Charlas con...John Huchra.-- Especial: 25 años del IAA.-- Actualidad Científica: Plano a gran escala, tal vez, pero no euclídeo.-- Detección óptica de impactos en la cara oscura de la Luna.-- Actividades IAA.-- Agenda.N

Mangifera indica L. extract tablets supplementation in patients with knee osteoarthritis pain. A controlled pilot study.

Context: Several experimental results and clinical reports using Mangifera indica L extract (MSBE) suggest its potential utility in osteoarthritis (OA) mixed pain. Aims: To examine the possible therapeutic effects and safety of supplementation on osteoarthritis (OA) pain. Methods: Fifty patients with painful knee OA who had undergone a year of conventional treatment that included paracetamol and non-pharmacological therapies were randomly allocated to the experimental group (n = 21), which received a daily dose of 900 mg of extract supplementation or preceding usual treatment and placebo in the same form (n = 17) for a period of 120 days. The primary measure outcome was the change in the average daily pain diary score (ADPS) using the Likert scale. Also, a multidimensional measure of pain, stiffness and functional disability on The Western Ontario and Mc Master Universities (WOMAC) index for knee OA and ultrasonographic chronic signs of synovitis such as effusion and synovial thickness were evaluated. Results: Change from baseline in ADPS of the MSBE supplemented group showed a significant reduction after two weeks that lasted for 120 days with respect to the placebo group. Significant improvements in pain and functional disability WOMAC sub-scores, number of joints with synovial thickness and effusion after MSBE supplementation vs. placebo were observed. Non-adverse effects were reported in the experimental group. Conclusions: These results suggest that MSBE supplementation has a beneficial effect on OA pain and disability

Morphological and morphometric assessment of the encephalic ventricles using different neuroimaging techniques

[ES]An exhaustive analysis of the morphology and morphometry of the encephalic ventricles has been carried out using an array of diagnostic imaging techniques; namely, ultrasound, computerised tomography, magnetic resonance and its three-dimensional variant. The study was conducted on a total of 822 patients ranging in age from birth to 89 years old. The incorporation of these techniques into the field of Human Anatomy has permitted researchers to gain a different and updated view of the anatomical structures present in living human beings. Thus, using ultrasound the ventricular system was identified in the form of sonolucent or anechoic areas. With computerised tomography, the ventricles appeared as hypodense images within the adjacent cerebral parenchyma. With magnetic resonance, and three-dimensional reconstruction, the ventricular morphology was visualised on the three spatial planes. Visualisation of the ventricular cavities by MR varied depending on whether they were enhanced in T1 or T2, or in proton density. From the morphometric point of view, the cerebral ventricles exhibited variations in size that were directly related to the age of the patient; thus, age is a determinant factor in ventricular size. However, note should be taken of the low morphometric variability seen in IVv with respect to age. Regarding the other cerebral ventricles, size did depend on age

Spatial synchrony of wader populations in inland lakes of the Iberian Peninsula

Spatial synchronization refers to similarity in temporal variations between spatially separated populations. Three mechanisms have been associated with the spatial synchrony of populations: Moran effect, dispersal and trophic interactions. In this study, we explored the degree of spatial synchrony of three wader species populations (Pied Avocet, Black-winged Stilt and Kentish Plover) using monthly estimates of their abundance in inland lakes of the Iberian Peninsula. The effect of several types of wetland variables (structural, hydroperiod and landscape) on spatial synchronization was explored. Groups of lakes with significant synchronization were identified for all three species. The lakes with wastewater input presented longer hydroperiods than those that did not receive these effluents, and this factor was positively related to the spatial synchrony of the Pied Avocet and Kentish Plover populations. The distance between lakes (used as an indicator of the dispersal effect on synchronization) was significant only in Pied Avocet. No structural or landscape variables were related to spatial synchronization in any species. It was impossible to identify any variable related to the spatial synchronization of Black-winged Stilt abundance as a possible result of the high ecological plasticity of this species. Our data provides the first evidence for mechanisms that act on the spatial synchronizing of wader populations in temporary continental lakes in central Spain, and show that the hydroperiod of lakes acts as an important factor in the spatial synchronization of aquatic species and that its effect is mediated by the reception of urban wastewater.This study forms part of the doctoral thesis of M. S. S. G. and was supported by a grant from CAPES—Coordenação de Aperfeiçoamento de Pessoal de Nível Superior, Brazil. The present work was performed within the Project ECOLAKE “Ecological patterns in endorheic lakes: the keys to their conservation, CGL2012-38909” (Universidad de Valencia), funded by the Spanish Ministry of Economy and Competitiveness, and by the European Union through the European Fund for Regional Development (FEDER) “One way to make Europe”

Hepatic insulin resistance both in prediabetic and diabetic patients determines postprandial lipoprotein metabolism: from the CORDIOPREV study

Background/aims: Previous evidences have shown the presence of a prolonged and exaggerated postprandial response in type 2 diabetes mellitus (T2DM) and its relation with an increase of cardiovascular risk. However, the response in prediabetes population has not been established. The objective was to analyze the degree of postprandial lipemia response in the CORDIOPREV clinical trial (NCT00924937) according to the diabetic status. Methods: 1002 patients were submitted to an oral fat load test meal (OFTT) with 0.7 g fat/kg body weight [12 % saturated fatty acids (SFA), 10 % polyunsaturated fatty acids (PUFA), 43 % monounsaturated fatty acids (MUFA), 10 % protein and 25 % carbohydrates]. Serial blood test analyzing lipid fractions were drawn at 0, 1, 2, 3 and 4 h during postprandial state. Postprandial triglycerides (TG) concentration at any point >2.5 mmol/L (220 mg/dL) has been established as undesirable response. We explored the dynamic response in 57 non-diabetic, 364 prediabetic and 581 type 2 diabetic patients. Additionally, the postprandial response was evaluated according to basal insulin resistance subgroups in patients non-diabetic and diabetic without pharmacological treatment (N = 642). Results: Prevalence of undesirable postprandial TG was 35 % in non-diabetic, 48 % in prediabetic and 59 % in diabetic subgroup, respectively (p < 0.001). Interestingly, prediabetic patients displayed higher plasma TG and large triacylglycerol- rich lipoproteins (TRLs-TG) postprandial response compared with those non-diabetic patients (p < 0.001 and p = 0.003 respectively). Moreover, the area under the curve (AUC) of TG and AUC of TRLs-TG was greater in the prediabetic group compared with non-diabetic patients (p < 0.001 and p < 0.005 respectively). Patients with liver insulin resistance (liver-IR) showed higher postprandial response of TG compared with those patients with muscle-IR or without any insulin-resistance respectively (p < 0.001). Conclusions: Our findings demonstrate that prediabetic patients show a lower phenotypic flexibility after external aggression, such as OFTT compared with nondiabetic patients. The postprandial response increases progressively according to non-diabetic, prediabetic and type 2 diabetic state and it is higher in patients with liver insulin-resistance. To identify this subgroup of patients is important to treat more intensively in order to avoid future cardiometabolic complications