151 research outputs found

    TECNOLOGÍA, META-TECNOLOGÍA Y EDUCACIÓN

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    El artículo reflexiona acerca de las relaciones existentes entre “tecnología, meta-tecnología y educación”, considera que la referencia a la tecnología en su vínculo con la educación involucra de modo inmediato la presencia de dispositivos técnicos resultantes de la revolución científicotecnológica, los desarrollos recientes de las comunicaciones y la microelectrónica. La tecnología sigue siendo una entidad cuyo reconocimiento en las sociedades contemporáneas se acompaña de profundos desconocimientos y paradojas que obligan a revisar las tecnologías educativas a través del prisma de las paradojas.The article thinks brings over of the existing relations between “ technology, goal - technology and education “, thinks that the reference to the technology in his link with the education involves in an immediate way the presence of technical resultant devices of the scientific - technological revolution, the recent developments of the communications and the microelectronics. The technology continues being an entity which recognition in the contemporary companies accompanies of deep ignorances and paradoxes that force to check the educational technologies across the prism of the paradoxes

    Tecnología Meta-Tecnología Educación

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    El artículo reflexiona acerca de las relaciones existentes entre “tecnología, meta-tecnología y educación”, considera que la referencia a la tecnología en su vínculo con la educación involucra de modo inmediato la presencia de dispositivos técnicos resultantes de la revolución científico-tecnológica, los desarrollos recientes de las comunicaciones y la microelectrónica. La tecnología sigue siendo una entidad cuyo reconocimiento en las sociedades contemporáneas se acompaña de profundos desconocimientos y paradojas que obligan a revisar las tecnologías educativas a través del prisma de las paradojas

    La complejidad y el diálogo transdisciplinario de saberes

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    Capítulo del libro La revolución contemporánea del saber y la complejidad social. Hacia unas ciencias sociales de nuevo tipo

    Propuesta de Startups con el Modelo Canvas de los estudiantes de Planeamiento Estratégico I de la Facultad de Ingeniería - UNTRM

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    A nivel internacional los startups tienen un impacto importante en la economía y calidad de vida de la población, por ello es importante comprender su ecosistema. En esta investigación se planteó el objetivo general: analizar la propuesta de startups con el Modelo Canvas de los estudiantes de Planeamiento Estratégico I de la FISME - UNTRM – Bagua. Metodología: se han seleccionado 28 documentos, realizados en el periodo 2017 - 2022; incluyendo: artículos científicos, artículos de revisión e información de sitios web de organizaciones reconocidas. Las palabras claves utilizadas en las búsquedas fueron: Startup, inversores ángeles y modelo Canvas. Resultados: se presentaron 5 casos de estudio, que comprenden la propuesta de startups con el modelo Canvas de los estudiantes de Planeamiento Estratégico I de la FISME - UNTRM – BAGUA. Estos fueron: Productos de belleza y salud con aceite de coco, Fast delivery con drones, Vivero digital Bagua, Amazonas delivery y Locattle dispositivo de rastreo. La propuesta de startups ha sido realizada con el fin de ofrecer soluciones a problemas identificados por los estudiantes con la asesoría del docente del curso. Conclusiones: cada día cobra mayor importancia la creación de startups en el Perú, por lo que resulta necesario incrementar el apoyo. Los inversores ángeles juegan un papel importante en el financiamiento de los startups y el acompañamiento sobre todo en las primeras fases. Cada vez hay una mayor presencia de estos inversores en el Perú. El modelo Canvas resulta fundamental para los emprendedores en el desarrollo de sus proyectos, por lo que debemos fomentar su difusión en la academia. Los 5 casos de estudio, que comprenden la propuesta de startups con el modelo Canvas de los estudiantes de Planeamiento Estratégico I de la FISME - UNTRM – BAGUA, demuestran innovación y actitud emprendedora

    Integral analysis of environmental and economic performance of combined agricultural intensification & bioenergy production in the Orinoquia region

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    Agricultural intensification is a key strategy to help meet increasing demand for food and bioenergy. It has the potential to reduce direct and indirect land use change (LUC) and associated environmental impacts while contributing to a favorable economic performance of the agriculture sector. We conduct an integral analysis of environmental and economic impacts of LUC from projected agricultural intensification and bioenergy production in the Orinoquia region in 2030. We compare three agricultural intensification scenarios (low, medium, high) and a reference scenario, which assumes a business-as-usual development of agricultural production. The results show that with current inefficient management or with only very little intensification between 26% and 93% of the existing natural vegetation areas will be converted to agricultural land to meet increasing food demand. This results in the loss of biodiversity by 53% and increased water consumption by 111%. In the medium and high scenarios, the intensification allows meeting increased food demand within current agricultural lands and even generating surplus land which can be used to produce bioenergy crops. This results in the reduction of biodiversity loss by 8-13% with medium and high levels of intensification compared to the situation in 2018. Also, a positive economic performance is observed, stemming primarily from intensification of cattle production and additional energy crop production. Despite increasing irrigation efficiency in more intensive production systems, the water demand for perennial crops and cattle production over the dry season increases significantly, thus sustainable management practices that target efficient water use are needed. Agricultural productivity improvements, particularly for cattle production, are crucial for reducing the pressure on natural areas from increasing demand for both food products and bioenergy. This implies targeted investments in the agricultural sector and integrated planning of land use. Our results showed that production intensification in the Orinoquia region is a mechanism that could reduce the pressure on natural land and its associated environmental and economic impacts

    La memoria del jurista español. Estudios

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    La publicación se propone profundizar en el conocimiento de las características y la evolución de las enseñanzas jurídicas en las universidades españolas durante la etapa liberal. No lo hace a través de una visión panorámica, ni siquiera de un conjunto de ellas. Los temas y enfoque que encontrará el lector muestran piezas individuales que sin embargo adquieren un significado más pleno al insertarse en el volumen. Tribunales de oposición y escuelas, la evolución de las asignaturas dedicadas a la economía, la peculiaridad del derecho mercantil, el contexto académico del proyecto de Código civil de 1851, la biografía de Juan Moneva Puyol, el antifeminismo jurídico, la metodología docente, los exilios... son algunas claves a través de las cuales podemos penetrar en la cultura jurídica liberal de España.Esta publicación forma parte del proyecto “La memoria del jurista español: génesis y desarrollo de las disciplinas jurídicas” (ref. DER2014-55035-C2-1-P/DER2014-55035-C2-2-P), financiado por el Ministerio de Economía, Industria y Competitividad (España).Presentación / Miguel Ángel Bermejo Castrillo (pp. 9-12). -- Juan Moneva Puyol: un jurista de novela, un hombre para toda ocasión / Jesús Bogarín Díaz (pp. 13-57). -- James Goldschmidt y la doctrina procesal española de entreguerras / Manuel Cachón Cadenas (pp. 59-84). -- Evolución de las materias económicas en las facultades de Derecho españolas del siglo XIX / Mariano Castro-Valdivia (pp. 85-116). -- La muralla china, el primer antifeminismo jurídico / Esteban Conde Naranjo (pp. 117-163). -- La Escuela de Valladolid de Derecho Civil en el siglo XIX. Con algunas reflexiones sobre maestros y discípulos / Jesús Delgado Echeverría (pp. 165-184). -- Un estudiante de Derecho en la Facultad de Zaragoza en los años sesenta. Recuerdos, memoria e historia / Jesús Delgado Echeverría (pp. 185-204). -- Los tribunales de oposiciones y otras peripecias de las provisiones de cátedras de Derecho (1859-1936) / Javier Carlos Díaz Rico (pp. 205-246). -- Sebastian Haffner. Fantasía y filosofía en el centenario de Weimar / Federico Fernández-Crehuet (pp. 247-257). -- De la autoridad del padre y de la familia cristiana ante el proyecto codificador de 1851. A propósito de un discurso inaugural de curso académico: Universidad de Barcelona, otoño de 1857 / Alessandra Giuliani (pp. 259-299). -- La cátedra de instituciones de Derecho Canónico de la Universidad de Murcia: las oposiciones de 1917 / Fernando Hernández Fradejas (pp. 301-334). -- En tierra extraña. Juristas españoles en el exilio neoyorkino / Aurora María López-Medina (pp. 335-350). -- Egoísmo y derecho mercantil. Textos y contextos del Manual de Eduardo Soler (1882). -- Carlos Petit (pp. 351-382). -- De Berlín a Buenos Aires: el trasplante del método de casos en Argentina / Enrique Roldán Cañizares (pp. 383-416)

    Brown bear behaviour in human-modified landscapes: The case of the endangered Cantabrian population, NW Spain

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    Large carnivores are recolonizing parts of their historical range in Europe, a heavily modified human landscape. This calls for an improvement of our knowledge on how large carnivores manage to coexist with humans, and on the effects that human activity has on large carnivore behaviour, especially in areas where carnivore populations are still endangered. Brown bears Ursus arctos have been shown to be sensitive to the presence of people and their activities. Thus, bear conservation and management should take into account potential behavioural alterations related to living in human-modified landscapes. We studied the behaviour of brown bears in the Cantabrian Mountains, NW Spain, where an endangered population thrives in a human-modified landscape. We analysed bear observations video-recorded over a 10-year period to try to identify human and landscape elements that could influence bear behaviour. Neither the occurrence nor the duration of vigilance behaviour in Cantabrian bears seemed to be influenced by the proximity of human infrastructures and activity. Our findings suggest that the general pattern of human avoidance by bears is adapted to the human-modified landscape they inhabit. Bears generally avoid people, but close presence of human infrastructures or activity did not seem to trigger an increased bear behavioural response. Coexistence between large carnivores and humans in human-modified landscapes is possible, even when human encroachment is high, provided that carnivores are not heavily persecuted and direct interactions are avoided. Further research should also document the potential existence of other responses to human presence and activity, e.g., hunting, traffic noise, and measuring stress levels with physiological indicators.This research was financially supported by the IBA (International Association for Bear Research and Management) grant project IBA-RG_16_2016 ‘Brown bear behaviour in human-dominated landscapes: the effect of human density and ecotourism’. During this research, G.B. was financially supported by a collaboration contract with the MUSE – Museo delle Scienze of Trento (Italy), J.M-P. was supported by the ARAID foundation and V.P., A.O. and R.G.G. were also financially supported by the Excellence Project CGL2017-82782-P financed by the Spanish Ministry of Economy, Industry and Competitiveness (MINECO), the Agencia Estatal de Investigación (AEI) and the Fondo Europeo de Desarrollo Regional (FEDER, EU)

    In vivo murine model of acquired resistance in myeloma reveals differential mechanisms for lenalidomide and pomalidomide in combination with dexamethasone

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    The development of resistance to therapy is unavoidable in the history of multiple myeloma patients. Therefore, the study of its characteristics and mechanisms is critical in the search for novel therapeutic approaches to overcome it. This effort is hampered by the absence of appropriate preclinical models, especially those mimicking acquired resistance. Here we present an in vivo model of acquired resistance based on the continuous treatment of mice bearing subcutaneous MM1S plasmacytomas. Xenografts acquired resistance to two generations of immunomodulatory drugs (IMiDs; lenalidomide and pomalidomide) in combination with dexamethasone, that was reversible after a wash-out period. Furthermore, lenalidomide-dexamethasone (LD) or pomalidomide-dexamethasone (PD) did not display cross-resistance, which could be due to the differential requirements of the key target Cereblon and its substrates Aiolos and Ikaros observed in cells resistant to each combination. Differential gene expression profiles of LD and PD could also explain the absence of cross-resistance. Onset of resistance to both combinations was accompanied by upregulation of the mitogen-activated protein kinaseextracellular signal-regulated kinase (ERK) kinase (MEK)ERK pathway and addition of selumetinib, a small-molecule MEK inhibitor, could resensitize resistant cells. Our results provide insights into the mechanisms of acquired resistance to LD and PD combinations and offer possible therapeutic approaches to addressing IMiD resistance in the clinic.Peer Reviewe

    Galaxy clusters and groups in the ALHAMBRA Survey

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    We present a catalogue of 348 galaxy clusters and groups with 0.2<z<1.20.2<z<1.2 selected in the 2.78 deg2deg^2 ALHAMBRA Survey. The high precision of our photometric redshifts, close to 1%1\%, and the wide spread of the seven ALHAMBRA pointings ensure that this catalogue has better mass sensitivity and is less affected by cosmic variance than comparable samples. The detection has been carried out with the Bayesian Cluster Finder (BCF), whose performance has been checked in ALHAMBRA-like light-cone mock catalogues. Great care has been taken to ensure that the observable properties of the mocks photometry accurately correspond to those of real catalogues. From our simulations, we expect to detect galaxy clusters and groups with both 70%70\% completeness and purity down to dark matter halo masses of Mh3×1013MM_h\sim3\times10^{13}\rm M_{\odot} for z<0.85z<0.85. Cluster redshifts are expected to be recovered with 0.6%\sim0.6\% precision for z<1z<1. We also expect to measure cluster masses with σMhMCL0.250.35dex\sigma_{M_h|M^*_{CL}}\sim0.25-0.35\, dex precision down to 3×1013M\sim3\times10^{13}\rm M_{\odot}, masses which are 50%50\% smaller than those reached by similar work. We have compared these detections with previous optical, spectroscopic and X-rays work, finding an excellent agreement with the rates reported from the simulations. We have also explored the overall properties of these detections such as the presence of a colour-magnitude relation, the evolution of the photometric blue fraction and the clustering of these sources in the different ALHAMBRA fields. Despite the small numbers, we observe tentative evidence that, for a fixed stellar mass, the environment is playing a crucial role at lower redshifts (z<<0.5).Comment: Accepted for publication in MNRAS. Catalogues and figures available online and under the following link: http://bascaso.net46.net/ALHAMBRA_clusters.htm
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