Corrigendum to “The effect of intrauterine human chorionic gonadotropin injection before embryo transfer on the implantation and pregnancy rate in infertile patients: A randomized clinical trial” [Int J Reprod BioMed 2016; 14: 657-664]

The authors have been informed of an error that occurred on page 657 in which the IRCT code has been entered incorrectly, which should be corrected as: “IRCT2012091310328N3”. On behalf of the author, the publisher wishes to apologize for this error. The online version of article has been updated on 31 January 2023 and can be found at https://doi.org/10.18502/ijrm.v14i10.695

Maternal and neonatal outcomes among pregnant women with different polycystic ovary syndrome phenotypes: A cross-sectional study

Background: Pregnancy is a process associated with various metabolic and hormonal changes, and polycystic ovary syndrome (PCOS) can affect this process. Objective: This study aimed to evaluate and compare the maternal and neonatal outcomes among pregnant women with different polycystic ovary syndrome phenotypes. Materials and Methods: In this cross-sectional study, 200 pregnant women with PCOS according to the 2003 ESHRE/ASRM criteria were categorized into four phenotype groups (A-D). The maternal outcomes include gestational diabetes mellitus, pregnancy-induced hypertension, premature rupture of membranes, preterm labor, small-for-gestational age birth, intrauterine growth restriction, intrauterine mortality, preeclampsia, abortion, amniotic fluid disorders, delivery method, and cause of cesarean section were studied between groups. Additionally, neonatal outcomes such as neonatal weight, neonatal recovery, 5-min Apgar score, neonatal icter, the need for NICU admission, the cause of hospitalization, and infant mortality rate were investigated and compared among the groups. Results: According to the results, phenotype D (37%) was the most common phenotype among the participants. The risk of gestational diabetes was more common in phenotype A than in the other phenotypes, whereas pregnancy-induced hypertension was most common in phenotype B. No significant differences were observed in the neonatal complications among the PCOS phenotypes. Conclusion: Considering the higher risk of gestational diabetes mellitus and pregnancy-induced hypertension in PCOS phenotypes A and B, women with these phenotypes need more precise prenatal care. Key words: Pregnancy outcome, Polycystic ovary syndrome, Phenotype, Pregnancy

Outcome of cryopreserved-thawed embryo transfer in the GnRH agonist versus antagonist protocol

Abstract Background: GnRH agonist and antagonist were developed to control the premature release of LH surge. There is some difference between two protocols. Objective: We compared the outcome of frozen-thawed embryo transfer in infertile women who used GnRH agonist or antagonist protocol for previous COH cycle and evaluation of any adverse effect of GnRH antagonist on oocyte and embryo. Materials and Methods: The study group included all infertile women who referred to Yazd Research and Clinical Center for Infertility. Overall 20-35 years old women who were candidate for frozen-thawed embryo transfer with regard to inclusion and exclusion criteria were participated in the study. The patients based on previous control ovarian stimulation (COH) protocol divided in to two groups: GnRH agonist long protocol (n=165) and GnRH antagonist multiple dose protocol (n=165). Frozen-thawed embryos were transferred after endometrial preparation in both groups. Main outcome measures were: implantation, chemical and clinical pregnancy rate. Results: The implantation and clinical pregnancy rate following cryopreserved embryo transfer in GnRH agonist group and antagonist group were 16.3% vs. 15.7% (p=0.806) and 38.1% (63/165) vs. 36.9% (61/165) (p=0.915) and chemical pregnancy rate was 44.8% (74/165) vs. 43.6% (72/165) (p=0.915) respectively. Conclusion: There was no statistically difference between two groups in terms of implantation and pregnancy rate. Although pregnancy rate in fresh embryo transfer in antagonist cycles was lower than agonist groups, Therefore decrease in these parameters might be due to detrimental effect of GnRH antagonist on the endometrium, not embryo or oocyte

Value of follicular fluid vitamin D in predicting the pregnancy rate in an IVF program

Purpose This study investigated whether there is a correlation between levels of 25OH-D in the follicular fluid and the serum of infertile women and the results of IVF and rates of pregnancy. The association between the levels of 25OH-D in the follicular fluid and the vitamin D repletion status was also assessed. Methods Two hundred and twenty-one infertile women participated in an IVF cycle from 2010 to 2011 in a prospective observational study. Serum and follicular fluid were collected for vitamin D analysis. Deficient, insufficient, and sufficient levels of vitamin D were defined as 10, 10–29, and 30–100 ng/ml, respectively. IVF cycle parameters and clinical pregnancy rates were also compared with the vitamin D level. Results The levels of vitamin D deficiency, insufficiency, and sufficiency were 22.6, 70.1, and 7.2 %, respectively. The fertilization rates associated with these three levels of vitamin D were 43.17, 53.37, and 58.77 %, respectively, (P = 0.054), and the implantation rates were 17.33, 15.26, and 18.75 %, respectively, (P = 0.579). No significant correlation was seen between the pregnancy rate and the serum vitamin D level (P = 0.094) or the follicular vitamin D level (P = 0.170). The serum and follicular fluid vitamin D levels showed a significant correlation (P = 0.000). Conclusion Although vitamin D is an important hormone in the human body, no correlation was found between the serum and follicular vitamin D level and the pregnancy rate in the IVF cycle. Keywords Vitamin D � IVF � Follicular fluid � Pregnancy rate � 250H-

On Understanding the Relation of Knowledge and Confidence to Requirements Quality

Context and Motivation: Software requirements are affected by the knowledge and confidence of software engineers. Analyzing the interrelated impact of these factors is difficult because of the challenges of assessing knowledge and confidence. Question/Problem: This research aims to draw attention to the need for considering the interrelated effects of confidence and knowledge on requirements quality, which has not been addressed by previous publications. Principal ideas/results: For this purpose, the following steps have been taken: 1) requirements quality was defined based on the instructions provided by the ISO29148:2011 standard, 2) we selected the symptoms of low qualified requirements based on ISO29148:2011, 3) we analyzed five Software Requirements Specification (SRS) documents to find these symptoms, 3) people who have prepared the documents were categorized in four classes to specify the more/less knowledge and confidence they have regarding the symptoms, and 4) finally, the relation of lack of enough knowledge and confidence to symptoms of low quality was investigated. The results revealed that the simultaneous deficiency of confidence and knowledge has more negative effects in comparison with a deficiency of knowledge or confidence. Contribution: In brief, this study has achieved these results: 1) the realization that a combined lack of knowledge and confidence has a larger effect on requirements quality than only one of the two factors, 2) the relation between low qualified requirements and requirements engineers' needs for knowledge and confidence, and 3) variety of requirements engineers' needs for knowledge based on their abilities to make discriminative and consistent decisions.Comment: Preprint accepted for publication at the 27th International Working Conference on Requirement Engineering: Foundation for Software Qualit

The Effect of Listening to the Quran Verses on the Happiness of Girl Students of Junior High School in Borujen

Background: Happiness among students can enhance school performance. The aim of this study was to investigate the effect of listening to the Quran verses on the happiness of female students of a junior high school in Borujen, Iran. Methods: In this semi-experimental study, all students of the 2nd grade of the Distinct Governmental Junior High School in Borujen, Iran, were included by census sampling method. Data were collected by the Oxford Happiness Questionnaire completed by the students. Then, the verses of Hashr sura recited by Mahmoud Minshavi were replayed for one week. After this, the questionnaires were completed by the students again. Finally, the data were analyzed by paired t-tests using SPSS 15. Results: In this study, 92 girl students of Junior High School with an average age of 13.57±0.49 were included. The average score of happiness before and after listening to the Quran verses were 60.39±10.69 and 67.58±14.30, respectively. The scores of happiness significantly increased (P<0.001). Conclusion: The findings show that Quran recitation probably increases the happiness of the students. Therefore, by planning to have Quran recitation in schools, the level of students’ happiness can be increased

Fusion of retrieval models at CLEF 2008 Ad Hoc Persian Track

Metasearch engines submit the user query to several under- lying search engines and then merge their retrieved results to generate a single list that is more e®ective to the users information needs. According to the idea behind metasearch engines, it seems that merging the results retrieved from di®erent retrieval models will improve the search coverage and precision. In this study, we have investigated the e®ect of fusion of di®erent retrieval techniques on the performance of Persian retrieval. We use an extension of Ordered Weighted Average (OWA) operator called IOWA and a weighting schema, NOWA for merging the results. Our ex- perimental results show that merging by OWA operators produces better MAP

Role of hyaluronic acid intrauterine injection in the prevention of Asherman’s syndrome in women undergoing uterine septum resection: An RCT

Background: Adhesion due to intrauterine surgery such as septal resection associated with damaged endometrium can increase the risk of Asherman’s syndrome. The main goal of treatment in this syndrome is to repair the damaged endometrium for creating a physiological pregnancy. Objective: To investigate the effect of intrauterine injection of hyaluronic acid on the prevention of Asherman’s syndrome in women undergoing uterine septum resection. Materials and Methods: In this double-blind randomized clinical trial, 65 women undergoing the uterine septum resection were divided into two groups; the case group (n = 34) and the control group (n = 31). Immediately after the septal resection with a resectoscope, 1cc of hyaluronic acid gel in the case group and 1cc normal saline solution as a placebo in the control group was injected into the uterine cavity. After two months, existence of intrauterine adhesions in the both groups was examined by the hysteroscope and assessment of menstrual patterns, according to the American Society for Reproductive Medicine criteria. Results: Our results showed that after intervention, the incidence of Asherman’s syndrome in the control group was higher than the case group (p = 0.012). In the case group, only four women had poor adhesion (Asherman’s syndrome) at the end of the study, while the rest of them were free of any adhesions in the uterine cavity. In the control group, however, only 19 were free of intrauterine adhesions and 12 had mild symptoms. Conclusion: The results of the study exhibited the hyaluronic acid capacity to reduce the risk of Asherman’s syndrome in women with endometrial damage following a septal resection surgery. Key words: Asherman’s syndrome, Septum, Uterine, Hyaluronic acid, Resection

Representation of a ‘positive experience’ of surrogacy in Yazd, Iran: A qualitative study

Background: The social and cultural challenges facing surrogate mothers have been explored in several studies. However, few studies have discussed the motivations of surrogate mothers, their expressions and interpretations of their lived experiences, and their feelings of personal and spiritual satisfaction. Objective: This study aims to present the positive experiences of surrogate mothers from a phenomenological perspective. Materials and Methods: Using a phenomenological approach, this study was conducted from September 2020 to January 2021 in the city of Yazd, Iran. Participant observation and semi-structured interviews were used to collect the data among 12 participants with at least 1 experience of surrogate motherhood. Results: Our findings showed that, despite having had harsh physical and socio-cultural experiences such as fear of social labeling and stigma, participants felt a kind of inner satisfaction and a positive view of their actions. A core theme found in the study was mothers’ satisfaction. The main categories included feminine self-sacrifice and positive rewards. Feminine self-sacrifice included 2 sub-categories: creating happiness and conveying motherly feelings, while positive rewards included good childbirth, family acceptance, and halal income. Conclusion: This study showed that surrogate mothers experience conflicting feelings of inner satisfaction and social stigma during surrogacy. Some of those interviewed were willing to go through surrogacy again, but they feared social labeling and stigma, being misunderstood by others who are not fully informed about surrogacy, and being subjected to family and social disapproval. Key words: Surrogate mothers, Emotions, Personal satisfaction, Infertility

Dental Pulp Polyps Contain Stem Cells Comparable to the Normal Dental Pulps

Objectives: Few studies investigated the isolation of stem cells from pathologically injured dental tissues. The aim of this study was to assess the possibility of isolation of stem cells from pulp polyps (chronic hyperplastic pulpitis), a pathological tissue produced in an inflammatory proliferative response within a tooth. Study design: Pulp polyp tissues were enzymatically digested and the harvested single cells were cultured. Cultured cells underwent differentiation to adipocytes and osteoblasts as well as flowcytometric analysis for markers such as: CD90, CD73, CD105, CD45, and CD14. In addition we tried to compare other characteristics (including colonigenic efficacy, population doubling time and the cell surface antigen panels) of these cells to that of healthy dental pulp stem cells (DPSCs). Results: Cells isolated from pulp polyps displayed spindle shape morphology and differentiated into adipocytes and osteoblasts successfully. These cells expressed CD90, CD73, and CD105 while were negative for CD45, CD14. Number of colonies among 104 tissue cells was higher in the normal pulp tissue derived cells than the pulp polyps (P=0.016); but as polyp tissues are larger and contain more cells (P=0.004), the total number of the stem cell in a sample tissue was higher in polyps but not significantly (P=0.073). Conclusions: The cells isolated from pulp polyps fulfill minimal criteria needed for MSC definition; hence, it can be concluded that pulp polyps contain stem cells. Although pulp polyps are rare tissues in daily practice but when they are present, may serve as a possible new non-invasively acquired tissue resource of stem cells for affected patients. List of abbreviations: APC = allophycocyanin, BM = Bone Marrow, CFU-F = Colony Forming Unit Fibroblast, DPSC = Dental Pulp Stem Cell, FITC = fluorescein isothiocyanate, MNC = mononuclear cells, MSC = Multipotent Mesenchymal Stromal Cell, PE = Phycoerythrin, PerCP = Peridinin chlorophyll protein, PPSC = Pulp Polyp Stem Cell