Prospectus, May 4, 1970

PC TEACH-IN ON OVER POPULATION; James, Neal Propose Registration Revisions; Parking Tickets Can Cause Suspension; Applications Ready For Fall Elections; Second Road Rally Scheduled; Butler Wins Scholarship; Letters To The Editor; Political Oppression; Environmental Crisis Week: Boneyard Cleanup Has Large Turnout; What People had to say....; C-U Boneyard Shown On Slides In Quiet Lounge; Government needs to be Restructured: Malkovich; Kraft-Humko Given Thirty Days; \u27Fantasia\u27 Is Sensory Experience; College President Is Not Censor; Bull Page: Speaker Engaged For Graduation, Calendar, Second Road Rally Scheduledhttps://spark.parkland.edu/prospectus_1970/1028/thumbnail.jp

Prospectus, June 3, 1970

PARKLAND OBSERVES STRIKE; President Nixon Addresses Graduates; Kraft-Humko Report Is Vague and Insufficient ; Letters To The Editor; Repression Of Teachers; Farris Talks About Year\u27s Work, Events; White House Conference; Dental Hygiene Activities: Students Active In Community Programs; Ruth St. John: Withdraw As Fast As Possible , We Always Keep On Learning ; Students Endorse Strike; Prospectus, Senate Push Boycott; Students Speak Out On Strike; Student Strike Poll Results; Administrators Claim Parkland Not Affected By Strike; Cambodia--Another Nam?; Anti-Nixon, Cambodia Teach-In; Faculty Says Symbolic Strike Justified; Hypnosis Increasingly Popular In Medicine; Woodstock Denies Capitalism, Profit; Summer Recreation At Allerton Park; From The Office of Senator Edward M. Kennedy of Massachusetts; Bull Page: Article Appear In Agricultural Education Magazine, P.C. Students Wins State Speech Contest; Student Govt., College Draft Deferments, Teacher Aid Classes Have Lecturer; Exploding Population : Blazier Lectures On Population Problem; Hopes For Control Of Contraception; Candy Store-Restaurant Ends 45 Year Historyhttps://spark.parkland.edu/prospectus_1970/1027/thumbnail.jp

Fashion and passion: marketing sex to women

Against a backdrop of a ‘pornographication’ of mainstream media and the emergence of a more heavily sexualized culture, women are increasingly targeted as sexual consumers. In the UK, the success of TV shows like Sex and the City and the ‘fashion ‘n’ passion’ of sex emporia like Ann Summers suggests that late twentieth century discourses which foregrounded female pleasure have crystallised in a new form of sexual address to women. This article examines how sex products are being marketed for female consumers, focussing on the websites of sex businesses such as Myla, Babes n Horny, Beecourse, tabooboo and Ann Summers. It asks how a variety of existing discourses – of fashion, consumerism, bodily pleasure and sexuality - are drawn on in the construction of this new market, how they negotiate the dangers and pleasures of sexuality for women, and what they show about the construction of ‘new’ female sexualities.</p

Concert recording 2022-11-08

[Track 1]. Beau soir / Claude Debussy -- The lass from the Low Countree / John Jacob Niles – [Track 2]. Into the night / Clara Edwards -- [Track 3]. An Silvia / Franz Schubert -- [Track 4]. Se tu m’ami, se sospiri / Alessandro Parisotti -- [Track 5]. Erlafsee / Franz Schubert -- [Track 6]. Vittoria, mio core / Giacomo Carissimi -- [Track 7]. Aufenthalt / Franz Schubert -- [Track 8]. Amarilli, mia bella / Giulio Caccini -- [Track 9]. There’s a Fine, Fine Line, from Avenue Q / Robert Lopez and Jeff Marx -- [Track 10]. Go, lovely rose / Roger Quilter -- [Track 11]. Vagabond / Ralph Vaughan Williams -- [Track 12]. Sebben, crudele / Antonio Caldara -- [Track 13]. Love’s philosophy / Roger Quilter (1877–1953) -- [Track 14]. Perla gloria / Giovanni Bononcini -- [Track 15]. Money, O! / Michael Head -- [Track 16]. Lasciate mi morire / Claudio Monteverdi -- Across the western ocean / Arr. Celius Dougherty -- [Track 17]. Perduta ho la Speranza / Stefano Donaudy -- [Track 18]. Lonley House from Street Scene / Kurt Weill -- [Track 19]. Preghiera / Paolo Tosti -- [Track 20]. Allerseelen / Richard Strauss -- [Track 21]. Im wunderschönen Monat Mai / Robert Schumann -- [Track 22]. Una furtiva lagrima from L’elisir d’amore / Gaetano Donizetti -- [Track 23]. V’adoro, pupille, from Giulio Cesare / George Handel -- [Track 24]. Sympathy / Florence Price -- [Track 25]. The German U-boat captain / Gene Scheer -- [Track 26]. Eri tu che macchiavi, from Un Ballo in Maschera / Giuseppe Verdi

Concert recording 2022-11-08

[Track 1]. Beau soir / Claude Debussy -- The lass from the Low Countree / John Jacob Niles – [Track 2]. Into the night / Clara Edwards -- [Track 3]. An Silvia / Franz Schubert -- [Track 4]. Se tu m’ami, se sospiri / Alessandro Parisotti -- [Track 5]. Erlafsee / Franz Schubert -- [Track 6]. Vittoria, mio core / Giacomo Carissimi -- [Track 7]. Aufenthalt / Franz Schubert -- [Track 8]. Amarilli, mia bella / Giulio Caccini -- [Track 9]. There’s a Fine, Fine Line, from Avenue Q / Robert Lopez and Jeff Marx -- [Track 10]. Go, lovely rose / Roger Quilter -- [Track 11]. Vagabond / Ralph Vaughan Williams -- [Track 12]. Sebben, crudele / Antonio Caldara -- [Track 13]. Love’s philosophy / Roger Quilter (1877–1953) -- [Track 14]. Perla gloria / Giovanni Bononcini -- [Track 15]. Money, O! / Michael Head -- [Track 16]. Lasciate mi morire / Claudio Monteverdi -- Across the western ocean / Arr. Celius Dougherty -- [Track 17]. Perduta ho la Speranza / Stefano Donaudy -- [Track 18]. Lonley House from Street Scene / Kurt Weill -- [Track 19]. Preghiera / Paolo Tosti -- [Track 20]. Allerseelen / Richard Strauss -- [Track 21]. Im wunderschönen Monat Mai / Robert Schumann -- [Track 22]. Una furtiva lagrima from L’elisir d’amore / Gaetano Donizetti -- [Track 23]. V’adoro, pupille, from Giulio Cesare / George Handel -- [Track 24]. Sympathy / Florence Price -- [Track 25]. The German U-boat captain / Gene Scheer -- [Track 26]. Eri tu che macchiavi, from Un Ballo in Maschera / Giuseppe Verdi

THE CONCISE GUIDE TO PHARMACOLOGY 2019/20 : G protein- coupled receptors

The Concise Guide to PHARMACOLOGY 2019/20 is the fourth in this series of biennial publications. The Concise Guide provides concise overviews of the key properties of nearly 1800 human drug targets with an emphasis on selective pharmacology (where available), plus links to the open access knowledgebase source of drug targets and their ligands (www.guidetopharmacology.org), which provides more detailed views of target and ligand properties. Although the Concise Guide represents approximately 400 pages, the material presented is substantially reduced compared to information and links presented on the website. It provides a permanent, citable, point-in-time record that will survive database updates. The full contents of this section can be found at http://onlinelibrary.wiley.com/doi/10.1111/bph.14748. G protein-coupled receptors are one of the six major pharmacological targets into which the Guide is divided, with the others being: ion channels, nuclear hormone receptors, catalytic receptors, enzymes and transporters. These are presented with nomenclature guidance and summary information on the best available pharmacological tools, alongside key references and suggestions for further reading. The landscape format of the Concise Guide is designed to facilitate comparison of related targets from material contemporary to mid-2019, and supersedes data presented in the 2017/18, 2015/16 and 2013/14 Concise Guides and previous Guides to Receptors and Channels. It is produced in close conjunction with the International Union of Basic and Clinical Pharmacology Committee on Receptor Nomenclature and Drug Classification (NC-IUPHAR), therefore, providing official IUPHAR classification and nomenclature for human drug targets, where appropriate.Peer reviewe

Finishing the euchromatic sequence of the human genome

The sequence of the human genome encodes the genetic instructions for human physiology, as well as rich information about human evolution. In 2001, the International Human Genome Sequencing Consortium reported a draft sequence of the euchromatic portion of the human genome. Since then, the international collaboration has worked to convert this draft into a genome sequence with high accuracy and nearly complete coverage. Here, we report the result of this finishing process. The current genome sequence (Build 35) contains 2.85 billion nucleotides interrupted by only 341 gaps. It covers ∼99% of the euchromatic genome and is accurate to an error rate of ∼1 event per 100,000 bases. Many of the remaining euchromatic gaps are associated with segmental duplications and will require focused work with new methods. The near-complete sequence, the first for a vertebrate, greatly improves the precision of biological analyses of the human genome including studies of gene number, birth and death. Notably, the human enome seems to encode only 20,000-25,000 protein-coding genes. The genome sequence reported here should serve as a firm foundation for biomedical research in the decades ahead

Age-related immune response heterogeneity to SARS-CoV-2 vaccine BNT162b2

Abstract: Although two-dose mRNA vaccination provides excellent protection against SARS-CoV-2, there is little information about vaccine efficacy against variants of concern (VOC) in individuals above eighty years of age1. Here we analysed immune responses following vaccination with the BNT162b2 mRNA vaccine2 in elderly participants and younger healthcare workers. Serum neutralization and levels of binding IgG or IgA after the first vaccine dose were lower in older individuals, with a marked drop in participants over eighty years old. Sera from participants above eighty showed lower neutralization potency against the B.1.1.7 (Alpha), B.1.351 (Beta) and P.1. (Gamma) VOC than against the wild-type virus and were more likely to lack any neutralization against VOC following the first dose. However, following the second dose, neutralization against VOC was detectable regardless of age. The frequency of SARS-CoV-2 spike-specific memory B cells was higher in elderly responders (whose serum showed neutralization activity) than in non-responders after the first dose. Elderly participants showed a clear reduction in somatic hypermutation of class-switched cells. The production of interferon-γ and interleukin-2 by SARS-CoV-2 spike-specific T cells was lower in older participants, and both cytokines were secreted primarily by CD4 T cells. We conclude that the elderly are a high-risk population and that specific measures to boost vaccine responses in this population are warranted, particularly where variants of concern are circulating