299 research outputs found
Steerable optical tweezers for ultracold atom studies
We report on the implementation of an optical tweezer system for controlled
transport of ultracold atoms along a narrow, static confinement channel. The
tweezer system is based on high-efficiency acousto-optical deflectors and
offers two-dimensional control over beam position. This opens up the
possibility for tracking the transport channel when shuttling atomic clouds
along the guide, forestalling atom spilling. Multiple clouds can be tracked
independently by time-shared tweezer beams addressing individual sites in the
channel. The deflectors are controlled using a multichannel direct digital
synthesizer, which receives instructions on a sub-microsecond time scale from a
field-programmable gate array. Using the tweezer system, we demonstrate
sequential binary splitting of an ultracold cloud into
clouds.Comment: 4 pages, 5 figures, 1 movie lin
Core Health Outcomes In Childhood Epilepsy (CHOICE):Protocol for the selection of a core outcome set
This is the final version of the article. Available from BioMed Central via the DOI in this record.BACKGROUND: There is increasing recognition that establishing a core set of outcomes to be evaluated and reported in trials of interventions for particular conditions will improve the usefulness of health research. There is no established core outcome set for childhood epilepsy. The aim of this work is to select a core outcome set to be used in evaluative research of interventions for children with rolandic epilepsy, as an exemplar of common childhood epilepsy syndromes. METHODS: First we will identify what outcomes should be measured; then we will decide how to measure those outcomes. We will engage relevant UK charities and health professional societies as partners, and convene advisory panels for young people with epilepsy and parents of children with epilepsy. We will identify candidate outcomes from a search for trials of interventions for childhood epilepsy, statutory guidance and consultation with our advisory panels. Families, charities and health, education and neuropsychology professionals will be invited to participate in a Delphi survey following recommended practices in the development of core outcome sets. Participants will be able to recommend additional outcome domains. Over three rounds of Delphi survey participants will rate the importance of candidate outcome domains and state the rationale for their decisions. Over the three rounds we will seek consensus across and between families and health professionals on the more important outcomes. A face-to-face meeting will be convened to ratify the core outcome set. We will then review and recommend ways to measure the shortlisted outcomes using clinical assessment and/or patient-reported outcome measures. DISCUSSION: Our methodology is a proportionate and pragmatic approach to expediently produce a core outcome set for evaluative research of interventions aiming to improve the health of children with epilepsy. A number of decisions have to be made when designing a study to develop a core outcome set including defining the scope, choosing which stakeholders to engage, most effective ways to elicit their views, especially children and a potential role for qualitative research.This study is part of Changing Agendas on Sleep, Treatment and Learning in Childhood Epilepsy (CASTLE), which is funded by the National Institute for Health Research (NIHR) Programme Grants for Applied Research RP-PG-0615-20007
Equivalence of the First-Order Target-Continuum Distorted-Wave and a Simplified form of the Second-Order Faddeev-Watson Approximations
Ultracold atom superfluidity induced by the Feshbach resonance
We discuss the possible signatures of superfluidity induced by the Feshbach
resonance in ultracold gas of fermion atoms. Approaching the phase transition
from above there appear various manifestations of the gradually emerging order
parameter, but yet the long range coherence is not established due to strong
quantum fluctuations. The single particle excitation spectrum becomes gapped
while at the same time the pair excitations are characterized by the narrow
quasiparticle peak surrounded by the incoherent background. This quasiparticle
shows up certain collective features such as the remnant of the "first sound"
which at Tc spreads down to low momenta. Presence of this Goldstone mode is the
most unambiguous proof for appearance of the superfluid state. We discuss how
such mode can be detected experimentally.Comment: 5 pages, 3 figure
Core Health Outcomes in Childhood Epilepsy (CHOICE): Development of a core outcome set using systematic review methods and a Delphi survey consensus.
This is the final version. Available from the publisher via the DOI in this record.OBJECTIVE: Establishing a core set of outcomes to be evaluated and reported in intervention trials aims to improve the usefulness of health research. There is no established core outcome set (COS) for childhood epilepsies. The aim of this study was to select a COS to be used in evaluative research of interventions for children with rolandic epilepsy (RE). METHODS: We followed guidance from the COMET (Core Outcome Measures in Effectiveness Trials) Initiative. First, we identified outcomes that had been measured in research through a systematic review. Second, young people with RE, parents, and professionals were invited to take part in a Delphi survey in which participants rated the importance of candidate outcomes. Last, a face-to-face meeting was convened to seek consensus on which outcomes were critical to include and to ratify the final COS. RESULTS: From 37 eligible papers in the review, we identified and included 48 candidate outcomes in the survey. We sent invitations to 165 people registered to take part in the survey; of these, 102 (62%) completed Round 1, and 80 (78%) completed Round 2 (three young people, 16 parents, 61 professionals). In Round 2 we included four additional outcomes suggested by participants in Round 1. The consensus meeting included two young people, four parents, and nine professionals who were eligible to vote and ratified the COS as 39 outcomes across 10 domains. SIGNIFICANCE: Our methodology was a proportionate and pragmatic approach toward producing a COS for evaluating research on interventions aiming to improve the health of children with RE.National Institute for Health Research (NIHR
The impact of parent treatment preference and other factors on recruitment: lessons learned from a paediatric epilepsy randomised controlled trial
Scenario of Accelerating Universe from the Phenomenological \Lambda- Models
Dark matter, the major component of the matter content of the Universe,
played a significant role at early stages during structure formation. But at
present the Universe is dark energy dominated as well as accelerating. Here,
the presence of dark energy has been established by including a time-dependent
term in the Einstein's field equations. This model is compatible with
the idea of an accelerating Universe so far as the value of the deceleration
parameter is concerned. Possibility of a change in sign of the deceleration
parameter is also discussed. The impact of considering the speed of light as
variable in the field equations has also been investigated by using a well
known time-dependent model.Comment: Latex, 9 pages, Major change
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