Creating Digital Culture by digitizing CulturalHeritage: the Crowddreaming living lab method

This paper1 outlines the current progress in the development of an innovative living labmethodology named The Art of Crowddreaming. The Stati Generali dell’Innovazione (SGI)together with the Digital Cultural Heritage, Arts & Humanities School (DiCultHer) – aninterdisciplinary network of over 70 Italian organizations including universities, researchentities, cultural institutions and associations – has designed and defined such methodologysince 2016, testing models to build soft skills required to co-create, manage, preserve andsafeguard digital cultural heritage. The methodology has been proven to be able to engageinnovators, researchers, youth of schools of any grade and other societal actors as a communityin the challenge to invent, co-design and build prototypes of cross-generational digital culturalheritage applying the innovative Digital CulturalMonuments process. The experimentation ofthe methodology is illustrated by means of two case studies of Museater collaborative creation.Quintana 4D engaged students of schools of any grade in the City of Foligno in an trans-disciplinary effort to design, expand and manage the Museater of the Joust of Quintana.Heritellers engaged students of “F. De Sanctis” high school for classical studies in the City ofTrani in the making of "CastleTrApp", a digital storytelling app and a Museater performanceabout the famous Swabian Castle of their City

Strategie di documentazione per la ricerca e la comunicazione archeologica. Il caso di Faragola (Foggia, Italia)

[ES] La tecnología nos ha permitido reflexionar sobre el proceso de documentación arqueológica mediante la introducción de importantes innovaciones en todas las fases de la investigación, de recuperación de datos para el análisis, la interpretación, la reconstrucción y la comunicación de los resultados. Hoy en día los equipos arqueológicos tienen acceso directo a las nuevas herramientas y métodos en el sitio, pero a menudo sin un objetivo claro y preciso; sin ninguna pretensión de presentar un modelo, el presente documento describe una serie de experimentos de campo, y reflexiones sobre la base de la creciente utilización de computadoras en las diferentes fases de nuestra investigación.[EN] Computer technology has allowed us to rethink the process of archaeological documentation by introducing important innovations in all phases of research, from recovery of data to analysis, interpretation, reconstruction and communication of results. Nowadays archaeological teams have direct access to new tools and methods on site, but often without a clear and precise purpose; the methodological chaos that reigns over the application of computer technology to the practice of archaeology is clearly visible. Without any pretense of presenting a model, this paper describes a series of field experiments conducted on Faragola site, and reflections based on the growing use of computers in the various phases of our researchDe Felice, G.; Sibilano, MG. (2010). Strategie di documentazione per la ricerca e la comunicazione archeologica. Il caso di Faragola (Foggia, Italia). Virtual Archaeology Review. 1(2):95-99. https://doi.org/10.4995/var.2010.4696OJS959912BARCELÒ J. A. (2000): "Visualizing what might be. An introduction to Virtual Reality techniques in archaeology", in BARCELÒ J. A., FORTE M., SANDERS D. H. (eds.) Virtual Reality in Archaeology, Oxford, pp. 9-35.BARCELÒ, J. A. (2001): "Virtual reality for archaeological explanation. Beyond "picturesque reconstruction", in Archeologia e Calcolatori, 12, pp. 221-244.BARCELÒ, J. A., DE CASTRO, O., TRAVET, D., VICENTE, O. (2003): "A 3D model of an archaeological excavation", in DOERR M., SARRIS A. (eds.) The digital heritage of archaeology, Proceedings of the 30th CAA conference (Heraklion, Crete, April 2002), Heraklion, pp. 85-89.CARVER, M. O. H. (1990): "Digging for data: archaeological approaches to data definition, acquisition and analysis", in FRANCOVICH R., MANACORDA D. (eds.): Lo scavo archeologico. Dalla diagnosi all'edizione, III Ciclo di lezioni sulla ricerca applicata in archeologia, Certosa di Pontignano (Siena, 6-18 novembre 1989), Firenze, pp. 45-120.D'ANDREA, A. (2006): Documentazione archeologica, standard e trattamento informatico, Budapest.DE FELICE, G. (2008): "Il progetto Itinera. Ricerca e comunicazione attraverso nuovi metodi di documentazione archeologica" in DE FELICE G., SIBILANO. G., VOLPE G. (eds.) L'informatica e il metodo della stratigrafia. Atti del Workshop Digitalizzare la pesantezza (Foggia 6-7 giugno 2008), Bari, pp. 13-24.DE FELICE, G., SIBILANO, G., VOLPE, G. (2008): "Ripensare la documentazione archeologica: nuovi percorsi per la ricerca e la comunicazione", in Archeologia e Calcolatori, 19, in press.DE FELICE, G., MANGIALARDI, N., SIBILANO, G., VOLPE, G. (2008): "Late Roman Villa at Faragola (Foggia, Italy). Laser scanner for a global documentation methodology during field research", in POSLUSCHNY A., LAMBERS K., HERZOG I. (eds.) Layers of perception, Proceedings of the 35th CAA conference (Berlin, April 2007), Bonn, on cd-rom.Forte M. (ed.) (2007): La villa di Livia, Un percorso di ricerca di archeologia virtuale, Roma.LOCK, G. (2003): Using computers in archaeology: towards virtual pasts, London-New York.MANACORDA, D. (2004): Prima lezione di archeologia, Roma-Bari.MANACORDA, D. (2008): Lezioni di archeologia, Roma-Bari.MEDRI, M. (2003): Manuale di rilievo archeologico, Roma-Bari.RYAN, N. (2001): "Documenting and validating virtual archaeology", in Archeologia e calcolatori, 12, pp. 245-273.SIBILANO, M. G. (2008): "Documentare lo scavo archeologico: nuove forme di comunicazione del metodo stratigrafico", in DE FELICE G., SIBILANO. G., VOLPE G. (eds.) L'informatica e il metodo della stratigrafia. Atti del Workshop Digitalizzare la pesantezza (Foggia 6-7 giugno 2008), Bari, 143-158.VOLPE, G. (2007): "L'archeologia "globale" per ascoltare la "storia totale" del paesaggio", in Sudest, 20, pp. 20-32.VOLPE, G., DE FELICE, G., TURCHIANO, M. (2005): "Faragola (Ascoli Satriano). Una residenza aristocratica tardoantica e un villaggio altomedievale nella Valle del Carapelle: primi dati", in VOLPE, G., TURCHIANO, M. (eds.), Paesaggi e insediamenti rurali in Italia meridionale fra Tardoantico e Altomedioevo. Atti del I Seminario sul Tardoantico e l'Altomedioevo in Italia meridionale (STAIM 1) (Foggia, 12-14 febbraio 2004), Bari, pp. 265-297.VOLPE, G., DE FELICE, G., TURCHIANO, M. 2006, "La villa tardoantica di Faragola (Ascoli Satriano) in Apulia", in ARCE, J., BROGIOLO, G. P., CHAVARRIA, A. (eds.): Villas tardoantiguas en el Occidente mediterraneo, in Anejos de Archivio Espanol de Arquelogia, XXXIX, Madrid, pp. 221-251

Risk factors associated with adverse fetal outcomes in pregnancies affected by Coronavirus disease 2019 (COVID-19): a secondary analysis of the WAPM study on COVID-19.

Objectives To evaluate the strength of association between maternal and pregnancy characteristics and the risk of adverse perinatal outcomes in pregnancies with laboratory confirmed COVID-19. Methods Secondary analysis of a multinational, cohort study on all consecutive pregnant women with laboratory-confirmed COVID-19 from February 1, 2020 to April 30, 2020 from 73 centers from 22 different countries. A confirmed case of COVID-19 was defined as a positive result on real-time reverse-transcriptase-polymerase-chain-reaction (RT-PCR) assay of nasal and pharyngeal swab specimens. The primary outcome was a composite adverse fetal outcome, defined as the presence of either abortion (pregnancy loss before 22 weeks of gestations), stillbirth (intrauterine fetal death after 22 weeks of gestation), neonatal death (death of a live-born infant within the first 28 days of life), and perinatal death (either stillbirth or neonatal death). Logistic regression analysis was performed to evaluate parameters independently associated with the primary outcome. Logistic regression was reported as odds ratio (OR) with 95% confidence interval (CI). Results Mean gestational age at diagnosis was 30.6+/-9.5 weeks, with 8.0% of women being diagnosed in the first, 22.2% in the second and 69.8% in the third trimester of pregnancy. There were six miscarriage (2.3%), six intrauterine device (IUD) (2.3) and 5 (2.0%) neonatal deaths, with an overall rate of perinatal death of 4.2% (11/265), thus resulting into 17 cases experiencing and 226 not experiencing composite adverse fetal outcome. Neither stillbirths nor neonatal deaths had congenital anomalies found at antenatal or postnatal evaluation. Furthermore, none of the cases experiencing IUD had signs of impending demise at arterial or venous Doppler. Neonatal deaths were all considered as prematurity-related adverse events. Of the 250 live-born neonates, one (0.4%) was found positive at RT-PCR pharyngeal swabs performed after delivery. The mother was tested positive during the third trimester of pregnancy. The newborn was asymptomatic and had negative RT-PCR test after 14 days of life. At logistic regression analysis, gestational age at diagnosis (OR: 0.85, 95% CI 0.8-0.9 per week increase; pPeer reviewe

Goodbye Hartmann trial: a prospective, international, multicenter, observational study on the current use of a surgical procedure developed a century ago

Background: Literature suggests colonic resection and primary anastomosis (RPA) instead of Hartmann's procedure (HP) for the treatment of left-sided colonic emergencies. We aim to evaluate the surgical options globally used to treat patients with acute left-sided colonic emergencies and the factors that leading to the choice of treatment, comparing HP and RPA. Methods: This is a prospective, international, multicenter, observational study registered on ClinicalTrials.gov. A total 1215 patients with left-sided colonic emergencies who required surgery were included from 204 centers during the period of March 1, 2020, to May 31, 2020. with a 1-year follow-up. Results: 564 patients (43.1%) were females. The mean age was 65.9 ± 15.6 years. HP was performed in 697 (57.3%) patients and RPA in 384 (31.6%) cases. Complicated acute diverticulitis was the most common cause of left-sided colonic emergencies (40.2%), followed by colorectal malignancy (36.6%). Severe complications (Clavien-Dindo ≥ 3b) were higher in the HP group (P < 0.001). 30-day mortality was higher in HP patients (13.7%), especially in case of bowel perforation and diffused peritonitis. 1-year follow-up showed no differences on ostomy reversal rate between HP and RPA. (P = 0.127). A backward likelihood logistic regression model showed that RPA was preferred in younger patients, having low ASA score (≤ 3), in case of large bowel obstruction, absence of colonic ischemia, longer time from admission to surgery, operating early at the day working hours, by a surgeon who performed more than 50 colorectal resections. Conclusions: After 100 years since the first Hartmann's procedure, HP remains the most common treatment for left-sided colorectal emergencies. Treatment's choice depends on patient characteristics, the time of surgery and the experience of the surgeon. RPA should be considered as the gold standard for surgery, with HP being an exception

Infected pancreatic necrosis: outcomes and clinical predictors of mortality. A post hoc analysis of the MANCTRA-1 international study

: The identification of high-risk patients in the early stages of infected pancreatic necrosis (IPN) is critical, because it could help the clinicians to adopt more effective management strategies. We conducted a post hoc analysis of the MANCTRA-1 international study to assess the association between clinical risk factors and mortality among adult patients with IPN. Univariable and multivariable logistic regression models were used to identify prognostic factors of mortality. We identified 247 consecutive patients with IPN hospitalised between January 2019 and December 2020. History of uncontrolled arterial hypertension (p = 0.032; 95% CI 1.135-15.882; aOR 4.245), qSOFA (p = 0.005; 95% CI 1.359-5.879; aOR 2.828), renal failure (p = 0.022; 95% CI 1.138-5.442; aOR 2.489), and haemodynamic failure (p = 0.018; 95% CI 1.184-5.978; aOR 2.661), were identified as independent predictors of mortality in IPN patients. Cholangitis (p = 0.003; 95% CI 1.598-9.930; aOR 3.983), abdominal compartment syndrome (p = 0.032; 95% CI 1.090-6.967; aOR 2.735), and gastrointestinal/intra-abdominal bleeding (p = 0.009; 95% CI 1.286-5.712; aOR 2.710) were independently associated with the risk of mortality. Upfront open surgical necrosectomy was strongly associated with the risk of mortality (p < 0.001; 95% CI 1.912-7.442; aOR 3.772), whereas endoscopic drainage of pancreatic necrosis (p = 0.018; 95% CI 0.138-0.834; aOR 0.339) and enteral nutrition (p = 0.003; 95% CI 0.143-0.716; aOR 0.320) were found as protective factors. Organ failure, acute cholangitis, and upfront open surgical necrosectomy were the most significant predictors of mortality. Our study confirmed that, even in a subgroup of particularly ill patients such as those with IPN, upfront open surgery should be avoided as much as possible. Study protocol registered in ClinicalTrials.Gov (I.D. Number NCT04747990)