In vitro efficacy of essential oils against Haematobia irritans

The horn fly (Haematobia irritans) infestation in the cattle in Brazil leads to significant economic damage for livestock. The efficacy of many essential oils has been demonstrated in the control of veterinary ectoparasites. This study aimed to evaluate the in vitro efficacy of four essential oils to adult horn fly control. The essential oil from Mesosphaerum suaveolens (L.) Kuntze (Lamiaceae) was extracted by hydro-distillation, while that the water steam distillation method was used to extract the essential oils from Varronia curassavica (Jacq.) Roem. & Schult. (Boraginaceae), Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. (Zingiberaceae) and Psidium guajava L. (Myrtaceae). Afterwards, all the essential oils were analyzed by Gas Chromatography Mass Spectrometry (GC?MS) and Flame Ionization Detector (GC-FID) for determination of their chemical composition. The bioassays in vitro were performed according to the impregnated filter paper methodology. All the essential oils evaluated in this study exhibited efficacy in vitro against H. irritans. The highest mortality of H. irritans was determined by essential oils from A. zerumbet (100%) and M. suaveolens (96.2%) at 50 mg mL-1.  In concentration of 100 mg mL-1 V. curassavica and P. guajava essential oils caused the mortality of 99.2% and 82.8%, respectively. The A. zerumbet, M. suaveolens, V. curassavica and P. guajava essential oils showed in vitro efficacy against H. irritans. Further studies with associations and nanoemultions are necessary to increase the efficacy and stability of these essential oils on field conditions.The horn fly (Haematobia irritans) infestation in the cattle in Brazil leads to significant economic damage for livestock. The efficacy of many essential oils has been demonstrated in the control of veterinary ectoparasites. This study aimed to evaluate the in vitro efficacy of four essential oils to adult horn fly control. The essential oil from Mesosphaerum suaveolens (L.) Kuntze (Lamiaceae) was extracted by hydro-distillation, while that the water steam distillation method was used to extract the essential oils from Varronia curassavica (Jacq.) Roem. & Schult. (Boraginaceae), Alpinia zerumbet (Pers.) B.L. Burtt & R.M. Sm. (Zingiberaceae) and Psidium guajava L. (Myrtaceae). Afterwards, all the essential oils were analyzed by Gas Chromatography Mass Spectrometry (GC?MS) and Flame Ionization Detector (GC-FID) for determination of their chemical composition. The bioassays in vitro were performed according to the impregnated filter paper methodology. All the essential oils evaluated in this study exhibited efficacy in vitro against H. irritans. The highest mortality of H. irritans was determined by essential oils from A. zerumbet (100%) and M. suaveolens (96.2%) at 50 mg mL-1. In concentration of 100 mg mL-1 V. curassavica and P. guajava essential oils caused the mortality of 99.2% and 82.8%, respectively. The A. zerumbet, M. suaveolens, V. curassavica and P. guajava essential oils showed in vitro efficacy against H. irritans. Further studies with associations and nanoemulsions are necessary to increase the efficacy and stability of these essential oils on field conditions

Discrimination and quality of life of brazilian female immigrants in Portugal

The aim of this study was to analyze the influence of discrimination perception in the quality of life and mental and physical health of Brazilian women living in Portugal, drawing on a descriptive research with a quantitative approach, with 682 female immigrants. Data collection was carried out in two modalities: online, using the LimeSurvey Platform; and presential, conducted at the Associação Mais Brasil [Association More Brazil] and at the Consulate-General of Brazil in Porto and Lisbon, with the application of the Perception of Discrimination Scale and the Medical Outcomes Study 36 – Item Short – Form Health Survey (SF -36). A significant negative correlation was observed between most SF-36 items and the Perception of Discrimination Scale, demonstrating an inversely proportional relation when respondents reporting a higher level of discrimination presented a lower quality of life. Results demonstrate the presence of a strong perception of discrimination, turning it into one of the greatest problems faced by immigrants. Among the most significantly affected dimensions, the following aspects stand out: emotional, pain, overall health status, vitality, social aspects, perception of discrimination, and health changes through time. The exception lies in the functional capacity dimension, which does not present a significant relation with the Perception of Discrimination Scale. The outcomes highlight the negative impact of perceived discrimination on the quality of life dimensions, engendering harmful effects, as well as on physical and mental health. The study points out the need to create public policies that seek to receive, include and integrate female immigrants, guaranteeing their rights and providing information on their duties, in order to reduce discrimination and improve the quality of life and health of this population.info:eu-repo/semantics/publishedVersio

Horizontal Alveolar Ridge Augmentation in the Mandibular Posterior Region Using Biphasic Calcium Phosphate and Leukocyte- and Platelet rich fibrin (L-PRF): A case report.

In bone defects caused by tooth loss, tissue reconstructions are necessary to enable prosthetic rehabilitation with dental implants. Diverse techniques and materials of different origins are used for this purpose.  Leukocyte- and Platelet-Rich Fibrin (L-PRF) has been used in association with osteoconductive biomaterials in procedures of bone regeneration and for covering grafted areas. The aim of this article was to demonstrate a clinical case of bone grafting in the posterior region of the mandible, performed with the use of synthetic biomaterial composed of biphasic calcium phosphate associated with Leukocyte- and Platelet-Rich Fibrin for performing bone augmentation in an alveolar ridge with a horizontal defect, thereby enabling later installation of dental implants and prosthetic rehabilitation in the region. Keywords: bone graft, biomaterials, leukocyte- and platelet-rich fibrin, bone substitutes, dental implants.In bone defects caused by tooth loss, tissue reconstructions are necessary to enable prosthetic rehabilitation with dental implants. Diverse techniques and materials of different origins are used for this purpose.  Leukocyte- and Platelet-Rich Fibrin (L-PRF) has been used in association with osteoconductive biomaterials in procedures of bone regeneration and for covering grafted areas. The aim of this article was to demonstrate a clinical case of bone grafting in the posterior region of the mandible, performed with the use of synthetic biomaterial composed of biphasic calcium phosphate associated with Leukocyte- and Platelet-Rich Fibrin for performing bone augmentation in an alveolar ridge with a horizontal defect, thereby enabling later installation of dental implants and prosthetic rehabilitation in the region.

Novel rearrangements between different chromosomes with direct impact on the diagnosis of 5p- syndrome

Objectives: Copy Number Variations (CNVs) in the human genome account for common populational variations but can also be responsible for genetic syndromes depending on the affected region. Although a deletion in 5p is responsible for a syndrome with highly recognizable phenotypical features, other chromosomal abnormalities might overlap phenotypes, especially considering that most studies in 5p use traditional cytogenetic techniques and not molecular techniques. Methods: The authors have investigated 29 patients with clinical suspicion of 5p- syndrome using Chromosomal Microarray (CMA), and have gathered information on previous tests, clinical signs, symptoms, and development of the patients. Results: The results showed 23 pure terminal deletions, one interstitial deletion, one deletion followed by a 3 Mb duplication in 5p, three cases of 5p deletion concomitant to duplications larger than 20 Mb in chromosomes 2, 9, and 18, and one 5p deletion with a chromosome Y deletion. CMA showed relevant CNVs not typically associated with 5p- that may have contributed to the final phenotype in these patients. Conclusions: The authors have identified three novel rearrangements between chromosomes 5 and 2 (Patient 27), 5 and 18 (Patient 11), and 5 and Y (Patient 22), with breakpoints and overlapped phenotypes that were not previously described. The authors also highlight the need for further molecular investigation using CMA, in different chromosomes beyond chromosome 5 (since those cases did not show only the typical deletion expected for the 5p- syndrome) to explain discordant chromosomal features and overlapped phenotypes to unravel the cause of the syndrome in atypical cases

Chemical composition and antioxidant potential of essential oils from different Ocimum species (Basil) / Composição química e atividade antioxidante de óleos essenciais de diferentes espécies de Ocimum (Manjericão)

Plants of the genus Ocimum are widely used in cooking, cosmetics and folk medicine, mainly antibacterial, antifungal and antioxidant properties. This article examines the chemical composition and antioxidant capacity of essential oils of Ocimum varieties. The chemical composition was analyzed by gas chromatography/mass spectrometry (GC/MS). For the evaluation of the antioxidant capacities, three different methods were used: the 2,20-diphenyl-1-picrylhydrazyl radical scavenging method (DPPH), ABTS (2,2?-azinobis-(3-ethylbenzothiazoline-6-sulfonic acid)) antiradical method and ?-carotene/peroxyl radicals (LOO•) systems. There was a great variability in the composition and some species had a high eugenol content: O. tenuiflorum>O. campechianum>O. basilicum var. ball>O. gratissimum >O. basilicum var. greek. Methyl chavicol, neral and geranial were components found in other Ocimum species. Better antioxidant efficiency was found in species with a higher eugenol content as Ocimum tenuiflorum by DPPH IC50 2.31±0.02 µg.mL-1, ABTS IC50 2.22±0.23 µg.mL-1 and ?-carotene/linolenic acid system IC50 16.11±3.59 µg.mL-1, equally statistically significant when compared to pure eugenol. Basil essential oils had higher eugenol content in five species with strong antioxidant potential, adding a differential value to the Food Industry in the production of new functional foods or biofilms for foods with functionalities of preservation or control of chronic diseases

Guide2Blind: Sistema Háptico-Sonoro de Orientação para deficientes visuais em ambientes fechados - Fase 2 / Guide2Blind: Haptic-Sound Guidance System for the Visually Impaired Indoors - Phase 2

Este projeto tem como objetivo a construção de um sistema háptico-sonoro para o auxílio da navegação e locomoção de deficientes visuais em ambientes fechados (indoor). Os objetivos específicos são listados como: Desenvolver um dispositivo de segurança compacto para a detecção de obstáculo que efetue uma resposta de desvio rápida e nítida; desenvolver um aplicativo de detecção de potências de Wi-Fi; criar um sistema simples e rápido de mapeamento para qualquer ambiente fechado; desenvolver um algoritmo de rotas para locais mapeados; efetuar simulação de mapeamento Wi-Fi e Geolocalização. A visão é o sentido que permite o maior fluxo de informações interpretativas, e a perda desse sentido gera grande barreira para a autonomia dessas pessoas em muitas atividades, como na locomoção. Segundo o censo de 2010 do IBGE cerca de 16,6 milhões de pessoas possuam algum grau de deficiência visual, e, deste total, 506 mil sejam completamente cegos, é uma grande barreira para aos portadores da deficiência visual encontrar métodos que os auxiliem. Como uma alternativa desses métodos, o grupo propõe a construção de um sistema e idealiza: utilizar sensores e micromotores elétricos de vibração, para detectar e alertar o sentido de objetos durante a locomoção entre as rotas, possibilitando que usuário desvie de empecilhos que podem variar, em paralelo, a utilização de um aplicativo Android que utilizará de sinais de roteadores Wi-Fi, para auxiliar o usuário em sua Geolocalização através da trilateração, guiando-o até um destino escolhido e permitindo a navegação dentro das áreas previamente mapeadas.

Factors Associated with Emotion Regulation in Men with Internet Access Living in Brazil during the COVID-19 Pandemic

Publisher Copyright: © 2022 by the authors. Licensee MDPI, Basel, Switzerland.Objective: to evaluate the factors associated with emotion regulation in men with internet access living in Brazil during the COVID-19 pandemic. Method: an epidemiological survey, conducted with 1015 men. An electronic form was applied containing sociodemographic and occu-pational characteristics, support and coping strategies, as well as emotional and behavioral aspects. Emotion regulation was assessed using the Emotion Regulation Questionnaire. Results: The prevalence values observed were 44.6% for Low Cognitive Reappraisal and of 47.1% for High Emotional Sup-pression. The following factors were identified as associated: (a) with Low Cognitive Reappraisal: being aged 30 years old or more, practicing physical activity, worrying about social distancing and having positive emotions and feelings; and (b) with High Emotional Suppression: being heterosexual, non-white race/skin color, having security support or public administration, not sanitizing food, worrying about lack of physical activity and not having negative emotions. Conclusion: the adoption of emotion regulation strategies was associated with individual, contextual and emotional/behavioral characteristics. Masculinity ideals seem to exert an influence on these relationships.publishersversionpublishe

POÉTICAS DO ISOLAMENTO

Esta obra é composta por textos de um grupo de professores, que no ano de 2020, reinventaram-se em suas ações pedagógicas, buscando por meio da extensão dar continuidade ao ensino com a comunidade acadêmica e externa. O momento de distanciamento, em função da pandemia do Coronavírus, nos levou a busca de meios que possibilitassem o desenvolvimento das ações pedagógicas a distância. Então, iniciamos o processo de ampliar o nosso repertório digital para aplicá-lo no desenvolvimento das aprendizagens propostas por meio de minicursos, seminários, palestras e performances artísticas

Síndrome do coração Pós-feriado: pacientes acometidos por arritmia cardíaca em detrimento do consumo exagerado de álcool: Post Holiday coração Syndrome: patients suffered by cardiac arrhythmia to the detriment of exaggerated alcohol consumption

INTRODUÇÃO: O álcool é conhecido por beneficiar o sistema cardiovascular com a ativação do sistema fibrinolítico, redução da agregação de plaquetas e aperfeiçoamento do perfil lipídico, entre outros mecanismos, quando consumido em doses moderadas. Todavia, seu uso de maneira abusiva culmina em patologias graves que podem evoluir para a morte, como a hipertensão arterial, a cardiomiopatia alcoólica, a arritmia cardíaca e até a “Síndrome do Coração Pós Feriado” ou do inglês, “Holiday Heart Syndrome”. OBJETIVOS: O presente estudo tem como objetivo delinear sobre a Síndrome do Coração Pós Feriado, transpassando por suas características clínicas, repercussões eletrofisiológicas, diagnóstico e manejo terapêutico. MATERIAIS E MÉTODOS: Dessa forma, o presente trabalho realizou uma revisão sistemática qualitativa, realizado no período entre julho e agosto de 2022, através de artigos das bases de dados Biblioteca Virtual em Saúde (BVS) e United States National Library of Medicine (PubMed). RESULTADOS E DISCUSSÃO: A interação do álcool no organismo está diretamente relacionada com o sistema nervoso autônomo do indivíduo, gerando um estado de desequilíbrio autonômico, assim há alterações elétricas, como acréscimo da frequência cardíaca, gerando um estado de taquicardia. A principal patologia encontrada em questão foi a taquicardia sinusal, sendo um tipo de arritmia e por conseguinte, notou-se a presença da fibrilação atrial, sendo o excesso no consumo de etanol é causador de aproximadamente 67% dos casos de emergências desta última enfermidade. CONCLUSÃO: Portanto, com base na literatura analisada, observou-se que a ingestão alcoólica aguda age retardando o sistema de condução cardíaco, atua no encurtamento do período refratário e o aumento da atividade simpática, além de aumentar os níveis de catecolaminas circulantes. Por fim, também se evidenciou uma associação entre álcool e fatores de risco, principalmente hipertensão e obesidade e essas patologias aumentam os episódios de fibrilação atrial