15,510 research outputs found

    Views from the Ohio manufacturing index

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    An introduction to the experimental Ohio Manufacturing Index and a brief examination of the recent patterns of manufacturing growth occurring in the state.Manufactures - Ohio ; Ohio ; Economic indicators - Ohio

    Manufacturing checkout of orbital operational stages Midterm report, period ending 24 Feb. 1965

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    Manufacturing checkout of orbital operational Saturn S-IVB stage and instrument unit for parking orbit operation

    User benefits and funding strategies

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    The justification, economic and technological benefits of NASA Space Programs (aside from pure scientific objectives), in improving the quality of life in the United States is discussed and outlined. Specifically, a three-step, systematic method is described for selecting relevant and highly beneficial payloads and instruments for the Interim Upper Stage (IUS) that will be used with the space shuttle until the space tug becomes available. Viable Government and private industry cost-sharing strategies which would maximize the number of IUS payloads, and the benefits obtainable under a limited NASA budget were also determined. Charts are shown which list the payload instruments, and their relevance in contributing to such areas as earth resources management, agriculture, weather forecasting, and many others

    The Arecibo L-band Feed Array Zone of Avoidance Survey I: Precursor Observations through the Inner and Outer Galaxy

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    The Arecibo L-band Feed Array (ALFA) is being used to conduct a low-Galactic latitude survey, to map the distribution of galaxies and large-scale structures behind the Milky Way through detection of galaxies' neutral hydrogen (HI) 21-cm emission. This Zone of Avoidance (ZOA) survey finds new HI galaxies which lie hidden behind the Milky Way, and also provides redshifts for partially-obscured galaxies known at other wavelengths. Before the commencement of the full survey, two low-latitude precursor regions were observed, totalling 138 square degrees, with 72 HI galaxies detected. Detections through the inner Galaxy generally have no cataloged counterparts in any other waveband, due to the heavy extinction and stellar confusion. Detections through the outer Galaxy are more likely to have 2MASS counterparts. We present the results of these precursor observations, including a catalog of the detected galaxies, with their HI parameters. The survey sensitivity is well described by a flux- and linewidth-dependent signal-to-noise ratio of 6.5. ALFA ZOA galaxies which also have HI measurements in the literature show good agreement between our measurements and previous work. The inner Galaxy precursor region was chosen to overlap the HI Parkes Zone of Avoidance Survey so ALFA performance could be quickly assessed. The outer Galaxy precursor region lies north of the Parkes sky. Low-latitude large-scale structure in this region is revealed, including an overdensity of galaxies near l = 183 deg and between 5000 - 6000 km/s in the ZOA. The full ALFA ZOA survey will be conducted in two phases: a shallow survey using the observing techniques of the precursor observations, and also a deep phase with much longer integration time, with thousands of galaxies predicted for the final catalog.Comment: 26 pages, 7 figures, 2 tables, Astronomical Journal accepte

    Branching Transition of a Directed Polymer in Random Medium

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    A directed polymer is allowed to branch, with configurations determined by global energy optimization and disorder. A finite size scaling analysis in 2D shows that, if disorder makes branching more and more favorable, a critical transition occurs from the linear scaling regime first studied by Huse and Henley [Phys. Rev. Lett. 54, 2708 (1985)] to a fully branched, compact one. At criticality clear evidence is obtained that the polymer branches at all scales with dimension dˉc{\bar d}_c and roughness exponent ζc\zeta_c satisfying (dˉc1)/ζc=0.13±0.01({\bar d}_c-1)/\zeta_c = 0.13\pm 0.01, and energy fluctuation exponent ωc=0.26±0.02\omega_c=0.26 \pm0.02, in terms of longitudinal distanceComment: REVTEX, 4 pages, 3 encapsulated eps figure

    Two new ultracool benchmark systems from WISE+2MASS

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    We have used the Two-Micron All-Sky Survey and the Wide-field Infrared Survey Explorer to look for ultracool dwarfs that are part of multiple systems containing main-sequence stars. We cross-matched L dwarf candidates from the surveys with Hipparcos and Gliese stars, finding two new systems. The first system, G255-34AB, is an L2 dwarf companion to a K8 star, at a distance of 36 pc. We estimate its bolometric luminosity as log L/L-circle dot = -3.78 +/- 0.045 and T-eff = 2080 +/- 260 K. The second system, GJ499ABC, is a triple, with an L5 dwarf as a companion to a binary with an M4 and K5 star. These two new systems bring the number of L dwarf plus main-sequence star multiple systems to 24, which we discuss. We consider the binary fraction for L dwarfs and main-sequence stars, and further assess possible unresolved multiplicity within the full companion sample. This analysis shows that some of the L dwarfs in this sample might actually be unresolved binaries themselves, since their M-J appears to be brighter than the expected for their spectral types.Peer reviewe

    Recursive internetwork architecture, investigating RINA as an alternative to TCP/IP (IRATI)

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    Driven by the requirements of the emerging applications and networks, the Internet has become an architectural patchwork of growing complexity which strains to cope with the changes. Moore’s law prevented us from recognising that the problem does not hide in the high demands of today’s applications but lies in the flaws of the Internet’s original design. The Internet needs to move beyond TCP/IP to prosper in the long term, TCP/IP has outlived its usefulness. The Recursive InterNetwork Architecture (RINA) is a new Internetwork architecture whose fundamental principle is that networking is only interprocess communication (IPC). RINA reconstructs the overall structure of the Internet, forming a model that comprises a single repeating layer, the DIF (Distributed IPC Facility), which is the minimal set of components required to allow distributed IPC between application processes. RINA supports inherently and without the need of extra mechanisms mobility, multi-homing and Quality of Service, provides a secure and configurable environment, motivates for a more competitive marketplace and allows for a seamless adoption. RINA is the best choice for the next generation networks due to its sound theory, simplicity and the features it enables. IRATI’s goal is to achieve further exploration of this new architecture. IRATI will advance the state of the art of RINA towards an architecture reference model and specifcations that are closer to enable implementations deployable in production scenarios. The design and implemention of a RINA prototype on top of Ethernet will permit the experimentation and evaluation of RINA in comparison to TCP/IP. IRATI will use the OFELIA testbed to carry on its experimental activities. Both projects will benefit from the collaboration. IRATI will gain access to a large-scale testbed with a controlled network while OFELIA will get a unique use-case to validate the facility: experimentation of a non-IP based Internet

    Phosphonopeptides Revisited, in an Era of Increasing Antimicrobial Resistance

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    Given the increase in resistance to antibacterial agents, there is an urgent need for the development of new agents with novel modes of action. As an interim solution, it is also prudent to reinvestigate old or abandoned antibacterial compounds to assess their efficacy in the context of widespread resistance to conventional agents. In the 1970s, much work was performed on the development of peptide mimetics, exemplified by the phosphonopeptide, alafosfalin. We investigated the activity of alafosfalin, di-alanyl fosfalin and β-chloro-L-alanyl-β-chloro-L-alanine against 297 bacterial isolates, including carbapenemase-producing Enterobacterales (CPE) (n = 128), methicillin-resistant Staphylococcus aureus (MRSA) (n = 37) and glycopeptide-resistant enterococci (GRE) (n = 43). The interaction of alafosfalin with meropenem was also examined against 20 isolates of CPE. The MIC50 and MIC90 of alafosfalin for CPE were 1 mg/L and 4 mg/L, respectively and alafosfalin acted synergistically when combined with meropenem against 16 of 20 isolates of CPE. Di-alanyl fosfalin showed potent activity against glycopeptide-resistant isolates of Enterococcus faecalis (MIC90; 0.5 mg/L) and Enterococcus faecium (MIC90; 2 mg/L). Alafosfalin was only moderately active against MRSA (MIC90; 8 mg/L), whereas β-chloro-L-alanyl-β-chloro-L-alanine was slightly more active (MIC90; 4 mg/L). This study shows that phosphonopeptides, including alafosfalin, may have a therapeutic role to play in an era of increasing antibacterial resistance
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