6,310 research outputs found
Accuracy Analysis of the Measurement of Centre of Gravity and Moment of Inertia with a Swing
Floating devices under wave and current loads are typically designed based on numerical methods followed by a validation with experimental investigations. This allows an independent check due to the comparison of two different modelling approaches based on different assumptions. At an early stage of the project, numerical simulations are based on theoretical (ideal) values of the centre of gravity (CG) and moment of inertia (MI). The building process of a scaled model results very often in a requested simplification of certain parts, which can influence the CG and also the MI of the scaled model. Knowing those discrepancies allows us to improve the comparability of both approaches but the measurement of those values is connected with either a higher uncertainty or a high level of effort. A significant improvement of such measurements can be reached by the deployment of a specific experimental set-up. This paper presents the classification of the newly designed swing with a high accuracy inertial inclinometer, which was verified by the marker-based motion capturing system. The achieved experiences are useful for the future use of the set-up as well as similar investigations. The comparison with the theoretical values for the swing as well as an example model showed very good agreements and a high accuracy of few millimetres for the CG and an error smaller 1% for MI
Early Phonological Acquisition in a Set of English-Spanish Bilingual Twins
ProducciĂłn CientĂficaThis study is the first attempt to examine the early phonological development of bilingual twins. It sought to determine the extent to which the phonological acquisition of twins was similar, and the extent to which the phonological acquisition of the two languages was similar. Language samples from twin boys acquiring English and Spanish simultaneously were taken at 18, 19 and 20 months of age, in English and Spanish. The samples were analyzed using nine measures of phonological acquisition. A scale of phonological similarity was developed to quantify comparisons between the languages and between the children. The results indicated that the phonologies of the twins were 92% similar in each language, showing highly similar, but not identical systems. The phonologies of the languages were 71% similar, indicating that being twin did not impede early language separation
SiNx:Tb3+--Yb3+, an efficient down-conversion layer compatible with a silicon solar cell process
SiN x : Tb 3+-Yb 3+, an efficient down-conversion layer compatible with
silicon solar cell process Abstract Tb 3+-Yb 3+ co-doped SiN x down-conversion
layers compatible with silicon Photovoltaic Technology were prepared by
reactive magnetron co-sputtering. Efficient sensitization of Tb 3+ ions through
a SiN x host matrix and cooperative energy transfer between Tb 3+ and Yb 3+
ions were evidenced as driving mechanisms of the down-conversion process. In
this paper, the film composition and microstructure are investigated alongside
their optical properties, with the aim of maximizing the rare earth ions
incorporation and emission efficiency. An optimized layer achieving the highest
Yb 3+ emission intensity was obtained by reactive magnetron co-sputtering in a
nitride rich atmosphere for 1.2 W/cm and 0.15 W/cm power density
applied on the Tb and Yb targets, respectively. It was determined that
depositing at 200 {\textdegree}C and annealing at 850 {\textdegree}C leads to
comparable Yb 3+ emission intensity than depositing at 500 {\textdegree}C and
annealing at 600 {\textdegree}C, which is promising for applications toward
silicon solar cells.Comment: Solar Energy Materials and Solar Cells, Elsevier, 201
Identifying dynamical modules from genetic regulatory systems: applications to the segment polarity network
BACKGROUND
It is widely accepted that genetic regulatory systems are 'modular', in that the whole system is made up of smaller 'subsystems' corresponding to specific biological functions. Most attempts to identify modules in genetic regulatory systems have relied on the topology of the underlying network. However, it is the temporal activity (dynamics) of genes and proteins that corresponds to biological functions, and hence it is dynamics that we focus on here for identifying subsystems.
RESULTS
Using Boolean network models as an exemplar, we present a new technique to identify subsystems, based on their dynamical properties. The main part of the method depends only on the stable dynamics (attractors) of the system, thus requiring no prior knowledge of the underlying network. However, knowledge of the logical relationships between the network components can be used to describe how each subsystem is regulated. To demonstrate its applicability to genetic regulatory systems, we apply the method to a model of the Drosophila segment polarity network, providing a detailed breakdown of the system.
CONCLUSION
We have designed a technique for decomposing any set of discrete-state, discrete-time attractors into subsystems. Having a suitable mathematical model also allows us to describe how each subsystem is regulated and how robust each subsystem is against perturbations. However, since the subsystems are found directly from the attractors, a mathematical model or underlying network topology is not necessarily required to identify them, potentially allowing the method to be applied directly to experimental expression data
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Effectiveness of stratospheric solar-radiation management as a function of climate sensitivity
If implementation of proposals to engineer the climate through solar-radiation management (SRM) ever occurs, it is likely to be contingent on climate sensitivity. However, modelling studies examining the effectiveness of SRM as a strategy to offset anthropogenic climate change have used only the standard parameterizations of atmosphereâocean general circulation models that yield climate sensitivities close to the Coupled Model Intercomparison Project mean. Here, we use a perturbed-physics ensemble modelling experiment to examine how the response of the climate to SRM implemented in the stratosphere (SRM-S) varies under different greenhouse-gas climate sensitivities. When SRM-S is used to compensate for rising atmospheric concentrations of greenhouse gases, its effectiveness in stabilizing regional climates diminishes with increasing climate sensitivity. However, the potential of SRM-S to slow down unmitigated climate change, even regionally, increases with climate sensitivity. On average, in variants of the model with higher sensitivity, SRM-S reduces regional rates of temperature change by more than 90% and rates of precipitation change by more than 50%.Engineering and Applied Science
An analysis of civil aviation industry safety needs for the introduction of liquid hydrogen propulsion technology
Over the next few decades air travel is predicted to grow, with international agencies, manufacturers and governments predicting a considerable increase in aviation use. However, based on current fuel type, International Civil Aviation Organization (ICAO) project emissions from aviation are estimated to be seven to ten times higher in 2050 than in 1990. These conflicting needs are problematic and have led to the EU Flightpath 2050 targeting dramatic emissions reductions for the sector (75% CO2, 90% NOX by 2050).
One proposed solution, decreasing carbon emissions without stunting the increase in air travel, is hydrogen propulsion; a technology with clear environmental benefits. However, enabling the safe application of this fuel to aviation systems and industrial infrastructure would be a significant challenge. High-profile catastrophic incidents involving hydrogen, and the flammable and cryogenic nature of liquid hydrogen (LH2) have led to its reputation as a more dangerous substance than existing or alternative fuels. But, where they are used (in industry, transport, energy), with sufficient protocols, hydrogen can have a similar level of safety to other fuels. A knowledge of hazards, risks and the management of these becomes key to the integration of any new technology.
Using assessments, and a gap analysis approach, this paper examines the civil aviation industry requirements, from a safety perspective, for the introduction of LH2 fuel use. Specific proposed technology assessments are used to analyze incident likelihood, consequence impact, and ease of remediation for hazards in LH2 systems, and a gap analysis approach is utilized to identify if existing data is sufficient for reliable technology safety assessment. Outstanding industry needs are exposed by both examining challenges that have been identified in transport and industrial areas, and by identifying the gaps in current knowledge that are preventing credible assessment, reliable comparison to other fuels and the development of engineering systems.
This paper demonstrates that while hydrogen can be a safe and environmentally friendly fuel option, a significant amount of work is required for the implementation of LH2 technology from a mass market perspective
Amphetamine Modulates Excitatory Neurotransmission through Endocytosis of the Glutamate Transporter EAAT3 in Dopamine Neurons
SummaryAmphetamines modify the brain and alter behavior through mechanisms generally attributed to their ability to regulate extracellular dopamine concentrations. However, the actions of amphetamine are also linked to adaptations in glutamatergic signaling. We report here that when amphetamine enters dopamine neurons through the dopamine transporter, it stimulates endocytosis of an excitatory amino acid transporter, EAAT3, in dopamine neurons. Consistent with this decrease in surface EAAT3, amphetamine potentiates excitatory synaptic responses in dopamine neurons. We also show that the process of internalization is dynamin- and Rho-mediated and requires a unique sequence in the cytosolic C terminus of EAAT3. Introduction of a peptide based on this motif into dopamine neurons blocks the effects of amphetamine on EAAT3 internalization and its action on excitatory responses. These data indicate that the internalization of EAAT3 triggered by amphetamine increases glutamatergic signaling and thus contributes to the effects of amphetamine on neurotransmission
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