Geometric Morphometrics of Gary Dart Points from the Davy Crockett National Forest

Three-dimensional scans of Gary dart points recovered from the Davy Crockett National Forest are employed in tests of basal morphology by site, size (allometry), and asymmetry. Variability in basal morphology for Gary points from sites on the Davy Crockett National Forest is presented and compared to specimens from the published type books. The hypothesis that Gary basal morphology differs between sites containing Woodland-era sand temped ceramics and those where no sand tempered ceramics were recovered is then tested and the results discussed

Village proposal for mixed use reappropriation of the industrial landscape

Thesis: S.B. in Art and Design, Massachusetts Institute of Technology, Department of Architecture, 2003.Cataloged from PDF version of thesis. Vita.Includes bibliographical references (pages 78-81).This urban design thesis addresses the transformation of single-use industrial space to mixed-use public and private space, linking pedestrian and vehicular paths within the village of Sussex, WI. The industrial revolution often reinforced the separation of functions (residential, commercial, industrial, civic) into separate buildings and often separate districts. In the midst of the built landscape, former places of industrial work and production are now large tracts of underused land. The reappropriation of urban and suburban industrial space provides the opportunity to create mixed-use, vital spaces relating well to pedestrian and vehicular traffic. Such reappropriation deals with the site not only visually, but also in terms of the way its history and natural processes are transformed. The reappropriation is essential on the urban scale of a village, and I choose to explore it at the site of the former quarry and canning factory in Sussex, WI. As a central link between Main Street and the pedestrian Bugline trail, the six acre urban landscape design (in several phases) includes over 100,000 indoor square feet of residential, commercial, and public spaces. This thesis examines issues of ownership, financing, phasing, landscaping, and architecture as they apply in the village. Through an urban design analysis and a series of schemes in drawings and models, the process shows the role of natural processes and public sector involvement in the site development, along with creative solutions to address these relationships on the site. It uses the prominent scale and location of former industrial land and spaces as a point of departure for improving a location's sense of local character, its local economy, its neighborhoods, and its public space.by David M. Foxe.S.B. in Art and Desig

Structuring beyond architecture

Thesis (M. Arch.)--Massachusetts Institute of Technology, Dept. of Architecture, 2006.This electronic version was submitted by the student author. The certified thesis is available in the Institute Archives and Special Collections.Vita.Includes bibliographical references (p. 170-179).This thesis explores the layering and negotiation of structural devices in urban settings. Its point of departure is a series of patterns of how structural design and urban design interact and overlap, from which are developed design strategies that encourage differentiation and the ability to accommodate change in the future. Therefore, the thesis traces an approach for growth rather than simply specifying a particular isolated solution to a single local set of conditions: a machine rather than a spare part. The overarching structural challenge which I have investigated as a vehicle for this approach is for foundation systems spanning over shallowly buried subway and highway tunnels at a site adjacent to the Fort Point Channel neighborhood in South Boston. This challenge, facing many cities around the world, provokes the problem of designing and creating the structure of support in these areas to enable more - rather than less - creative spatial possibilities above the ground. The subsequent proposal details a system of linear bundles - high-performance concrete beams rooted down to bedrock, along with utilities, walkways, plantings, open spaces, loading conditions, property rights, and implementation strategies bundled together -(cont.) as well as the bridges, piers, and canopies which articulate the termination conditions at the bundles' ends. This thesis asserts that architecture as a discipline and as a creation can negotiate urban conditions and grade separations with structural gestures, shaping the spaces and volumes immediately above and below the constructed ground, and thus addressing both pedestrian and vehicular movement in urban environments. The project leaps between the scales of internal structure and the external urban realm, and situates architecture at this boundary. This exploration integrates relationships with historical precedents of Technological Modernism as well as connections to biological metaphors, to fiction and imagination, to music and harmony, and to broader principles and qualities for shaping and implementing structures in urban spaces. This thesis is the final component for the author's completion of the Master of Architecture degree as well as the interdepartmental Urban Design Certificate.by David M. Foxe.M.Arch

Addressing Survey Bias: Maxent Models and Public Archaeology at the Davy Crockett National Forest

Over the past 30+ years, compliance-based archaeological projects conducted on the Davy Crockett National Forest have yielded an impressive contribution to the archaeological record. However, those efforts were limited to specific survey areas based upon specific needs. To begin to address survey bias and the impact that it can have on site probability models, a stratified random sample of 50 locations was generated for the forest. In early 2018, a public archaeology (Passport-in-Time) project was used to engage interested volunteers who assisted in testing these sample locations. These results, as well as other new data, were added to the maxent site probability model in advance of running a second iteration. A second call for volunteers in early 2019 will aid with site relocation and delineation of known resources, as well as an additional test using a new stratified random sample

First Test of Habitat Suitability Models for the Davy Crockett National Forest

The test for this suite of models was conducted as a double-blind survey since neither the United States Forest Service personnel (excepting Garcia) nor the participants were provided with any information regarding the model in advance of testing. Input from the model was shared with the crew the day after each location was tested. Enlistment of the double-blind survey method aids in reducing survey bias. Collection of data for this project begins with the stratified random sample. The sample consists of random locations throughout compartments of the Davy Crockett National Forest. Those locations not visited in the first test of the model will be surveyed following the Passport-in-Time project. To test the stratified random sample, a three-by-three grid of nine shovel tests were excavated at each location. Those resources discovered during the survey were assigned a forest-specific number, were documented, and the collections were subsequently transferred to the Center for Regional Heritage Research at Stephen F. Austin State University for analysis and processing

Historic Image Gallery for the National Forests and Grasslands in Texas

Historic images curated at the National Forests and Grasslands in Texas (NFGT) have been digitized and uploaded to the collections of the Center for Regional Heritage Research in the institutional repository of Stephen F. Austin State University. Searchable metadata is included with each image, and metadata can be harvested through the Open Archives Initiative Protocol for Metadata Harvesting (OAI-PMH). All images are made available at three resolutions; full, medium, and thumbnail, and are available for download under a Creative Commons Attribution-No Derivative Works 4.0 International License (https://creativecommons.org/licenses/by-nd/4.0/). Data in the collection is compliant with the new European Union General Data Protection Regulation, ensuring compliance with the most recent privacy guidelines

Intrafamilial Phenotypic Variability in the C9orf72 Gene Expansion: 2 Case Studies

The C9orf72 genetic mutation is the most common cause of familial frontotemporal dementia (FTD) and motor neuron disease (MND). Previous family studies suggest that while some common clinical features may distinguish gene carriers from sporadic patients, the clinical features, age of onset and disease progression vary considerably in affected patients. Whilst disease presentations may vary across families, age at disease onset appears to be relatively uniform within each family. Here, we report two individuals with a C9orf72 repeat expansion from two generations of the same family with markedly different age at disease onset, clinical presentation and disease progression: one who developed motor neuron and behavioural symptoms in their mid 40s and died 3 years later with confirmed TDP-43 pathology and MND; and a second who developed cognitive and mild behavioural symptoms in their mid 70s and 8 years later remains alive with only slow deterioration. This report highlights the phenotypic variability, including age of onset, within a family with the C9orf72 repeat expansion

Addenbrooke’s Cognitive Examination III: Psychometric Characteristics and Relations to Functional Ability in Dementia

Objectives: The Addenbrooke’s Cognitive Examination (ACE) is a common cognitive screening test for dementia. Here, we examined the relationship between the most recent version (ACE-III) and its predecessor (ACE-R), determined ACE- III cutoff scores for the detection of dementia, and explored its relationship with functional ability. Methods: Study 1 included 199 dementia patients and 52 healthy controls who completed the ACE-III and ACE-R. ACE-III total and domain scores were regressed on their corresponding ACE-R values to obtain conversion formulae. Study 2 included 331 mixed dementia patients and 87 controls to establish the optimal ACE-III cutoff scores for the detection of dementia using receiver operator curve analysis. Study 3 included 194 dementia patients and their carers to investigate the relationship between ACE-III total score and functional ability. Results: Study 1: ACE-III and ACE-R scores differed by ≤1 point overall, the magnitude varying according to dementia type. Study 2: a new lower bound cutoff ACE-III score of 84/100 to detect dementia was identified (compared with 82 for the ACE-R). The upper bound cutoff score of 88/100 was retained. Study 3: ACE-III scores were significantly related to functional ability on the Clinical Dementia Rating Scale across all dementia syndromes, except for semantic dementia. Conclusions: This study represents one of the largest and most clini- cally diverse investigations of the ACE-III. Our results demonstrate that the ACE-III is an acceptable alternative to the ACE-R. In addition, ACE-III performance has broader clinical implications in that it relates to carer reports of functional impairment in most common dementias. (JINS, 2018, 24, 854–863

Polygenic Risk for Alzheimer's Disease is not Associated with Cognitive Ability or Cognitive Aging in Non-Demented Older People

Peer reviewedPublisher PD

Transcranial alternating current stimulation to the inferior parietal lobe decreases Mu suppression to egocentric, but not allocentric hand movements

Egocentric vs. allocentric perspective during observation of hand movements has been related to self-other differentiation such that movements observed from an egocentric viewpoint have been considered as self-related while movements observed from an allocentric viewpoint have been considered as belonging to someone else. Correlational studies have generally found that egocentric perspective induces greater neurophysiological responses and larger behavioural effects compared to an allocentric perspective. However, recent studies question previous findings by reporting greater (μ) suppression and greater transcranial magnetic stimulation (TMS) induced motor-evoked potentials (MEPs) during observation of allocentric compared to egocentric movements. Furthermore, self-other differentiation has been generally related to activity within the inferior parietal lobe (IPL), but direct evidence for a causal and functional role of IPL in self-other differentiation is lacking. The current study was therefore designed to investigate the influence that IPL exerts on self-other differentiation. To this aim, we measured the impact of individually adjusted alpha-tuned transcranial alternating current stimulation (tACS) applied over IPL on μ-suppression during hands movement observation from an egocentric and allocentric perspective. Electroencephalography (EEG) was recorded during movement observation before and immediately after tACS. Results demonstrated that tACS decreased μ-reactivity over sensorimotor (but not visual) regions for egocentric (but not allocentric) movement observation providing direct evidence for a causal involvement of IPL in the observation of self- but not other-related hands movement