Parasitic Hymenoptera as Forensic Indicator Species

Necrophagous insects are the most important ecological evidence associated with a decomposing corpse. Insects provide insight into estimating the post-mortem interval (PMI), assessing whether a corpse has been moved, use in toxicological analyses, and provide utility in surveillance and as sniffer systems. Necrophagous Diptera are regarded as the most important forensic indicator species, largely because they colonize a corpse within minutes of death. Other types of carrion-inhabiting insects also offer value, although more limited than flies, to forensic investigations. Perhaps, the most neglected of these groups is the parasitic Hymenoptera, a group comprising several species that utilize necrophagous flies as natural hosts. Parasitic wasps extend the PMI window to include the period of time after necrophagous flies have emerged to when a corpse is discovered. Wasp host preferences and seasonal occurrences can reveal if a body was moved from another location prior to discovery. Foraging behavior of adults can be used to locate concealed bodies and potentially aid in combating entomological terrorism agents. Presently, the full potential of parasitic Hymenoptera as alternate forensic indicator species has not been explored. This chapter relates the life history characteristics of parasitic wasps to their potential usefulness in forensic applications

Experimental Investigation of the NASA Common Research Model with a Natural Laminar Flow Wing in the NASA Langley National Transonic Facility

A test of the new NASA Common Research Model with a Natural Laminar Flow (CRMNLF) semispan wing in the NASA Langley National Transonic Facility (NTF) was completed in October 2018. The main focus of this test was the evaluation of the extent of laminar flow on the CRM-NLF wing at various Reynolds numbers and test conditions. During this test, data were acquired at chord Reynolds numbers from 10 to 30 million and at Mach numbers ranging from 0.84 to 0.86. This investigation provided valuable insight into the necessary procedures for laminar flow testing in the NTF. It also significantly advanced the new carbonbased heating layer technique to improve the quality of transition visualization data from temperature sensitive paint (TSP) in a cryogenic wind tunnel

Fluxoid formation: size effects and non-equilibrium universality

Simple causal arguments put forward by Kibble and Zurek suggest that the scaling behaviour of condensed matter at continuous transitions is related to the familiar universality classes of the systems at quasi-equilibrium. Although proposed 25 years ago or more, it is only in the last few years that it has been possible to devise experiments from which scaling exponents can be determined and in which this scenario can be tested. In previous work, an unusually high Kibble-Zurek scaling exponent was reported for spontaneous fluxoid production in a single isolated superconducting Nb loop, albeit with low density. Using analytic approximations backed up by Langevin simulations, we argue that densities as small as these are too low to be attributable to scaling, and are conditioned by the small size of the loop. We also reflect on the physical differences between slow quenches and small rings, and derive some criteria for these differences, noting that recent work on slow quenches does not adequately explain the anomalous behaviour seen here.Comment: 7 pages, 4 figures, presentation given at CMMP 201

Anti-inflammatories in Alzheimer’s disease – potential therapy or spurious correlate?

Epidemiological evidence suggests non-steroidal anti-inflammatories (NSAIDs) reduce the risk of Alzheimer’s disease. However, clinical trials have found no evidence of NSAID efficacy. This incongruence may be due to the wrong NSAIDs being tested in robust clinical trials or the epidemiological findings being caused by confounding factors. Therefore, this study used logistic regression and the innovative approach of negative binomial generalised linear mixed modelling to investigate both prevalence and cognitive decline, respectively, in the Alzheimer’s Disease NeuroImaging dataset for each commonly used NSAID and paracetamol. Use of most NSAIDs were associated with reduced Alzheimer’s disease prevalence yet no effect on cognitive decline was observed. Paracetamol had a similar effect on prevalence to these NSAIDs suggesting this association is independent of the anti-inflammatory effects and that previous results may be due to spurious associations. Interestingly, diclofenac use was significantly associated with both reduce incidence and slower cognitive decline warranting further research into the potential therapeutic effects of diclofenac in Alzheimer’s disease

Preliminary Results from an Experimental Assessment of a Natural Laminar Flow Design Method

A 5.2% scale semispan model of the new Common Research Model with Natural Laminar Flow (CRM-NLF) was tested in the National Transonic Facility (NTF) at the NASA Langley Research Center. The model was tested at transonic cruise flight conditions with Reynolds numbers based on mean aerodynamic chord ranging from 10 to 30 million. The goal of the test was to experimentally validate a new design method, referred to as Crossflow Attenuated NLF (CATNLF), which shapes airfoils to have pressure distributions that delay transition on wings with high sweep and Reynolds numbers. Additionally, the test aimed to characterize the NTF laminar flow testing capabilities, as well as establish best practices for laminar flow wind tunnel testing. Preliminary results regarding the first goal of validating the new design method are presented in this paper. Experimental data analyzed in this assessment include surface pressure data and transition images. The surface pressure data acquired during the test agree well with computational fluid dynamics (CFD) results. Transition images at a variety of Reynolds numbers and angles of attack are presented and compared to computational transition predictions. The experimental data are used to assess transition due to a turbulent attachment line, as well as crossflow and Tollmien-Schlichting modal instabilities. Preliminary results suggest the CATNLF design method is successful at delaying transition on wings with high sweep. Initial analysis of the transition front images showed transition Reynolds numbers that exceed historic experimental values at similar sweep angles. , section lif

GAP WORK project report: training for youth practitioners on tackling gender-related violence

This project sought to challenge gender-related violence against (and by) children and young people by developing training for practitioners who have everyday contact with general populations of children and young people (‘youth practitioners’). Through improved knowledge and understanding practitioners can better identify and challenge sexist, sexualising, homophobic or controlling language and behaviour, and know when and how to refer children and young people to the most appropriate support services. This summary outlines the Project and our initial findings about the success of the four training programmes developed and piloted.Co-funded by the DAPHNE III programme of the EU

Venom Proteins of the Parasitoid Wasp Nasonia vitripennis: Recent Discovery of an Untapped Pharmacopee

Adult females of Nasonia vitripennis inject a venomous mixture into its host flies prior to oviposition. Recently, the entire genome of this ectoparasitoid wasp was sequenced, enabling the identification of 79 venom proteins. The next challenge will be to unravel their specific functions, but based on homolog studies, some predictions already can be made. Parasitization has an enormous impact on hosts physiology of which five major effects are discussed in this review: the impact on immune responses, induction of developmental arrest, increases in lipid levels, apoptosis and nutrient releases. The value of deciphering this venom is also discussed

Aquatic biosurvey of the Lovell River on UNH land

We assessed the physical, chemical and biological conditions at two sites along the Lovell River on University of New Hampshire (UNH) -owned conservation land. The discharge was 4.4 m3 s-1 at Site 1 and 5.7 m3 s -1 downstream at Site 2. Canopy coverage ranged from 8-25%. Canopy was dominated by Eastern Hemlock (79-84%). Much of the stream was strewn with large boulders and the substrate consisted of rocks of highly variable sizes ( 3-549 cm dia.). Specific conductivity (22.1-23.3 µS), pH (6.4) and temperature (7.9-8.3 °C) varied little between sites. Macro-invertebrate bio-indices indicated either excellent water quality with no apparent organic pollution (3.0/10) or good water quality with possible slight organic pollution (4.4/10)

Venom-Induced Immunosuppression: An Overview of Hemocyte-Mediated Responses

Parasitic wasps are important natural enemies of several insect pests. They use a variety of methods to modulate their insect host for their progeny to develop. For example, the female wasp needs to avoid or suppress the host immune responses by introducing venom with or without virus like particles and/or polydnaviruses. The aim of this paper is to provide a synthesis of current knowledge regarding the immunosuppression of host immunity with venom in parasitoids that are devoid of symbiotic viruses. Special emphasis is given through disabling host hemocytes by venom of the endoparasitoid Pimpla turionellae (Hymenoptera: Ichneumonidae) with comparisons of venoms from other parasitoid species

The Distance and Metallicity of the Newly Discovered, Nearby Irregular Galaxy HIZSS3

HIZSS3 is an H I source in the Zone of Avoidance. Its radio characteristics are consistent with it being nearby (~ 1.8 Mpc) low-mass dwarf irregular (dIm) galaxy. It contains a modest H II region, but its stellar population has not been resolved by optical observations. MMT spectra of the H II region are used to derive the line-of-sight extinction (E(B-V) = 1.41 +/- 0.04) and gas metallicity (log O/H + 12 ~ 7.8). ESO VLT near-IR images clearly reveal a resolved stellar population. Narrow-band Pbeta images of the H II region are used in combination with previously published Halpha data to obtain an independent line-of-sight extinction estimate: E(B-V) = 1.32 +/- 0.04. The adopted foreground extinction is E(B-V) = 1.36 +/- 0.06. Based on the K-band luminosity function and K,J-K color-magnitude diagram, the apparent magnitude and color of the tip of the red-giant branch (TRGB) are derived. In turn, these parameters are combined with the adopted foreground extinction to estimate the distance (1.69 +/- 0.07 Mpc) and mean red giant branch metallicity ([Fe/H] = -0.5 +/- 0.1). As an ensemble, these new observations significantly strengthen the conclusion that HIZSS3 is a newly discovered low-mass dIm lurking behind the Milky Way in the outskirts of the Local Group.Comment: Accepted, scheduled for ApJ, 10 Apr 05, V623 ; 14 page