7,409 research outputs found
Watch-wearing as a marker of conscientiousness
Several aspects of an individual’s appearance have been shown to predict personality and related behaviour. While some of these cues are grounded in biology (e.g., the human face), other aspects of a person’s appearance can be actively controlled (e.g., clothing). In this paper, we consider a common fashion accessory, the wristwatch. In an exploratory sample (N > 100) and a confirmatory sample (N > 600), we compared big-five personality traits between individuals who do or do not regularly wear a standard wristwatch. Significantly higher levels of conscientiousness were observed in participants who wore a watch. In a third study (N = 85), watch wearers arrived significantly earlier to appointments in comparison to controls. These results are discussed in relation to enclothed cognition and the rise of wearable technology including smartwatches
A temporal switch model for estimating transcriptional activity in gene expression
Motivation: The analysis and mechanistic modelling of time series gene expression data provided by techniques such as microarrays, NanoString, reverse transcription–polymerase chain reaction and advanced sequencing are invaluable for developing an understanding of the variation in key biological processes. We address this by proposing the estimation of a flexible dynamic model, which decouples temporal synthesis and degradation of mRNA and, hence, allows for transcriptional activity to switch between different states.
Results: The model is flexible enough to capture a variety of observed transcriptional dynamics, including oscillatory behaviour, in a way that is compatible with the demands imposed by the quality, time-resolution and quantity of the data. We show that the timing and number of switch events in transcriptional activity can be estimated alongside individual gene mRNA stability with the help of a Bayesian reversible jump Markov chain Monte Carlo algorithm. To demonstrate the methodology, we focus on modelling the wild-type behaviour of a selection of 200 circadian genes of the model plant Arabidopsis thaliana. The results support the idea that using a mechanistic model to identify transcriptional switch points is likely to strongly contribute to efforts in elucidating and understanding key biological processes, such as transcription and degradation
Medication treatment perceptions, concerns and expectations among depressed individuals with Type I Bipolar Disorder
BACKGROUND: Subjective experience of illness affects outcomes among populations with bipolar disorder (BD). This cross-sectional study combined qualitative and quantitative approaches to evaluate perceived treatment effects, concerns and expectations among 90 individuals with BD. METHODS: Adults with type I BD, mean age 36.6 years, 51% women, completed a semi-structured interview that was audio taped, transcribed, coded and analyzed along emergent themes. Quantitative scales measured depressive symptoms (Hamilton Depression Scale/HAMD), psychopathology (Clinical Global Impression/CGI), and insight and treatment attitudes (Insight and Treatment Attitudes Questionnaire/ITAQ). RESULTS: Individuals had moderate depression and psychopathology with good insight into need for treatment. Drug treatment was perceived as beneficial, by “stabilizing” or “balancing” mood (42%, N=38), decreasing anxiety/depressive symptoms (19%, N=17) and improving sleep (10%, N=9). While 39%, (N=35) of individuals denied medication concerns, nearly 29%, (N=26) feared possible long-term effects, particularly diabetes or liver/kidney damage. Media stories and advertisements contributed to medication fears. Hopes and expectations for treatment ranged from those that were symptom or functional status-based, such as desiring mood stabilization and elimination of specific symptoms (23%, N=21), to more global hopes such as “being normal” (20%, N=18) or “cured” (18%, N=16). LIMITATIONS: Limitations include relatively small sample, lack of a comparator, inclusion of only depressed individuals and those willing to discuss their illness experience. CONCLUSIONS: While individuals with BD appreciate the effects of medications, concerns regarding adverse effects and discrepancy between actual and hoped-for outcomes can be substantial. Subjective experience with medications using qualitative and quantitative methods should be explored in order to optimize treatment collaboration and outcomes
Resonance energy transfer: The unified theory revisited
Resonanceenergy transfer (RET) is the principal mechanism for the intermolecular or intramolecular redistribution of electronic energy following molecular excitation. In terms of fundamental quantum interactions, the process is properly described in terms of a virtual photon transit between the pre-excited donor and a lower energy (usually ground-state) acceptor. The detailed quantum amplitude for RET is calculated by molecular quantum electrodynamical techniques with the observable, the transfer rate, derived via application of the Fermi golden rule. In the treatment reported here, recently devised state-sequence techniques and a novel calculational protocol is applied to RET and shown to circumvent problems associated with the usual method. The second-rank tensor describing virtual photon behavior evolves from a Green’s function solution to the Helmholtz equation, and special functions are employed to realize the coupling tensor. The method is used to derive a new result for energy transfer systems sensitive to both magnetic- and electric-dipole transitions. The ensuing result is compared to that of pure electric-dipole–electric-dipole coupling and is analyzed with regard to acceptable transfer separations. Systems are proposed where the electric-dipole–magnetic-dipole term is the leading contribution to the overall rate
Missed medical appointments during shifts to and from daylight saving time
Transitions into and out of Daylight Saving Time (DST) can provide insights into how a minor change to a regular sleep–wake cycle can inadvertently affect health. We examined the relationship between DST and missed medical appointments. Using a large dataset, the proportion of missed appointments were examined prior and post spring and autumn clock changes. As predicted, the number of missed medical appointments significantly increased following the spring (forward) clock change and the week of the clock change. This trend was reversed following the transition out of DST. The implications of scheduling appointments around DST to increase attendance are discussed
Lifting of Ir{100} reconstruction by CO adsorption: An ab initio study
The adsorption of CO on unreconstructed and reconstructed Ir{100} has been
studied, using a combination of density functional theory and thermodynamics,
to determine the relative stability of the two phases as a function of CO
coverage, temperature and pressure. We obtain good agreement with
experimentaldata. At zero temperature, the (1X5) reconstruction becomes less
stable than the unreconstructed (1X1) surface when the CO coverage exceeds a
critical value of 0.09 ML. The interaction between CO molecules is found to be
repulsive on the reconstructed surface, but attractive on the unreconstructed,
explaining the experimental observation of high CO coverage on growing (1X1)
islands. At all temperatures and pressures, we find only two possible stable
states: 0.05 ML CO c(2X2) overlayer on the (1X1) substrate, and the clean
(15) reconstructed surface.Comment: 31 page
Calculation of the heavy-hadron axial couplings g_1, g_2, and g_3 using lattice QCD
In a recent letter [Phys. Rev. Lett. 108, 172003 (2012), arXiv:1109.2480] we
have reported on a lattice QCD calculation of the heavy-hadron axial couplings
, , and . These quantities are low-energy constants of
heavy-hadron chiral perturbation theory (HHPT) and are related to the
, , and couplings.
In the following, we discuss important details of the calculation and give
further results. To determine the axial couplings, we explicitly match the
matrix elements of the axial current in QCD with the corresponding matrix
elements in HHPT. We construct the ratios of correlation functions used
to calculate the matrix elements in lattice QCD, and study the contributions
from excited states. We present the complete numerical results and discuss the
data analysis in depth. In particular, we demonstrate the convergence of
HHPT for the axial-current matrix elements at pion masses up to
about 400 MeV and show the impact of the nonanalytic loop contributions.
Finally, we present additional predictions for strong and radiative decay
widths of charm and bottom baryons.Comment: 42 pages, 20 figures, updated calculation of Xi_b^{*0} width using
mass measurement from CMS, published versio
Warm-hot Gas in X-ray Bright Galaxy Clusters and the H I-deficient Circumgalactic Medium in Dense Environments
We analyze the intracluster medium (ICM) and circumgalactic medium (CGM) in 7
X-ray detected galaxy clusters using spectra of background QSOs (HST-COS/STIS),
optical spectroscopy of the cluster galaxies (MMT/Hectospec and SDSS), and
X-ray imaging/spectroscopy (XMM-Newton and Chandra). First, we report a very
low covering fraction of H I absorption in the CGM of these cluster galaxies,
f_c = 25% +25%/-15%, to stringent detection limits (log N(H I) < 13 cm^-2). As
field galaxies have an H I covering fraction of ~100% at similar radii, the
dearth of CGM H I in our data indicates that the cluster environment has
effectively stripped or overionized the gaseous halos of these cluster
galaxies. Second, we assess the contribution of warm-hot (10^5 - 10^6 K) gas to
the ICM as traced by O VI and broad Ly-alpha (BLA) absorption. Despite the high
signal-to-noise of our data, we do not detect O VI in any cluster, and we only
detect BLA features in the QSO spectrum probing one cluster. We estimate that
the total column density of warm-hot gas along this line of sight totals to ~3%
of that contained in the hot T > 10^7 K X-ray emitting phase. Residing at high
relative velocities, these features may trace pre-shocked material outside the
cluster. Comparing gaseous galaxy halos from the low-density 'field' to galaxy
groups and high-density clusters, we find that the CGM is progressively
depleted of H I with increasing environmental density, and the CGM is most
severely transformed in galaxy clusters. This CGM transformation may play a key
role in environmental galaxy quenching.Comment: 21 pages, 14 figures, 6 tables. Accepted for publication in MNRA
Viewers base estimates of face matching accuracy on their own familiarity: Explaining the photo-ID paradox
Matching two different images of a face is a very easy task for familiar viewers, but much harder for unfamiliar viewers. Despite this, use of photo-ID is widespread, and people appear not to know how unreliable it is. We present a series of experiments investigating bias both when performing a matching task and when predicting other people’s performance. Participants saw pairs of faces and were asked to make a same/different judgement, after which they were asked to predict how well other people, unfamiliar with these faces, would perform. In four experiments we show different groups of participants familiar and unfamiliar faces, manipulating this in different ways: celebrities in experiments 1 to 3 and personally familiar faces in experiment 4. The results consistently show that people match images of familiar faces more accurately than unfamiliar faces. However, people also reliably predict that the faces they themselves know will be more accurately matched by different viewers. This bias is discussed in the context of current theoretical debates about face recognition, and we suggest that it may underlie the continued use of photo-ID, despite the availability of evidence about its unreliability
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