Opfermitverantwortung beim Betrug

Isolation of the peptide fraction P1-RPC-C18 by reverse-phase chromatography in a C4-column (RPC-C4) and mass spectrometry profile showing the peptide ions. (PDF 66 kb

GESTÃO DA INOVAÇÃO DE CAPITAL INTELECTUAL EM PESQUISA E DESENVOLVIMENTO

Intellectual capital is becoming the pre-eminent resource for creating wealth based on knowledge generated by research and development - R&D. Knowledge-based assets have increased the importance to develop and maintain competitive advantage in R&D. The paper develops a working definition of intellectual capital for R&D and a framework for identifying and classifying these components. This provides exploratory systems and processes useful for meaningful innovation management. Intellectual Capital is, in fact, a term used to describe organizations of knowledge which use their intangible assets as resources to secure competitive advantages. They also use other intangible assets, such as specific techniques and products, patented processes, know-how inherent to production and to the knowledge of the market, and their own competitive intelligence. As knowledge becomes the central asset in productive and strategic terms, mainly on innovation policies, the success of the organization depends evermore on the ability to measure and optimize Intellectual Capital. The paper presents and applies a model to evaluate Intellectual Capital employing a multi-criteria decision method. This method makes it possible not only measure intangible assets such as Intellectual Capital, but also to prescribe policies for optimizing intangible assets or, in other words, how and where the organization should invest, at a minimum effort, in order to improve its market value in the technology-driven world with innovation management in R&D.TEXTO (PDF) EM INGLÊSO capital intelectual vem se tornando o recurso de maior destaque na criação de riqueza baseada no conhecimento gerado por pesquisa e desenvolvimento - P&D. Os ativos de conhecimento aumentaram a importância de se desenvolver e manter a vantagem competitiva em P&D. Este trabalho desenvolve uma definição prática de capital intelectual para P&D e um modelo de identificação e classificação destes componentes, o qual fornece sistemas exploratórios e processos úteis para uma gestão da inovação significativa. Capital Intelectual é um termo usado para descrever organizações de conhecimento que empregam seus ativos intangíveis como recursos para garantir vantagens competitivas. Eles também utilizam outros ativos intangíveis, tais como técnicas e produtos específicos, processos patenteados, know-how inerente à produção e ao conhecimento do mercado, além de sua própria inteligência competitiva. Uma vez que o conhecimento torna-se o principal ativo em termos produtivos e estratégicos, especialmente em políticas de inovação, o sucesso da organização cada vez mais depende da habilidade de medir e otimizar  o Capital Intelectual. Este trabalho apresenta e aplica um modelo de avaliação do Capital Intelectual utilizando um método decisório multi-critério. Este método possibilita não apenas medir ativos intangíveis como Capital Intelectual, mas também prescrever políticas de otimização de ativos intangíveis ou, em outras palavras, como e onde a organização deve investir, com um mínimo de esforço, com o intuito de melhorar seu valor de mercado num mundo voltado para a tecnologia, utilizando a gestão da inovação em P&

GESTÃO DA INOVAÇÃO DE CAPITAL INTELECTUAL EM PESQUISA E DESENVOLVIMENTO

Intellectual capital is becoming the pre-eminent resource for creating wealth based on knowledge generated by research and development - R&D. Knowledge-based assets have increased the importance to develop and maintain competitive advantage in R&D. The paper develops a working definition of intellectual capital for R&D and a framework for identifying and classifying these components. This provides exploratory systems and processes useful for meaningful innovation management. Intellectual Capital is, in fact, a term used to describe organizations of knowledge which use their intangible assets as resources to secure competitive advantages. They also use other intangible assets, such as specific techniques and products, patented processes, know-how inherent to production and to the knowledge of the market, and their own competitive intelligence. As knowledge becomes the central asset in productive and strategic terms, mainly on innovation policies, the success of the organization depends evermore on the ability to measure and optimize Intellectual Capital. The paper presents and applies a model to evaluate Intellectual Capital employing a multi-criteria decision method. This method makes it possible not only measure intangible assets such as Intellectual Capital, but also to prescribe policies for optimizing intangible assets or, in other words, how and where the organization should invest, at a minimum effort, in order to improve its market value in the technology-driven world with innovation management in R&D.TEXTO (PDF) EM INGLÊSO capital intelectual vem se tornando o recurso de maior destaque na criação de riqueza baseada no conhecimento gerado por pesquisa e desenvolvimento - P&D. Os ativos de conhecimento aumentaram a importância de se desenvolver e manter a vantagem competitiva em P&D. Este trabalho desenvolve uma definição prática de capital intelectual para P&D e um modelo de identificação e classificação destes componentes, o qual fornece sistemas exploratórios e processos úteis para uma gestão da inovação significativa. Capital Intelectual é um termo usado para descrever organizações de conhecimento que empregam seus ativos intangíveis como recursos para garantir vantagens competitivas. Eles também utilizam outros ativos intangíveis, tais como técnicas e produtos específicos, processos patenteados, know-how inerente à produção e ao conhecimento do mercado, além de sua própria inteligência competitiva. Uma vez que o conhecimento torna-se o principal ativo em termos produtivos e estratégicos, especialmente em políticas de inovação, o sucesso da organização cada vez mais depende da habilidade de medir e otimizar  o Capital Intelectual. Este trabalho apresenta e aplica um modelo de avaliação do Capital Intelectual utilizando um método decisório multi-critério. Este método possibilita não apenas medir ativos intangíveis como Capital Intelectual, mas também prescrever políticas de otimização de ativos intangíveis ou, em outras palavras, como e onde a organização deve investir, com um mínimo de esforço, com o intuito de melhorar seu valor de mercado num mundo voltado para a tecnologia, utilizando a gestão da inovação em P&

Semi-blind Channel Monitoring Mechanisms for Post-switchover Wireless Microphones

Abstract-In this paper, we discuss the use of spectrum sensing as a contingency for future wireless microphones (WM). We represent post-switchover operation conditions as a framework where WM sense for signals of digital television (DTV) and TV band devices (TVBD). Using this model, we propose two semi-blind channel monitoring mechanisms that ensure quality of service through fast and fine sensing. To implement such mechanisms, we analyze the pros and cons of five potential detection methods with respect to computational complexity, amount of prior information required for detection, classification ability, and performance under AWGN and frequency-selective fading. Our analysis suggests that methods based on the cyclic prefix (CP) are promising for fast sensing as long as portable TVBD can be detected. With respect to fine sensing, we suggest methods that exploit scattered pilots to improve classification ability and robustness against noise uncertainty, CP length variations, and multipath. The proposed mechanisms incur no performance loss in comparison to fast sensing methods in isolation

Tmesiphantes mirim sp. nov. (Araneae: Theraphosidae) from the Atlantic Forest of Bahia, Brazil, biogeographical notes and identification keys for species of the genus

A new species of Tmesiphantes Simon, 1892 is described and illustrated, based on eight male specimens collected at the Una Biological Reserve, southern state of Bahia, Brazil. It is distinguished by the morphology of male palpal bulb and tibial apophysis. The new species is very small and is the smallest theraphosid described to date (body length 5.5 mm). It is distinguished from congeners by the size, which vary from 12 mm (T. riopretano) to 23.8 mm (T. nubilus) in other species of the genus, aspect of palpal bulb, sternal posterior sigillae close to sternal margin and by the aspect of tibial apophysis which lacks the prolateral branch. Tmesiphantes presently comprises nine species. Sixth have been described for the southern region of Bahia, a well known area of endemism in the Atlantic Forest. Identification keys for Tmesiphantes males and females are presented

Taxonomy of the genus Cyrtopholis Simon, 1892 (Araneae, Mygalomorphae, Theraphosidae): Cuban species described by Pelegrín Franganillo Balboa

Fabiano-Da-Silva, Willian, Guadanucci, José Paulo Leite, Lucas, Giraldo Alayón Garcia Sylvia Marlene, Dasilva, Marcio Bernardino (2020): Taxonomy of the genus Cyrtopholis Simon, 1892 (Araneae, Mygalomorphae, Theraphosidae): Cuban species described by Pelegrín Franganillo Balboa. Zootaxa 4779 (1): 79-90, DOI: https://doi.org/10.11646/zootaxa.4779.1.

Response predictors and clinical benefits of hepatitis C retreatment with pegylated interferon and ribavirin in HIV/HCV coinfection

Background. Hepatitis C is a leading cause of mortality among HIV-infected individuals. Therefore, eradication of HCV in this population is a priority. There are scarce data regarding retreatment efficacy of HIV/ HCV coinfected patients. The aim of our study was to evaluate efficacy, predictors of response, and long term clinical benefits of sustained virological response (SVR) after hepatitis C retreatment in a population of HIV/HCV coinfected patients.Material and methods. We evaluated efficacy, safety, and clinical benefits of peginterferon(alfa-2a or alfa-2b) and ribavirin in a restrospective, observational, multicentric study, including 47 HIV/HCV coinfected patients, non-responders to previous treatment with conventional interferon alfa-2a and ribavirin. The primary endpoint of efficacy was SVR, defined as undetectable viral load 24 weeks after end of treatment. Death, liver disease progression, CD4 counts, and AIDS defining illness were the endpoints to access clinical benefits of treatment response.Results. In our analysis, 31.9% patients reached SVR. Genotypes 2/3 had a significant better SVR (66.7%) compared to genotypes 1/4 (33.3%) (p = 0.022). During follow-up, deaths (6.89%) and hepatic decompensation (28.6%) occurred only in the nonresponder group, while there were no cases of death or hepatic decompensation among the responder group(p = 0.037).Conclusion. Nearly one third of patients (mainly those with genotypes 2/3) reached SVR after hepatitis C retreatment in this group of HIV/HCV coinfected patients. SVR was protective against hepatic decompensation and death in a two-year follow-up period. Retreatment may be an effective and safe way to eradicate HCV until new anti-HCV drugs become available to this group of patients

Superoxide Production under Soft X-ray Irradiation of Liquid Water

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