Bioimpedance-based authentication of defrosted versus fresh pork at the end of refrigerated shelf life

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Developing Integrated Continuous Improvement Model for Competitiveness of Ethiopian Automotive Industry

The purpose of this study is to examine the relationship and difference among the continuous improvement tools such as just in time (JIT), total quality management (TQM), and lean six sigma (LSS). It also emphasizes these variable implementations and practices for competitiveness and achievement of integrated model development with common and unique success factors for a company's better competitiveness. Besides, it provides a case application evaluation of the model with the Bishoftu Automotive industry. Comparative study of TQM, JIT, LSS uses available literature critical analysis and knowledge of state of the art for competitive advantage. An in-depth analysis showed that a continuous improvement (CI) approach is necessary for the survival of industries in the dynamic and competitive market. Firms have employed CI strategies such as TQM, JIT, and LSS. However, most studies have demonstrated that factors concerning distinct approaches have advantages and limits in their situation. The integrated method would lead to the best competitive organization and resolve the shortcomings of each CI program. A thorough review of quality management (QM) methodology offers some possible explanations of why specific methods alone could not give an enterprise an absolute competitive advantage. This study, therefore, established an integrated model using the most commonly recognized variables by most research findings and practices. The research is exceptional in its scope by giving an insight into the advancement of CI and quality management in the context of an integrated model and introduced two new factors on existing CI factors

Developing Integrated Continuous Improvement Model for Competitiveness of Ethiopian Automotive Industry

The purpose of this study is to examine the relationship and difference among the continuous improvement tools such as just in time (JIT), total quality management (TQM), and lean six sigma (LSS). It also emphasizes these variable implementations and practices for competitiveness and achievement of integrated model development with common and unique success factors for a company's better competitiveness. Besides, it provides a case application evaluation of the model with the Bishoftu Automotive industry. Comparative study of TQM, JIT, LSS uses available literature critical analysis and knowledge of state of the art for competitive advantage. An in-depth analysis showed that a continuous improvement (CI) approach is necessary for the survival of industries in the dynamic and competitive market. Firms have employed CI strategies such as TQM, JIT, and LSS. However, most studies have demonstrated that factors concerning distinct approaches have advantages and limits in their situation. The integrated method would lead to the best competitive organization and resolve the shortcomings of each CI program. A thorough review of quality management (QM) methodology offers some possible explanations of why specific methods alone could not give an enterprise an absolute competitive advantage. This study, therefore, established an integrated model using the most commonly recognized variables by most research findings and practices. The research is exceptional in its scope by giving an insight into the advancement of CI and quality management in the context of an integrated model and introduced two new factors on existing CI factors

Beyond standard PSE testing: An exploratory study of bioimpedance as a marker for ham defects

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Beyond standard PSE testing: An exploratory study of bioimpedance as a marker for ham defects

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Service user involvement in mental health system strengthening in a rural African setting:qualitative study

Background: It is essential to involve service users in efforts to expand access to mental health care in integrated primary care settings in low- and middle-income countries (LMICs). However, there is little evidence from LMICs to guide this process. The aim of this study was to explore barriers to, and facilitators of, service user/caregiver involvement in rural Ethiopia to inform the development of a scalable approach.Methods: Thirty nine semi-structured interviews were carried out with purposively selected mental health service users (n = 13), caregivers (n = 10), heads of primary care facilities (n = 8) and policy makers/planners/service developers (n = 8). The interviews were audio-recorded and transcribed in Amharic, and translated into English. Thematic analysis was applied.Results: All groups of participants supported service user and caregiver involvement in mental health system strengthening. Potential benefits were identified as (i) improved appropriateness and quality of services, and (ii) greater protection against mistreatment and promotion of respect for service users. However, hardly any respondents had prior experience of service user involvement. Stigma was considered to be a pervasive barrier, operating within the health system, the local community and individuals. Competing priorities of service users included the need to obtain adequate individual care and to work for survival. Low recognition of the potential contribution of service users seemed linked to limited empowerment and mobilization of service users. Potential health system facilitators included a culture of community oversight of primary care services. All groups of respondents identified a need for awareness-raising and training to equip service users, caregivers, service providers and local community for involvement. Empowerment at the level of individual service users (information about mental health conditions, care and rights) and the group level (for advocacy and representation) were considered essential, alongside improved, accessible mental health care and livelihood interventions.Conclusion: As Ethiopia increases access to mental health care, a fundamental barrier to service user involvement is beginning to be addressed. Our study identified further barriers that need to be tackled, including a supportive political climate, and receptiveness amongst stakeholders. The findings will inform the development of a model of service user involvement, which will be piloted and evaluated

Utilization of growth monitoring and promotion services among children younger than 2 years in West Armachiho district, Northwest Ethiopia

IntroductionInadequate physical growth and poor development of children are prevalent and significant problems worldwide, with 149 million children younger than 5 years stunted and 49 million wasted. Growth monitoring and promotion (GMP) is one of the major activities implemented with the aim of capturing growth faltering before the child reaches the status of undernutrition. In relation to this, the Amhara region, where the study area is found, is a highly burdened area for child malnutrition. Thus, it needs further investigation about the utilization of GMP services and associated factors among children younger than 2 years in the study area.ObjectiveThe aim of this study was to assess the utilization of growth monitoring and promotion services and associated factors among children younger than 2 years.MethodsA community-based cross-sectional study was conducted in the West Armachiho district, including 703 mother–child pairs, with a response rate of 94.7%. A simple random sampling technique was used to select the respondents. Both bivariable and multivariable logistic regression analyzes were performed. An adjusted odds ratio (AOR) with a 95% confidence interval was used to measure the strength of the association.ResultsThe proportion of utilization of growth monitoring and promotion services in the West Armachiho district was 13.7% (95%Cl; 11.2, 16.4). Factors such as maternal educational status (AOR = 2.17, 95%Cl; 1.05, 4.49), institutional delivery (AOR = 3.16, 95%Cl; 1.62, 6.13), family size (AOR = 2.66, 95%Cl; 1.13, 6.23), access to health facility (AOR = 3.17, 95%Cl; 1.45, 6.95), and maternal knowledge (AOR = 4.53, 95%Cl; 2.71, 7.59) were significantly associated with the utilization of growth monitoring and promotion services.ConclusionUtilization of growth monitoring and promotion services in children younger than 2 years in the West Armachiho district was low. Thus, giving due attention to the improvement of the knowledge of the mothers/caregivers about child GMP services and counseling them about the importance of facility delivery is vital to improving growth monitoring and promotion services in the area

Polymorphism in killer cell immunoglobulin-like receptors and human leukocyte antigen-c and predisposition to preeclampsia in Ethiopian pregnant women population.

INTRODUCTION: Preeclampsia (PE) is a human specific pregnancy-related syndrome of unknown etiology that affects 2-8 % of pregnancies. Polymorphism in maternal Killer Cell Immunoglobulin-like Receptors (KIRs) and the ligand fetal Human Leukocyte Antigen-C (HLA-C) may predispose pregnant mothers for PE due to defective trophoblast invasion into the maternal decidua. Our study aimed to investigate the association between maternal KIR and fetal HLA-C polymorphism and PE in Ethiopian pregnant women. METHODS: We included a total of 288 (157 controls and 131 PE cases) in a case-controls study at Adama Regional Referral Hospital, Ethiopia. The KIR and HLA-C genotyping was done using traditional polymerase chain reaction on genomic DNA extracted form maternal venous and cord blood followed by 2% agarose gel electrophoresis. RESULTS: The statistical associations between variables were evaluated using Pearson's Chi-square test. P < 0.05, with 95 % confidence interval was considered statistically significant. A significant association was observed between the KIR2DS1 and PE, with a higher frequency (60.5 %) of the gene in the control group. Similarly, a significant association was observed between KIR AA genotype and PE, with a higher frequency (38.2 %) of this genotype in the PE group. Ethiopians share the same risk genotype for PE as seen in previous African and European studies, namely homozygosity of a maternal KIR AA genotype. However, Ethiopians differ from other East African populations by sharing the same protective KIR2DS1 gene as Europeans

Whole genome sequencing of Plasmodium vivax isolates reveals frequent sequence and structural polymorphisms in erythrocyte binding genes.

Plasmodium vivax malaria is much less common in Africa than the rest of the world because the parasite relies primarily on the Duffy antigen/chemokine receptor (DARC) to invade human erythrocytes, and the majority of Africans are Duffy negative. Recently, there has been a dramatic increase in the reporting of P. vivax cases in Africa, with a high number of them being in Duffy negative individuals, potentially indicating P. vivax has evolved an alternative invasion mechanism that can overcome Duffy negativity. Here, we analyzed single nucleotide polymorphism (SNP) and copy number variation (CNV) in Whole Genome Sequence (WGS) data from 44 P. vivax samples isolated from symptomatic malaria patients in southwestern Ethiopia, where both Duffy positive and Duffy negative individuals are found. A total of 123,711 SNPs were detected, of which 22.7% were nonsynonymous and 77.3% were synonymous mutations. The largest number of SNPs were detected on chromosomes 9 (24,007 SNPs; 19.4% of total) and 10 (16,852 SNPs, 13.6% of total). There were particularly high levels of polymorphism in erythrocyte binding gene candidates including merozoite surface protein 1 (MSP1) and merozoite surface protein 3 (MSP3.5, MSP3.85 and MSP3.9). Two genes, MAEBL and MSP3.8 related to immunogenicity and erythrocyte binding function were detected with significant signals of positive selection. Variation in gene copy number was also concentrated in genes involved in host-parasite interactions, including the expansion of the Duffy binding protein gene (PvDBP) on chromosome 6 and MSP3.11 on chromosome 10. Based on the phylogeny constructed from the whole genome sequences, the expansion of these genes was an independent process among the P. vivax lineages in Ethiopia. We further inferred transmission patterns of P. vivax infections among study sites and showed various levels of gene flow at a small geographical scale. The genomic features of P. vivax provided baseline data for future comparison with those in Duffy-negative individuals and allowed us to develop a panel of informative Single Nucleotide Polymorphic markers diagnostic at a micro-geographical scale

Remote sensing reveals how armed conflict regressed woody vegetation cover and ecosystem restoration efforts in Tigray (Ethiopia)

In recent years, armed conflicts are globally on the rise, causing drastic human and environmental harm. The Tigray war in Ethiopia is one of the recent violent conflicts that has abruptly reversed decades of ecosystem restoration efforts. This paper analyzes changes in woody vegetation cover during the period of armed conflict (2020–2022) using remote sensing techniques, supplemented by field testimony and secondary data. Extent of woody vegetation cover was analyzed using Normalized Difference Vegetation Index (NDVI) thresholding method from Sentinel 2 images in Google Earth Engine, and scale of de-electrification was qualitatively analyzed from Black Marble HD nighttime lights dataset, acquired from NASA's Black Marble team. The magnitude, direction as well as the mechanisms of change in woody vegetation cover varied across the region and over time. Tigray's woody vegetation cover fluctuated within 20% of the landmass. Mainly scattered to mountainous areas, the dry Afromontane forest cover declined from about 17% in 2020 to 15% in 2021, and 12% in 2022. About 17% of the overall decline was observed between 500 m and 2000 m elevation, where there is higher anthropogenic pressure. Land restoration practices meant to avert land degradation and desertification were interrupted and the area turned warfare ground. In many areas, forests were burned, the trees cut and the area became barren. The suspension of public services such as electricity for household or industrial use created heavy reliance on firewood and charcoal, further threatening to compound weather and climate. The magnitude of disturbance in a region that is already at a very high risk of desertification requires urgent national and international attention. Continued ecosystem disturbance could eventually make the domain part of a wider desert connecting the Sahel to the Afar Triangle, a scenario which may render the area uninhabitable.</p