854 research outputs found
How did business journalism outlets cover President Donald Trump's immigration ban using framing, hierarchical cluster analysis and a professional analysis at bloomberg news?
Professional project report submitted in partial fulfillment of the requirements for the degree of Masters of Arts in Journalism from the School of Journalism, University of Missouri--Columbia.The purpose of this project was to identify the ideologies behind each of the outlets' coverage of President Donald Trump's first immigration ban, through framing and a hierarchical cluster analysis. The analysis found that the two wires -- Bloomberg and Reuters -- produced by far the most content, yet Fox Business failed to produce a single piece of original content. This project intends to lay a foundation for future studies on how business journalism covers political news.Includes bibliographic references
Aphasia after Left Thalamic Infarction
We Examined a 70-Year-Old Woman Who Became Aphasic after a Left Thalamic Infarction. Computed Tomographic Scan Showed Injury that Was Largely Limited to the Ventral Anterior and Rostral Ventral Lateral Thalamic Nuclei. Speech Was Characterized by Reduced Voice Volume, Impaired Auditory and Reading Comprehension, Perseverations, Intermittent Use of Jargon, Fluctuations in the Ability to Perform Confrontation Naming, Extraneous Intrusions, Verbal Paraphasia, Intact Repetition Skills, and Fluent Speech that Was Laconic But Grammatically Correct. We Propose that the Deficits after Left Thalamic Injury Can Be Grouped into the Following Four Large Clusters: Extrapyramidal Deficits (Decreased or Fading Voice Volume), Deficits in Lexical Access (Anomia, Verbal Paraphasia), Deficits in Vigilance (Neologisms, Intrusions, Fluctuating Performance, Jargon, Perseverations), and Comprehension Defects. © 1984, American Medical Association. All Rights Reserved
Palliative psychiatry in a narrow and in a broad sense: A concept clarification
Even with optimal treatment, some persons with severe and persistent mental illness do not achieve a level of mental health, psychosocial functioning and quality of life that is acceptable to them. With each unsuccessful treatment attempt, the probability of achieving symptom reduction declines while the probability of somatic and psychological side effects increases. This worsening benefit-harm ratio of treatment aiming at symptom reduction has motivated calls for implementing palliative approaches to care into psychiatry (palliative psychiatry). Palliative psychiatry accepts that some cases of severe and persistent mental illness can be irremediable and calls for a careful evaluation of goals of care in these cases. It aims at reducing harm, relieving suffering and thus improving quality of life directly, working around irremediable psychiatric symptoms. In a narrow sense, this refers to patients likely to die of their severe and persistent mental illness soon, but palliative psychiatry in a broad sense is not limited to end-of-life care. It can - and often should - be integrated with curative and rehabilitative approaches, as is the gold standard in somatic medicine. Palliative psychiatry constitutes a valuable addition to established non-curative approaches such as rehabilitative psychiatry (which focuses on psychosocial functioning instead of quality of life) and personal recovery (a journey that persons living with severe and persistent mental illness may undertake, not necessarily accompanied by mental health care professionals). Although the implementation of palliative psychiatry is met with several challenges such as difficulties regarding decision-making capacity and prognostication in severe and persistent mental illness, it is a promising new approach in caring for persons with severe and persistent mental illness, regardless of whether they are at the end of life.
Keywords: Severe and persistent mental illness; end of life; futility; goals of care; irremediability; palliative psychiatry; quality of life; sufferin
Using Sentence Enhancements to Distinguish between Deterrence and Incapacitation
It is typically difficult to differentiate empirically between deterrence and incapacitation since both are a function of expected punishment. In this paper we demonstrate that the introduction of sentence enhancements (i.e. increased punishments that are added on to prison sentences that would have been served anyway) provides a direct means of measuring deterrence. Because the criminal would have been sentenced to prison anyway, there is no additional incapacitation effect from the sentence enhancement in the short-run. Therefore, any immediate decrease in crime must be due to deterrence. We test the model using California's Proposition 8 which imposed sentence enhancements for a selected group of crimes. In the year following its passage, crimes covered by Proposition 8 fell by more than 10 percent relative to similar crimes not affected by the law, suggesting a large deterrent effect. Three years after the law comes into effect, eligible crimes have fallen roughly 20-40 percent compared to non-eligible crimes. This large deterrent effect suggests that sentence enhancements, and may be more cost-effective than is generally thought.
Multimorbidity of communicable and non-communicable diseases in low- and middle-income countries: A systematic review
OBJECTIVE: The aim of this systematic review is to analyse existing evidence on prevalence, patterns, determinants, and healthcare challenges of communicable and non-communicable disease multimorbidity in low- and middle-income countries (LMICs). METHODS: PubMed, Cochrane, and Embase databases were searched from 1(st) January 2000 to 31(st) July 2020. The National Institute of Health (NIH) quality assessment tool was used to critically appraise studies. Findings were summarized in a narrative synthesis. The review was registered with PROSPERO (CRD42019133453). RESULTS: Of 3718 articles screened, 79 articles underwent a full text review of which 11 were included for narrative synthesis. Studies reported on 4 to 20 chronic communicable and non-communicable diseases; prevalence of multimorbidity ranged from 13% in a study conducted among 242,952 participants from 48 LMICS to 87% in a study conducted among 491 participants in South Africa. Multimorbidity was positively associated with older age, female sex, unemployment, and physical inactivity. Significantly higher odds of multimorbidity were noted among obese participants (OR 2.33; 95% CI: 2.19–2.48) and those who consumed alcohol (OR 1.44; 95% CI: 1.25–1.66). The most frequently occurring dyads and triads were HIV and hypertension (23.3%) and HIV, hypertension, and diabetes (63%), respectively. Women and participants from low wealth quintiles reported higher utilization of public healthcare facilities. CONCLUSION: The identification and prevention of risk factors and addressing evidence gaps in multimorbidity clustering is crucial to address the increasing communicable and non-communicable disease multimorbidity in LMICs. To identify communicable and non-communicable diseases trends over time and identify causal relationships, longitudinal studies are warranted
Protein dynamics with off-lattice Monte Carlo moves
A Monte Carlo method for dynamics simulation of all-atom protein models is
introduced, to reach long times not accessible to conventional molecular
dynamics. The considered degrees of freedom are the dihedrals at
C-atoms. Two Monte Carlo moves are used: single rotations about
torsion axes, and cooperative rotations in windows of amide planes, changing
the conformation globally and locally, respectively. For local moves Jacobians
are used to obtain an unbiased distribution of dihedrals. A molecular dynamics
energy function adapted to the protein model is employed. A polypeptide is
folded into native-like structures by local but not by global moves.Comment: 10 pages, 4 Postscript figures, uses epsf.sty and a4.sty; scheduled
tentatively for Phys.Rev.E issue of 1 March 199
The effect of spatial frequency on peripheral collinear facilitation
The detection of a Gabor patch (target) can be decreased or improved by the presence of co-oriented Gabor patches (flankers) having the same spatial frequency as the target. These phenomena are thought to be mediated by lateral interactions. Depending on the distance between target and flankers, commonly defined as a multiple of the wavelength (λ) of the carrier, flankers can increase or decrease a target's detectability. Studies with foveal presentation showed that for target-to-flankers distances 3λ contrast thresholds decrease. Earlier studies on collinear facilitation at the near-periphery of the visual field (4° of eccentricity) showed inconsistent facilitation (Shani & Sagi, 2005, Vision Research, 45, 2009-2024) whereas more recent studies showed consistent facilitation for larger separations (7-8λ) (Maniglia et al., 2011, PLoS ONE, 6, e25568; Lev & Polat, 2011, Vision Research, 51, 2488-2498). However, all of these studies used medium-to-high spatial frequencies (3-8cpd). In this study we tested lower spatial frequencies (1, 2, and 3cpd) with different target-to-flankers distances. The rationale was that near-peripheral vision is tuned for lower spatial frequencies and this could be reflected in collinear facilitation. Results show consistent collinear facilitation at 8λ for all the spatial frequencies tested, but also show collinear facilitation at shorter target-to-flanker distance (6λ) for the lowest spatial frequencies tested (1cpd). Additionally, collinear facilitation decreases as spatial frequency increases; opposite to the findings of Polat (2009, Spatial Vision, 22, 179-193) in the fovea, indicating a different spatial frequency tuning between foveal and peripheral lateral interactions
The organization of the transcriptional network in specific neuronal classes
Genome-wide expression profiling has aided the understanding of the molecular basis of neuronal diversity, but achieving broad functional insight remains a considerable challenge. Here, we perform the first systems-level analysis of microarray data from single neuronal populations using weighted gene co-expression network analysis to examine how neuronal transcriptome organization relates to neuronal function and diversity. We systematically validate network predictions using published proteomic and genomic data. Several network modules of co-expressed genes correspond to interneuron development programs, in which the hub genes are known to be critical for interneuron specification. Other co-expression modules relate to fundamental cellular functions, such as energy production, firing rate, trafficking, and synapses, suggesting that fundamental aspects of neuronal diversity are produced by quantitative variation in basic metabolic processes. We identify two transcriptionally distinct mitochondrial modules and demonstrate that one corresponds to mitochondria enriched in neuronal processes and synapses, whereas the other represents a population restricted to the soma. Finally, we show that galectin-1 is a new interneuron marker, and we validate network predictions in vivo using Rgs4 and Dlx1/2 knockout mice. These analyses provide a basis for understanding how specific aspects of neuronal phenotypic diversity are organized at the transcriptional level
Development and Launch of the World\u27s First Orbital Propellant Tanker
This paper describes the development of Orbit Fab’s Tanker-001 Tenzing mission, the world’s first orbital propellant tanker. The development of a robust orbital propellant supply chain is critical to accelerating the growth of government and commercial space activities. The widespread availability of spacecraft refueling has the potential to provide a number of revolutionary benefits. High-value space assets could have their operational lives extended, as they would no longer be constrained by the amount of propellant stored onboard for maneuvering. On-orbit servicing missions would become more efficient, as servicing vehicles could be refueled and repeatedly used. A large orbital propellant supply would also enable new mission and business models based on operational flexibility and frequent maneuvering. These benefits would be particularly impactful on small satellites, where the ability to refuel could overcome the operational constraints of having smaller propellant tanks. This will greatly expand the market for small spacecraft as it increases their range of missions and capabilities. Launching no earlier than June 24, 2021, Tenzing is a 35 kg small satellite with an Astro Digital bus carrying a supply of storable propellant, high test peroxide (HTP). Tenzing’s propellant supply is being offered to customers for refueling and used to gather data on propellant storage. In addition to being the first propellant tanker, Tenzing is also an orbital laboratory including a variety of payloads intended to test key technologies for refueling. This includes the first flight of Orbit Fab’s Rapidly Attachable Fluid Transfer Interface (RAFTI), a stereo camera system, and a Halcyon HTP propulsion system designed and built by Benchmark Space Systems for orbital maneuvers. The latter two elements can be used to test rendezvous and flyby maneuvers, providing data to support the development of full rendezvous, proximity operations, and docking (RPOD) systems for future Orbit Fab missions
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