550 research outputs found
Marketing Wine on the Web
E-commerce is penetrating agriculture, particularly for selling products directly to consumers. The wine industry is a case in point. The industry has long-term experience in direct marketing. Many wineries welcome patrons at their premises for wine tasting and for selling wine to them. Moreover, where the practice is allowed, shipping wine directly to consumers without the assistance of trade intermediaries is a significant sales channel. E-commerce was adopted early in the wine industries of wired high-income countries and the wine industry provides an opportunity for studying the adoption, use, and impact of e-commerce. Moreover, because e-commerce has not spread evenly through all branches of agriculture, lessons learned from the wine industry may provide useful insights for entrepreneurs and policy makers concerned with sections of agriculture or the food industry where e-commerce adoption lags behind. The specific objectives of the dissertation research project which we report here therefore were: (1) to assess the extent of e-commerce diffusion in the wine industries of Australia, California, Germany; (2) to identify e-commerce practices used by wineries for marketing wine; (3) to explain differences in wineries' e-commerce practices, and (4) to derive insights and implications for sections of agriculture that lag behind in ecommerce adoption.Marketing,
Preventing Suicide in Prisons, Part I Recommendations fromthe International Association for Suicide Prevention Task Force on Suicide in Prisons
Abstract. In 2000 the Department of Mental Health of the World Health Organization (WHO) published a guide named Preventing Suicide. A Resource for Prison Officers as part of the WHO worldwide initiative for the prevention of suicide. In 2007 there are new epidemiological data on prison suicide, a more detailed discussion of risk factors accounting for the generally higher rate of suicide in correctional settings in comparison to the general population, and several strategies for developing screening instruments. As a first step, this paper presents an update of the WHO guide by the Task Force on Suicide in Prisons, created by the International Association for Suicide Prevention. A second paper, by the same Task Force, will present some international comparisons of suicide prevention services in correctional facilities
A combined clinical and biomarker approach to predict diuretic response in acute heart failure
Background:
Poor diuretic response in acute heart failure is related to poor clinical outcome. The underlying mechanisms and pathophysiology behind diuretic resistance are incompletely understood. We evaluated a combined approach using clinical characteristics and biomarkers to predict diuretic response in acute heart failure (AHF).
Methods and results:
We investigated explanatory and predictive models for diuretic response—weight loss at day 4 per 40 mg of furosemide—in 974 patients with AHF included in the PROTECT trial. Biomarkers, addressing multiple pathophysiological pathways, were determined at baseline and after 24 h. An explanatory baseline biomarker model of a poor diuretic response included low potassium, chloride, hemoglobin, myeloperoxidase, and high blood urea nitrogen, albumin, triglycerides, ST2 and neutrophil gelatinase-associated lipocalin (r2 = 0.086). Diuretic response after 24 h (early diuretic response) was a strong predictor of diuretic response (β = 0.467, P < 0.001; r2 = 0.523). Addition of diuretic response after 24 h to biomarkers and clinical characteristics significantly improved the predictive model (r2 = 0.586, P < 0.001).
Conclusions:
Biomarkers indicate that diuretic unresponsiveness is associated with an atherosclerotic profile with abnormal renal function and electrolytes. However, predicting diuretic response is difficult and biomarkers have limited additive value. Patients at risk of poor diuretic response can be identified by measuring early diuretic response after 24 h
Photo-z optimization for measurements of the BAO radial direction
Baryon Acoustic Oscillations (BAO) in the radial direction offer a method to
directly measure the Universe expansion history, and to set limits to space
curvature when combined to the angular BAO signal. In addition to spectroscopic
surveys, radial BAO might be measured from accurate enough photometric
redshifts obtained with narrow-band filters. We explore the requirements for a
photometric survey using Luminous Red Galaxies (LRG) to competitively measure
the radial BAO signal and discuss the possible systematic errors of this
approach. If LRG were a highly homogeneous population, we show that the photo-z
accuracy would not substantially improve by increasing the number of filters
beyond , except for a small fraction of the sources detected at high
signal-to-noise, and broad-band filters would suffice to achieve the target
for measuring radial BAO. Using the LRG spectra
obtained from SDSS, we find that the spectral variability of LRG substantially
worsens the achievable photometric redshift errors, and that the optimal system
consists of 30 filters of width . A
is generally necessary at the filters on the red side of the
break to reach the target photometric accuracy. We estimate that a
5-year survey in a dedicated telescope with etendue in excess of 60 would be necessary to obtain a high enough density of galaxies to
measure radial BAO with sufficiently low shot noise up to . We
conclude that spectroscopic surveys have a superior performance than
photometric ones for measuring BAO in the radial direction.Comment: Replaced with minor editorial comments and one extra figure. Results
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Chaos in a double driven dissipative nonlinear oscillator
We propose an anharmonic oscillator driven by two periodic forces of
different frequencies as a new time-dependent model for investigating quantum
dissipative chaos. Our analysis is done in the frame of statistical ensemble of
quantum trajectories in quantum state diffusion approach. Quantum dynamical
manifestation of chaotic behavior, including the emergence of chaos, properties
of strange attractors, and quantum entanglement are studied by numerical
simulation of ensemble averaged Wigner function and von Neumann entropy.Comment: 9 pages, 18 figure
On Black Hole Scalar Hair in Asymptotically Anti de Sitter Spacetimes
The unexpected discovery of hairy black hole solutions in theories with
scalar fields simply by considering asymptotically Anti de-Sitter, rather than
asymptotically flat, boundary conditions is analyzed in a way that exhibits in
a clear manner the differences between the two situations.
It is shown that the trivial Schwarzschild Anti de Sitter becomes unstable in
some of these situations, and the possible relevance of this fact for the
ADS/CFT conjecture is pointed out.Comment: 12 pages. Published versio
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Validation of OMI Tropospheric NO2 Observations During INTEX-B and Application to Constrain NOx Emissions Over the Eastern United States and Mexico
We compare tropospheric NO2 column measurements from the Ozone Monitoring Instrument (OMI) aboard the EOS Aura satellite with coincident in situ aircraft measurements on vertical spirals over the southern United States, Mexico, and the Gulf of Mexico during the INTEX-B campaign in March 2006. Good correlation with no significant bias (r2=0.67, slope=0.99±0.17, n=12) is found for the ensemble of comparisons when the aircraft could spiral sufficiently low to sample most of the NO2 column. Urban spirals where large extrapolations were needed below the aircraft floor (1000 ft) showed poorer agreement. We use the OMI observations together with a global chemical transport model (GEOS-Chem) to estimate emissions of nitrogen oxides over the eastern United States and Mexico in March 2006. Comparison to EPA's National Emissions Inventory 1999 (NEI99) calls for a decrease in power plant emissions and an increase in on-road vehicle emissions relative to that inventory. The rise in vehicular emissions is offsetting the reduction in power plant and industry emissions. These findings are consistent with independent assessments. Our OMI-derived emission estimates for Mexico are higher by a factor of 2.0±0.5 than bottom-up emissions, similar to a comparison between the recently released Mexican NEI99 inventory and the bottom-up showing that the Mexican NEI99 inventory is 1.6–1.8× higher.Earth and Planetary SciencesEngineering and Applied Science
Transverse phase-locking in fully frustrated Josephson junction arrays: a new type of fractional giant steps
We study, analytically and numerically, phase locking of driven vortex
lattices in fully-frustrated Josephson junction arrays at zero temperature. We
consider the case when an ac current is applied {\it perpendicular} to a dc
current. We observe phase locking, steps in the current-voltage
characteristics, with a dependence on external ac-drive amplitude and frequency
qualitatively different from the Shapiro steps, observed when the ac and dc
currents are applied in parallel. Further, the critical current increases with
increasing transverse ac-drive amplitude, while it decreases for longitudinal
ac-drive. The critical current and the phase-locked current step width,
increase quadratically with (small) amplitudes of the ac-drive. For larger
amplitudes of the transverse ac-signal, we find windows where the critical
current is hysteretic, and windows where phase locking is suppressed due to
dynamical instabilities. We characterize the dynamical states around the
phase-locking interference condition in the curve with voltage noise,
Lyapunov exponents and Poincar\'e sections. We find that zero temperature
phase-locking behavior in large fully frustrated arrays is well described by an
effective four plaquette model.Comment: 12 pages, 11 figure
Allostatic self-efficacy: a metacognitive theory of dyshomeostasis-induced fatigue and depression
This paper outlines a hierarchical Bayesian framework for interoception, homeostatic/allostatic control, and meta-cognition that connects fatigue and depression to the experience of chronic dyshomeostasis. Specifically, viewing interoception as the inversion of a generative model of viscerosensory inputs allows for a formal definition of dyshomeostasis (as chronically enhanced surprise about bodily signals, or, equivalently, low evidence for the brain's model of bodily states) and allostasis (as a change in prior beliefs or predictions which define setpoints for homeostatic reflex arcs). Critically, we propose that the performance of interoceptive-allostatic circuitry is monitored by a metacognitive layer that updates beliefs about the brain's capacity to successfully regulate bodily states (allostatic self-efficacy). In this framework, fatigue and depression can be understood as sequential responses to the interoceptive experience of dyshomeostasis and the ensuing metacognitive diagnosis of low allostatic self-efficacy. While fatigue might represent an early response with adaptive value (cf. sickness behavior), the experience of chronic dyshomeostasis may trigger a generalized belief of low self-efficacy and lack of control (cf. learned helplessness), resulting in depression. This perspective implies alternative pathophysiological mechanisms that are reflected by differential abnormalities in the effective connectivity of circuits for interoception and allostasis. We discuss suitably extended models of effective connectivity that could distinguish these connectivity patterns in individual patients and may help inform differential diagnosis of fatigue and depression in the future
Did Patagonia collide with Gondwana in the Late Paleozoic? Some insights from a multidisciplinary study of magmatic units of the North Patagonian Massif
The origin of Patagonia and its relations with the South American crustal blocks to the north have been a matter of debate for decades. We report results from a multidisciplinary study centered on Paleozoic granitoids exposed in the northeastern corner of the North Patagonian Massif. Microstructural and magnetofabric studies reveal two suites of granitoids. Late Carboniferous (?) granitoids (Yaminué Complex, Tardugno Granodiorite, Cabeza de Vaca leucogranite) were emplaced and subsequently deformed in a major NNE-SSW compressive stress regime that also provoked top-to-the-SW thrust deformation in shallow crustal levels. Gravity and geobarometric studies show that the same major deformation event has been recorded at different crustal levels. The age and type of deformation of this event recorded across the northern boundary of Patagonia strongly supports a Late Carboniferous - Early Permian frontal collision between Patagonia and Gondwana. This major deformation event ceased by 281 Ma when the Navarrete Plutonic Complex, which shows mainly magmatic fabrics, was emplaced under a far-field WNW-ESE stress regime. Crustal continuity between the North Patagonian Massif and the Pampia and Arequipa- Antofalla terranes is suggested by similar Late Paleoproterozoic crustal model ages, comparable detrital zircon ages in Early Paleozoic successions, the apparent continuity of an Early Ordovician continental magmatic arc and paleomagnetic data. Reconciliation of this evidence with the Late Paleozoic frontal collision is obtained in a tectonic model that suggests that the North Patagonian Massif is a parautochthonous crustal block
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