Stewardship Plan Isinglass River Conservation Reserve, Strafford, NH

In addition to the significant frontage on the Isinglass River, the Hanson Lot supports myriad wetlands – vernal pools, beaver flowages, forested swamps, meadow marshes, and scrub-shrub wetlands. These are embedded within a hemlock – oak – beech - pine forest that was heavily logged in 1998. A plan to build a large 58- to 70-lot residential subdivision on the property was averted by the acquisition of the Hanson Lot as permanent conservation land. The Bedford property is also mostly wooded; the forest was carefully managed by previous owners and therefore retains a mix of tree species and ages. Together the properties are embedded within a 1,800-acre block of undeveloped lands that offers habitat for wide-ranging wildlife, protects water quality, and provides unique recreational experiences. A woods road runs through both properties, used by snowmobilers, hikers, mountain bikers, and horseback riders. The river corridor is a popular fishing destination

Louis H. Sullivan: that Object He Became

Louis H. Sullivan constructed a world view based on a hierarchy of powers. Over this hierarchy he placed the emotion of sympathy. Characterising it as another power he described sympathy as a way of being in communion with the world that manifests in a fusion of identities. Through a close reading of his writings with particular attention paid to his often-encrypted references to Walt Whitman, together with a close reading of selected sources from his library, this essay interrogates his understanding. Sensitive to the question of ‘queering’, it focuses on his conception of fused identities and its effects on gender and sexuality. It excavates an understanding that suggests that Sullivan deliberately constructed an alternative epistemology that overcame a whole host of bipolar oppositions to include male and female. He opted instead for an emotive and fluid ontology where the fixed category of being dissolves in vital consubstantiation – and it was eroticised. Suggesting a uniquely queer stance, Sullivan insists that without a clear vision of it, one may never understand architecture

Cartan subalgebras of root-reductive Lie algebras

Root-reductive Lie algebras are direct limits of finite-dimensional reductive Lie algebras under injections which preserve the root spaces. It is known that a root-reductive Lie algebra is a split extension of an abelian Lie algebra by a direct sum of copies of finite-dimensional simple Lie algebras as well as copies of the three simple infinite-dimensional root-reductive Lie algebras sl_infty, so_infty, and sp_infty. As part of a structure theory program for root-reductive Lie algebras, Cartan subalgebras of the Lie algebra gl_infty were introduced and studied in a paper of Neeb and Penkov. In the present paper we refine and extend the results of [N-P] to the case of a general root-reductive Lie algebra g. We prove that the Cartan subalgebras of g are the centralizers of maximal toral subalgebras and that they are nilpotent and self-normalizing. We also give an explicit description of all Cartan subalgebras of the simple Lie algebras sl_infty, so_infty, and sp_infty. We conclude the paper with a characterization of the set of conjugacy classes of Cartan subalgebras of the Lie algebras gl_infty, sl_infty, so_infty, and sp_infty with respect to the group of automorphisms of the natural representation which preserve the Lie algebra.Comment: 28 pages, 1 figur

A random walker on a ratchet

We analyze a model for a walker moving on a ratchet potential. This model is motivated by the properties of transport of motor proteins, like kinesin and myosin. The walker consists of two feet represented as two particles coupled nonlinearly through a bistable potential. In contrast to linear coupling, the bistable potential admits a richer dynamics where the ordering of the particles can alternate during the walking. The transitions between the two stable states on the bistable potential correspond to a walking with alternating particles. We distinguish between two main walking styles: alternating and no alternating, resembling the hand-over-hand and the inchworm walking in motor proteins, respectively. When the equilibrium distance between the two particles divided by the periodicity of the ratchet is an integer, we obtain a maximum for the current, indicating optimal transport.Comment: 10 pages, 5 figure

β2 Adrenergic receptor activation induces microglial NADPH oxidase activation and dopaminergic neurotoxicity through an ERK-dependent/protein kinase A-independent pathway

Activation of the β2 adrenergic receptor (β2AR) on immune cells has been reported to possess anti-inflammatory properties, however, the pro-inflammatory properties of β2AR activation remain unclear. In this study, using rat primary mesencephalic neuron-glia cultures, we report that salmeterol, a long-acting β2AR agonist, selectively induces dopaminergic (DA) neurotoxicity through its ability to activate microglia. Salmeterol selectively increased the production of reactive oxygen species (ROS) by NADPH oxidase (PHOX), the superoxide-producing enzyme in microglia. A key role of PHOX in mediating salmeterol-induced neurotoxicity was demonstrated by the inhibition of DA neurotoxicity in cultures pretreated with diphenylene-iodonium (DPI), an inhibitor of PHOX activity. Mechanistic studies revealed the activation of microglia by salmeterol results in the selective phosphorylation of ERK, a signaling pathway required for the translocation of the PHOX cytosolic subunit p47phox to the cell membrane. Furthermore, we found ERK inhibition, but not protein kinase A (PKA) inhibition, significantly abolished salmeterol-induced superoxide production, p47phox translocation, and its ability to mediate neurotoxicity. Together, these findings indicate that β2AR activation induces microglial PHOX activation and DA neurotoxicity through an ERK-dependent/PKA-independent pathway

WHOI Hawaii Ocean Timeseries Station (WHOTS) : WHOTS-10 2013 mooring turnaround cruise report

The Woods Hole Oceanographic Institution (WHOI) Hawaii Ocean Timeseries Site (WHOTS), 100 km north of Oahu, Hawaii, is intended to provide long-term, high-quality air-sea fluxes as a part of the NOAA Climate Observation Program. The WHOTS mooring also serves as a coordinated part of the Hawaii Ocean Timeseries (HOT) program, contributing to the goals of observing heat, fresh water and chemical fluxes at a site representative of the oligotrophic North Pacific Ocean. The approach is to maintain a surface mooring outfitted for meteorological and oceanographic measurements at a site near 22.75°N, 158°W by successive mooring turnarounds. These observations will be used to investigate air–sea interaction processes related to climate variability. This report documents recovery of the ninth WHOTS mooring (WHOTS-9) and deployment of the tenth mooring (WHOTS-10). Both moorings used Surlyn foam buoys as the surface element and were outfitted with two Air–Sea Interaction Meteorology (ASIMET) systems. Each ASIMET system measures, records, and transmits via Argos satellite the surface meteorological variables necessary to compute air–sea fluxes of heat, moisture and momentum. The upper 155 m of the moorings were outfitted with oceanographic sensors for the measurement of temperature, conductivity and velocity in a cooperative effort with R. Lukas of the University of Hawaii. A pCO2 system and ancillary sensors were installed on the buoys in cooperation with Chris Sabine at the Pacific Marine Environmental Laboratory. A set of radiometers were installed in cooperation with Sam Laney at WHOI. The WHOTS mooring turnaround was done on the NOAA ship Hi’ialakai by the Upper Ocean Processes Group of the Woods Hole Oceanographic Institution. The cruise took place between 9 and 16 July 2013. Operations began with deployment of the WHOTS-10 mooring on 10 July. This was followed by meteorological intercomparisons and CTDs. Recovery of the WHOTS-9 mooring took place on 14 July. This report describes these cruise operations, as well as some of the in-port operations and pre-cruise buoy preparations.Funding was provided by the National Oceanic and Atmospheric Administration under Grant. No. NA090AR4320129 and the Cooperative Institute for the North Atlantic Region (CINAR

Higher Education Exchange: 2012

This annual publication serves as a forum for new ideas and dialogue between scholars and the larger public. Essays explore ways that students, administrators, and faculty can initiate and sustain an ongoing conversation about the public life they share.The Higher Education Exchange is founded on a thought articulated by Thomas Jefferson in 1820: "I know no safe depository of the ultimate powers of the society but the people themselves; and if we think them not enlightened enough to exercise their control with a wholesome discretion, the remedy is not to take it from them, but to inform their discretion by education."In the tradition of Jefferson, the Higher Education Exchange agrees that a central goal of higher education is to help make democracy possible by preparing citizens for public life. The Higher Education Exchange is part of a movement to strengthen higher education's democratic mission and foster a more democratic culture throughout American society.Working in this tradition, the Higher Education Exchange publishes interviews, case studies, analyses, news, and ideas about efforts within higher education to develop more democratic societies

Economic growth, rural assets and prosperity: exploring the implications of a 20-year record of asset growth in Tanzania

Measures of poverty based on consumption suggest that recent economic growth in many African countries has not been inclusive, particularly in rural areas. We argue that measures of poverty using assets may provide a different picture. We present data based on recent re-surveys of Tanzanian households first visited in the early 1990s. These demonstrate a marked increase in prosperity from high levels of poverty. It does not, however, follow that these improvements derive from GDP growth. We consider the implications of this research for further explorations of the relationship between economic growth and agricultural policy in rural areas