8,098 research outputs found

    Fibre intake among the Belgian population by sex-age and sex-education groups and its association with BMI and waist circumference

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    The objectives of the present study were to assess total dietary fibre intake and the main contributors to fibre intake in the Belgian population by sex-age and sex-education groups and to investigate its relationship with BMI and waist circumference (WC). The participants of the Belgian food consumption survey (2004) were randomly selected. Information about food intake was collected using two repeated, non-consecutive 24 h recall interviews. A total of 3083 individuals (>= 15 years; 1546 men and 1537 women) completed both interviews. The main contributors to total fibre intake (17.8 g/d) were cereals and cereal products (34%; 5.9 g/d), potatoes and other tubers (18.6%; 3.3 g/d), fruits (14.7%; 2.8 g/d) and vegetables (14.4%; 2.6 g/d). Legume fibre intake was extremely low (0.672%; 0.139 g/d). In all sex-age and sex-education groups, total fibre intake was below the recommendations of the Belgian Superior Health Council. Men (21 g/d) consumed significantly more fibre than women (17.3 g/d) (P < 0.001). Lower educated men and higher educated women reported the highest fibre intake. A significant inverse association was found between total fibre intake and WC (beta = -0.118, P < 0.001). Fruit-derived fibre was positively associated with WC (beta = 0.731, P=0.001). In summary, total fibre intake was inversely associated with WC, whereas fruit-derived fibre intake was positively associated with WC in the Belgian population

    Pregnancy Associated Plasma Protein A2 (PAPP-A2) Affects Bone Size and Shape and Contributes to Natural Variation in Postnatal Growth in Mice

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    Pregnancy associated plasma protein A2 (PAPP-A2) is a protease of insulin-like growth factor binding protein 5 and is receiving increasing attention for its roles in pregnancy and postnatal growth. The goals of the present study were to characterize the effects of PAPP-A2 deletion on bone size and shape in mice at 10 weeks of age, and to determine whether Pappa2 is the gene responsible for a previously-identified quantitative trait locus (QTL) contributing to natural variation in postnatal growth in mice. Mice homozygous for constitutive PAPP-A2 deletion were lighter than wild-type littermates, and had smaller mandible dimensions and shorter skull, humerus, femur, tibia, pelvic girdle, and tail bone. Furthermore, PAPP-A2 deletion reduced mandible dimensions and the lengths of the skull, femur, pelvic girdle, and tail bone more than would be expected due to the effect on body mass. In addition to its effects on bone size, PAPP-A2 deficiency also altered the shape of the mandible and pelvic girdle, as assessed by geometric morphometrics. Mice homozygous for the PAPP-A2 deletion had less deep mandibles, and pelvic girdles with a more feminine shape. Using a quantitative complementation test, we confirmed that Pappa2 is responsible for the effects of the previously-identified QTL, demonstrating that natural variation in the Pappa2 gene contributes to variation in postnatal growth in mice. If similar functional variation in the Pappa2 gene exists in other species, effects of this variation on the shape of the pelvic girdle might explain the previously-reported associations between Pappa2 SNPs and developmental dysplasia of the hip in humans, and birthing in cattle

    Building integral projection models with non-independent vital rates

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    Population dynamics are functions of several demographic processes including survival, reproduction, somatic growth, and maturation. The rates or probabilities for these processes can vary by time, by location, and by individual. These processes can co‐vary and interact to varying degrees, e.g., an animal can only reproduce when it is in a particular maturation state. Population dynamics models that treat the processes as independent may yield somewhat biased or imprecise parameter estimates, as well as predictions of population abundances or densities. However, commonly used integral projection models (IPMs) typically assume independence across these demographic processes. We examine several approaches for modelling between process dependence in IPMs and include cases where the processes co‐vary as a function of time (temporal variation), co‐vary within each individual (individual heterogeneity), and combinations of these (temporal variation and individual heterogeneity). We compare our methods to conventional IPMs, which treat vital rates independent, using simulations and a case study of Soay sheep (Ovis aries). In particular, our results indicate that correlation between vital rates can moderately affect variability of some population‐level statistics. Therefore, including such dependent structures is generally advisable when fitting IPMs to ascertain whether or not such between vital rate dependencies exist, which in turn can have subsequent impact on population management or life‐history evolution

    Effect of Ordering on Spinodal Decomposition of Liquid-Crystal/Polymer Mixtures

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    Partially phase-separated liquid-crystal/polymer dispersions display highly fibrillar domain morphologies that are dramatically different from the typical structures found in isotropic mixtures. To explain this, we numerically explore the coupling between phase ordering and phase separation kinetics in model two-dimensional fluid mixtures phase separating into a nematic phase, rich in liquid crystal, coexisting with an isotropic phase, rich in polymer. We find that phase ordering can lead to fibrillar networks of the minority polymer-rich phase

    Fluctuating Hemiparesis Secondary to Moyamoya Phenomenon in a Child with Down Syndrome: a case report

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    Moyamoya phenomenon is a term used to describe extensive collateralization of the circle of Willis arteries associated with severe unilateral or bilateral internal carotid artery stenosis or occlusion in the presence of certain conditions. Down syndrome is among these conditions. A case is reported of a young girl with Down syndrome who presented with fluctuating right-sided weakness and facial droop found to have cerebral ischemia. Subsequent investigations disclosed characteristic "puff of smoke" patterns on angiographic studies consistent with moyamoya phenomenon. The patient was initially treated with aspirin and eventually underwent an encephalomyosynangiosis. This young patient with Down syndrome and moyamoya phenomenon serves as a reminder of the association between these two conditions

    Visualizations of Projected Rainfall Change in the United Kingdom: An Interview Study about User Perceptions

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    Stakeholders from public, private, and third sectors need to adapt to a changing climate. Communications about climate may be challenging, especially for audiences with limited climate expertise. Here, we study how such audience members perceive visualizations about projected future rainfall. In semi-structured interviews, we presented 24 participants from climate-conscious organizations across the UK with three prototypical visualizations about projected future rainfall, adopted from the probabilistic United Kingdom Climate Projections: (1) Maps displaying a central estimate and confidence intervals, (2) a line graph and boxplots displaying change over time and associated confidence intervals, and (3) a probability density function for distributions of rainfall change. We analyzed participants’ responses using “Thematic Analysis”. In our analysis, we identified features that facilitated understanding—such as colors, simple captions, and comparisons between different emission scenarios—and barriers that hindered understanding, such as unfamiliar acronyms and terminology, confusing usage of probabilistic estimates, and expressions of relative change in percentages. We integrate these findings with the interdisciplinary risk communication literature and suggest content-related and editorial strategies for effectively designing visualizations about uncertain climate projections for audiences with limited climate expertise. These strategies will help organizations such as National Met Services to effectively communicate about a changing climate

    Document Clustering Method Based on Frequent Co-occurring Words

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    PACLIC 20 / Wuhan, China / 1-3 November, 200

    Mid-Infrared Photometry and Spectra of Three High Mass Protostellar Candidates at IRAS 18151-1208 and IRAS 20343+4129

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    We present arcsecond-scale mid-ir photometry (in the 10.5 micron N band and at 24.8 microns), and low resolution spectra in the N band (R~100) of a candidate high mass protostellar object (HMPO) in IRAS 18151-1208 and of two HMPO candidates in IRAS 20343+4129, IRS 1 and IRS 3. In addition we present high resolution mid-ir spectra (R~80000) of the two HMPO candidates in IRAS 20343+4129. These data are fitted with simple models to estimate the masses of gas and dust associated with the mid-ir emitting clumps, the column densities of overlying absorbing dust and gas, the luminosities of the HMPO candidates, and the likely spectral type of the HMPO candidate for which [Ne II] 12.8 micron emission was detected (IRAS 20343+4129 IRS 3). We suggest that IRAS 18151-1208 is a pre-ultracompact HII region HMPO, IRAS 20343+4129 IRS 1 is an embedded young stellar object with the luminosity of a B3 star, and IRAS 20343+4129 IRS 3 is a B2 ZAMS star that has formed an ultracompact HII region and disrupted its natal envelope.Comment: 40 pages, 8 figures, 3 tables. Accepted for publication in Astrophysical Journal (Part 1
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