6,011 research outputs found

    Search for the standard model Higgs boson in the \hzzlepjet channel with the CMS experiment at LHC

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    A search for the standard model (SM) Higgs boson decaying into two Z bosons with a subsequent decay into two leptons and two quark jets, H → ZZ → + −q+q−, is presented. The data sample, corresponding to an integrated luminosity of 4.6 fb−1, is collected from proton proton collisions at the centre-of-mass energy of 7 TeV, with the CMS detector at the LHC at CERN, in proton-proton collisions at the centre-of-mass energy of 7 TeV. Discrimination of signal from background events is based on a kinematic selection and exploiting the different angular distribution of signal and background. No evidence for the Higgs boson is found, and upper limits on the Higgs boson production cross section are set between 130 and 600 GeV mass

    Microstructural White Matter Alterations in Men with Alcohol Use Disorder and Rats with Excessive Alcohol Consumption during Early Abstinence

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    Importance: Although the detrimental effects of alcohol on the brain are widely acknowledged, observed structural changes are highly heterogeneous, and diagnostic markers for characterizing alcohol-induced brain damage, especially in early abstinence, are lacking. This heterogeneity, likely contributed to by comorbidity factors in patients with alcohol use disorder (AUD), challenges a direct link of brain alterations to the pathophysiology of alcohol misuse. Translational studies in animal models may help bridge this causal gap. Objective: To compare microstructural properties extracted using advanced diffusion tensor imaging (DTI) in the brains of patients with AUD and a well-controlled rat model of excessive alcohol consumption and monitor the progression of these properties during early abstinence. Design, Setting, and Participants: This prospective observational study included 2 cohorts of hospitalized patients with AUD (n = 91) and Marchigian Sardinian alcohol-preferring (msP) rats (n = 27). In humans cross-sectional comparison were performed with control participants (healthy men [n = 36]) and longitudinal comparisons between different points after alcohol withdrawal. In rats, longitudinal comparisons were performed in alcohol-exposed (n = 27) and alcohol-naive msP rats (n = 9). Human data were collected from March 7, 2013, to August 3, 2016, and analyzed from June 14, 2017, to May 31, 2018; rat data were collected from January 15, 2017, to May 12, 2017, and analyzed from October 11, 2017, to May 28, 2018. Main Outcomes and Measures: Fractional anisotropy and other DTI measures of white matter properties after long-term alcohol exposure and during early abstinence in both species and clinical and demographic variables and time of abstinence after discharge from hospital in patients. Results: The analysis included 91 men with AUD (mean [SD] age, 46.1 [9.6] years) and 27 male rats in the AUD groups and 36 male controls (mean [SD] age, 41.7 [9.3] years) and 9 male control rats. Comparable DTI alterations were found between alcohol and control groups in both species, with a preferential involvement of the corpus callosum (fractional anisotropy Cohen d = -0.84 [P <.01] corrected in humans and Cohen d = -1.17 [P <.001] corrected in rats) and the fornix/fimbria (fractional anisotropy Cohen d = -0.92 [P <.001] corrected in humans and d = -1.24 [P <.001] corrected in rats). Changes in DTI were associated with preadmission consumption patterns in patients and progress in humans and rats during 6 weeks of abstinence. Mathematical modeling shows this process to be compatible with a sustained demyelination and/or a glial reaction. Conclusions and Relevance: Using a translational DTI approach, comparable white matter alterations were found in patients with AUD and rats with long-term alcohol consumption. In humans and rats, a progression of DTI alterations into early abstinence (2-6 weeks) suggests an underlying process that evolves soon after cessation of alcohol use

    Measurement of diffraction dissociation cross sections in pp collisions at s\sqrt{s} = 7 TeV

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    Measurements of diffractive dissociation cross sections in pp collisions at s√=7  TeV are presented in kinematic regions defined by the masses MX and MY of the two final-state hadronic systems separated by the largest rapidity gap in the event. Differential cross sections are measured as a function of ξX=M2X/s in the region −5.53, log10MX>1.1, and log10MY>1.1, a region dominated by DD. The cross sections integrated over these regions are found to be, respectively, 2.99±0.02(stat)+0.32−0.29(syst)  mb, 1.18±0.02(stat)±0.13(syst)  mb, and 0.58±0.01(stat)+0.13−0.11(syst)  mb, and are used to extract extrapolated total SD and DD cross sections. In addition, the inclusive differential cross section, dσ/dΔηF, for events with a pseudorapidity gap adjacent to the edge of the detector, is measured over ΔηF=8.4 units of pseudorapidity. The results are compared to those of other experiments and to theoretical predictions and found compatible with slowly rising diffractive cross sections as a function of center-of-mass energy

    Search for a pseudoscalar boson decaying into a ZZ boson and the 125 GeV Higgs boson in ℓ+ℓ−bbˉb\bar{b} final states

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    Results are reported on a search for decays of a pseudoscalar A boson into a ZZ boson and a light scalar h boson, where the Z boson decays into a pair of oppositely-charged electrons or muons, and the h boson decays into bbˉb\bar{b}. The search is based on data from proton–proton collisions at a center-of-mass energy s\sqrt{s}=8 TeV collected with the CMS detector, corresponding to an integrated luminosity of 19.7 fb1fb^{−1} . The h boson is assumed to be the standard model-like Higgs boson with a mass of 125 GeV. With no evidence for signal, upper limits are obtained on the product of the production cross section and the branching fraction of the A boson in the Zh channel. Results are also interpreted in the context of two Higgs doublet models

    Search for the standard model Higgs boson in the H to ZZ to 2l 2nu channel in pp collisions at sqrt(s) = 7 TeV

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    A search for the standard model Higgs boson in the H to ZZ to 2l 2nu decay channel, where l = e or mu, in pp collisions at a center-of-mass energy of 7 TeV is presented. The data were collected at the LHC, with the CMS detector, and correspond to an integrated luminosity of 4.6 inverse femtobarns. No significant excess is observed above the background expectation, and upper limits are set on the Higgs boson production cross section. The presence of the standard model Higgs boson with a mass in the 270-440 GeV range is excluded at 95% confidence level.Comment: Submitted to JHE

    Constraints on the χ_(c1) versus χ_(c2) polarizations in proton-proton collisions at √s = 8 TeV

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    The polarizations of promptly produced χ_(c1) and χ_(c2) mesons are studied using data collected by the CMS experiment at the LHC, in proton-proton collisions at √s=8  TeV. The χ_c states are reconstructed via their radiative decays χ_c → J/ψγ, with the photons being measured through conversions to e⁺e⁻, which allows the two states to be well resolved. The polarizations are measured in the helicity frame, through the analysis of the χ_(c2) to χ_(c1) yield ratio as a function of the polar or azimuthal angle of the positive muon emitted in the J/ψ → μ⁺μ⁻ decay, in three bins of J/ψ transverse momentum. While no differences are seen between the two states in terms of azimuthal decay angle distributions, they are observed to have significantly different polar anisotropies. The measurement favors a scenario where at least one of the two states is strongly polarized along the helicity quantization axis, in agreement with nonrelativistic quantum chromodynamics predictions. This is the first measurement of significantly polarized quarkonia produced at high transverse momentum
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