54 research outputs found
Arterial pO2 stimulates intimal hyperplasia and serum stimulates inward eutrophic remodeling in porcine saphenous veins cultured ex vivo
NADPH oxidases in cardiovascular disease: insights from in vivo models and clinical studies
NADPH oxidase family enzymes (or NOXs) are the major sources of reactive oxygen species (ROS) that are implicated in the pathophysiology of many cardiovascular diseases. These enzymes appear to be especially important in the modulation of redox-sensitive signalling pathways that underlie key cellular functions such as growth, differentiation, migration and proliferation. Seven distinct members of the family have been identified of which four (namely NOX1, 2, 4 and 5) may have cardiovascular functions. In this article, we review our current understanding of the roles of NOX enzymes in several common cardiovascular disease states, with a focus on data from genetic studies and clinical data where available
Wedded Bliss or Tainted Love? Stock Market Reactions to the Introduction of Cobranded Products
Cumulative π-π interaction triggers unusually high stabilization of linear hydrocarbons inside the single-walled carbon nanotube
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