Electrophysiological assessment methodology of sensory processing dysfunction in schizophrenia and dementia of the Alzheimer type

Schizophrenia and Alzheimer’s disease impacts on various sensory processings are extensively reviewed in the present publication. This article describes aspects of a research project whose aim is to delineate the neurobiology that may underlie Social Withdrawal in Alzheimer’s disease, Schizophrenia and Major Depression. This is a European-funded IMI 2 project, identified as PRISM (Psychiatric Ratings using Intermediate Stratified Markers). This paper focuses specifically on the selected electrophysiological paradigms chosen based on a comprehensive review of all relevant literature and practical constraints. The choice of the electrophysiological biomarkers were fundamentality based their metrics and capacity to discriminate between populations. The selected electrophysiological paradigms are resting state EEG, auditory mismatch negativity, auditory and visual based oddball paradigms, facial emotion processing ERP’s and auditory steady-state response. The primary objective is to study the effect of social withdrawal on various biomarkers and endophenotypes found altered in the target populations. This has never been studied in relationship to social withdrawal, an important component of CNS diseases

DairyBeef: Maximizing Quality and Profits—A Consistent Food Safety Message

To respond to meat safety and quality issues in dairy market cattle, a collaborative project team for 7 western states was established to develop educational resources providing a consistent meat safety and quality message to dairy producers, farm advisors, and veterinarians. The team produced an educational website and CD-ROM course that included videos, narrated slide sets, and on-farm tools. The objectives of this course were: 1) to help producers and their advisors understand market cattle food safety and quality issues, 2) help maintain markets for these cows, and 3) help producers identify ways to improve the quality of dairy cattle going to slaughter. DairyBeef: Maximizing Quality & Profits consists of 6 sections, including 4 core segments. Successful completion of quizzes following each core segment is required for participants to receive a certificate of completion. A formative evaluation of the program revealed the necessity for minor content and technological changes with the web-based course. All evaluators considered the materials relevant to dairy producers. After editing, course availability was enabled in February, 2003. Between February and May, 2003, 21 individuals received certificates of completion

A new wave of marine evidence-based management: emerging challenges and solutions to transform monitoring, evaluating, and reporting

Sustainable management and conservation of the world’s oceans requires effective monitoring, evaluation, and reporting (MER). Despite the growing political and social imperative for these activities, there are some persistent and emerging challenges that marine practitioners face in undertaking these activities. In 2015, a diverse group of marine practitioners came together to discuss the emerging challenges associated with marine MER, and potential solutions to address these challenges. Three emerging challenges were identified: (i) the need to incorporate environmental, social and economic dimensions in evaluation and reporting; (ii) the implications of big data, creating challenges in data management and interpretation; and (iii) dealing with uncertainty throughout MER activities. We point to key solutions to address these challenges across MER activities: (i) integrating models into marine management systems to help understand, interpret, and manage the environmental and socio-economic dimensions of uncertain and complex marine systems; (ii) utilizing big data sources and new technologies to collect, process, store, and analyze data; and (iii) applying approaches to evaluate, account for, and report on the multiple sources and types of uncertainty. These solutions point towards a potential for a new wave of evidence-based marine management, through more innovative monitoring, rigorous evaluation and transparent reporting. Effective collaboration and institutional support across the science–management–policy interface will be crucial to deal with emerging challenges, and implement the tools and approaches embedded within these solutions