1,621 research outputs found
Testing the Rule with Exclusive Semi-Leptonic Kaon Decays
We consider the possibility of violations of the selection rule at an appreciable level in {\it exclusive} semi-leptonic decays of
Kaons. At -Factories, intense Kaon beams will be available and will probe
among others, the semi-leptonic decays and in addition
to and could provide novel testing grounds for the
rule. In particular, the branching ratio of is non-negligible
and could be used to probe new phenomena associated with the violation of this
selection rule. Furthermore, we modify certain di-lepton event rate ratios and
asymmetries and time asymmetries that have been constructed by Dass and Sarma
for di-lepton events from Beon decays to test the at the
, to the Kaon system at the . We find that the large
width of the relative to that of plays an important role in
enhancing some of the time asymmetries.Comment: 10 pages, Plain Latex, To be run twice
Enhanced reaction kinetics in biological cells
The cell cytoskeleton is a striking example of "active" medium driven
out-of-equilibrium by ATP hydrolysis. Such activity has been shown recently to
have a spectacular impact on the mechanical and rheological properties of the
cellular medium, as well as on its transport properties : a generic tracer
particle freely diffuses as in a standard equilibrium medium, but also
intermittently binds with random interaction times to motor proteins, which
perform active ballistic excursions along cytoskeletal filaments. Here, we
propose for the first time an analytical model of transport limited reactions
in active media, and show quantitatively how active transport can enhance
reactivity for large enough tracers like vesicles. We derive analytically the
average interaction time with motor proteins which optimizes the reaction rate,
and reveal remarkable universal features of the optimal configuration. We
discuss why active transport may be beneficial in various biological examples:
cell cytoskeleton, membranes and lamellipodia, and tubular structures like
axons.Comment: 10 pages, 2 figure
SST-GATE: A dual mirror telescope for the Cherenkov Telescope Array
The Cherenkov Telescope Array (CTA) will be the world's first open
observatory for very high energy gamma-rays. Around a hundred telescopes of
different sizes will be used to detect the Cherenkov light that results from
gamma-ray induced air showers in the atmosphere. Amongst them, a large number
of Small Size Telescopes (SST), with a diameter of about 4 m, will assure an
unprecedented coverage of the high energy end of the electromagnetic spectrum
(above ~1TeV to beyond 100 TeV) and will open up a new window on the
non-thermal sky. Several concepts for the SST design are currently being
investigated with the aim of combining a large field of view (~9 degrees) with
a good resolution of the shower images, as well as minimizing costs. These
include a Davies-Cotton configuration with a Geiger-mode avalanche photodiode
(GAPD) based camera, as pioneered by FACT, and a novel and as yet untested
design based on the Schwarzschild-Couder configuration, which uses a secondary
mirror to reduce the plate-scale and to allow for a wide field of view with a
light-weight camera, e.g. using GAPDs or multi-anode photomultipliers. One
objective of the GATE (Gamma-ray Telescope Elements) programme is to build one
of the first Schwarzschild-Couder prototypes and to evaluate its performance.
The construction of the SST-GATE prototype on the campus of the Paris
Observatory in Meudon is under way. We report on the current status of the
project and provide details of the opto-mechanical design of the prototype, the
development of its control software, and simulations of its expected
performance.Comment: In Proceedings of the 33rd International Cosmic Ray Conference
(ICRC2013), Rio de Janeiro (Brazil). All CTA contributions at arXiv:1307.223
Kinetics of active surface-mediated diffusion in spherically symmetric domains
We present an exact calculation of the mean first-passage time to a target on
the surface of a 2D or 3D spherical domain, for a molecule alternating phases
of surface diffusion on the domain boundary and phases of bulk diffusion. We
generalize the results of [J. Stat. Phys. {\bf 142}, 657 (2011)] and consider a
biased diffusion in a general annulus with an arbitrary number of regularly
spaced targets on a partially reflecting surface. The presented approach is
based on an integral equation which can be solved analytically. Numerically
validated approximation schemes, which provide more tractable expressions of
the mean first-passage time are also proposed. In the framework of this minimal
model of surface-mediated reactions, we show analytically that the mean
reaction time can be minimized as a function of the desorption rate from the
surface.Comment: Published online in J. Stat. Phy
Impact of Acute Kidney Injury and CKD on Adverse Outcomes in Critically Ill Septic Patients
Introduction: Chronic kidney disease (CKD) and acute kidney injury (AKI) are strongly associated with excess morbidity and mortality and frequently co-occur in critically ill septic patients, but how their interplay affects clinical outcomes is not well elucidated. Methods: We conducted a single-center, retrospective cohort study of 2632 adult patients admitted to the intensive care unit (ICU) with severe sepsis or septic shock. Subjects were classified into 6 groups according to baseline CKD (no-CKD: estimated glomerular filtration rate [eGFR] ≥60; CKD: eGFR 15−59 ml/min per 1.73 m2) and incident AKI by the Kidney Disease: Improving Global Outcomes (KDIGO) serum creatinine criteria (no-AKI, AKI stage 1, AKI stages ≥2) during ICU stay. Study outcomes were 90-day mortality (in hospital or within 90 days of discharge) and incident/progressive CKD. Results: Prevalent CKD was 46% and incident AKI was 57%. Adjusted hazard ratios (95% confidence intervals) for 90-day mortality relative to the reference group of no-CKD/no-AKI were 1.5 (1.1−2.0) in no-CKD/AKI stage 1, 2.4 (1.9−3.1) in no-CKD/AKI stages≥2, 1.1 (0.8−1.4) in CKD/no-AKI, 1.2 (0.9−1.6) in CKD/AKI stage 1, and 2.2 (1.7−2.9) in CKD/AKI stages ≥2. A similar trend was observed for incident/progressive CKD during a median follow-up of 15.3 months. Conclusion: Stage 1 AKI on CKD was not associated with an independent increased risk of adverse outcomes in critically ill septic patients. AKI stages ≥2 on CKD and any level of AKI in no-CKD patients were strongly and independently associated with adverse outcomes. Sepsis-associated stage 1 AKI on CKD may represent distinct underlying pathophysiology, with more prerenal cases and less severe de novo intrinsic damage, which needs further investigation
The finite temperature real time \hbar^2 corrections in quantum mechanics
We study non-perturbative real time correlation functions at finite
temperature. In order to see whether the classical term gives a good
approximation in the high temperature limit T >> \hbar\omega, we consider the
first \hbar^2 quantum corrections. We find that for the simplest non-trivial
case, the quantum mechanical anharmonic oscillator, the classical result is
reliable only for moderately large times: after some time t_* the classical
approximation breaks down even at high temperatures. Moreover, the result for
the first quantum corrections cannot, in general, be reproduced by modifying
the parameters of the classical theory.Comment: 28 pages, 7 figure
GYES, a multifibre spectrograph for the CFHT
We have chosen the name of GYES, one of the mythological giants with one
hundred arms, offspring of Gaia and Uranus, for our instrument study of a
multifibre spectrograph for the prime focus of the Canada-France-Hawaii
Telescope. Such an instrument could provide an excellent ground-based
complement for the Gaia mission and a northern complement to the HERMES project
on the AAT. The CFHT is well known for providing a stable prime focus
environment, with a large field of view, which has hosted several imaging
instruments, but has never hosted a multifibre spectrograph. Building upon the
experience gained at GEPI with FLAMES-Giraffe and X-Shooter, we are
investigating the feasibility of a high multiplex spectrograph (about 500
fibres) over a field of view 1 degree in diameter. We are investigating an
instrument with resolution in the range 15000 to 30000, which should provide
accurate chemical abundances for stars down to 16th magnitude and radial
velocities, accurate to 1 km/s for fainter stars. The study is led by
GEPI-Observatoire de Paris with a contribution from Oxford for the study of the
positioner. The financing for the study comes from INSU CSAA and Observatoire
de Paris. The conceptual study will be delivered to CFHT for review by October
1st 2010.Comment: Contributed talk at the Gaia ELSA conference 2010, S\`evres 7-11 June
2010, to be published on the EAS Series, Editors: C. Turon, F. Arenou & F.
Meynadie
Spectroscopic survey of the Galaxy with Gaia I. Design and performance of the Radial Velocity Spectrometer
The definition and optimisation studies for the Gaia satellite spectrograph,
the Radial Velocity Spectrometer (RVS), converged in late 2002 with the
adoption of the instrument baseline. This paper reviews the characteristics of
the selected configuration and presents its expected performance. The RVS is a
2.0 by 1.6 degree integral field spectrograph, dispersing the light of all
sources entering its field of view with a resolving power R=11 500 over the
wavelength range [848, 874] nm. The RVS will continuously and repeatedly scan
the sky during the 5 years of the Gaia mission. On average, each source will be
observed 102 times over this period. The RVS will collect the spectra of about
100-150 million stars up to magnitude V~17-18. At the end of the mission, the
RVS will provide radial velocities with precisions of ~2 km/s at V=15 and
\~15-20 km/s at V=17, for a solar metallicity G5 dwarf. The RVS will also
provide rotational velocities, with precisions (at the end of the mission) for
late type stars of sigma_vsini ~5 km/s at V~15 as well as atmospheric
parameters up to V~14-15. The individual abundances of elements such as Silicon
and Magnesium, vital for the understanding of Galactic evolution, will be
obtained up to V~12-13. Finally, the presence of the 862.0 nm Diffuse
Interstellar Band (DIB) in the RVS wavelength range will make it possible to
derive the three dimensional structure of the interstellar reddening.Comment: 17 pages, 9 figures, accepted for publication in MNRAS. Fig. 1,2,4,5,
6 in degraded resolution; available in full resolution at
http://blackwell-synergy.com/links/doi/10.1111/j.1365-2966.2004.08282.x/pd
Irreversible Quantum Mechanics in the Neutral K-System
The neutral Kaon system is used to test the quantum theory of resonance
scattering and decay phenomena. The two dimensional Lee-Oehme-Yang theory with
complex Hamiltonian is obtained by truncating the complex basis vector
expansion of the exact theory in Rigged Hilbert space. This can be done for K_1
and K_2 as well as for K_S and K_L, depending upon whether one chooses the
(self-adjoint, semi-bounded) Hamiltonian as commuting or non-commuting with CP.
As an unexpected curiosity one can show that the exact theory (without
truncation) predicts long-time 2 pion decays of the neutral Kaon system even if
the Hamiltonian conserves CP.Comment: 36 pages, 1 PostScript figure include
- …