205 research outputs found

    Rheological study of structural transitions in triblock copolymers in a liquid crystal solvent

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    Rheological properties of triblock copolymers dissolved in a nematic liquid crystal (LC) solvent demonstrate that their microphase separated structure is heavily influenced by changes in LC order. Nematic gels were created by swelling a well-defined, high molecular weight ABA block copolymer with the small-molecule nematic LC solvent 4-pentyl-4-cyanobiphenyl (5CB). The B midblock is a side-group liquid crystal polymer (SGLCP) designed to be soluble in 5CB and the A endblocks are polystyrene, which is LC-phobic and microphase separates to produce a physically cross-linked, thermoreversible, macroscopic polymer network. At sufficiently low polymer concentration a plateau modulus in the nematic phase, characteristic of a gel, abruptly transitions to terminal behavior when the gel is heated into its isotropic phase. In more concentrated gels, endblock aggregates persist into the isotopic phase. Dramatic changes in network structure are observed over small temperature windows (as little as 1 °C) due to tccche rapidly changing LC order near the isotropization point. The discontinuous change in solvent quality produces an abrupt change in viscoelastic properties for three polymers having different pendant mesogenic groups and matched block lengths

    Constant-Time Communication for Information Retrieval Systems

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    The construction of write-ahead logging is a robust grand challenge. In fact, few biologists would disagree with the synthesis of RPCs, demonstrates the intuitive importance of steganography. In our research we show not only that the foremost virtual algorithm for the de- velopment of Scheme is in Co-NP, but that the same is true for suffix trees

    Neonatal infrared thermography images in the hypothermic ruminant model: Anatomical-morphological-physiological aspects and mechanisms for thermoregulation

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    Hypothermia is one factor associated with mortality in newborn ruminants due to the drastic temperature change upon exposure to the extrauterine environment in the first hours after birth. Ruminants are precocial whose mechanisms for generating heat or preventing heat loss involve genetic characteristics, the degree of neurodevelopment at birth and environmental aspects. These elements combine to form a more efficient mechanism than those found in altricial species. Although the degree of neurodevelopment is an important advantage for these species, their greater mobility helps them to search for the udder and consume colostrum after birth. However, anatomical differences such as the distribution of adipose tissue or the presence of type II muscle fibers could lead to the understanding that these species use their energy resources more efficiently for heat production. The introduction of unconventional ruminant species, such as the water buffalo, has led to rethinking other characteristics like the skin thickness or the coat type that could intervene in the thermoregulation capacity of the newborn. Implementing tools to analyze species-specific characteristics that help prevent a critical decline in temperature is deemed a fundamental strategy for avoiding the adverse effects of a compromised thermoregulatory function. Although thermography is a non-invasive method to assess superficial temperature in several non-human animal species, in newborn ruminants there is limited information about its application, making it necessary to discuss the usefulness of this tool. This review aims to analyze the effects of hypothermia in newborn ruminants, their thermoregulation mechanisms that compensate for this condition, and the application of infrared thermography (IRT) to identify cases with hypothermia

    Investigación e impacto de materiales

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    A través de este proyecto, se buscó desarrollar e implementar metodologías que evalúen y generen la información que describe el desempeño de las empresas productoras de materiales, como consecuencia de su falta de regulación. Lo anterior, se logró a través de dos líneas de trabajo: una ecoetiqueta que permita certificar a las empresas mexicanas luego de la evaluación del impacto ambiental generado en las etapas del ciclo de vida de un material en específico y una base de datos que permite conocer las distintas opciones de materiales que cumplan las características necesarias para el producto deseado. Esto se logró con la con ayuda de las normas y leyes mexicanas, así como de las EPD’s internacionales y la metodología de Ashby. Finalmente, se obtuvo como resultado del proyecto cinco entregables: ECOMAT y su correspondiente manual de usuario, las metodologías necesarias para el acercamiento y seguimiento de empresas, un formato interno tipo EPD para los materiales de Materioteca ITESO, un formato mejorado de la ficha física de Materioteca ITESO y una base de datos de los tipos de materiales dentro de ésta última.ITESO, A.C

    The neurobiology of pain and facial movements in rodents: clinical applications and current research

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    One of the most controversial aspects of the use of animals in science is the production of pain. Pain is a central ethical concern. The activation of neural pathways involved in the pain response has physiological, endocrine, and behavioral consequences, that can aect both the health and welfare of the animals, as well as the validity of research. The strategy to prevent these consequences requires understanding of the nociception process, pain itself, and how assessment can be performed using validated, non-invasive methods. The study of facial expressions related to pain has undergone considerable study with the finding that certain movements of the facial muscles (called facial action units) are associated with the presence and intensity of pain. This review, focused on rodents, discusses the neurobiology of facial expressions, clinical applications, and current research designed to better understand pain and the nociceptive pathway as a strategy for implementing refinement in biomedical research.Adriana Domínguez-Oliva, Daniel Mota-Rojas, Ismael Hernández-Avalos, Patricia Mora-Medina, Adriana Olmos-Hernández, Antonio Verduzco-Mendoza, Alejandro Casas-Alvarado, and Alexandra L. Whittake

    ACCIÓN INHIBITORIA DE PROBIÓTICOS SOBRE EL CRECIMIENTO AXÉNICO IN VITRO DEEntamoeba histolytica

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    Entamoeba histolytica es el protozoario parásito cosmopolita causante de la amibiasis y sus múltiples manifestaciones clínicas afectando con mayor frecuencia a los países en vías de desarrollo en donde existe hacinamiento y condiciones sanitarias deficientes e inadecuadas; en México representa un problema de saludpública por su frecuencia, morbilidad, mortalidad y fácil dispersión; para el control de la amibiasis y sus manifestaciones clínicas, se administra metronidazol como droga de elección, sin embargo este fármaco produce efectos secundarios indeseables. Reportes recientes indican que cultivos in vitro de E. histolytica han desarrollado resistencia a este fármaco. En este trabajo evaluamos el efecto de 1, 10, 20 y 100 mg/mL de liofilizados de medios condicionados con probióticos (Lactobacillus acidophilus, Lactobacillus casei y Lactococcus lactis) sobre el crecimiento axénico in vitro de E. histolytica. Las concentraciones ensayadas mostraron diferencia estadística significativa (ANOVA p=0.05) como inhibidores del crecimiento in vitro de Entamoeba histolytica HM1-IMSS. Estos resultados abren la posibilidad de contar con una alternativa nutricional para la prevención y tratamiento de la amibiasis sin presentar efectos secundarios indeseables.Palabras claves: Entamoeba histolytica, Lactobacillus acidophilus, Lactobacillus casei, Lactococcus lactis, cultivo axénico, probióticos.Entamoeba histolytica, Lactobacillus acidophilus, Lactobacillus casei, Lactococcus lactis, axenic culture, probiotics

    Optimal Design of a Trickle Bed Reactor for Light Fuel Oxidative Desulfurization based on Experiments and Modelling

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    YesIn this work, the performance of oxidative desulfurization (ODS) of dibenzothiophene (DBT) in light gas oil (LGO) is evaluated with a homemade manganese oxide (MnO2/γ-Al2O3) catalyst. The catalyst is prepared by Incipient Wetness Impregnation (IWI) method with air under moderate operating conditions. The effect of different reaction parameters such as reaction temperature, liquid hour space velocity and initial concentration of DBT are also investigated experimentally. Developing a detailed and a validated trickle bed reactor (TBR) process model that can be employed for design and optimization of the ODS process, it is important to develop kinetic models for the relevant reactions with high accuracy. Best kinetic model for the ODS process taking into account hydrodynamic factors (mainly, catalyst effectiveness factor, catalyst wetting efficiency and internal diffusion) and the physical properties affecting the oxidation process is developed utilizing data from pilot plant experiments. An optimization technique based upon the minimization of the sum of the squared error between the experimental and predicted composition of oxidation process is used to determine the best parameters of the kinetic models. The predicted product conversion showed very good agreement with the experimental data for a wide range of the operating condition with absolute average errors less than 5%
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