The Metallicity and Reddening of Stars in the Inner Galactic Bulge

We present a preliminary analysis of K, J-K color magnitude diagrams (CMDs) for 7 different positions on or close to the minor axis of the Milky Way at Galactic latitudes between +0.1^\circ and -2.8^\circ. From the slopes of the (linear) giant branches in these CMDs we derive a dependence of on latitude for b between -0.8^\circ and -2.8^\circ of -0.085 \pm 0.033 dex/degree. When combined with the data from Tiede et al. we find for -0.8^\circ \leq b \leq -10.3^\circ the slope in is -0.064 \pm 0.012 dex/degree. An extrapolation to the Galactic Center predicts [Fe/H] = +0.034 \pm 0.053 dex. We also derive average values for the extinction in the K band (A_K) of between 2.15 and 0.27 for the inner bulge fields corresponding to average values of E(J-K) of between 3.46 and 0.44. There is a well defined linear relation between the average extinction for a field and the star-to-star scatter in the extinction for the stars within each field. This result suggests that the typical apparent angular scale size for an absorbing cloud is small compared with the field size (90\arcsec on a side). Finally, from an examination of the luminosity function of bright giants in each field we conclude that the young component of the stellar population observed near the Galactic center declines in density much more quickly than the overall bulge population and is undetectable beyond 1^\circ from the Galactic center.Comment: accepted for publication in Astron. Jour. Compressed file contains the text, 9 figures, and 6 tables prepared with AAS Latex macros v. 4.

Automated parameterisation for multi-scale image segmentation on multiple layers

AbstractWe introduce a new automated approach to parameterising multi-scale image segmentation of multiple layers, and we implemented it as a generic tool for the eCognition® software. This approach relies on the potential of the local variance (LV) to detect scale transitions in geospatial data. The tool detects the number of layers added to a project and segments them iteratively with a multiresolution segmentation algorithm in a bottom-up approach, where the scale factor in the segmentation, namely, the scale parameter (SP), increases with a constant increment. The average LV value of the objects in all of the layers is computed and serves as a condition for stopping the iterations: when a scale level records an LV value that is equal to or lower than the previous value, the iteration ends, and the objects segmented in the previous level are retained. Three orders of magnitude of SP lags produce a corresponding number of scale levels. Tests on very high resolution imagery provided satisfactory results for generic applicability. The tool has a significant potential for enabling objectivity and automation of GEOBIA analysis

Implications of New JHK Photometry and a Deep Infrared Luminosity Function for the Galactic Bulge

We present deep near-IR photometry for Galactic bulge stars in Baade's Window, $(l,b) = (1.0\deg, -3.9\deg),$ and another minor axis field at $(l,b) = (0^\circ,-6^\circ)$. We combine our data with previously published photometry and construct a luminosity function over the range $5.5 \leq K_0 \leq 16.5$, deeper than any previously published. The slope of this luminosity function and the magnitude of the tip of the first ascent giant branch are consistent with theoretical values derived from isochrones with appropriate age and metallicity. We use the relationship between [Fe/H] and the giant branch slope derived from near-IR observations of metal rich globular clusters by Kuchinski {\it et al.} [AJ, 109, 1131 (1995)] to calculate the mean metallicity for several bulge fields along the minor axis. For Baade's Window we derive $\langle {\rm[Fe/H]}\rangle = -0.28 \pm 0.16$, consistent with the recent estimate of McWilliam \& Rich [ApJS, 91, 749 (1994)], but somewhat lower than previous estimates based on CO and TiO absorption bands and the $JHK$ colors of M giants by Frogel {\it et al.} [ApJ, 353, 494 (1990)]. Between $b = -3\deg$ and $-12\deg$ we find a gradient in $\langle {\rm [Fe/H]}\rangle$ of $-0.06 \pm 0.03$ dex/degree or $-0.43 \pm 0.21$ dex/kpc for $R_0 = 8$ kpc, consistent with other independent derivations. We derive a helium abundance for Baade's Window with the $R$ and $R^\prime$ methods and find that $Y = 0.27 \pm 0.03$ implying $\Delta Y / \Delta Z = 3.3 \pm 1.3$. Next, we find that the bolometric corrections for bulge K giants ($V - K \leq 2$) are in excellent agreement with empirical derivations based on observations of globular cluster and local field stars. However, for the redder M giants weComment: Accepted by the Astronomical Journal. 43 pages, uuencoded compressed PostScript, no figures or tables. A complete (text, figs and tables) preprint is also available at ftp://bessel.mps.ohio-state.edu/pub/terndrup/bwphot.tar.Z (compressed tar file with PostScript

Novel parameters for evaluating the Spatial and Thematic accuracy of land cover maps.

Se proponen novedosas fórmulas para evaluar la certeza de la cartografí

Vimentin expression influences flow dependent VASP phosphorylation and regulates cell migration and proliferation

The cytoskeleton plays a central role for the integration of biochemical and biomechanical signals across the cell required for complex cellular functions. Recent studies indicate that the intermediate filament vimentin is necessary for endothelial cell morphogenesis e.g. in the context of leukocyte transmigration. Here, we present evidence, that the scaffold provided by vimentin is essential for VASP localization and PKG mediated VASP phosphorylation and thus controls endothelial cell migration and proliferation. Vimentin suppression using siRNA technique significantly decreased migration velocity by 50% (videomicroscopy), diminished transmigration activity by 42.5% (Boyden chamber) and reduced proliferation by 43% (BrdU-incorporation). In confocal microscopy Vimentin colocalized with VASP and PKG in endothelial cells. Vimentin suppression was accompanied with a translocation of VASP from focal contacts to the perinuclear region. VASP/Vimentin and PKG/Vimentin colocalization appeared to be essential for proper PKG mediated VASP phosphorylation because we detected a diminished expression of PKG and p(Ser239)-VASP in vimentin-suppressed cells, Furthermore, the induction of VASP phosphorylation in perfused arteries was markedly decreased in vimentin knockout mice compared to wildtypes. A link is proposed between vimentin, VASP phosphorylation and actin dynamics that delivers an explanation for the important role of vimentin in controlling endothelial cell morphogenesis

Antibody mimetic receptor proteins for label-free biosensors

The development of high sensitivity biosensors, for example for clinical diagnostics, requires the identification of suitable receptor molecules which offer high stability, specificity and affinity, even when embedded into solid-state biosensor transducers. Here, we present an electrochemical biosensor employing small synthetic receptor proteins (Mw < 15 kDa) which emulate antibodies but with improved stability, sensitivity and molecular recognition properties, in particular when immobilized on a solid sensor surface. The synthetic receptor protein is a non-antibody-based protein scaffold with variable peptide regions inserted to provide the specific binding, and was designed to bind anti-myc tag antibody (Mw � 150 kDa), as a proof-of-principle exemplar. Both the scaffold and the selected receptor protein were found to have high thermostability with melting temperatures of 101 �C and 85 �C, respectively. Furthermore, the secondary structures of the receptor protein were found to be very similar to that of the original native scaffold, despite the insertion of variable peptide loops that create the binding sites. A label-free electrochemical sensor was fabricated by functionalising a microfabricated gold electrode with the receptor protein. A change in the phase of the electrochemical impedance was observed when the biosensor was subjected to anti-myc tag antibodies at concentrations between 6.7 pM and 6.7 nM. These findings demonstrate that these non-antibody receptor proteins are excellent candidates for recognition molecules in label-free biosensors

Bayesian Accretion Modeling: Axisymmetric Equatorial Emission in the Kerr Spacetime

The Event Horizon Telescope (EHT) has produced images of two supermassive black holes, Messier~87* (M 87*) and Sagittarius~A* (Sgr A*). The EHT collaboration used these images to indirectly constrain black hole parameters by calibrating measurements of the sky-plane emission morphology to images of general relativistic magnetohydrodynamic (GRMHD) simulations. Here, we develop a model for directly constraining the black hole mass, spin, and inclination through signatures of lensing, redshift, and frame dragging, while simultaneously marginalizing over the unknown accretion and emission properties. By assuming optically thin, axisymmetric, equatorial emission near the black hole, our model gains orders of magnitude in speed over similar approaches that require radiative transfer. Using 2017 EHT M 87* baseline coverage, we use fits of the model to itself to show that the data are insufficient to demonstrate existence of the photon ring. We then survey time-averaged GRMHD simulations fitting EHT-like data, and find that our model is best-suited to fitting magnetically arrested disks, which are the favored class of simulations for both M 87* and Sgr A*. For these simulations, the best-fit model parameters are within ${\sim}10\%$ of the true mass and within ${\sim}10^\circ$ for inclination. With 2017 EHT coverage and 1\% fractional uncertainty on amplitudes, spin is unconstrained. Accurate inference of spin axis position angle depends strongly on spin and electron temperature. Our results show the promise of directly constraining black hole spacetimes with interferometric data, but they also show that nearly identical images permit large differences in black hole properties, highlighting degeneracies between the plasma properties, spacetime, and most crucially, the unknown emission geometry when studying lensed accretion flow images at a single frequency.Comment: Accepted to ApJ, 16 pages, 10 figure

Study of damage control systems for space station

Damage control systems for detecting and locating overboard and onboard leak and damage modes on space station