Impact of Fii in recent stock market volatility / D. S. Selvakumar

The growth of relationship of interdependence between individuals and institutions across geographical and political boundaries through globalisation leads to increase of flow of investments capital. Globalisation refers to a process of increasing economic integration and growing economic interdependence between countries in the world economy. For a developing country, opening up of the stock market to FII can act as catalyst in improving efficiency of the market. As FII arrival is associated with the importation of sophisticated financial technology, adoption of the technology to the domestic environment, and greater investments in improving information processing and financial services. However these benefits should be weighted against uncertainties associated with opening up of the market. One of the major concerns is that the portfolio funds may lead to greater volatility in domestic stock prices. If foreign stock prices for any reason fluctuate the domestic prices will also respond to the fluctuations. This paper focuses on the impact of FIIs in the stock market volatility in recent times

Factors associated with glycemic control in children with type 1 diabetes mellitus.

Type I diabetes mellitus is a chronic metabolic disorder with heterogeneous etiologies characterized by hyperglycemia as a cardinal biochemical feature. Patients with Diabetes mellitus are at increased risk of morbidity and mortality due to the micro and macrovascular complication caused by diabetes. Maintaining strict glycemic control in type I DM reduces the incidence and progression of long term complication. There are various risk factors found to be associated with poor glycemic control. Identification of risk factors associated with poor glycemic control is necessary, so that appropriate intervention can be done to improve glycemic control and to prevent complication. As there is a lack of regional literature, this study was undertaken in our setting. Aims and Objectives To study the factors associated of glycemic control in Type I Diabetes Children. Materials and Methods This is a cross sectional study carried out at the diabetes clinic for children at tertiary care hospital ICH & HC in Chennai. Children attending the clinic were enrolled into the study after obtaining informed consent from the parent / guardian. A structured questionnaire was used to collect date from the parents/guardian. Glycemic Control was assessed by measurement of glycosylated Hb .Data entry and analysis was done using Epi Info Software Version 3.5.1 and SPSS version 16. Results 99 participants were recruited into the study. The mean HbA1C was 9.16% (SD2.168) came under a fair control group. 31 children had age appropriate glycemic control. The children with good glycemic control had a statistically significant level of hypoglycemic p=0.041. 53 children presented with DKA as initial onset of diabetes mellitus. 21 children were hospitalized for inter current illness. Conclusion The following factors namely age, duration of diabetes, insulin regimen, SMBG, compliance to therapy, follow up and serum cholesterol did not have impact on glycemic control. Hypo glycemic episodes were found to be more common in children with good glycemic control which was statistically significant

Improvement of oil content in groundnut (Arachis hypogaea L.) by the impacts of gamma irradiation

Gamma radiation dosages of 100, 200, 300, 400, 500 and 600 Gy were given to the groundnut seed variety Dharani (Arachis hypogaea L.). The study's goal was to look at genetic diversity, heritability and genetic advancement for seed yield and quality characteristics in M2 generation using only a Randomized Complete Block Experiment using 3 replications from 2018 to 2019. The article's outcomes significantly enhanced the oil content of groundnut at 400 Gy to 52.44 % as compared to other dosages. For all characteristics, treated seeds displayed more variance than control seeds, particularly seed yield per plant showing the highest in GCV, PCV, H2, GA and GAM. In most traits, 400 Gy of gamma-ray treatment generates the largest changes however, 600 Gy of gamma-ray treatment also creates equivalent conditions. The link between features demonstrated that the number of pods per plant had a significant role in rationalizing seed yield variance in the M2 generation. These findings show that this yield component is one of the most important predictors of pod yield variations among plants and it is also favorably impacted by irradiation mutagens (gamma rays)

Control system of automatic garage using programmable logic controller

In today’s populated world, urban land availability has become scarce and manual involvement of humans for a proper task makes a work less efficient and less accurate. The garage is one of the workstations which needs to be modernized for enhanced land utilization, energy saving approach and systematic functioning. This goal can only be achieved through the automation of parking systems. We have proposed an automated control system for garage using siemens PLC (programmable logic control)-1200 to control the vehicles. The number plate of the car is recorded through the RFID reader and the parking slot for that particular vehicle is allotted automatically based on the available vacancy. Along with this the parking area is fitted with fire alarm, which will raise if any smoke or fire happens in the location. The total parking cost of each vehicle can be calculated based on the number of hours it has been parked. And the information will be displayed in the SCADA screen. Additionally, instead of the full lightening of the complete place, lightening will be provided only in the direction of movement of the car, preventing wastage of energy

Formulation development and evaluation of regio-selective bilayer floating tablets of propranolol for sustained release and rosuvastatin calcium for immediate release

The present study was aimed to develop regio-selective bilayer floating tablets containing propranolol hydrochloride as SR layer and Rosuvastatin calcium as IR layer for hypertensive patients. Combination therapy of beta-blocker and HMGCo-A Reductase inhibitors is recommended for treatment of hypertensive patients. The drug excipient interaction was investigated with FTIR spectroscopy. The study indicated that there was no interaction between the drug and the excipients used in the formulations. The floating matrix layer was formulated with hydrophobic polymer (ethyl cellulose) and hydrophilic polymers (HPMC K4M, HPMC K100 and Xanthan gum) to retard the drug release upto 12 hours. The rosuvastatin calcium solid dispersion of different ratios (1:1, 1:2, 1:3, and 1:4) was prepared by taking starch phosphate as a novel carrier for the drug. From the dissolution results of rosuvastatin solid dispersion, two ratios which exhibit enhanced dissolution of rosuvastatin calcium were selected. The immediate release rosuvastatin calcium layer was formulated with sodium starch glycolate (4%). All the formulations were evaluated for physical characteristics, drug content, dissolution, release kinetics and stability studies. The tablets were formulated by wet granulation method because the flow property of the drugs and the blends were poor. The formulated granules were evaluated and showed good flow property. The tablets were found to be within the limits with respect to uniformity of weight, hardness, thickness, diameter and friability. The disintegration time of the IR tablets containing solid dispersion in ratio of 1:4 and SSG 4 % was found to be optimum. The drug content of the formulated IR tablets was found to be within the limits. The invitro dissolution studies were performed for all the IR-SD formulations. The formulations RC-1, RC-2 and RC-3 released 46.05, 77.79 and 101.29 at the end of 15 minutes. Thus the formulation RC-3 has enhanced solubility of rosuvastatin calcium and it was optimized formulation and selected for compression with bilayer floating tablets. The drug content of the formulated Propranolol hydrochloride SR floating tablets was found to be within Pharmacopoeial limits. The drug content of the bilayer floating tablets was estimated by simultaneous estimation method and it was found to be within Pharmacopoeial limits. In vitro dissolution studies were performed for all the bilayer floating tablet formulations. The formulation RBFT-7 containing HPMC K4M 20% Released the drug upto 12 hours. Floating lag time of bilayer floating tablets was within 3 minutes and floating duration was more than 12 hours. In vitro dissolution study was performed for bilayer floating tablets. At the end of 15 minutes the release was found to be 101.29% for immediate release layer of Rosuvastatin calcium and at the end of 12th hour the release was found to be 101.01 % for sustained release layer of Propranolol hydrochloride. Release kinetics of sustained release layer of bilayer floating tablets followed zero order release kinetics. The release of the drug was dependent on diffusion, swelling and erosion of the polymer. The stability studies showed that the formulated bilayer floating tablets were stable and did not show any significant changes in the physical characteristics, drug content and dissolution. The results obtained were found to be within acceptable limits. Thus the formulated bilayer floating tablets of propranolol hydrochloride and rosuvastatin calcium was found to be stable. Regio- selective bilayer floating tablets of rosuvastatin calcium for immediate release and propranolol hydrochloride for sustained release was formulated to reduce the frequency of administration and to reduce hypertension

Effect of osmotic stress on in vitro plant growth hormone production by osmotolerant bacteria isolated from chilli phyto microbiome

The present study was conducted to determine the effect of osmotic stress on the plant growth hormone production by six osmotolerant plant growth promoting bacterial strains. These strains originated from the phytomicrobiome of chilli cultivated in the drought prone areas of Andhra Pradesh. They possessed multiple plant growth promotion traits including the ability to produce a variety of plant growth hormones. The effect of osmotic stress on the plant growth hormone production was determined by High Performance Liquid Chromatography (HPLC) under normal and in vitro osmotic stress conditions using 25% Poly Ethylene Glycol (PEG) 8000. In general, it was observed that osmotic stress impacted the plant growth hormone production of the isolates, but nevertheless plant hormones were detected in all the bacterial strains. An exception to this was the cytokinin molecule zeatin riboside, which was produced at higher levels by five of the six bacterial isolates under osmotic stressed conditions

A Sub-Region Based Space Vector Modulation Scheme for Dual 2-Level Inverter System

This paper deals the implementation of 3-level output voltage using dual 2-level inverter with control of sub-region based Space Vector Modulation (SR-SVM). Switching loss and voltage stress are the most important issues in multilevel inverters, for keep away from these problems dual inverter system executed. Using this proposed system, the conventional 3-level inverter voltage vectors and switching vectors can be located. In neutral point clamped multilevel inverter, it carries more load current fluctuations due to the DC link capacitors and it requires large capacitors. Based on the sub-region SVM used to control IGBT switches placed in the dual inverter system. The proposed system improves the output voltage with reduced harmonic content with improved dc voltage utilisation. The simulation and hardware results are verified using matlab/simulink and dsPIC microcontroller

Experimental investigation and mechanism analysis: Effect of concentration and temperature on the heat transfer characteristics of novel MWCNT-mustard oil nanofluid

ABSTRACT. The bio-oils as alternative lubricating fluid are potential solution for the automotive and industrial mechanical systems. The development of novel renewable and non-toxic bio-oils with better heat transfer distinctiveness will strengthen the economy of farmers in the agricultural based countries. The most innovative approach to improve the heat transfer characteristics of bio-oils is converting it into nanofluids by dispersing nanomaterials which has extremely high heat transfer characteristics. In this study, MWCNT-Mustard oil nanofluids were formulated through ultrasonication and their dispersion stability was estimated through Zeta-potential technique.  The thermal stability of the MWCNT-Mustard oil nanofluids are estimated through thermogravimetric analysis and concentration and temperature dependent density, thermal conductivity and specific heat capacity of MWCNT-Mustard oil nanofluids are also determined and their characteristics are discussed. The heat transfer characteristics of MWCNT-Mustard oil nanofluids observed through the heat pipe test rig at different inlet temperatures, mass flow rate of nanofluids and Reynolds number. The results exhibits that the dispersion of MWCNT enhances the heat transfer characteristics of MWCNT-Mustard oil nanofluids.   KEY WORDS: Non-toxic bio-oils, Nanomaterials, Nanofluids, Thermogravimetric analysis, MWCNT, Mustard oil Bull. Chem. Soc. Ethiop. 2022, 36(3), 675-686.                                                                DOI: https://dx.doi.org/10.4314/bcse.v36i3.1

The Mycobacterium marinum mel2 locus displays similarity to bacterial bioluminescence systems and plays a role in defense against reactive oxygen and nitrogen species

BACKGROUND: Mycobacteria have developed a number of pathways that provide partial protection against both reactive oxygen species (ROS) and reactive nitrogen species (RNS). We recently identified a locus in Mycobacterium marinum, mel2, that plays a role during infection of macrophages. The molecular mechanism of mel2 action is not well understood. RESULTS: To better understand the role of the M. marinum mel2 locus, we examined these genes for conserved motifs in silico. Striking similarities were observed between the mel2 locus and loci that encode bioluminescence in other bacterial species. Since bioluminescence systems can play a role in resistance to oxidative stress, we postulated that the mel2 locus might be important for mycobacterial resistance to ROS and RNS. We found that an M. marinum mutant in the first gene in this putative operon, melF, confers increased susceptibility to both ROS and RNS. This mutant is more susceptible to ROS and RNS together than either reactive species alone. CONCLUSION: These observations support a role for the M. marinum mel2 locus in resistance to oxidative stress and provide additional evidence that bioluminescence systems may have evolved from oxidative defense mechanisms