Type I diabetes mellitus is a chronic metabolic disorder with
heterogeneous etiologies characterized by hyperglycemia as a cardinal
biochemical feature. Patients with Diabetes mellitus are at increased risk
of morbidity and mortality due to the micro and macrovascular
complication caused by diabetes. Maintaining strict glycemic control in
type I DM reduces the incidence and progression of long term
complication. There are various risk factors found to be associated with
poor glycemic control. Identification of risk factors associated with poor
glycemic control is necessary, so that appropriate intervention can be
done to improve glycemic control and to prevent complication. As there
is a lack of regional literature, this study was undertaken in our setting.
Aims and Objectives
To study the factors associated of glycemic control in Type I
Diabetes Children.
Materials and Methods
This is a cross sectional study carried out at the diabetes clinic for
children at tertiary care hospital ICH & HC in Chennai. Children
attending the clinic were enrolled into the study after obtaining informed
consent from the parent / guardian. A structured questionnaire was used
to collect date from the parents/guardian. Glycemic Control was assessed
by measurement of glycosylated Hb .Data entry and analysis was done
using Epi Info Software Version 3.5.1 and SPSS version 16.
Results
99 participants were recruited into the study. The mean HbA1C
was 9.16% (SD2.168) came under a fair control group. 31 children had
age appropriate glycemic control. The children with good glycemic
control had a statistically significant level of hypoglycemic p=0.041. 53
children presented with DKA as initial onset of diabetes mellitus.
21 children were hospitalized for inter current illness.
Conclusion
The following factors namely age, duration of diabetes, insulin
regimen, SMBG, compliance to therapy, follow up and serum cholesterol
did not have impact on glycemic control. Hypo glycemic episodes were
found to be more common in children with good glycemic control which
was statistically significant
