Efficient continuous collision detection for bounding boxes under rational motion

This paper presents a simple yet precise and efficient algorithm for collision prediction of two oriented bounding boxes under univariate (piecewise) rational motion. We present an analytic solution to the problem of finding the time of collision and the feature involved, or declaring that no collision should occur. Our solution can be applied to boxes of any size, under arbitrary rational rigid motion. The algorithm is based on the efficient examination of the Minkowski sum (MS) of the two boxes, using a spherical Gauss map dual representation, and a precise extraction of the collision time, if any, as a solution to a set of rational equations that are automatically derived. © 2006 IEEE.published_or_final_versio

Introducing GLUSEEN: A New Open Access and Experimental Network in Urban Soil Ecology

Peer reviewe

Insecticide resistance and the future of malaria control in Zambia.

BACKGROUND: In line with the Global trend to improve malaria control efforts a major campaign of insecticide treated net distribution was initiated in 1999 and indoor residual spraying with DDT or pyrethroids was reintroduced in 2000 in Zambia. In 2006, these efforts were strengthened by the President's Malaria Initiative. This manuscript reports on the monitoring and evaluation of these activities and the potential impact of emerging insecticide resistance on disease transmission. METHODS: Mosquitoes were captured daily through a series of 108 window exit traps located at 18 sentinel sites. Specimens were identified to species and analyzed for sporozoites. Adult Anopheles mosquitoes were collected resting indoors and larva collected in breeding sites were reared to F1 and F0 generations in the lab and tested for insecticide resistance following the standard WHO susceptibility assay protocol. Annual cross sectional household parasite surveys were carried out to monitor the impact of the control programme on prevalence of Plasmodium falciparum in children aged 1 to 14 years. RESULTS: A total of 619 Anopheles gambiae s.l. and 228 Anopheles funestus s.l. were captured from window exit traps throughout the period, of which 203 were An. gambiae malaria vectors and 14 An. funestus s.s.. In 2010 resistance to DDT and the pyrethroids deltamethrin, lambda-cyhalothrin and permethrin was detected in both An. gambiae s.s. and An. funestus s.s.. No sporozoites were detected in either species. Prevalence of P. falciparum in the sentinel sites remained below 10% throughout the study period. CONCLUSION: Both An. gambiae s.s. and An. funestus s.s. were controlled effectively with the ITN and IRS programme in Zambia, maintaining a reduced disease transmission and burden. However, the discovery of DDT and pyrethroid resistance in the country threatens the sustainability of the vector control programme

Quantifying Long-Term Urban Grassland Dynamics: Biotic Homogenization and Extinction Debts

Sustainable urban nature conservation calls for a rethinking of conventional approaches. Traditionally, conservationists have not incorporated the history of the landscape in management strategies. This study shows that extant vegetation patterns are correlated to past landscapes indicating potential extinction debts. We calculated urban landscape measures for seven time periods (1938–2019) and correlated it to three vegetation sampling events (1995, 2012, 2019) using GLM models. We also tested whether urban vegetation was homogenizing. Our results indicated that urban vegetation in our study area is not currently homogenizing but that indigenous forb species richness is declining significantly. Furthermore, long-term studies are essential as the time lags identified for different vegetation sampling periods changed as well as the drivers best predicting these changes. Understanding these dynamics are critical to ensuring sustainable conservation of urban vegetation for future citizens

The effectiveness of axial flow fans in a-frame plenums

Thesis (PhD (Mechanical and Mechatronic Engineering)--University of Stellenbosch, 1990.ENGLISH ABSTRACT: The ultimate goal of this project is to ensure a better understanding of the governing mechanisms present when flow distorting components are installed in close proximity of an axial flow fan. The effect of different parameters on the operation of axial flow fans is investigated. These parameters are divided into flow enhancing and flow reduction effects. The performance of an axial flow fan can be enhanced by changing the tip clearance, by adding a solid disc to the hub of the fan or by varying the number of fan blades. Flow reductions are caused by components such as inlet grids, walkways and their supporting structures, heat exchangers and windwalls. The effects of flow enhancing components are measured and compared to the results of other authors. The sensitivity of these effects to parameters such as the type of fan rotor and the specific system in which the rotor is installed is highlighted. The system effect (the interaction between the fan rotor and flow resistances in close proximity of each other) of individual components, as well as the combination of different components, is predicted both theoretically and experimentally. These predictions are compared to measured data relevant to the components in an installation where the system effects are present. The results are correlated to the kinetic energy flux coefficient of the flow at different locations within the installation. Experimental data obtained from a full scale unit (inlet shroud diameter of 9,216 m) are used to compare to scaled data from the model (inlet shroud diameter of 1,542 m). The hub to tip ratio of the axial flow fans investigated is 0,15. The most important conclusions are that the performance of the type of axial flow fan under investigation can be improved by reducing its tip clearance and by installing a solid disc to the downstream side of the rotor. An increase in the number of blades of the fan leads to only marginal improvements in the fan performance. The overall performance of the system can also be improved by removing some of the flow resisting components, or by changing their relative positions. All these conclusions are based on the assumption that the power input to the fan rotor remains constant.AFRIKAANSE OPSOMMING: Die uiteindelike doel van hierdie projek is om te verseker dat die beherende meganismes wat teenwoordig is wanneer vloeiversteurende komponente in die nabyheid van 'n aksiaalwaaier geinstalleer word, beter verstaan word. Die effek van verskillende parameters op die werkverrigting van aksiaalwaaiers word ondersoek. Hierdie parameters word verdeel in vloeiverbeterings- en vloeiverminderingseffekte. Die werkverrigting van 'n aksiaalwaaier kan verbeter word deur die lempuntspeling te verstel, deur 'n soliede skyf aan die naaf van die waaierrotor te installeer, of deur die aantal lemme te verander. Die vloeiverminderings word veroorsaak deur inlaatsiwwe, loopvlakke en hul ondersteuningsstrukture, warmteruilers en windwande. Die effekte van vloeiverbeteringskomponente word gemeet en vergelyk met die resultate van ander outeurs. Die sensitiwiteit van hierdie effekte op parameters soos die tipe rotor en die spesifieke stelsel waarin die rotor geinstalleer is, word uitgelig. Die stelseleffek (die interaksie tussen die rotor van die waaier en vloei weerstande wat naby mekaar geinstalleer is) van individuele, sowel as 'n kombinasie van verskillende komponente, word teoreties en eksperimenteel voorspel. Hierdie voorspellings word dan vergelyk met eksperimentele data wat van toepassing is op die komponente in 'n installasie waar stelseleffekte voorkom. Die resultate word gekoppel aan die kinetiese energievloedkoeffisient van die vloei by verskillende posisies binne die installasie. Eksperimentele data, verkry vanaf 'n volskaaleenheid (inlaatmondstukdiameter van 9,216 m), word met die geskaleerde data van die model (inlaatmondstukdiameter van 1,542 m) vcrgelyk. Die naaf- tot hulsverhouding van die aksiaalwaaiers wat ondersoek word is 0,15. Die belangrikste gevolgtrekkings is dat die werkverrigting van die tipe aksiaalwaaier wat ondersoek word verbeter kan word deur die lempuntspeling te verminder en deur 'n soliede skyf te installeer by die stroomaf kant van die rotor. 'n Toename in die aantal lemme van die waaier lei slegs tot marginale verbeterings in die werkverrigting van die waaier. Die totale werkverrigting van die stesel kan ook verbeter word deur sommige vloeiweerstandskomponente te verwyder, of deur hulle relatiewe posisies te verander. Al hierdie gevolgtrekkings is gebasseer op die aanname dat die drywingsinset na die waaierrotor konstant bly.260 leaves printed single pages, preliminary pages i-xxi and numbered pages Chapter 1/1.1-1.3, Chapter 2/2.1-2.17, Chapter 3/3.1.1-3.10, Chapter 4/4.1-4.18, Chapter 5/5.1-5.3, References pages R.1-R.7, Appendix A pages A.1-A.34, Appendix B pages B.1-B.34, Appendix C pages C.1-C.26, Appendix D pages D.1-D.16, Appendix E pages E.1-E.30, Appendix F pages F.1-F.39. Includes bibliography, list of tables, figures and symbols

Earthworm assemblages in urban habitats across biogeographical regions

In urban landscapes, humans are the most significant factor determining belowground diversity, including earthworms. Within the framework of the Global Urban Soil Ecology and Education Network (GLUSEEN), a multi-city comparison was carried out to assess the effects of soil disturbance on earthworms. In each of five cities (Baltimore, USA; Budapest, Hungary; Helsinki and Lahti, Finland; Potchefstroom, South Africa), covering four climatic and biogeographical regions, four habitat types (ruderal, turf/lawn, remnant and reference) were sampled. The survey resulted in 19 species belonging to 9 genera and 4 families. The highest total species richness was recorded in Baltimore (16), while Budapest and the Finnish cities had relatively low (5–6) species numbers. Remnant forests and lawns supported the highest earthworm biomass. Soil properties (i.e. pH and organic matter content) explained neither earthworm community composition nor abundance. Evaluating all cities together, earthworm communities were significantly structured by habitat type. Communities in the two adjacent cities, Helsinki and Lahti were very similar, but Budapest clearly separated from the Finnish cities. Earthworm community structure in Baltimore overlapped with that of the other cities. Despite differences in climate, soils and biogeography among the cities, earthworm communities were highly similar within the urban habitat types. This indicates that human-mediated dispersal is an important factor shaping the urban fauna, both at local and regional scales.Peer reviewe

Adrenocorticotrophic hormone-stimulated cortisol release by the head kidney inter-renal tissue from sea bream (Sparus aurata) fed with linseed oil and soyabean oil

The mode of action of highly unsaturated fatty acids (HUFA) in regulating gilthead sea bream (Sparus aurata) head kidney (HK) cortisol production was studied through in vitro trials using a dynamic superfusion system. Fish were previously fed with different diets containing several inclusion levels of linseed oil (LO) or soyabean oil (SO) for 26 weeks. Five diets were tested; anchovy oil was the only lipid source for the control diet (fish oil, FO) and two different substitution levels (70 and 100 %) were tested using either LO or SO (70LO, 70SO, 100LO and 100SO). Fatty acid compositions of the HK reflected the dietary input, thus EPA, DHA, arachidonic acid and n-3 HUFA were significantly (P,0·05) reduced in fish fed vegetable oils compared with fish fed the FO diet. Feeding 70 or 100% LO increased significantly (P,0·05) cortisol release in HK after stimulation with adrenocorticotrophic hormone (ACTH), while feeding SO had no effect on this response. Cortisol stimulation factor (SF) was increased in fish fed the 70LO and 100LO diets compared with fish fed the control diet. Moreover, eicosanoid inhibition by incubating the HK tissue with indomethacin (INDO) as a cyclo-oxygenase (COX) inhibitor, or nordihydroguaiaretic acid (NDGA) as a lipoxygenase (LOX) inhibitor, significantly reduced (P,0·05) the cortisol release after ACTH stimulation in the 70LO and 100LO diets. Cortisol SF was reduced in the FO, 70LO and 100LO diets when incubating the HK with INDO or NDGA, while it was increased in the 70SO diet. The present results indicate that changing the fatty acid profile of gilthead sea bream HK by including LO and/or SO in the fish diet affected the in vitro cortisol release, and this effect is partly mediated by COX and/or LOX metabolites

The Belgic Confession

This book investigates the contemporary relevance of the Belgic Confession. The book groups the 37 articles of the Belgic Confession together in order to cover the whole confession in 12 chapters (alongside an introductory chapter). The emphasis of the publication falls on two aspects: (1) providing a scope of contemporary theological, ethical and general issues and possible controversies regarding the content of the Belgic Confession; and (2) formulating ethical perspectives and guidelines from the Belgic Confession that may assist in the building of societies. Where applicable, chapters also discuss the history of the text of the Belgic Confession, the organic unity between the articles of the Belgic Confession, a dogma-historical perspective on the development of the doctrine/content of the Belgic Confession and the relationship between the Belgic Confession and other confessions

Előzetes eredmények városi talajok lebontó hatásfokának vizsgálatáról (GLUSEEN-Projekt, Budapest)

A „Global Urban Soil Ecology and Education” hálózat előkészítő kutatása második éve folyik – a világ 4 régiójának 5 helyszínén –, Magyarország részvételével. A kutatás célja az ún. „konvergencia hipotézis” tesztelése különböző minőségű/zavartságú városi talajok szerves anyag lebontási hatásfokán keresztül. A konvergencia hipotézis szerint a természetes ökoszisztémák az urbanizáció hatására hasonló irányú változást mutatnak globális szinten. A cél mind tudományos igényű kutatások, mind az érdeklődő lakosság bevonására alkalmas egyszerű, könnyen kivitelezhető, költséghatékony módszerek kidolgozása, tesztelése. A kutatás során 4 élőhelytípust (5–5 ismétlésben) jelöltünk ki: 1) erősen zavart (ruderális), 2) városi gyep, 3) az urbanizáció eredményeként fragmentálódott erdőfoltok és 4) referenciaként szolgáló természetközeli erdők területei. A szervesanyag bomlásának mértékét 2013-ban leásott teafilterekkel vizsgáltuk, amelyeket 4, 6, 10, 12 hónap után gyűjtöttünk vissza. Eredményeink szerint a 6. hónaptól szignifikáns különbség mutatkozott az élőhelytípusok között a lebontási sebességben (F = 11,238; p < 0,0001), ami a városi gyepeken és ruderális élőhelyeken volt a legnagyobb. Ez összhangban van a többi 4 városban kapott eredménnyel, ami alátámasztja a konvergencia hipotézist: a különböző éghajlatú, alapkőzetű talajok kémhatása és humusztartalma az erősen zavart és városi gyep élőhelyek esetén azonos irányú változást mutatnak világszerte

RosettaScripts: A Scripting Language Interface to the Rosetta Macromolecular Modeling Suite

Macromolecular modeling and design are increasingly useful in basic research, biotechnology, and teaching. However, the absence of a user-friendly modeling framework that provides access to a wide range of modeling capabilities is hampering the wider adoption of computational methods by non-experts. RosettaScripts is an XML-like language for specifying modeling tasks in the Rosetta framework. RosettaScripts provides access to protocol-level functionalities, such as rigid-body docking and sequence redesign, and allows fast testing and deployment of complex protocols without need for modifying or recompiling the underlying C++ code. We illustrate these capabilities with RosettaScripts protocols for the stabilization of proteins, the generation of computationally constrained libraries for experimental selection of higher-affinity binding proteins, loop remodeling, small-molecule ligand docking, design of ligand-binding proteins, and specificity redesign in DNA-binding proteins