50 research outputs found

    Caracterización de las ganaderías de vacuno de carne en la zona de la Cooperativa Andaluza Ganadera del Valle de los Pedroches

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    publishedTomo I. Sección: Sistemas Ganaderos - Economía y Gestión. Sesión: Vacuno carne

    Bladder cancer index: cross-cultural adaptation into Spanish and psychometric evaluation

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    BACKGROUND: The Bladder Cancer Index (BCI) is so far the only instrument applicable across all bladder cancer patients, independent of tumor infiltration or treatment applied. We developed a Spanish version of the BCI, and assessed its acceptability and metric properties. METHODS: For the adaptation into Spanish we used the forward and back-translation method, expert panels, and cognitive debriefing patient interviews. For the assessment of metric properties we used data from 197 bladder cancer patients from a multi-center prospective study. The Spanish BCI and the SF-36 Health Survey were self-administered before and 12 months after treatment. Reliability was estimated by Cronbach's alpha. Construct validity was assessed through the multi-trait multi-method matrix. The magnitude of change was quantified by effect sizes to assess responsiveness. RESULTS: Reliability coefficients ranged 0.75-0.97. The validity analysis confirmed moderate associations between the BCI function and bother subscales for urinary (r = 0.61) and bowel (r = 0.53) domains; conceptual independence among all BCI domains (r ≤ 0.3); and low correlation coefficients with the SF-36 scores, ranging 0.14-0.48. Among patients reporting global improvement at follow-up, pre-post treatment changes were statistically significant for the urinary domain and urinary bother subscale, with effect sizes of 0.38 and 0.53. CONCLUSIONS: The Spanish BCI is well accepted, reliable, valid, responsive, and similar in performance compared to the original instrument. These findings support its use, both in Spanish and international studies, as a valuable and comprehensive tool for assessing quality of life across a wide range of bladder cancer patients

    Incidence, clinical characteristics and management of inflammatory bowel disease in Spain: large-scale epidemiological study

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    (1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD—Crohn’s disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)—during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100, 000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31–56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery. © 2021 by the authors. Licensee MDPI, Basel, Switzerland

    Nurses' perceptions of aids and obstacles to the provision of optimal end of life care in ICU

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    Contains fulltext : 172380.pdf (publisher's version ) (Open Access

    Optimisation of pressurised liquid extraction for the determination of monosaccharides and polyalcohols in woods used in wine aging

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    Background: The carbohydrate profile of woods used to age wines and spirits is largely unstudied in spite of its possible influence on the quality of aged beverages. This experiment evaluated the feasibility of employing pressurized liquid extraction to isolate monosaccharides and polyalcohols from woods used in aging, yielding a reliable analytical extraction method for characterising these compounds. Various solvents were tested and the extraction procedure was optimised by a three-level factorial experimentaldesign based on two main factors: extraction temperatureandextraction time. The totalextraction yield of target compounds was taken as response variable, and model parameters were estimated by multiple linear regression. Results: Methanol was best at extracting the target compounds and hence was selected as solvent. Temperature was the most important factor in the extraction process, and the optimal extraction conditions were 90°C for 15 min. Conclusion: Pressurised liquid extraction proved to be a highly suitable and powerful technique for extracting the monosaccharides and polyalcohols from wood samples. Analysis of the carbohydrate profile of the woods revealed differences among samples of different species and types of wood. © 2009 Society of Chemical Industry.Peer Reviewe

    Influence of geographical location, site and silvicultural parameters, on volatile composition of Quercus pyrenaica Willd. wood used in wine aging

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    For the current study, the volatile and semi-volatile composition of several samples of Quercus pyrenaica wood from NW Spain were analyzed and compared. The research was performed on a wide sample set of more than 100 samples (test tubes) obtained from different stands of this species. The relationship between some silvicultural and site parameters and volatile composition was studied. Altitude seemed to be the most influential parameter on the volatile composition. However, other factors such as distance from tree center, average annual precipitation, and number of trees per hectare whose effects on the volatile compounds were not significant. The influence of soil texture was not a determining factor while geographical location seemed to have a more specific impact on the extractive volatile content. The content of all extractable compounds studied allowed a good separation of oak samples of the same species according to their geographical origin. © 2011 Elsevier B.V.Peer Reviewe

    A STUDY OF THE ANTIOXIDANT CAPACITY OF OAK WOOD USED IN 1 WINE AGEING AND THE CORRELATION WITH POLYPHENOL 2 COMPOSITION 3 4

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    Abstract 26 27 The antioxidant capacity of oak wood used in the ageing of wine was studied by four 28 different methods: measurement of scavenging capacity against a given radical (ABTS, 29 DPPH), oxygen radical absorbance capacity (ORAC) and the ferric reducing antioxidant 30 power (FRAP). Although, the four methods tested gave comparable results for the 31 antioxidant capacity measured in oak wood extracts, the ORAC method gave results 32 with some differences from the other methods. Non-toasted oak wood samples 33 displayed more antioxidant power than toasted ones due to differences in the 34 polyphenol compositon. A correlation analysis revealed that ellagitannins were the 35 compounds mainly responsible for the antioxidant capacity of oak wood. Some phenolic 36 acids, mainly gallic acid, also showed a significant correlation with antioxidant 37 capacity. 38 3

    Antimicrobial and antioxidant activity of pressurized liquid extracts from oenological woods

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    The main goal of this study was to evaluate the antimicrobial activity of a collection of oenological woods extracts (non-toasted and toasted American oak wood, non-toasted and toasted French oak wood, non-toasted and toasted Rumanian oak wood, chestnut, cherry and wine grape wood) isolated by pressurized liquid extraction in order to control the microbial spoilage of wines. Inhibition of the growth of six wine lactic acid bacteria (LAB) (Lactobacillus hilgardii CIAL-49, Lactobacillus casei CIAL-52, Lactobacillus plantarum CIAL-92, Pedioccocus pentosaceus CIAL-85, Oenococcus oeni CIAL-91 and CIAL-96), two acetic acid bacteria (AAB) (Acetobacter aceti CIAL-106 and Gluconobacter oxydans CIAL-107) and three Brettanomyces yeast (Brettanomyces bruxellensis CIAL-108, CIAL-109 and CIAL-110) by the oenological wood extracts was assessed. The antioxidant activity and the total phenol index of wood extracts were also evaluated. Results confirmed differences in bacteria and yeast susceptibility to oenological wood extracts among different genera and species. Among them, AAB were especially sensitive to the phenolic inactivation from oenological woods extracts. Contrarily, amongst LAB, L.hilgardii CIAL-49 was the most resistant strain to the action of the wood extracts. Cherry wood was active against 9 of the 11 strains tested meanwhile French, Rumanian oak wood and chestnut show the lowest values of IC50 for A.aceti CIAL-106. No significant correlation was found between antimicrobial activity either with antioxidant activity or with the total phenol content, suggesting that structure-function of the phenolic extracts has a greater influence on the antimicrobial activity than the total phenol content.Authors are grateful to the Spanish Ministry of Economy and Competitiveness (MINECO) for its financial support towards the Projects AGL2012-04172-C02-01and PRI-PIBAR-2011-1358. M.E. Alañón would like to thank Fundación Alfonso Martín Escudero for the post-doctoral fellowship awarded.Peer Reviewe
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