Internet Advocacy Support for Families of Children with Emotional Difficulties

Archival data from a survey of parents of children with emotional difficulties who are members of a specific online support group are examined to determine to what degree, if any, those parents are using internet resources to access sources of information for advocacy. Twelve specific variables were collapsed into four sources of importance: Legal, School, Personal and Online sources that served as the dependent variables. Demographic data were collected and parent income was collapsed into three variables: Upper, Middle and Lower. Parent level of education was collapsed into three categories: College degree and above, Some college, and High school and below, and served as the independent variables. A One Group Repeated Measures Multiple Analysis of Variance (MANOVA) was utilized to examine the differences among the means of the parent reported scores of importance of the sources of information with results yielding significant differences for all four variables and a main effect for income by source. No interaction effects were found

B835: Landfills and Municpal Solid Waste in Maine

Municipal leaders need current information about alternative disposal methods to make rational decisions on handling their town\u27s waste. To provide an overview of landfilling and other waste-handling methods used in the upper New England states, a group of university researchers from New Hampshire, Maine, and Vermont initiated a study of landfills and solid waste management practices. The study involved a comprehensive mail survey of municipalities in Maine, New Hampshire, and Vermont. This report focuses upon and discusses the results of the landfill and solid waste management survey for Maine.https://digitalcommons.library.umaine.edu/aes_bulletin/1019/thumbnail.jp

Gender Differences and the Influence of Body Composition on Land and Pool-Based Assessments of Anaerobic Power and Capacity

Consistent differences between males and females have been shown in land-based measurements of anaerobic power and capacity. However, these differences have not been investigated for a tethered 30-s maximal swimming test (TST). The purpose of this study is to explore gender differences in land and pool-based assessments of anaerobic power (F(peak)) and capacity (F(mean)), as well as the influence of body composition. Thirteen males and fifteen females completed land (Wingate (WAnT)) and pool-based (TST) measures of anaerobic power and capacity previously described in the literature. Additionally, the subjects completed assessments of body composition via air displacement plethysmography. The males produced higher force than the females for F(peak) (p < 0.001) and F(mean) (p = 0.008) during the TST. However, linear regression analysis determined that lean mass significantly predicted F(peak) (p = 0.002) and F(mean) (p < 0.001) during the TST, while gender was no longer significant (p = 0.694 and p = 0.136, respectively). In conclusion, increases in anaerobic power and capacity (F(peak) and F(mean)) may be a function of increased lean mass in males and females, warranting future research on the impact of resistance training programs on force production and swimming performance

Human Bacterial Artificial Chromosome (BAC) Transgenesis Fully Rescues Noradrenergic Function in Dopamine β-Hydroxylase Knockout Mice

Dopamine β-hydroxylase (DBH) converts dopamine (DA) to norepinephrine (NE) in noradrenergic/adrenergic cells. DBH deficiency prevents NE production and causes sympathetic failure, hypotension and ptosis in humans and mice; DBH knockout (Dbh -/-) mice reveal other NE deficiency phenotypes including embryonic lethality, delayed growth, and behavioral defects. Furthermore, a single nucleotide polymorphism (SNP) in the human DBH gene promoter (-970C\u3eT; rs1611115) is associated with variation in serum DBH activity and with several neurological- and neuropsychiatric-related disorders, although its impact on DBH expression is controversial. Phenotypes associated with DBH deficiency are typically treated with L-3,4-dihydroxyphenylserine (DOPS), which can be converted to NE by aromatic acid decarboxylase (AADC) in the absence of DBH. In this study, we generated transgenic mice carrying a human bacterial artificial chromosome (BAC) encompassing the DBH coding locus as well as ~45 kb of upstream and ~107 kb of downstream sequence to address two issues. First, we characterized the neuroanatomical, neurochemical, physiological, and behavioral transgenic rescue of DBH deficiency by crossing the BAC onto a Dbh -/- background. Second, we compared human DBH mRNA abundance between transgenic lines carrying either a C or a T at position -970. The BAC transgene drove human DBH mRNA expression in a pattern indistinguishable from the endogenous gene, restored normal catecholamine levels to the peripheral organs and brain of Dbh -/- mice, and fully rescued embryonic lethality, delayed growth, ptosis, reduced exploratory activity, and seizure susceptibility. In some cases, transgenic rescue was superior to DOPS. However, allelic variation at the rs1611115 SNP had no impact on mRNA levels in any tissue. These results indicate that the human BAC contains all of the genetic information required for tissue-specific, functional expression of DBH and can rescue all measured Dbh deficiency phenotypes, but did not reveal an impact of the rs11115 variant on DBH expression in mice

Three Novel Pigmentation Mutants Generated by Genome-Wide Random ENU Mutagenesis in the Mouse

Three mutant mice with pigmentation phenotypes were recovered from a genomewide random mouse chemical mutagenesis study. White toes (Whto; MGI:1861986), Belly spot and white toes (Bswt; MGI:2152776) and Dark footpads 2 (Dfp2; MGI:1861991) were identified following visual inspection of progeny from a male exposed to the point mutagen ethylnitrosourea (ENU). In order to rapidly localize the causative mutations, genome-wide linkage scans were performed on pooled DNA samples from backcross animals for each mutant line. Whto was mapped to proximal mouse chromosome (Mmu) 7 between Cen (the centromere) and D7Mit112 (8.0 cM from the centromere), Bswt was mapped to centric Mmul between D1Mit214 (32.1 cM) and D1Mit480 (32.8 cM) and Dfp2 was mapped to proximalMmu4 between Cen and D4Mit18 (5.2 cM). Whto, Bswt and Dfp2 may provide novel starting points in furthering the elucidation of genetic and biochemical pathways relevant to pigmentation and associated biological processes

A Cultural Species and its Cognitive Phenotypes: Implications for Philosophy

After introducing the new field of cultural evolution, we review a growing body of empirical evidence suggesting that culture shapes what people attend to, perceive and remember as well as how they think, feel and reason. Focusing on perception, spatial navigation, mentalizing, thinking styles, reasoning (epistemic norms) and language, we discuss not only important variation in these domains, but emphasize that most researchers (including philosophers) and research participants are psychologically peculiar within a global and historical context. This rising tide of evidence recommends caution in relying on one’s intuitions or even in generalizing from reliable psychological findings to the species, Homo sapiens. Our evolutionary approach suggests that humans have evolved a suite of reliably developing cognitive abilities that adapt our minds, information-processing abilities and emotions ontogenetically to the diverse culturally-constructed worlds we confront

Public Response to Community Mitigation Measures for Pandemic Influenza

Results from a national survey indicated that most persons would follow public health officials’ guidelines

Spoken word recognition of novel words, either produced or only heard during learning

This document is the Accepted Manuscript Version of the following article: Tania S. Zamuner, Elizabeth Morin-Lessard, Stephanie Strahm, and Michael P. A. Page, 'Soke word recognition of novel words, either produced or only heard during learning', Journal of Memory and Language, Vol. 89, August 2016, pp. 55-67, doi: 10.1016/j.jml.2015.10.003. Under embargo. Embargo end date: 1 December 2017. This manuscript version is made available under the CC-BY-NC-ND 4.0 license http://creativecommons.org/licenses/by-nc-nd/4.0/Psycholinguistic models of spoken word production differ in how they conceptualize the relationship between lexical, phonological and output representations, making different predictions for the role of production in language acquisition and language processing. This work examines the impact of production on spoken word recognition of newly learned non-words. In Experiment 1, adults were trained on non-words with visual referents; during training, they produced half of the non-words, with the other half being heard-only. Using a visual world paradigm at test, eye tracking results indicated faster recognition of non-words that were produced compared with heard-only during training. In Experiment 2, non-words were correctly pronounced or mispronounced at test. Participants showed a different pattern of recognition for mispronunciation on non-words that were produced compared with heard-only during training. Together these results indicate that production affects the representations of newly learned words.Peer reviewedFinal Accepted Versio

Comparative Analysis of Illicit Supply Network Structure and Operations: Cocaine, Wildlife, and Sand

Illicit supply networks (ISNs) are composed of coordinated human actors that source, transit, and distribute illicitly traded goods to consumers, while also creating widespread social and environmental harms. Despite growing documentation of ISNs and their impacts, efforts to understand and disrupt ISNs remain insufficient due to the persistent lack of knowledge con-necting a given ISN’s modus operandi and its patterns of activity in space and time. The core challenge is that the data and knowledge needed to integrate it remain fragmented and/or compartmentalized across disciplines, research groups, and agencies tasked with understanding or monitoring one or a few specific ISNs. One path forward is to conduct comparative analyses of multiple diverse ISNs. We present and apply a conceptual framework for linking ISN modus operandi to spatial-temporal dynamics and patterns of activity. We demonstrate this through a comparative analysis of three ISNs – cocaine, illegally traded wildlife, and illegally mined sand – which range from well-established to emergent, global to domestic in geographic scope, and fully illicit to de facto legal. The proposed framework revealed consistent traits related to geographic price structure, value capture at different supply chain stages, and key differ-ences among ISN structure and operation related to commodity characteristics and their relative illicitness. Despite the diversity of commodities and ISN attributes compared, social and environmental harms inflicted by the illicit activity consistently become more widespread with increasing law enforcement disruption. Drawing on these lessons from diverse ISNs, which varied in their histories and current sophistication, possible changes in the structure and function of nascent and/or low salience ISNs may be anticipated if future conditions or law enforcement pressure change