Manejo exitoso de perforación gástrica secundaria a plicatura de curvatura mayor laparoscópica con gastrostomía endoscópica percutánea con avance yeyunal y sellador de fibrina

ResumenUna de las complicaciones más frecuentes de los procedimientos bariátricos es la fuga gástrica, ya sea debido a dehiscencia de línea de grapado o por perforación gástrica. Estas varían dependiendo del tipo de cirugía, reportándose del 2.05-5.2% en bypass gástrico en Y de Roux, el 5.1% en manga gástrica y el 1.4% en plicatura gástrica. Actualmente, se recomienda manejo de mínima invasión con lo cual se disminuye morbilidad. Presentamos un caso clínico de perforación secundario a plicatura gástrica con exitoso manejo endoscópico.AbstractGastric leak, caused by staple line disruption or gastric perforation, is one of the most dreaded complications following bariatric surgery. The reported incidence of leakage varies depending on type of surgery, from 2.05% to 5.20% for Roux-en-Y gastric bypass, 5.1% in sleeve gastrectomy, and 1.4% in gastric plication. Minimally invasive management is currently recommended to minimise morbidity. The case is presented of a patient who suffered a gastric perforation following a laparoscopic greater curvature plication, with successful endoscopic management

Tool support for Generating User Acceptance Tests

Software testing, in particular acceptance testing, is a very important step in the development process of any application since it represents a way of matching the users’ expectations with the finished product´s capabilities. Typically considered as a cumbersome activity, many efforts have been made to alleviate the burden of writing tests by, for instance, trying to generate them automatically. However, testing still remains a largely neglected step. In this paper we propose taking advantage of existing requirement artifacts to semi-automatically generate acceptance tests. This paper extends a previous paper in which we use Scenarios, a requirement artifact used to describe business processes and requirements, and Task/Method models, a modelling approach taken from the Artificial Intelligence field. The proposed approach derives a Task/Method model from Scenario (through rules) and from the Task/Method model specification, all alternatives in the flow of execution are provided. Using the proposed ideas, we show how the semi-automated generation of acceptance tests can be implemented by describing an ongoing development of a proof of concept web application designed to support the full process.Laboratorio de Investigación y Formación en Informática Avanzad

Informe de autoevaluación de la Facultad de Psicología de la Universidad Nacional Mayor de San Marcos (desde la perspectiva de los estudiantes)

Tiene como objetivo evaluar, desde la perspectiva de los estudiantes, el funcionamiento de la Facultad de Psicología de la Universidad Nacional Mayor de San Marcos (UNMSM), específicamente en lo que concierne a la carrera de psicología, teniendo como referencia los criterios planteados por el Sistema Nacional de Evaluación, Acreditación y Certificación de la Calidad Educativa (SINEACE). Para lograr dicho objetivo se realizó un estudio empírico–descriptivo, por medio de un cuestionario ad hoc basado en los criterios propuestos por el SINEACE, el cual se aplicó a 296 estudiantes de la Escuela Profesional de Psicología General de la Facultad de Psicología de la UNMSM, que equivalen al 45% de la población total. Los resultados mostraron que un número elevado de estudiantes no contaron con información suficiente y manejaron información errónea acerca del actual funcionamiento de la facultad de psicología. A través del proceso de verificación de fuentes de información se concluyó que la carrera cumple con 3 de 7 estándares propuestos en la dimensión “Gestión estratégica”, 11 de 18 en la dimensión “Formación Integral”, ninguno de 6 estándares en la dimensión “Soporte Institucional” y ninguno de los 2 en la dimensión “Resultados”. Además, los estudiantes presentaron porcentajes muy elevados de respuestas incompatibles con las fuentes de verificación. En síntesis, se concluye que los estudiantes, probablemente por los elevados porcentajes de desinformación o manejo de información errada, consideran que la carrera de Psicología presenta un funcionamiento parcialmente apropiado con respecto a los requisitos establecidos por el SINEACE

Correction : Chaparro et al. Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain: Large-Scale Epidemiological Study. J. Clin. Med. 2021, 10, 2885

The authors wish to make the following corrections to this paper [...]

Incidence, Clinical Characteristics and Management of Inflammatory Bowel Disease in Spain : Large-Scale Epidemiological Study

(1) Aims: To assess the incidence of inflammatory bowel disease (IBD) in Spain, to describe the main epidemiological and clinical characteristics at diagnosis and the evolution of the disease, and to explore the use of drug treatments. (2) Methods: Prospective, population-based nationwide registry. Adult patients diagnosed with IBD-Crohn's disease (CD), ulcerative colitis (UC) or IBD unclassified (IBD-U)-during 2017 in Spain were included and were followed-up for 1 year. (3) Results: We identified 3611 incident cases of IBD diagnosed during 2017 in 108 hospitals covering over 22 million inhabitants. The overall incidence (cases/100,000 person-years) was 16 for IBD, 7.5 for CD, 8 for UC, and 0.5 for IBD-U; 53% of patients were male and median age was 43 years (interquartile range = 31-56 years). During a median 12-month follow-up, 34% of patients were treated with systemic steroids, 25% with immunomodulators, 15% with biologics and 5.6% underwent surgery. The percentage of patients under these treatments was significantly higher in CD than UC and IBD-U. Use of systemic steroids and biologics was significantly higher in hospitals with high resources. In total, 28% of patients were hospitalized (35% CD and 22% UC patients, p < 0.01). (4) Conclusion: The incidence of IBD in Spain is rather high and similar to that reported in Northern Europe. IBD patients require substantial therapeutic resources, which are greater in CD and in hospitals with high resources, and much higher than previously reported. One third of patients are hospitalized in the first year after diagnosis and a relevant proportion undergo surgery

Clonal chromosomal mosaicism and loss of chromosome Y in elderly men increase vulnerability for SARS-CoV-2

The pandemic caused by severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2, COVID-19) had an estimated overall case fatality ratio of 1.38% (pre-vaccination), being 53% higher in males and increasing exponentially with age. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, we found 133 cases (1.42%) with detectable clonal mosaicism for chromosome alterations (mCA) and 226 males (5.08%) with acquired loss of chromosome Y (LOY). Individuals with clonal mosaic events (mCA and/or LOY) showed a 54% increase in the risk of COVID-19 lethality. LOY is associated with transcriptomic biomarkers of immune dysfunction, pro-coagulation activity and cardiovascular risk. Interferon-induced genes involved in the initial immune response to SARS-CoV-2 are also down-regulated in LOY. Thus, mCA and LOY underlie at least part of the sex-biased severity and mortality of COVID-19 in aging patients. Given its potential therapeutic and prognostic relevance, evaluation of clonal mosaicism should be implemented as biomarker of COVID-19 severity in elderly people. Among 9578 individuals diagnosed with COVID-19 in the SCOURGE study, individuals with clonal mosaic events (clonal mosaicism for chromosome alterations and/or loss of chromosome Y) showed an increased risk of COVID-19 lethality

COMPARISON BETWEEN VISUAL ASSESSMENT AND MEASUREMENT OF HEART GIRTH OR HIP-WIDTH TO ESTIMATE LIVE WEIGHT IN CROSSBRED BEEF HEIFERS

Background. Estimation of animal body weight (BW) is a fundamental tool in herd management for the development of reproductive, nutritional and health programmes. Objective. To compare the actual BW and its estimation by visual method and measurement of the heart girth (HG) or hip width (HW) for estimating BW in crossbred beef heifers reared under humid tropical conditions in Mexico. Methodology. Data on GH, HW, BW estimated by the visual method (MV) and actual BW were recorded in 105 crossbred replacement heifers (Bos taurus × Bos indicus) Swiss American, Beef Master, Simmental, and Brahman with different degrees of crossbreeding. Heifers ranged in age from three to 20 months and were grazed on star grass (Cynodon nlemfuensis) and humidicola grass (Brachiaria humidicola) pastures without supplementation. BW was recorded using a digital scale, HG was measured using a flexible fibreglass tape and HW was measured using a 65 cm forceps. BW by visual estimation was considered as the average of three observations made by three observers, HG and HW methods using the formula 1) BW (kg): 202.68 - 4.39 × HG + 0.03 × HG2; 2) BW (kg): 0.26 × HW1.90. The Pearson coefficient and the distribution (density) of each variable, were assessed using a correlation matrix graph. Also, a comparison the measures obtained by each of the different estimation methods with the observed weights, by inspecting the paired Bland-Altman plots, prior to logarithmic transformation. Results. Correlations between observed BW and predicted BW for the HG, HW and visual methods showed a positive and significant relationship (P<0.001), with r values of 0.95, 0.89 and 0.92, respectively. The HG method tended to overestimate the real BW, whereas, in the visual and HW methods, the values are evenly and randomly distributed around the line, indicating that these methods neither underestimated nor overestimated the BW. Implications. Although the HG method showed the highest correlation coefficient between observed and predicted BW, the result of the present study showed that visual assessment highlights the ability of observers to visually estimate the BW of growing heifers. Conclusion. Livestock handlers have a very accurate estimation of BW. The use of alternative methods to scales, such as the HG measuring method, can be useful and practical tools to improve the accuracy of the assessment

Current and future trends in multimodality imaging of coronary artery disease

Nowadays, there is a wide array of imaging studies available for the evaluation of coronary artery disease, each with its particular indications and strengths. Cardiac single photon emission tomography is mostly used to evaluate myocardial perfusion, having experienced recent marked improvements in image acquisition. Cardiac PET has its main utility in perfusion imaging, atherosclerosis and endothelial function evaluation, and viability assessment. Cardiovascular computed tomography has long been used as a reference test for non-invasive evaluation of coronary lesions and anatomic characterization. Cardiovascular magnetic resonance is currently the reference standard for non-invasive ventricular function evaluation and myocardial scarring delineation. These specific strengths have been enhanced with the advent of hybrid equipment, offering a true integration of different imaging modalities into a single, simultaneous and comprehensive study