Diagnostic concordance of DSM-IV and DSM-5 Posttraumatic Stress Disorder (PTSD) in a clinical sample

The present study aims to analyze diagnostic concordance between the DSM-IV and the DSM-5 for posttraumatic stress disorder (PTSD) diagnostic criteria and their different groups of symptoms. Furthermore, analyses are conducted to establish the features of participants with no concordant diagnoses. Method: The study assessed 166 people over 18 who had experienced at least one traumatic event. PTSD diagnosis was established using the Global Scale for Posttraumatic Stress (EGEP), a self-report measure to assess PTSD. Results: The presence of cognitive avoidance was a determinant in the PTSD DSM-5 diagnosis (86% positive predictive value). The analysis of the non-concordant individuals revealed that individuals who were diagnosed according to the DSM-IV criteria but not the DSM-5 criteria were primarily indirect victims. Conversely, individuals who were diagnosed with the DSM-5 criteria and not with the DSM-IV criteria presented cognitive avoidance and alterations in cognition not included in the DSM-IV criteria. Conclusions: A withinsubjects concordance analysis showed high agreement for PTSD diagnosis between the two classifi cations. Differences between the diagnoses are due to the new defi nition of C (avoidance) and D (negative alterations in cognitions and mood) in the DSM-

Classes of sum-of-cisoids processes and their statistics for the modeling and simulation of mobile fading channels

In this paper, we present a fundamental study on the stationarity and ergodicity of eight classes of sum-of-cisoids (SOC) processes for the modeling and simulation of frequency-nonselective mobile Rayleigh fading channels. The purpose of this study is to determine which classes of SOC models enable the design of channel simulators that accurately reproduce the channel’s statistical properties without demanding information on the time origin or the time-consuming computation of an ensemble average. We investigate the wide-sense stationarity, first-order stationarity of the envelope, mean ergodicity, and autocorrelation ergodicity of the underlying random processes characterizing the different classes of stochastic SOC simulators. The obtained results demonstrate that only the class of SOC models comprising cisoids with constant gains, constant frequencies, and random phases is defined by a set of stationary and ergodic random processes. The analysis presented here can easily be extended with respect to the modeling and simulation of frequency-selective single-input single-output (SISO) and multiple-input multiple-output channels. For the case of frequency-selective SISO channels, we investigate the stationarity and ergodicity in both time and frequency of 16 different classes of SOC simulation models. The findings presented in this paper can be used in the laboratory as guidelines to design efficient simulation platforms for the performance evaluation of modern mobile communication systems

La información científica en la televisión

En esta comunicación se presentan unos materiales en los que se aprovecha el potencial de las noticias científicas emitidas por televisión para elaborar unidades didácticas que se pueden utilizar en las clases de Ciencias de la Naturaleza de los últimos cursos de ESO o en la materia CMC de Bachillerato. Los alumnos aprenden a analizar la información presente en esas noticias señalando sus aspectos positivos y negativos, profundizando en el conocimiento de los conceptos implicados

La información científica en la televisión

En esta comunicación se presentan unos materiales en los que se aprovecha el potencial de las noticias científicas emitidas por televisión para elaborar unidades didácticas que se pueden utilizar en las clases de Ciencias de la Naturaleza de los últimos cursos de ESO o en la materia CMC de Bachillerato. Los alumnos aprenden a analizar la información presente en esas noticias señalando sus aspectos positivos y negativos, profundizando en el conocimiento de los conceptos implicados

Adapting an Awareness Tool for Massive Courses: the Case of ClassON

Abstract: In this paper we analyse the challenges posed to teachers and students in massive face-to-face classes and explore how existing solutions can be applied to these contexts. In particular, we focus on classON 1 , a tool that provides teachers and students with the appropriate information to make the most out of face-to-face sessions in the computer lab. classON has been well tested in small-medium face-to-face lab sessions and we discuss some of its characteristics (current ones and foreseen) to adapt it to massive courses. As a result, we provide a set of recommendations for adapting tools to support massive face-to-face learning activities

Teleorientación y teleseguimiento en la ingesta alimentaria de pacientes con hipertensión arterial y diabetes mellitus

Objective: To describe the food intake of patients with hypertension and diabetes mellitus before and after teleorientation and telemonitoring sessions. Materials and methods: A quasi-experimental study conducted with 80 participants with a diagnosis of hypertension and diabetes mellitus, whose food intake was evaluated at the beginning of the intervention and at the end of the scheduled teleorientation and telemonitoring sessions. Results: At the beginning of the intervention, only 6.25 % of the participants showed an adequate food intake, which increased to 71.25 % at the end of the scheduled teleorientation and telemonitoring sessions. Conclusions: The implementation of a nutrition teleorientation and telemonitoring system in patients with hypertension and diabetes mellitus improves their food intake, thus confirming the efficacy of using ICTs in health interventions for the benefit of the population.Objetivo: Describir la ingesta alimentaria antes y después de las sesiones de teleorientación y teleseguimiento en pacientes con hipertensión arterial y diabetes mellitus. Materiales y métodos: Estudio de diseño cuasiexperimental en el cual se evaluó la ingesta alimentaria de 80 participantes, con diagnóstico de hipertensión arterial y diabetes mellitus, al inicio de la intervención y al finalizar las sesiones de teleorientación y teleseguimiento programadas. Resultados: Al empezar la intervención solo el 6,25 % obtuvo una valoración de ingesta alimentaria adecuada, la cual aumentó hasta 71,25 % al finalizar las sesiones de teleorientación y teleseguimiento programadas. Conclusiones: La implementación de un sistema de teleorientación y teleseguimiento nutricional en pacientes con hipertensión arterial y diabetes mellitus mejora la ingesta alimentaria, lo que permite confirmar la eficacia del uso de las TIC en las intervenciones sanitarias para el beneficio de la población

Immune Checkpoint Inhibitors: The Emerging Cornerstone in Cholangiocarcinoma Therapy?

Background: Cholangiocarcinoma (CCA) encompasses a heterogeneous group of malignant tumors with dismal prognosis and increasing incidence worldwide. Both late diagnosis due to the lack of early symptoms and the refractory nature of these tumors seriously compromise patients' welfare and outcomes. Summary: During the last decade, immunotherapy and, more specifically, modulation of immune checkpoints-mediated signaling pathways have been under the spotlight in the field of oncology, emerging as a potential therapeutic approach for the treatment of several cancers, including CCA. Generally, high expression levels of immune checkpoints in patients with CCA have been associated with worse clinical outcomes, particularly with shorter overall survival and relapse-free survival. Thus, immune checkpoint inhibitors (ICIs), which mainly constitute different monoclonal antibodies, have been developed in order to hamper the immune checkpoint-mediated pathways. Interestingly, chemotherapy may increase the expression of immune checkpoints, while other therapeutic approaches such as ablative and targeted therapies may enhance their antitumor activity. In this sense, several clinical trials evaluated the safety and efficacy of ICIs for CCA, both as a monotherapy and in combination with other ICIs or loco-regional and systemic therapies. Additionally, many other clinical trials are currently ongoing and results are eagerly awaited. Here, we summarize the key aspects of immune checkpoint molecules as prognostic factors and therapeutic targets in CCA, highlighting the most recent advances in the field and future research directions. Key messages: (1) Effective therapeutic approaches for CCA are urgently needed. (2) Expression levels of immune checkpoints in patients with CCA have been proposed to be related with clinical outcomes. (3) Combination of different ICIs may outperform the efficacy of ICI monotherapy for CCA treatment. (4) Recent studies point toward the combination of ICIs and other common therapies, especially chemotherapy, as a promising strategy for treatment of CCA patients

Implementation and Effects of the Broad‑Minded Affective Coping (BMAC) Technique: a Pilot Study

This study aims to develop and test a 3-session version of the Broad-Minded Affective Coping (BMAC) technique and to explore the relationship between implementation (features of the positive memory evoked, satisfaction, and engagement) and outcome. The BMAC was delivered to 31 female university students in three sessions over 7–10 days. Positive and negative affect, and difficulties in regulation of negative and positive emotions were assessed pre-treatment and post-treatment. The intervention resulted in a significant reduction in negative affect and in difficulties in negative emotion regulation. No significant effects were found on positive affect or on difficulties in positive emotion regulation. Moreover, the memories chosen were found to be highly central, and patient and therapist levels of satisfaction and engagement in the technique were very high throughout the three sessions. No significant relationships were found between implementation and outcome. This leads to the conclusion that the technique may be suitable for inclusion in broader treatment packages

Experiencias y percepciones de los donantes de sangre sobre la donación en un hospital público de Perú

Objetivo: Conocer las experiencias y percepciones de donantes de sangre en un hospital público. Materiales y métodos: Se realizó un estudio cualitativo con orientación fenomenológica en un hospital público de Lima. Se realizaron entrevistas semiestructuradas a profundidad y notas de campo basadas en observaciones a los participantes. Resultados: Se entrevistó a doce donantes, los cuales manifestaron no haber tenido mucha información sobre la donación y el banco de sangre. Sin embargo, luego de su experiencia de donar se identificó aspectos positivos como la atención de calidad, rápida y minuciosa. Los participantes valoran el trato cordial del personal a la hora de brindar información, el reducido tiempo de espera y la compañía durante el proceso de extracción de la sangre. Los aspectos negativos fueron la falta de publicidad y difusión de la donación voluntaria de sangre. A pesar de ello la mayoría de entrevistados manifestaron su intención de retornar debido a la calidad del servicio. En resumen, la percepción de los participantes fue favorable a la donación, al recibir una atención de calidad, con información oportuna en el tiempo adecuado. Conclusiones: Los entrevistados no tenían mayor información sobre la posibilidad de hacer donaciones voluntarias de sangre en el hospital. Posterior a su experiencia, la percepción sobre la donación fue favorable, indicando su intención de participar en futuras donaciones