1,750 research outputs found
Training Maneuver Evaluation for Reduced Order Modeling of Stability & Control Properties Using Computational Fluid Dynamics
System identification has long been used as a tool for flight test engineers to characterize systems under test; however, the inputs to these characterization activities have previously been limited to wind tunnel and flight test data. There has been a recent effort to incorporate computational fluid dynamics (CFD) into the system identification process. An integral piece of the process is the simulation of training maneuvers utilizing CFD. Up until now, the suitability of particular training maneuvers has been assessed by comparing the reduced model to known results. This research strives to recommend a set of parameters to be used in determining a priori whether a training maneuver will be suitable under a particular set of flow conditions
Political Settlement in Solomon Islands: A Political Economic Basis for Stability after RAMSI? Political Settlement: Part 3
Political settlements and pacts now feature prominently in donor narratives about transitions from conflict and institutional fragility to peace and prosperity (Hickey 2013). Ten years after the Regional Assistance Mission to Solomon Islands (RAMSI) intervention, political settlement analysis offers fresh perspective on core questions: Are governing arrangements in Solomon Islands stable and sustainable? Where might they be ineffective and vulnerable?AusAI
Political settlement in Solomon Islands: a political economic basis for stability after RAMSI?
In this Working Paper, the authors discuss the prospects for stability in the post-RAMSI era in Solomon Islands, from a political economy perspective. This Working Paper was first delivered as a presentation at the Solomon Islands in Transition workshop, held at ANU on 4 - 5 November, 2013.AusAI
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The Interacting Effects of Anxiety Levels, Task Complexity, and Warm-Up Conditions on Learning a Serial Type Motor Task
The major purpose of this study was to determine the effects of manifest anxiety, task complexity, and warm-up conditions on learning a two-phase serial type motor task. Another purpose was to consider the implications of these effects for physical educators, coaches, and others interested in improving educational practices and securing optimum performance levels
Happiness, environmental protection and market economy
The manufacturing sector is leaving the West for Asiaâs low wages and good working culture. Europe would be better off keeping these manufacturing activities, slowing down wage inflation and what is more, letting a young, cheaper workforce from the East settle down within their borders. This would aid in preserving the diverse economic structure which has been characteristic for Europe.Beside the economic growth there are two more concepts which have turned into the âholy cowsâ of economics during the last fifty years. One is the need to constantly improve labor productivity and the other is increasing competitiveness of nations. The high labor productivity of some countries, induces severe unemployment in the globalized world. In the other hand it is high time we understood that it is not competition, but cooperation that brings more happiness to humanity.Should we still opt for âhappinessâ and âsanityâ, it is quite obvious that we all should, in economistsâ terms, define our individual welfare functions corresponding to our own set of values, staying free from the influence of media, advertisements and fashion. The cornerstone to all this is the intelligent citizen who prefers local goods and services
The Cyclin-dependent Kinase Activator, Spy1A, Is Targeted for Degradation by the Ubiquitin Ligase NEDD4
Spy1A is a cyclin-like protein required for progression through the G(1)/S phase of the cell cycle. Elevated Spy1A protein levels have been implicated in tumorigenesis and are attributed to overriding the DNA damage response and enhancing cell proliferation. Understanding how Spy1A is produced and degraded is essential in resolving how it contributes to normal and abnormal growth processes. Herein, we demonstrate that Spy1A is degraded in a cell cycle-dependent manner during mitosis via the ubiquitin-proteasome system. We have resolved the E3 ligase and essential phosphorylation sites mediating Spy1A degradation. Furthermore, we have determined that non-degradable forms of Spy1A do not trigger cell cycle arrest but, rather, contribute to uncontrolled cell growth. Further investigation into the regulation of Spy1A may reveal novel strategies for understanding the etiology and progression of specific growth disorders
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