591 research outputs found
Risk factors for overweight and overfatness in rural South African children and adolescents
Background To determine risk factors for overweight/overfatness in children and adolescents from rural KwaZulu-Natal, South Africa. Methods Anthropometric data were collected from a cross-sectional sample (n = 1519, ages 7, 11 and 15 years) and linked to demographic information (n = 1310 and n = 1317 in overweight and overfat analyses, respectively). Candidate risk factors for overweight/overfatness were identified and tested for associations with overweight (BMI-for-age >+1SD, WHO reference) and overfatness (>85th centile body fatness, McCarthy reference) as outcomes. Associations were examined using simple tests of proportions (χ2/Mann–Whitney U tests) and multivariable logistic regression. Results Sex was a consistent variable across both analyses; girls at significantly increased risk of overweight and overfatness (overweight: n = 180, 73.9 and 26.1% females and males, respectively (P < 0.0001); overfat: n = 187, 72.7 and 27.3% females and males, respectively (P < 0.0001)). In regression analyses, sex and age (defined by school grade) were consistent variables, with boys at lower risk of overweight (adjusted odds ratio (AOR) 0.40 (confidence interval (CI) -0.28–0.57)) and risk of overweight increasing with age (AOR 0.65 (CI- 0.44–0.96), 0.50 (CI-0.33–0.75) and 1.00 for school grades 1, 5 and 9, respectively). Results were similar for overfatness. Conclusions This study suggests that pre-adolescent/adolescent females may be the most appropriate targets of future interventions aimed at preventing obesity in rural South Africa
Keep it simple: ranking health states yields values similar to cardinal measurement approaches
Abstract
OBJECTIVES: To examine the relationship between ordinal and cardinal valuation of health states.
STUDY DESIGN AND SETTING: We analyzed rank, visual analog scale (VAS), and time trade-off (TTO) responses for 52 health states defined using the EQ-5D classification system developed by the EuroQol Group. We analyzed 179,431 responses from 11,483 subjects in eight countries: Slovenia, Argentina, Denmark, Japan, Netherlands, Spain, United Kingdom, and United States. We first compared responses across methods by frequency of ties and values below dead. Ordinal associations between methods were evaluated using Spearman's correlation and Kendall's tau. Next, we estimated numerical values from rank responses using country-specific conditional logit models. After anchoring predicted values on a common scale, we further investigated the cardinal relationships between rank, VAS, and TTO-based values using Pearson's rho and quadratic regression.
RESULTS: For each country, rank responses are less likely than TTO responses to be tied and to indicate that states are worse than dead. In all countries, rank responses show a strong linear correlation with both TTO (Pearson's rho=0.88-0.99) and VAS (rho=0.91-0.98) responses. However, rank-ba
Evaluation of sugarcane-derived polyphenols on the pre-weaning and post-weaning growth of gilt progeny
Gilt progeny (GP) exhibit poorer growth compared with sow progeny (SP), particularly in the pre-weaning and post-weaning period. Late gestation/lactation sow diets and weaner diets were supplemented with 0.5% Polygain (POL), a sugarcane extract rich in polyphenols, to collectively improve GP growth in these periods. Gilts (n = 60) and sows (n = 68, parities 2 and 3) were fed a control or POL diet. Weaned GP (n = 79) and SP (n = 92) born to these dams were also fed either a CON or POL diet. Gilts litters weighed less than sow litters at birth and 21 days (p < 0.001 for both) and were not improved by POL (p = 0.80 and 0.54, respectively). GP were lighter than SP at day 7 and day 14 post-weaning (p < 0.001 for both) and were not improved by the POL diet at these timepoints (p = 0.61 and 0.97, respectively). Plasma interleukin-1β (IL-1β) was increased at weaning despite POL supplementation (p = 0.022) and GP had reduced IL-1β overall (p = 0.021). Overall, POL was unable to improve growth in GP and the attenuated immune response seen in GP could be contributing to their poor growth performance
Consistent Histories in Quantum Cosmology
We illustrate the crucial role played by decoherence (consistency of quantum
histories) in extracting consistent quantum probabilities for alternative
histories in quantum cosmology. Specifically, within a Wheeler-DeWitt
quantization of a flat Friedmann-Robertson-Walker cosmological model sourced
with a free massless scalar field, we calculate the probability that the
univese is singular in the sense that it assumes zero volume. Classical
solutions of this model are a disjoint set of expanding and contracting
singular branches. A naive assessment of the behavior of quantum states which
are superpositions of expanding and contracting universes may suggest that a
"quantum bounce" is possible i.e. that the wave function of the universe may
remain peaked on a non-singular classical solution throughout its history.
However, a more careful consistent histories analysis shows that for arbitrary
states in the physical Hilbert space the probability of this Wheeler-DeWitt
quantum universe encountering the big bang/crunch singularity is equal to
unity. A quantum Wheeler-DeWitt universe is inevitably singular, and a "quantum
bounce" is thus not possible in these models.Comment: To appear in Foundations of Physics special issue on quantum
foundation
Elite male Flat jockeys display lower bone density and lower resting metabolic rate than their female counterparts: implications for athlete welfare
To test the hypothesis that daily weight-making is more problematic to health in male compared with female jockeys, we compared the bone-density and resting metabolic rate (RMR) in weight-matched male and female Flat-jockeys. RMR (kcal.kg-1 lean mass) was lower in males compared with females as well as lower bone-density Z-scores at the hip and lumbar spine. Data suggest the lifestyle of male jockeys’ compromise health more severely than females, possibly due to making-weight more frequently
Generalized Quantum Theory of Recollapsing Homogeneous Cosmologies
A sum-over-histories generalized quantum theory is developed for homogeneous
minisuperspace type A Bianchi cosmological models, focussing on the particular
example of the classically recollapsing Bianchi IX universe. The decoherence
functional for such universes is exhibited. We show how the probabilities of
decoherent sets of alternative, coarse-grained histories of these model
universes can be calculated. We consider in particular the probabilities for
classical evolution defined by a suitable coarse-graining. For a restricted
class of initial conditions and coarse grainings we exhibit the approximate
decoherence of alternative histories in which the universe behaves classically
and those in which it does not. For these situations we show that the
probability is near unity for the universe to recontract classically if it
expands classically. We also determine the relative probabilities of
quasi-classical trajectories for initial states of WKB form, recovering for
such states a precise form of the familiar heuristic "J d\Sigma" rule of
quantum cosmology, as well as a generalization of this rule to generic initial
states.Comment: 41 pages, 4 eps figures, revtex 4. Modest revisions throughout.
Physics unchanged. To appear in Phys. Rev.
Nonlinear model predictive control for improved water recovery and throughput stability for tailings reprocessing
The reprocessing of tailings aims to recover residual wealth, reclaim or rehabilitate valuable land, or mitigate safety and environmental risks. These aims all support environmental, social, and governance measures that are increasingly placed at the centre of corporate strategy. Tailings reprocessing operations are water intensive, and typically include surge tanks with both level and density averaging objectives to improve the efficiency of downstream water and mineral recovery. In this study, a rigorous dynamic model is derived to describe the rate of change of both the volume and density in these surge tanks. By simulation with industrial data it is demonstrated that the significant input disturbances typical to tailings reprocessing circuits drive a gain inversion in the density model of the surge tank. Since conventional linear averaging control approaches are not ideally suited to deal with gain inversion and multivariable control objectives a nonlinear model predictive controller (NMPC) was derived and implemented on an industrial tailings reprocessing surge tank. Results show a 5 % improvement in water recovery from the plant tailings product, and a 27 % reduction in the standard deviation of the tailings product mass flow.http://www.elsevier.com/locate/conengprachj2023Electrical, Electronic and Computer Engineerin
Gauge vs. Gravity mediation in models with anomalous U(1)'s
In an attempt to implement gauge mediation in string theory, we study string
effective supergravity models of supersymmetry breaking, containing anomalous
gauge factors. We discuss subtleties related to gauge invariance and the
stabilization of the Green-Schwarz moduli, which set non-trivial constraints on
the transmission of supersymmetry breaking to MSSM via gauge interactions.
Given those constraints, it is difficult to obtain the dominance of gauge
mediation over gravity mediation. Furthermore, generically the gauge
contributions to soft terms contain additional non-standard terms coming from
D-term contributions. Motivated by this, we study the phenomenology of recently
proposed hybrid models, where gravity and gauge mediations compete at the GUT
scale, and show that such a scenario can respect WMAP constraints and would be
easily testable at LHC.Comment: 40 pages, 5 figure
Towards an access economy model for industrial process control : a bulk tailings treatment plant case study
A nonlinear model for the surge tank of Sibanye-Stillwater’s Platinum tailings treatment plant is derived and linearised. Three controllers (two classical feedback and one model predictive controller (MPC)) are presented for control of the plant, and it is shown that a decoupled proportional-integral (PI) control structure, as would be employed in practice, performs the worst, while a nonlinear MPC controller provides the best performance. To illustrate an access economy model concept for industrial process control, a cloud platform to facilitate the competition between various controllers is presented and a scenario given with the three controllers competing to control the surge tank process. The platform is shown to provide the plant access to a controller that performs better than what is available locally.https://www.journals.elsevier.com/ifac-papersonlineam2022Electrical, Electronic and Computer Engineerin
Locating current sheets in the solar corona
Current sheets are essential for energy dissipation in the solar corona, in
particular by enabling magnetic reconnection. Unfortunately, sufficiently thin
current sheets cannot be resolved observationally and the theory of their
formation is an unresolved issue as well. We consider two predictors of coronal
current concentrations, both based on geometrical or even topological
properties of a force free coronal magnetic field. First, there are
separatrices related to magnetic nulls. Through separatrices the magnetic
connectivity changes discontinuously. Coronal magnetic nulls are, however, very
rare. At second, inspired by the concept of generalized magnetic reconnection
without nulls, quasi-separatrix layers (QSL) were suggested. Through QSL the
magnetic connectivity changes continuously, though strongly. The strength of
the connectivity change can be quantified by measuring the squashing of the
flux tubes which connect the magnetically conjugated photospheres.
We verify the QSL and separatrix concepts by comparing the sites of magnetic
nulls and enhanced squashing with the location of current concentrations in the
corona. Due to the known difficulties of their direct observation we simulated
the coronal current sheets by numerically calculating the response of the
corona to energy input from the photosphere heating a simultaneously observed
EUV Bright Point. We did not find coronal current sheets not at the
separatrices but at several QSL locations. The reason is that although the
geometrical properties of force free extrapolated magnetic fields can indeed,
hint at possible current concentrations, a necessary condition for current
sheet formation is the local energy input into the corona
- …