Note. Destruction of Marine Flora and Fauna in Fiji Caused by the Hurricane of February 1965

Volume: 20Start Page: 137End Page: 14

What is a pilot or feasibility study? A review of current practice and editorial policy

Background: In 2004, a review of pilot studies published in seven major medical journals during 2000-01 recommended that the statistical analysis of such studies should be either mainly descriptive or focus on sample size estimation, while results from hypothesis testing must be interpreted with caution. We revisited these journals to see whether the subsequent recommendations have changed the practice of reporting pilot studies. We also conducted a survey to identify the methodological components in registered research studies which are described as 'pilot' or 'feasibility' studies. We extended this survey to grant-awarding bodies and editors of medical journals to discover their policies regarding the function and reporting of pilot studies. Methods: Papers from 2007-08 in seven medical journals were screened to retrieve published pilot studies. Reports of registered and completed studies on the UK Clinical Research Network (UKCRN) Portfolio database were retrieved and scrutinized. Guidance on the conduct and reporting of pilot studies was retrieved from the websites of three grant giving bodies and seven journal editors were canvassed. Results: 54 pilot or feasibility studies published in 2007-8 were found, of which 26 (48%) were pilot studies of interventions and the remainder feasibility studies. The majority incorporated hypothesis-testing (81%), a control arm (69%) and a randomization procedure (62%). Most (81%) pointed towards the need for further research. Only 8 out of 90 pilot studies identified by the earlier review led to subsequent main studies. Twelve studies which were interventional pilot/feasibility studies and which included testing of some component of the research process were identified through the UKCRN Portfolio database. There was no clear distinction in use of the terms 'pilot' and 'feasibility'. Five journal editors replied to our entreaty. In general they were loathe to publish studies described as 'pilot'. Conclusion: Pilot studies are still poorly reported, with inappropriate emphasis on hypothesis-testing. Authors should be aware of the different requirements of pilot studies, feasibility studies and main studies and report them appropriately. Authors should be explicit as to the purpose of a pilot study. The definitions of feasibility and pilot studies vary and we make proposals here to clarify terminology

The airflow distortion at instruments sites on the RRS "James Cook"

Wind speed and air-sea flux measurements made from instrumentation on ships are affected by the airflow distortion created by the presence of the ship. The airflow can be eitheraccelerated or decelerated depending on the shape of the ship and the location of the anemometer. The computational fluid dynamics (CFD) package VECTIS was used to examinethe extent of the flow distortion at potential anemometer locations on the foremast platform of the RRS "James Cook". This technique has been previously used to study the airflow over many research ships, but this is believed to be the first time it has been applied to a research ship in the design/build stage.CFD modelling of the airflow over the ship showed that the foremast platform of the RRS "James Cook" is a good location to locate instrumentation and make high quality air-sea flux measurements. The wind speed is decelerated by about 2 % of the freestream wind speed for bow-on flows at well-exposed anemometer sites on the foremast platform. For relative wind directions up to ±30° of the bow the airflow is accelerated by up to 5 %.The ship’s anemometers are located on the main mast and are relatively close to the ship’s large satellite communication radome. For winds within 15° of the bow the wind speeds at these anemometer sites are accelerated by up to about 7 %. For wind directions at ±30° the satellite radome has a significant effect on the flow and the wind speeds will be severely biased, with the magnitude of the bias varying rapidly with wind direction and the angle of pitch of the ship. It is strongly recommended that these anemometers be moved higher up and further away from the mast

4f spin density in the reentrant ferromagnet SmMn2Ge2

The spin contribution to the magnetic moment in SmMn2Ge2 has been measured by magnetic Compton scattering in both the low and high temperature ferromagnetic phases. At low temperature, the Sm site is shown to possess a large 4f spin moment of 3.4 +/- 0.1 Bohr magnetons, aligned antiparallel to the total magnetic moment. At high temperature, the data show conclusively that ordered magnetic moments are present on the samarium site.Comment: 5 pages, 2 figures, transferred from PRL to PRB (Rapid Comm.

Shape Invariance and Its Connection to Potential Algebra

Exactly solvable potentials of nonrelativistic quantum mechanics are known to be shape invariant. For these potentials, eigenvalues and eigenvectors can be derived using well known methods of supersymmetric quantum mechanics. The majority of these potentials have also been shown to possess a potential algebra, and hence are also solvable by group theoretical techniques. In this paper, for a subset of solvable problems, we establish a connection between the two methods and show that they are indeed equivalent.Comment: Latex File, 10 pages, One figure available on request. Appeared in the proceedings of the workshop on "Supersymmetric Quantum Mechanics and Integrable Models" held at University of Illinois, June 12-14, 1997; Ed. H. Aratyn et a

Portland Stone: a nomination for "Global Heritage Stone Resource" from the United Kingdom

Portland Stone, a well known ooidal limestone of Jurassic age from the United Kingdom is here nominated as a suitable "Global Heritage Stone Resource". Portland Stone is considered to ideally fit the newly proposed designation as it has been utilised since Roman times in England and since the Middle Ages in the construction of major historic buildings including St Pauls Cathedral, British Museum and Bank of England in London. It was also the preferred building stone of Sir Christopher Wren, England's most famous architect. The international use of Portland Stone during the 20th century includes the United Nations building in New York City and the war graves of British and British Commonwealth soldiers. Portland Stone also continues to be quarried today in an environmentally sensitive manner whilst coastal outcrops of the material form a part of the "Dorset and East Devon Coast" World Heritage area (aka The Jurassic Heritage Coast)

A gamma- and X-ray detector for cryogenic, high magnetic field applications

As part of an experiment to measure the spectrum of photons emitted in beta-decay of the free neutron, we developed and operated a detector consisting of 12 bismuth germanate (BGO) crystals coupled to avalanche photodiodes (APDs). The detector was operated near liquid nitrogen temperature in the bore of a superconducting magnet and registered photons with energies from 5 keV to 1000 keV. To enlarge the detection range, we also directly detected soft X-rays with energies between 0.2 keV and 20 keV with three large area APDs. The construction and operation of the detector is presented, as well as information on operation of APDs at cryogenic temperatures