Lesiones musculoesqueléticas de extremidades superiores en trabajadores de una fábrica de cartón

Objective: Determine the relationship between musculoskeletal disorders of the upper extremities and work activities carried out by workers in cardboard boxes printing lines.Methods: Correlational and transversal study. Population of study 50 workers of printing lines of cardboard boxes. We used the Kuorinka Nordic questionnaire, clinical history, maneuvers and specific signs of upper limb and RULA method.Results: The results of the Nordic questionnaire show first of all symptomatology in dolls with 58%. The maneuvers and specific clinical signs most frequently reported as positive were Jobe, Gerber, Phalen, Finkelstein and Flick. The RULA method yielded a level 4 risk in all the positions with action of urgent changes in the tasks.Conclusions: The work activities carried out in the carton printing line are related to the symptomatology and generation of musculoskeletal injuries in upper extremities in the study population.Objetivo: Determinar la relación entre trastornos musculoesqueléticos de extremidades superiores y las actividades laborales realizadas por trabajadores de líneas de impresión de cajas de cartón.Métodos: Estudio correlacional y transversal. Población de estudio 50 trabajadores de líneas de impresión de cajas de cartón. Se utilizó el cuestionario nórdico de Kuorinka, historia clínica, maniobras y signos específicos de extremidad superior, análisis ergonómico del puesto de trabajo y método RULA.Resultados: Los resultados del cuestionario nórdico muestran en primer lugar sintomatología en muñecas con un 58%. Las maniobras y signos clínicos específicos con mayor frecuencia reportados como positivos fueron Jobe, Gerber, Phalen, Finkelstein y Flick. El método RULA arrojó un nivel riesgo 4 de 4 en todos los puestos con actuación de cambios urgentes en las tareas.Conclusiones: Las actividades laborales que realizan en la línea de impresión de cajas de cartón están relacionadas con la sintomatología y generación de lesiones muscuoloesqueléticas en extremidades superiores en la población de estudio

Efecto antibacteriano in vitro del extracto etanólico de las raíces de zingiber officinale roscoe (kion) y cúrcuma longa l. (palillo) frente a cepas de staphylococcus aureus

El objetivo del trabajo fue determinar la actividad antibacteriana in vitro del extracto etanólico de las raíces de Zingiber officinale roscoe (Kion) y Cúrcuma longa L. (Palillo) frente a cepas de Staphylococcus aureus, mediante el método de macrodilucion (MIC). La muestra fue recolectada en la ciudad de Chanchamayo, provincia de Chanchamayo, departamento de Junín. Se identificó taxonómicamente en el museo de historia natural de la Universidad mayor de San Marcos, según el sistema de Clasificación de Cronquist (1988)

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In CdS/CdTe solar cells, chemical interdiffusion at the interface gives rise to the formation of an interlayer of the ternary compound CdSxCdTe1-x. In this work, we evaluate the effects of this interlayer in CdS/CdTe photovoltaic cells in order to improve theoretical results describing experimental C-V (capacitance versus voltage) characteristics. We extended our previous theoretical methodology developed on the basis of three cardinal equations (Castillo-Alvarado et al., 2010). The present results provide a better fit to experimental data obtained from CdS/CdTe solar cells grown in our laboratory by the chemical bath deposition (for CdS film) and the close-spaced vapor transport (for CdTe film) techniques

Nonferrous waste foundry sand and milling fly ash as alternative low mechanical strength materials for construction industry: effect on mortars at early ages

An alternative solution to reduce environmental pollution using aluminum waste foundry sand (AWFS) and fly ash (FA) to produce sustainable construction materials was studied. New mortars were prepared by partially replacing ordinary Portland cement with fly ash at 5, 10 and 15 % mass. and a total replace of Ottawa sand (OS) with AWFS. The specimens were cured at 25°C with a 100% relative humidity. The mechanical behavior was evaluated by compression test at the ages of 7, 14 and 28 days. The microstructural characteristics were analyzed by scanning electron microscopy (SEM). The results indicate that the addition of milling fly ash in AWFS mortars increases the mechanical resistance, mostly at 5% mass reaching the maximum value of 10 MPa at 28 days of age. Microstructurally, it was found a porous cement matrix with some cracking caused by the reaction of portland cement with the metallic aluminum remaining in the waste sand, which is correlated to the low mechanical resistance obtained. The final mechanical characteristic makes this new product a serious candidate to be used as a sustainable building material working at low load

Cumulative acquisition of pathogenicity islands has shaped virulence potential and contributed to the emergence of LEE-negative Shiga toxinproducing Escherichia coli strains

Shiga toxin-producing Escherichia coli (STEC) are foodborne pathogens causing severe gastroenteritis, which may lead to hemolytic uremic syndrome. The Locus of Enterocyte Effacement (LEE), a Pathogenicity Island (PAI), is a major determinant of intestinal epithelium attachment of a group of STEC strains; however, the virulence repertoire of STEC strains lacking LEE, has not been fully characterized. The incidence of LEE-negative STEC strains has increased in several countries, highlighting the relevance of their study. In order to gain insights into the basis for the emergence of LEE-negative STEC strains, we performed a large-scale genomic analysis of 367 strains isolated worldwide from humans, animals, food and the environment. We identified uncharacterized genomic islands, including two PAIs and one Integrative Conjugative Element. Additionally, the Locus of Adhesion and Autoaggregation (LAA) was the most prevalent PAI among LEE-negative strains and we found that it contributes to colonization of the mice intestine. Our comprehensive and rigorous comparative genomic and phylogenetic analyses suggest that the accumulative acquisition of PAIs has played an important, but currently unappreciated role, in the evolution of virulence in these strains. This study provides new knowledge on the pathogenicity of LEE-negative STEC strains and identifies molecular markers for their epidemiological surveillance.This study was supported by FONDECYT grant 1161161 to R. Vidal and CONICYT-PCHA/2014-63140238 fellowship to D. Montero. Work at USC-LREC was supported by Project PI16/01477 from Plan Estatal de I+D+I 2013-2016, Instituto de Salud Carlos III, Subdirección General de Evaluación y Fomento de la Investigación and FEDER, Ministerio de Economia, Industria y Competitividad, Gobierno de España and Project ED431C 2017/57 from the Consellería de Cultura, Educación e Ordenación Universitaria, Xunta de Galicia and FEDER. Fondecyt 11150966 to Felipe Del Canto. Consejo Nacional de Ciencia y Tecnología; [Fondo Nacional de Desarrollo Científico y Tecnológico].S

Perfusion Decellularization of Extrahepatic Bile Duct Allows Tissue-Engineered Scaffold Generation by Preserving Matrix Architecture and Cytocompatibility

Reconstruction of bile ducts damaged remains a vexing medical problem. Surgeons have few options when it comes to a long segment reconstruction of the bile duct. Biological scaffolds of decellularized biliary origin may offer an approach to support the replace of bile ducts. Our objective was to obtain an extracellular matrix scaffold derived from porcine extrahepatic bile ducts (dECM-BD) and to analyze its biological and biochemical properties. The efficiency of the tailored perfusion decellularization process was assessed through histology stainings. Results from 4’-6-diamidino-2-phenylindole (DAPI), Hematoxylin and Eosin (H&E) stainings, and deoxyribonucleic acid (DNA) quantification showed proper extracellular matrix (ECM) decellularization with an effectiveness of 98%. Immunohistochemistry results indicate an effective decrease in immunogenic marker as human leukocyte antigens (HLA-A) and Cytokeratin 7 (CK7) proteins. The ECM of the bile duct was preserved according to Masson and Herovici stainings. Data derived from scanning electron microscopy (SEM) and thermogravimetric analysis (TGA) showed the preservation of the dECM-BD hierarchical structures. Cytotoxicity of dECM-BD was null, with cells able to infiltrate the scaffold. In this work, we standardized a decellularization method that allows one to obtain a natural bile duct scaffold with hierarchical ultrastructure preservation and adequate cytocompatibility

Impacto de la implementación del aprendizaje basado en problemas en combinación con las prácticas de laboratorio clínico y virtual de Fisiopatología para el desarrollo de competencias profesionales

Sección Deptal. de Fisiología (Farmacia)Fac. de FarmaciaFALSEsubmitte