958 research outputs found
Kinetics of catalysis with surface disorder
We study the effects of generalised surface disorder on the monomer-monomer
model of heterogeneous catalysis, where disorder is implemented by allowing
different adsorption rates for each lattice site. By mapping the system in the
reaction-controlled limit onto a kinetic Ising model, we derive the rate
equations for the one and two-spin correlation functions. There is good
agreement between these equations and numerical simulations. We then study the
inclusion of desorption of monomers from the substrate, first by both species
and then by just one, and find exact time-dependent solutions for the one-spin
correlation functions.Comment: LaTex, 19 pages, 1 figure included, requires epsf.st
Transition from electron accumulation to depletion at InGaN surfaces
The composition dependence of the Fermi-level pinning at the oxidized (0001) surfaces of n-type InxGa1−xN films (0<=x<=1) is investigated using x-ray photoemission spectroscopy. The surface Fermi-level position varies from high above the conduction band minimum (CBM) at InN surfaces to significantly below the CBM at GaN surfaces, with the transition from electron accumulation to depletion occurring at approximately x=0.3. The results are consistent with the composition dependence of the band edges with respect to the charge neutrality level
Retinopathy predicts progression of fasting plasma glucose: An Early Diabetes Intervention Program (EDIP) analysis
Background
Retinopathy is increasingly recognized in prediabetic populations, and may herald increased risk of metabolic worsening. The Early Diabetes Intervention Program (EDIP) evaluated worsening of glycemia in screen-detected Type 2 diabetes, following participants for up to 5 years. Here we have evaluated whether the presence of retinopathy at the time of detection of diabetes was associated with accelerated progression of glycemia.
Methods
We prospectively studied 194 participants from EDIP with available baseline retinal photographs. Retinopathy was determined at baseline using 7-field fundus photography and defined as an Early Treatment of Diabetic Retinopathy Study Scale grading score of ≥ 20.
Results
At baseline, 12% of participants had classical retinal lesions indicating retinopathy. In univariate Cox proportional hazard analysis, the presence of retinopathy at baseline was associated with a doubled risk of progression of fasting plasma glucose (HR 2.02; 95% CI 1.05–3.89). The retinopathy effect was robust to individual adjustment for age and glucose, the most potent determinants of progression in EDIP.
Conclusion
Retinopathy was associated with increased risk of progression of fasting plasma glucose among adults with screen-detected, early diabetes. Early detection of retinopathy may help individualize more aggressive therapy to prevent progressive metabolic worsening in early diabetes
Heterogeneous Catalysis on a Disordered Surface
We introduce a simple model of heterogeneous catalysis on a disordered
surface which consists of two types of randomly distributed sites with
different adsorption rates. Disorder can create a reactive steady state in
situations where the same model on a homogeneous surface exhibits trivial
kinetics with no steady state. A rich variety of kinetic behaviors occur for
the adsorbate concentrations and catalytic reaction rate as a function of model
parameters.Comment: 4 pages, gzipped PostScript fil
Corner Exponents in the Two-Dimensional Potts Model
The critical behavior at a corner in two-dimensional Ising and three-state
Potts models is studied numerically on the square lattice using transfer
operator techniques. The local critical exponents for the magnetization and the
energy density for various opening angles are deduced from finite-size scaling
results at the critical point for isotropic or anisotropic couplings. The
scaling dimensions compare quite well with the values expected from conformal
invariance, provided the opening angle is replaced by an effective one in
anisotropic systems.Comment: 11 pages, 2 eps-figures, uses LaTex and eps
The three species monomer-monomer model: A mean-field analysis and Monte Carlo study
We study the phase diagram and critical behavior of a one dimensional three
species monomer-monomer surface reaction model. Static Monte Carlo simulations
show a phase diagram consisting of a reactive steady state bordered by three
equivalent unreactive phases where the surface is saturated with one monomer
species. The transitions from the reactive to saturated phases are all
continuous, while the transitions between poisoned phases are first-order, with
bicritical points where the reactive phase meets two poisoned phases. A
mean-field cluster analysis predicts all of the qualitative features of the
phase diagram only when correlations up to triplets of adjacent sites are
included. Dynamic Monte Carlo simulations show that the transition from the
reactive to a saturated phase show critical behavior in the directed
percolation universality class, while the bicritical point shows critical
behavior in the even branching annihilating random walk class. The crossover
from bicritical to critical behavior is also studied.Comment: 16 pages using RevTeX, plus 10 figures. Uses psfig.st
Implementation of a hospital-wide multidisciplinary blunt chest injury care bundle (ChIP): Fidelity of delivery evaluation
BackgroundIneffective intervention for patients with blunt chest wall injury results in high rates of morbidity and mortality. To address this, a blunt chest injury care bundle protocol (ChIP) was developed, and a multifaceted plan was implemented using the Behaviour Change Wheel.ObjectiveThe purpose of this study was to evaluate the reach, fidelity, and dose of the ChIP intervention to discern if it was activated and delivered to patients as intended at two regional Australian hospitals.MethodsThis is a pretest and post-test implementation evaluation study. The proportion of ChIP activations and adherence to ChIP components received by eligible patients were compared before and after intervention over a 4-year period. Sample medians were compared using the nonparametric median test, with 95% confidence intervals. Differences in proportions for categorical data were compared using the two-sample z-test.Results/findingsOver the 19-month postimplementation period, 97.1% (n = 440) of eligible patients received ChIP (reach). The median activation time was 134 min; there was no difference in time to activation between business hours and after-hours; time to activation was not associated with comorbidities and injury severity score. Compared with the preimplementation group, the postimplementation group were more likely to receive evidence-based treatments (dose), including high-flow nasal cannula use (odds ratio [OR] = 6.8 [95% confidence interval {CI} = 4.8-9.6]), incentive spirometry in the emergency department (OR = 7.5, [95% CI = 3.2-17.6]), regular analgesia (OR = 2.4 [95% CI = 1.5-3.8]), regional analgesia (OR = 2.8 [95% CI = 1.5-5.3]), patient-controlled analgesia (OR = 1.8 [95% CI = 1.3-2.4]), and multiple specialist team reviews, e.g., surgical review (OR = 9.9 [95% CI = 6.1-16.1]).ConclusionsHigh fidelity of delivery was achieved and sustained over 19 months for implementation of a complex intervention in the acute context through a robust implementation plan based on theoretical frameworks. There were significant and sustained improvements in care practices known to result in better patient outcomes. Findings from this evaluation can inform future implementation programs such as ChIP and other multidisciplinary interventions in an emergency or acute care context
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