173 research outputs found

    The Development of an On-Line Learning and Teaching Resource for the Socio-Centric Aspects of Sustainable Design

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    This paper fits into the topics of socially relevant design, design and emotion and sustainable design and explores the question how can we create a more sustainable way of life? The paper also addresses the central theme of the conference – Design Education – creating a better world. This paper reports on the next phase in the development of a web-based learning and teaching resource specifically aimed at the socio-centric dimension of sustainable design which can be found at www.sociocenticdesign.com . A more extensive literature review was conducted, of which a summary is presented, however, the focus is on the outcomes learned from the collection of further primary data. It is confirmed that there is strong dominance by the techno and eco-centric dimensions and that there is a lack of awareness of the socio-centric dimension. It is concluded that being sustainable in design actually is about leaving the final design to later; it means that first and foremost sustainable design is to consider the designs purpose and its effects on the user, the community and society as a whole. An evaluation of two existing web-based resources, that focus on eco-design, was also conducted and informed the outcomes presented in this paper. The paper sets outs in some detail the content, arrangement and suggested web-interfaces for the new learning resource focused on the socio-centric dimension. The content is arranged into the following sections based upon the recommendations generated by Conrad: Past and Future; Time; People; Consumption, Design and Theories. The results of the research suggest that a high level of interactivity in the web-interface will be required

    Bromeliad tanks are unique habitats for microbial communities involved in methane turnover

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    The results indicate that every bromeliad tank is a unique island with respect to its resident microbial community. The presence of methanogens and active methanotrophs in all tank slurries further indicates the potential for both methane formation and methane oxidation.Max Planck Gesellschaft; LOEWE (Synmicro) Programm der hessischen Landesregierung zur Entwicklung wissenschaftlicher-ökonomischer Exzellenzresearc

    Drowning Prevention by Design

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    This paper presents an overview of an exploratory case study collaboration between Arts University Bournemouth (AUB) and the Royal National Lifeboat Institution (RNLI) in support of an RNLI delivery programme for international community management of drowning prevention in low-resource environments. The study focuses on the development of low-volume public rescue throw-lines that can be community made and maintained, the assembly and use of which are supported by a set of RNLI-developed instruction manuals intended for universal dissemination. The study examines the clarity of the instructions in the context of the makers’ interpretation of the manuals within the local constraints of Zanzibar. Preliminary findings indicate that these universally intended instruction manuals, in their current format, are open to interpretation, producing unsafe drowning prevention rescue lines that do not meet safety-critical standards. A re-design of the manuals through creative collaboration in a local context are the outcomes of this research. Discussion is also given as to whether a universal instruction manual should be the desirable outcome

    Process as prototype: exploring complex knowledge exchange in the production of low-cost buoyancy aids in Zanzibar through the participatory design of a ‘workflow system’

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    This paper reports on an investigation into the role of experiential knowledge in growing capacity for producing low-cost buoyancy aids with soft goods manufacturers – tailors – in Zanzibar, set within complex knowledge exchange collaborations under academic-industry partnerships. In this study, the makers' practice of tailoring and their local environment knowledge had a formative role in designing a prototype ‘workflow system’ for local, small-batch production of low-cost rescue throwlines as part of a wider community-led water safety programme. The study builds on a previous phase of the research that identified limitations with a human-centred design (HCD) approach to the creation of opensource instruction manuals for low volume production of rescue throwlines. We propose that the previously incumbent HCD approach through its problem-solving procedures obscured the importance of the local makers’ participation in the problematisation of the manufacturing process. By foregrounding the local makers’ knowledge of the whole manufacturing process, from sourcing materials in the market to making and testing the products, this study aimed to investigate how the local makers would devise and develop their own methodological approach to making the rescue throwline, examine what the findings would suggest for the design of the throwline, and explore how this knowledge might be exchanged with other collaborators in the project. A further and longer-term aim is to support the development and impact of local capacity building in end-to-end drowning prevention management by demonstrating the importance of experiential knowledge in existing local communities of makers. A participatory making approach informed by design thinking underpinned the design of the study. An experimental participant-led approach to the generation of data draws attention to the different positions and types of knowledge negotiated. The study elucidates some of the barriers for exchanging this critical experiential knowledge with collaborators and exposes challenges for creating new social infrastructure within the community concerning drowning prevention. It concludes that managing complex knowledge exchange in prototyping in the Zanzibar context requires an iterative methodological approach to the co-construction of knowledge centred around the experiential knowledge and skills of the users of the ‘workflow system’

    Determinants of functioning and health-related quality of life after vestibular stroke

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    BackgroundStroke accounts for 5–10% of all presentations with acute vertigo and dizziness. The objective of the current study was to examine determinants of long-term functioning and health-related quality of life (HRQoL) in a patient cohort with vestibular stroke.MethodsThirty-six patients (mean age: 66.1 years, 39% female) with an MRI-proven vestibular stroke were followed prospectively (mean time: 30.2 months) in the context of the EMVERT (EMergency VERTigo) cohort study at the Ludwig-Maximilians Universität, Munich. The following scores were obtained once in the acute stage (1 year after stroke): European Quality of Life Scale-five dimensions-five levels questionnaire (EQ-5D-5L) and Visual Analog Scale (EQ-VAS) for HRQoL, Dizziness Handicap Inventory (DHI) for symptom severity, and modified Rankin Scale (mRS) for general functioning and disability. Anxiety state and trait were evaluated by STAI-S/STAI-T, and depression was evaluated by the Patient Health Questionnaire-9 (PHQ-9). Voxel-based lesion mapping was applied in normalized MRIs to analyze stroke volume and localization. Multiple linear regression models were calculated to determine predictors of functional outcome (DHI, EQ-VAS at follow-up).ResultsMean DHI scores improved significantly from 45.0 in the acute stage to 18.1 at follow-up (p ConclusionThe average functional outcome of strokes with the chief complaint of vertigo and dizziness is favorable. The most relevant predictors for individual outcomes are the personal anxiety trait (especially in combination with the female sex), the initial symptom intensity, and lesion volume. These factors should be considered for therapeutic decisions both in the acute stage of stroke and during subsequent rehabilitation.</p

    Ethyl anthracene-9-carboxyl­ate

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    In the title compound, C17H14O2, the COO group and the anthracene fragment form a dihedral angle of 76.00 (19)°. The torsion angle around the O—Csp 3 bond of the ester group is 108.52 (18)°. The crystal structure is stabilized by C—H⋯O inter­actions and edge-to-face arene inter­actions with C—H⋯(ring centroid) distances in the range 2.75–2.84 Å

    Oral Carnosine Supplementation Prevents Vascular Damage in Experimental Diabetic Retinopathy

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    Backgrounds/Aims: Pericyte loss, vasoregression and neuroglial activation are characteristic changes in incipient diabetic retinopathy. In this study, the effect of the antioxidant and antiglycating dipeptide carnosine was studied on the development of experimental diabetic retinopathy. Materials/Methods: STZ-induced diabetic Wistar rats were orally treated with carnosine (1g/kg body weight/day). Retinal vascular damage was assessed by quantitative morphometry. Retinal protein extracts were analyzed for markers of oxidative stress, AGE-formation, activation of the hexosamine pathway and changes in the expression of Ang-2, VEGF and heat shock proteins Hsp27 and HO-1. Glial cell activation was analyzed using Western blot analysis and immunofluorescence of GFAP expression and retinal neuronal damage was histologically examined. Results: Oral carnosine treatment prevented retinal vascular damage after 6 months of experimental hyperglycemia. The protection was not caused by ROS-or AGE-inhibition, but associated with a significant induction of Hsp27 in activated glial cells and normalization of increased Ang-2 levels in diabetic retinas. A significant reduction of photoreceptors in retinas of carnosine treated animals was noted. Conclusion: Oral carnosine treatment protects retinal capillary cells in experimental diabetic retinopathy, independent of its biochemical function. The vasoprotective effect of carnosine might be mediated by the induction of protective Hsp27 in activated glial cells and normalization of hyperglycemia-induced Ang-2. Copyright (C) 2011 S. Karger AG, Basel</p

    Schlussbericht zum InnoProfile Forschungsvorhaben Methoden und Baustoffe zur nutzerorientierten Bausanierung

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    Nutzerorientierte Bausanierung bedeutet eine gegenüber dem konventionellen Vorgehen deutlich verstärkte Ausrichtung des Planungs- und Sanierungsprozesses auf die Anforderungen und Bedürfnisse des zukünftigen Nutzers eines Gebäudes. Dies hat einerseits ein hochwertigeres Produkt zum Ergebnis, erfordert andererseits aber auch den Einsatz neuer Methoden und Baustoffe sowie ein vernetztes Zusammenarbeiten aller am Bauprozess Beteiligten. Der Fokus der Publikation liegt dabei auf den Bereichen, die eine hohe Relevanz für die nutzerorientierte Bausanierung aufweisen. Dabei handelt es sich insbesondere um: Computergestütztes Bauaufmaß und digitale Bauwerksmodellierung (BIM), bauphysikalische Methoden zur Optimierung von Energieeffizienz und Behaglichkeit bei der Sanierung von Bestandsgebäuden, zerstörungsfreie Untersuchungsmethoden im Rahmen einer substanzschonenden Bauzustandsanalyse und Entwicklung von Ergänzungsbaustoffen. Das Projekt nuBau ist eine Kooperation zwischen den Fakultäten Bauingenieurwesen und Architektur der Bauhaus-Universität Weimar. Die beteiligten Professuren sind: Bauphysik, Informatik in der Architektur, Polymere Werkstoffe und Werkstoffe des Bauens

    Observation of Cosmic Ray Anisotropy with Nine Years of IceCube Data

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    Design of an Efficient, High-Throughput Photomultiplier Tube Testing Facility for the IceCube Upgrade

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