Nonalcoholic fatty liver disease prevalence in an Italian cohort of patients with hidradenitis suppurativa: A multi-center retrospective analysis

BACKGROUND Nonalcoholic fatty liver disease (NAFLD) includes two distinct conditions, with different histologic features and prognosis: non-alcoholic fatty liver (NAFL) and non-alcoholic steatohepatitis (NASH). Furthermore, NASH is the more aggressive necro-inflammatory form, which may accumulate fibrosis and result in End stage liver disease (ESLD). NAFLD is also linked to systemic inflammatory conditions such as psoriasis. NAFLD is currently the most common cause of ESLD in Western countries, becoming a serious public health concern. Hidradenitis suppurativa (HS) is a systemic inflammatory/autoinflammatory disease of the terminal follicular epithelium of the apocrine gland with a prevalence of 0.05% to 4.10%. Due to its systemic inflammatory behavior several comorbidities were recently associated, however liver ones were scarcely assessed. AIM To evaluate the prevalence and characteristics of NASH/NAFL in HS patients. METHODS This retrospective study is a sub-analysis of a larger study carried out in 4 Italian dermatological centers. In this cohort, there were 83 patients: 51 patients with HS only, 20 patients with HS/NAFL and 12 with HS/NASH. RESULTS Inflammatory comorbidities were present in 3.9% of HS only patients, 25% of HS/NAFL patients and 58.3% of HS/NASH patients (P < 0.001). Similarly, mean Autoinflammatory Disease Damage Index (ADDI) was significantly higher among patients with HS/NASH (5.3 ± 2.2, P < 0.001) compared to patients with HS/NAFL or HS only (2.8 ± 1.6 and 2.6 ± 1.4 respectively). Furthermore, ADDI correlates with IHS4 in HS, HS/NAFL and HS/NASH. Diabetic patients have higher Hurley score than not diabetic ones. Ultrasound examination was significantly different in the three groups. CONCLUSION HS patients displayed a high prevalence of NASH/NAFLD and ultrasound examination should be particularly addressed to patients that display high ADDI scores

Evaluation of the glycemic effect of methotrexate in psoriatic arthritis patients with metabolic syndrome: A pilot study

Methotrexate (MTX) is a systemic immunosuppressant drug used for the treatment of psoriasis and psoriatic arthritis. Previous studies demonstrated a potential association between psoriasis and diabetes mellitus, obesity, atherosclerosis, hypertension, eventuating into metabolic syndrome. This study aimed at exploring the glycemic effects of MTX in psoriatic arthritis (PsA) patients. In this prospective cross-sectional study, 27 patients with PsA were evaluated. The status of PsA and presence of accompanying metabolic syndrome was determined by standard criteria and indices. Blood indicators including HbA1c, erythrocyte sedimentation rate, fasting blood sugar, total cholesterol, high-density lipoprotein, triglycerides, and C-reactive protein were examined before and 12 weeks after MTX therapy. There were no significant changes between HbA1c levels before and after MTX therapy in both genders (men: P=0.131, women: P=0.803). In addition, HbA1c levels in PsA patients with metabolic syndrome were not different before and after treatment (P=0.250). Finally, HbA1c levels did not change in PsA patients without metabolic syndrome before and after therapy (P=0.506). MTX in PsA patients does not appear to have hyperglycaemic effects in the short-term and can be safely used in patients with metabolic syndrome and diabetes

'High dose' vs. 'medium dose' UVA1 phototherapy in italian patients with severe atopic dermatitis.

BACKGROUND The current evidences attest UVA1 phototherapy as effective in the treatment of severe atopic dermatitis (AD). Furthermore, in this indication, 'medium dose' is as effective as 'high dose' regimen. To date, a randomized comparison study evaluating the effectiveness as well as safety of different UVA1 protocols in different skin types in the treatment of adult patients with severe AD is still lacking. OBJECTIVE The aim of the present study was to compare the safety and the efficacy of medium and high dose UVA1 either in fair or in dark skin types. METHODS Twenty-seven adult patients with severe AD were consecutively included in a randomized, controlled, open, two arms trial Severity of AD was determined by means of SCORAD index and clinical improvement was also monitored. A total of 13 out of 27 patients were treated with high dose (130 J/cm ) UVA1 protocol while 14 out of 27 patients received medium dose (60 J/cm ) UVA1 protocol. Phototherapy was performed five times weekly up to 3 weeks. Before and after UVA1 treatment each patient was evaluated for skin pigmentation through Melanin Index (MI) quantitative evaluation. RESULTS Skin status improved in all patients resulting in a reduction of SCORAD index in all groups. Our results demonstrated that among patients with darker skin types and higher MI, high dose UVA1 was significantly more effective than medium dose (P < 0.0001) while within the groups with skin type II, no significant differences between high and medium dose protocols were observed. CONCLUSION Our study, confirms previous observations that UVA1 phototherapy should be considered among the first approaches in the treatment of patients with severe generalized AD and also demonstrates that in darker skin types, high dose UVA1 phototherapy is more effective than medium dose in the treatment of adult patients with severe AD

Mixed Versus Pure Variants of Desmoplastic Melanoma

BackgroundDesmoplastic melanoma (DM) is a subvariant of spindle cell melanoma, accounting for less than 4% of all cutaneous melanomas. It occurs later in life and is associated with chronic sun exposure. Desmoplastic melanoma prognosis is considered more favorable than other variants, with lower rates of metastasis and higher survival. Recently, DM has been further subclassified into pure and mixed, calling into question surgical management and patient outcomes as well as viability of current nationwide databases without this distinction.MethodsWe identified all patients with a histopathologic diagnosis of DM from the Cleveland Clinic electronic melanoma database (n = 58) from 1997 to 2013. Clinical and histopathologic data were collected. Comparison in clinical variables was performed between patients who had pure (n = 15) and mixed (n = 43) variants of DM.ResultsThere were no differences in age, sex, location of lesion, Breslow depth, ulceration, or regression. Patients with mixed DM were more likely to have lymphovascular invasion (P = 0.03) compared with pure DM. There was no difference in performance of sentinel lymph node biopsy (P = 0.25) or sentinel lymph node positivity (P = 0.31) between the 2 groups. Recurrence was present in 13.3% of pure and 30.2% of mixed patients. Overall, Kaplan-Meier 3-year survival was 75% for pure and 80% for mixed DM (P = 0.53).ConclusionsPure and mixed DMs seem to have similar clinical characteristics and outcomes. This indicates that analysis of national datasets without this subclassification remains viable

Secukinumab Loss of Efficacy Is Perfectly Counteracted by the Introduction of Combination Therapy (Rescue Therapy): Data from a Multicenter Real-Life Study in a Cohort of Italian Psoriatic Patients That Avoided Secukinumab Switching

Since psoriasis (PsO) is a chronic inflammatory disease, patients may experience a drug failure also with very effective drugs (i.e., secukinumab) and, consequently, dermatologists have two therapeutic options: switching or perform a combination therapy (rescue therapy) to save the drug that had decreased its efficacy. At the moment no studies focused on combination/rescue therapy of secukinumab, so we performed a 52-weeks multicenter retrospective observational study that involved 40 subjects with plaque psoriasis that experienced a secondary failure and were treated with combination therapy (ciclosporin (n = 11), MTX (n = 15), NB-UVB (n = 7) and apremilast (n = 7)). After 16 weeks of rescue/combination therapy, PASI and a DLQI varied respectively from 8 [7.0&ndash;9.0] and 13 [12.0&ndash;15.0], to 3 [2.8&ndash;4.0] and 3 [2.0&ndash;3.3]), suggesting a significant improvement of daily functionality and quality of life. Results were maintained at 52 weeks. No side effects were experienced during the study. Secukinumab remains a safety and effective drug for PsO patients also in the IL-23 and JAK inhibitors era. The rescue therapy is a valid therapeutic option in case of secukinumab secondary failure

Diet-Related Phototoxic Reactions in Psoriatic Patients Undergoing Phototherapy: Results from a Multicenter Prospective Study

Vegans and vegetarians often consume foods containing photosensitizers capable of triggering phytophotodermatitis. The potential effect of vegan and vegetarian diets on the response of psoriatic patients undergoing phototherapy is not well characterized. We assessed clinical outcomes of vegan, vegetarian and omnivore adult psoriatic patients undergoing band ultraviolet B phototherapy (NB-UVB). In this multicenter prospective observational study, we enrolled 119 adult, psoriatic patients, of whom 40 were omnivores, 41 were vegetarians and 38 were vegans, with phototherapy indication. After determining the minimum erythemal dose (MED), we performed NB-UVB sessions for 8 weeks. The first irradiation dosage was 70.00% of the MED, then increased by 20.00% (no erythema) or by 10.00% (presence of erythema) until a maximum single dose of 3 J/cm2 was reached and constantly maintained. All the enrolled patients completed the 8 weeks of therapy. Severe erythema was present in 16 (42.11%) vegans, 7 (17.07%) vegetarians and 4 (10.00%) omnivores (p &lt; 0.01). MED was lowest among vegans (21.18 ± 4.85 J/m2), followed by vegetarians (28.90 ± 6.66 J/m2) and omnivores (33.63 ± 4.53 J/m2, p &lt; 0.01). Patients with severe erythema were more likely to have a high furocumarin intake (OR 5.67, 95% CI 3.74–8.61, p &lt; 0.01). Vegans consumed the highest amount of furocumarin-rich foods. A model examining erythema, adjusted for gender, age, skin type, MED, phototherapy type, number of phototherapies and furocumarin intake, confirmed that vegans had a lower number of treatments. Vegans had more frequent severe erythema from NB-UVB, even after adjustment of the phototherapy protocol for their lower MED. Assessing diet information and adapting the protocol for vegan patients may be prudent

Pruritus characteristics in a large Italian cohort of psoriatic patients

none368nononeDamiani, G.; Cazzaniga, S.; Conic, R.R.Z.; Naldi, L.; Griseta, V.; Miracapillo, A.; Azzini, M.; Mocci, L.; Michelini, M.; Offidani, A.; Bernardini, L.; Campanati, A.; Ricotti, G.; Giacchetti, A.; Norat, M.; Gualco, F.; Castelli, A.; Cuccia, A.; Diana, A.; Roncarolo, G.; Belli, M.A.; Baldassarre, M.A.; Santoro, G.; Vena, G.A.; Lo Console, F.; Filotico, R.; Mastrandrea, V.; Brunetti, B.; Musumeci, F.; Carrabba, E.; Dal Mas, P.; Annicchiarico, F.; Benvegn_u, B.; Spaziani, G.; Cusano, F.; Saletta Iannazzone, S.; Galluccio, A.; Pezza, M.; Marchesi, L.; Imberti, G.; Reseghetti, A.; Barbera, C.; Reggiani, M.; Lanzoni, A.; Patrizi, A.; Bardazzi, F.; Antonucci, A.; De Tommaso, S.; Wallnofer, W.; Ingannamorte, F.; Calzavara-Pinton, P.; Iannazzi, S.; Zane, C.; Capezzera, R.; Bassisi, S.; Rossi, M.T.; Altamura, V.; Vigl, W.; Nobile, C.; Aste, N.; Murgia, S.; Mugheddu, C.; Scuderi, G.; Baglieri, F.; Di Dio, C.; Cilioni Grilli, E.; Mastronardi, C.; Agnusdei, C.P.; Antrilli, A.; Aulisa, L.; Raimondo, U.; Scotto di Luzio, G.; Battarra, V.C.; Farro, P.; Plaitano, R.; Micali, G.; Musumeci, M.L.; Massimino, D.; Li Calzi, M.; La Greca, S.; Pettinato, M.; Sapienza, G.; Valenti, G.; De Giacomo, P.F.; Amico, .; Arcangeli, F.; Brunelli, D.; Ghetti, E.; Tulli, A.; Assi, G.; Amerio, P.; Laria, G.; Prestinari, F.; Spadafora, S.; Coppola, M.; Caresana, G.; Pezzarossa, E.; Felisi, C.; Donato, L.; Bertero, M.; Musso, L.; Pa lazzini, S.; Bruscino, P.; Agozzino, U.C.; Ottaviani, M.; Simoncini, C.; Virgili, A.; Osti, F.; Fabbri, P.; Volpi, W.; Caproni, M.; Lotti, T.; Prignano, F.; Buggiani, G.; Troiano, M.; Fenizi, G.; Altobella, A.; Amoruso, A.; Condello, M.; Goffredo, A.; Righini, M.G.; Alessandrini, F.; Satolli, F.; Zampetti, M.; Bertani, E.; Fossati, S.; Parodi, A.; Burlando, M.; Fiorucci, C.; Nigro, A.; Ghigliotti, G.; Massone, L.; Moise, G.M.; Serrai, M.; Cannata, G.; Campagnoli, A.M.; Daly, M.; Leporati, C.; Peila, R.; Filosa, G.; Bugatti, L.; Nicolini, M.; Nazzari, G.; Cestari, R.; Anastasio, F.; Larussa, F.M.; Pollice, N.; De Francesco, F.; Mazzocchetti, G.; Peris, K.; Fargnoli, M.C.; Di Cesare, A.; De Angelis, L.; Flati, G.; Biamonte, A.S.; Quarta, G.; Congedo, M.; Carcaterra, A.; Strippoli, D.; Fideli, D.; Marsili, F.; Celli, M.; Ceccarini, M.; Bachini, L.; D'Oria, M.; Schirripa, V.; De Filippi, C.; Martini, P.; Lapucci, E.; Mazzatenta, C.; Ghilardi, A.; Simonacci, M.; Bettacchi, A.; Gasco, R.; Zanca, A.; Battistini, S.; Dattola, S.; Vernaci, R.; Postorino, F.; Zampieri, P.F.; Padovan, C.; Gonz_alez Intchaurraga, M.A.; Ladurner, J.; Guarneri, B.; Cannav_o, S.; Manfr_e, C.; Borgia, F.; Puglisi Guerra, A.; Cattaneo, A.; Carrera, C.; Fracchiolla, C.; Mozzanica, N.; Prezzemolo, L.; Menni, S.; Lodi, A.; Martino, P.; Monti, M.; Mancini, L.; Sacrini, F.; Altomare, G.F.; Taglioni, M.; Lovati, C.; Mercuri, S.R.; Schiesari, G.; Giannetti, A.; Conti, A.; Lasagni, C.; Greco, M.; Ronsini, G.; Schianchi, S.; Fiorentini, C.; Niglietta, S.; Maglietta, R.; Padalino, C.; Crippa, D.; Pini, M.; Rossi, E.; Tosi, D.; Armas, M.; Ruocco, V.; Ayala, F.; Balato, N.; Gaudiello, F.; Cimmino, G.F.; Monfrecola, G.; Gallo, L.; Argenziano, G.; Fulgione, E.; Berruti, G.; Ceparano, S.; De Michele, I.; Giorgiano, D.; Leigheb, G.; Deledda, S.; Peserico, A.; Alaibac, M.; Piaserico, S.; Schiesari, L.; Dan, G.; Mattei, I.; Oro, E.; Aric_o, M.; Bongiorno, M.R.; Angileri, R.; Amato, S.; Todaro, F.; Milioto, M.; Bellastro, R.; Di Nuzzo, S.; De Panfilis, G.; Zanni, M.; Borroni, G.; Cananzi, R.; Brazzelli, V.; Lisi, P.; Stingeni, L.; Hansel, K.; Pierfelice, V.; Donelli, S.; Rastelli, D.; Gasperini, M.; Barachini, P.; Cecchi, R.; Bartoli, L.; Pavesi, M.; De Paola, S.; Corradin, M.T.; Ricciuti, F.; Piccirillo, A.; Viola, L.; Tataranni, M.; Mautone, M.G.; Lo Scocco, G.; Niccoli, M.C.; Brunasso Vernetti, A.M.G.; Gaddoni, G.; Resta, F.; Casadio, M.C.; Arcidiaco, M.C.; Luvar_a, M.C.; Albertini, G.; Di Lernia, V.; Guareschi, E.; Catrani, S.; Morri, M.; Amerio, P.; De Simone, C.; D'Agostino, M.; Agostino, I.; Calvieri, S.; Cantoresi, F.; Richetta, A.; Sorgi, P.; Carnevale, C.; Nicolucci, F.; Berardesca, E.; Ardig_o, M.; De Felice, C.; Gubinelli, E.; Talamonti, M.; Camplone, G.; Cruciani, G.; Riccardi, F.; Barbati, R.; Zumiani, G.; Pagani, W.; Malagoli, P.G.; Pellicano, R.; Donadio, D.; Di Vito, C.; Cottoni, F.; Montesu, M.A.; Pirodda, C.; Addis, G.; Marongiu, P.; Farris, A.; Cacciapuoti, M.; Verrini, A.; Desirello, G.; Gnone, M.; Fimiani, M.; Pellegrino, M.; Castelli, G.; Zappal_a, L.; Sesana, G.; Ingordo, V.; Vozza, E.; Di Giuseppe, D.; Fasciocco, D.; Nespoli, P.; Papini, M.; Cicoletti, M.; Bernengo, M.G.; Ortoncelli, M.; Bonvicino, A.; Capella, G.; Doveil, G.C.; Forte, M.; Peroni, A.; Salomone, B.; Savoia, P.; Pippione, M.; Zichichi, L.; Frazzitta, M.; De Luca, G.; Zumiani, G.; Tasin, L.; Simonetto, D.; Ros, S.; Trevisan, G.; Patamia, M.; Miertusova, S.; Patrone, P.; Frattasio, A.; Piccirillo, F.; La Spina, S.; Di Gaetano, L.; Marzocchi, V.; Motolese, A.; Venturi, C.; Gai, F.; Pasquinucci, S.; Bellazzi, R.M.; Silvestri, T.; Girolomoni, G.; Gisondi, P.; Veller Fornasa, C.; Trevisan, G.P.Damiani, Giulia; Cazzaniga, S.; Conic, R. R. Z.; Naldi, L.; Griseta, V.; Miracapillo, A.; Azzini, M.; Mocci, L.; Michelini, M.; Offidani, A.; Bernardini, L.; Campanati, A.; Ricotti, G.; Giacchetti, A.; Norat, M.; Gualco, F.; Castelli, A.; Cuccia, A.; Diana, A.; Roncarolo, G.; Belli, M. A.; Baldassarre, M. A.; Santoro, G.; Vena, G. A.; Lo Console, F.; Filotico, R.; Mastrandrea, V.; Brunetti, B.; Musumeci, F.; Carrabba, E.; Dal Mas, P.; Annicchiarico, F.; Benvegn_u, B.; Spaziani, G.; Cusano, F.; Saletta Iannazzone, S.; Galluccio, A.; Pezza, M.; Marchesi, L.; Imberti, G.; Reseghetti, A.; Barbera, C.; Reggiani, M.; Lanzoni, A.; Patrizi, A.; Bardazzi, F.; Antonucci, DIEGO ADRIAN; De Tommaso, S.; Wallnofer, W.; Ingannamorte, F.; Calzavara-Pinton, P.; Iannazzi, S.; Zane, C.; Capezzera, R.; Bassisi, S.; Rossi, M. T.; Altamura, V.; Vigl, W.; Nobile, C.; Aste, N.; Murgia, S.; Mugheddu, C.; Scuderi, Gianluca; Baglieri, F.; Di Dio, C.; Cilioni Grilli, E.; Mastronardi, C.; Agnusdei, C. P.; Antrilli, A.; Aulisa, L.; Raimondo, U.; Scotto di Luzio, G.; Battarra, V. C.; Farro, P.; Plaitano, R.; Micali, G.; Musumeci, M. L.; Massimino, D.; LI CALZI, Marco; La Greca, S.; Pettinato, M.; Sapienza, G.; Valenti, G.; De Giacomo, P. F.; Amico, .; Arcangeli, F.; Brunelli, Donatella; Ghetti, E.; Tulli, A.; Assi, G.; Amerio, P.; Laria, G.; Prestinari, F.; Spadafora, S.; Coppola, M.; Caresana, G.; Pezzarossa, E.; Felisi, C.; DI DONATO, Luca; Bertero, M.; Musso, L.; Pa lazzini, S.; Bruscino, P.; Agozzino, U. C.; Ottaviani, M.; Simoncini, Claudia; Virgili, A.; Osti, F.; Fabbri, Paolo; Volpi, W.; Caproni, M.; Lotti, T.; Prignano, F.; Buggiani, G.; Troiano, M.; Fenizi, G.; Altobella, A.; Amoruso, A.; Condello, M.; Goffredo, A.; Righini, M. G.; Alessandrini, F.; Satolli, F.; Zampetti, M.; Bertani, E.; Fossati, S.; Parodi, A.; Burlando, M.; Fiorucci, C.; Nigro, A.; Ghigliotti, G.; Massone, L.; Moise, G. M.; Serrai, M.; Cannata, G.; Campagnoli, A. M.; Daly, M.; Leporati, C.; Peila, R.; Filosa, G.; Bugatti, L.; Nicolini, M.; Nazzari, G.; Cestari, R.; Anastasio, F.; Larussa, F. M.; Pollice, N.; De Francesco, F.; Mazzocchetti, Gabriele; Peris, K.; Fargnoli, M. C.; Di Cesare, A.; DE ANGELIS, Luca; Flati, G.; Biamonte, A. S.; Quarta, G.; Congedo, M.; Carcaterra, A.; Strippoli, D.; Fideli, D.; Marsili, F.; Celli, Maria; Ceccarini, M.; Bachini, L.; D'Oria, M.; Schirripa, V.; De Filippi, C.; Martini, P.; Lapucci, E.; Mazzatenta, C.; Ghilardi, A.; Simonacci, M.; Bettacchi, A.; Gasco, R.; Zanca, A.; Battistini, S.; Dattola, S.; Vernaci, R.; Postorino, F.; Zampieri, P. F.; Padovan, C.; Gonz_alez Intchaurraga, M. A.; Ladurner, J.; Guarneri, B.; Cannav_o, S.; Manfr_e, C.; Borgia, F.; Puglisi Guerra, A.; Cattaneo, A.; Carrera, C.; Fracchiolla, C.; Mozzanica, N.; Prezzemolo, L.; Menni, S.; Lodi, A.; Martino, P.; Monti, Marina; Mancini, L.; Sacrini, F.; Altomare, G. F.; Taglioni, M.; Lovati, C.; Mercuri, S. R.; Schiesari, G.; Giannetti, Anna; Conti, A.; Lasagni, C.; Greco, M.; Ronsini, G.; Schianchi, S.; Fiorentini, C.; Niglietta, S.; Maglietta, R.; Padalino, C.; Crippa, D.; Pini, M.; Rossi, E.; Tosi, D.; Armas, M.; Ruocco, V.; Ayala, F.; Balato, N.; Gaudiello, F.; Cimmino, G. F.; Monfrecola, G.; Gallo, L.; Argenziano, G.; Fulgione, E.; Berruti, G.; Ceparano, S.; De Michele, I.; Giorgiano, D.; Leigheb, G.; Deledda, S.; Peserico, A.; Alaibac, M.; Piaserico, S.; Schiesari, L.; Dan, G.; Mattei, I.; Oro, E.; Aric_o, M.; Bongiorno, M. R.; Angileri, R.; D'Amato, Sonia; Todaro, F.; Milioto, M.; Bellastro, R.; Di Nuzzo, S.; De Panfilis, G.; Zanni, M.; Borroni, Giovanni Marco; Cananzi, R.; Brazzelli, V.; Lisi, P.; Stingeni, L.; Hansel, K.; Pierfelice, V.; Donelli, S.; Rastelli, D.; Gasperini, M.; Barachini, P.; Cecchi, R.; Bartoli, L.; Pavesi, M.; De Paola, S.; Corradin, M. T.; Ricciuti, F.; Piccirillo, A.; Viola, L.; Tataranni, M.; Mautone, M. G.; Lo Scocco, G.; Niccoli, M. C.; Brunasso Vernetti, A. M. G.; Gaddoni, G.; Resta, F.; Casadio, M. C.; Arcidiaco, M. C.; Luvar_a, M. C.; Albertini, G.; Di Lernia, V.; Guareschi, E.; Catrani, S.; Morri, M.; Amerio, P.; De Simone, C.; D'Agostino, M.; Agostino, I.; Calvieri, S.; Cantoresi, F.; Richetta, A.; Sorgi, P.; Carnevale, C.; Nicolucci, F.; Berardesca, E.; Ardig_o, M.; De Felice, C.; Gubinelli, E.; Talamonti, Marco Claudio; Camplone, G.; Cruciani, G.; Riccardi, F.; Barbati, R.; Zumiani, G.; Pagani, W.; Malagoli, P. G.; Pellicano, R.; Donadio, D.; Di Vito, C.; Cottoni, F.; Montesu, M. A.; Pirodda, C.; Addis, G.; Marongiu, P.; Farris, A.; Cacciapuoti, M.; Verrini, A.; Desirello, G.; Gnone, M.; Fimiani, M.; Pellegrino, M.; Castelli, G.; Zappal_a, L.; Sesana, G.; Ingordo, V.; Vozza, E.; Di Giuseppe, D.; Fasciocco, D.; Nespoli, P.; Papini, M.; Cicoletti, M.; Bernengo, M. G.; Ortoncelli, M.; Bonvicino, A.; Capella, G.; Doveil, G. C.; Forte, M.; Peroni, A.; Salomone, B.; Savoia, P.; Pippione, M.; Zichichi, L.; Frazzitta, M.; De Luca, G.; Zumiani, G.; Tasin, L.; Simonetto, D.; Ros, S.; Trevisan, G.; Patamia, M.; Miertusova, S.; Patrone, P.; Frattasio, A.; Piccirillo, F.; La Spina, S.; Di Gaetano, L.; Marzocchi, V.; Motolese, Alfonso; Venturi, C.; Gai, F.; Pasquinucci, S.; Bellazzi, R. M.; Silvestri, T.; Girolomoni, G.; Gisondi, P.; Veller Fornasa, C.; Trevisan, G. P