Natural and human-induced coastal dynamics at a back-barrier beach

This study contributes to the understanding of very low-energy fetch-limited environments by reporting the evolution of a back-barrier beach (Ancão Peninsula, southern Portugal). It considers two timescales: a large-scale evolution for the past 60 years based on aerial photograph analysis, and a small-scale beach evolution based on monthly topographic surveys performed during three years of monitoring. Each timescale revealed a different rate of evolution, the first reporting a modified beach response-type (from human activities), and the second reporting a natural beach response-type. Human activities caused significant changes in the back-barrier shore, whereas changes under natural forcing were much smaller, were less influential on the area's evolution, and were not sufficient to counteract or mask the consequences of human activities. The findings of the study should contribute to a better understanding about the large- and small- scale changes in other back-barriers characterised by similar very low-energy conditions.info:eu-repo/semantics/publishedVersio

Grassroots Agency: Participation and Conflict in Buenos Aires Shantytowns seen through the Pilot Plan for Villa 7 (1971–1975)

open access articleIn 1971, after more than a decade of national and municipal policies aimed at the top-down removal of shantytowns, the Buenos Aires City Council approved the Plan Piloto para la Relocalización de Villa 7 (Pilot Plan for the Relocation of Shantytown 7; 1971–1975, referred to as the Pilot Plan hereinafter). This particular plan, which resulted in the construction of the housing complex, Barrio Justo Suárez, endures in the collective memory of Argentines as a landmark project regarding grassroots participation in state housing initiatives addressed at shantytowns. Emerging from a context of a housing shortage for the growing urban poor and intense popular mobilizations during the transition to democracy, the authors of the Pilot Plan sought to empower shantytown residents in novel ways by: 1) maintaining the shantytown’s location as opposed to eradication schemes that relocated the residents elsewhere, 2) formally employing some of the residents for the stage of construction, as opposed to “self-help” housing projects in which the residents contributed with unpaid labor, and 3) including them in the urban and architectural design of the of the new housing. This paper will examine the context in which the Pilot Plan was conceived of as a way of re-assessing the roles of the state, the user, and housing-related professionals, often seen as antagonistic. The paper argues that residents’ fair participation and state intervention in housing schemes are not necessarily incompatible, and can function in specific social and political contexts through multiactor proposals backed by a political will that prioritizes grassroots agency

Choice of the initial antiretroviral treatment for HIV-positive individuals in the era of integrase inhibitors

BACKGROUND: We aimed to describe the most frequently prescribed initial antiretroviral therapy (ART) regimens in recent years in HIV-positive persons in the Cohort of the Spanish HIV/AIDS Research Network (CoRIS) and to investigate factors associated with the choice of each regimen. METHODS: We analyzed initial ART regimens prescribed in adults participating in CoRIS from 2014 to 2017. Only regimens prescribed in >5% of patients were considered. We used multivariable multinomial regression to estimate Relative Risk Ratios (RRRs) for the association between sociodemographic and clinical characteristics and the choice of the initial regimen. RESULTS: Among 2874 participants, abacavir(ABC)/lamivudine(3TC)/dolutegavir(DTG) was the most frequently prescribed regimen (32.1%), followed by tenofovir disoproxil fumarate (TDF)/emtricitabine (FTC)/elvitegravir(EVG)/cobicistat(COBI) (14.9%), TDF/FTC/rilpivirine (RPV) (14.0%), tenofovir alafenamide (TAF)/FTC/EVG/COBI (13.7%), TDF/FTC+DTG (10.0%), TDF/FTC+darunavir/ritonavir or darunavir/cobicistat (bDRV) (9.8%) and TDF/FTC+raltegravir (RAL) (5.6%). Compared with ABC/3TC/DTG, starting TDF/FTC/RPV was less likely in patients with CD4100.000 copies/mL. TDF/FTC+DTG was more frequent in those with CD4100.000 copies/mL. TDF/FTC+RAL and TDF/FTC+bDRV were also more frequent among patients with CD4<200 cells//muL and with transmission categories other than men who have sex with men. Compared with ABC/3TC/DTG, the prescription of other initial ART regimens decreased from 2014-2015 to 2016-2017 with the exception of TDF/FTC+DTG. Differences in the choice of the initial ART regimen were observed by hospitals' location. CONCLUSIONS: The choice of initial ART regimens is consistent with Spanish guidelines' recommendations, but is also clearly influenced by physician's perception based on patient's clinical and sociodemographic variables and by the prescribing hospital location

Effectiveness of an mHealth intervention combining a smartphone app and smart band on body composition in an overweight and obese population: Randomized controlled trial (EVIDENT 3 study)

Background: Mobile health (mHealth) is currently among the supporting elements that may contribute to an improvement in health markers by helping people adopt healthier lifestyles. mHealth interventions have been widely reported to achieve greater weight loss than other approaches, but their effect on body composition remains unclear. Objective: This study aimed to assess the short-term (3 months) effectiveness of a mobile app and a smart band for losing weight and changing body composition in sedentary Spanish adults who are overweight or obese. Methods: A randomized controlled, multicenter clinical trial was conducted involving the participation of 440 subjects from primary care centers, with 231 subjects in the intervention group (IG; counselling with smartphone app and smart band) and 209 in the control group (CG; counselling only). Both groups were counselled about healthy diet and physical activity. For the 3-month intervention period, the IG was trained to use a smartphone app that involved self-monitoring and tailored feedback, as well as a smart band that recorded daily physical activity (Mi Band 2, Xiaomi). Body composition was measured using the InBody 230 bioimpedance device (InBody Co., Ltd), and physical activity was measured using the International Physical Activity Questionnaire. Results: The mHealth intervention produced a greater loss of body weight (–1.97 kg, 95% CI –2.39 to –1.54) relative to standard counselling at 3 months (–1.13 kg, 95% CI –1.56 to –0.69). Comparing groups, the IG achieved a weight loss of 0.84 kg more than the CG at 3 months. The IG showed a decrease in body fat mass (BFM; –1.84 kg, 95% CI –2.48 to –1.20), percentage of body fat (PBF; –1.22%, 95% CI –1.82% to 0.62%), and BMI (–0.77 kg/m2, 95% CI –0.96 to 0.57). No significant changes were observed in any of these parameters in men; among women, there was a significant decrease in BMI in the IG compared with the CG. When subjects were grouped according to baseline BMI, the overweight group experienced a change in BFM of –1.18 kg (95% CI –2.30 to –0.06) and BMI of –0.47 kg/m2 (95% CI –0.80 to –0.13), whereas the obese group only experienced a change in BMI of –0.53 kg/m2 (95% CI –0.86 to –0.19). When the data were analyzed according to physical activity, the moderate-vigorous physical activity group showed significant changes in BFM of –1.03 kg (95% CI –1.74 to –0.33), PBF of –0.76% (95% CI –1.32% to –0.20%), and BMI of –0.5 kg/m2 (95% CI –0.83 to –0.19). Conclusions: The results from this multicenter, randomized controlled clinical trial study show that compared with standard counselling alone, adding a self-reported app and a smart band obtained beneficial results in terms of weight loss and a reduction in BFM and PBF in female subjects with a BMI less than 30 kg/m2 and a moderate-vigorous physical activity level. Nevertheless, further studies are needed to ensure that this profile benefits more than others from this intervention and to investigate modifications of this intervention to achieve a global effect

A multi-scale conceptual model of flood-tide delta morphodynamics in micro-tidal estuaries

Wave and tide induced sediment transport pathways and rates govern the morphological evolution of estuarine systems. An understanding of the morphodynamics of these systems is required to maintain their commercial, biological and recreational value. The morphodynamics of Port Stephens estuary, a micro-tidal estuary located on a wave dominated southeast coast of Australia were investigated using bathymetric surveys and current velocity data from several locations over the estuary. This provided detailed insight into the rates and direction of movement for the main sedimentary features of the system, and how these features interact with the processes that drive their evolution. We used these findings to develop a conceptual model for estuarine morphodynamics that accounts for fair weather and storm conditions. Our model explains how sediment eroded from the estuarine beaches is trapped by the adjacent flood-tide delta. The model is applicable to fetch-limited estuaries that do not have offshore sources of sediment, where the tidal currents are weak in relation to the incident ocean waves, and that have a wide, stable entrance through which ocean waves can propagate into the estuary. The model is multi-scale in that it encapsulates both short-term and local process, and large scale evolution of an estuary; therefore, it represents a tool that may be used in developing sustainable estuary management strategies

Platelet-rich plasma, rhOP-1 (rhBMP-7) and frozen rib allograft for the reconstruction of bony mandibular defects in sheep. A pilot experimental study.

A 6 cm bony defect in the mandible of 15 sheep, 8 years old, was reconstructed using variously allograft of frozen rib, rhOP-1 (rh BMP-7), platelet-rich plasma (PRP), and a combination of frozen rib allograft and rhOP-1. The histological, histomorphometric, immunohistochemical and radiographic features of reconstruction were analysed. The animals were euthanised at 2 months postoperatively. In the control and PRP groups, no bone formation was detected. The sheep receiving rhOP-1 showed some and those receiving both rhOP-1 and allograft showed most new bone formation; in both groups this was through endochondral and also fibrous ossification. The combination of bone allograft with growth factors demonstrated osteoconductive as well as osteoinductive properties, and is appealing in the management of problem fractures

Tracer studies on the updrift margin of a complex inlet system

Three sediment transport studies using tracers were performed at Anca˜o Inlet (southern Portugal). The objectives of the experiments were to understand the sediment transport pathways and to determine their magnitudes on the updrift margin of an inlet. In order to apply the traditionally used Space Integration Methodology to the tracer experiments, adaptations were required. The study area was divided into four morphologically defined sectors and this was found to be a key factor for the applicability of tracers in a complex area. The four sectors are as follows: sector A is the straight part of the updrift beach; sector B is the upper area of the swash platform; sector C is the lower area of the swash platform; and sector D represents the inner parts of the inlet margin. The integrated analysis of all collected data (forcing mechanisms, tracer distribution and topographic evolution) led to the determination of the sediment pathways. A semi-quantitative conceptual model was developed in order to explain the sediment transport pathways and magnitudes that a known mass of sediment would follow after arriving at the swash platform. It was found that the areas with the largest sediment accumulation were sectors B and C, while almost no sediment was retained in sector D, which experienced significant erosion. According to the model, 53% of the initial mass of sediments remain in the system after two tidal cycles. It is hypothesised that sediment losses are caused by sediment transport towards the ebb delta and by sediment bypassing occurring from the ebb delta to the downdrift beach through swash bar processes. The herein defined conceptual model represents a useful tool that could be applied to other tidal inlets under similar conditions, facilitating sediment budget studies around tidal inlets

A Multi-Scale Conceptual Model of Flood-Tide Delta Morphodynamics in Micro-Tidal Estuaries

Wave and tide induced sediment transport pathways and rates govern the morphological evolution of estuarine systems. An understanding of the morphodynamics of these systems is required to maintain their commercial, biological and recreational value. The morphodynamics of Port Stephens estuary, a micro-tidal estuary located on a wave dominated southeast coast of Australia were investigated using bathymetric surveys and current velocity data from several locations over the estuary. This provided detailed insight into the rates and direction of movement for the main sedimentary features of the system, and how these features interact with the processes that drive their evolution. We used these findings to develop a conceptual model for estuarine morphodynamics that accounts for fair weather and storm conditions. Our model explains how sediment eroded from the estuarine beaches is trapped by the adjacent flood-tide delta. The model is applicable to fetch-limited estuaries that do not have offshore sources of sediment, where the tidal currents are weak in relation to the incident ocean waves, and that have a wide, stable entrance through which ocean waves can propagate into the estuary. The model is multi-scale in that it encapsulates both short-term and local process, and large scale evolution of an estuary; therefore, it represents a tool that may be used in developing sustainable estuary management strategies