1,004 research outputs found

    Natpåfugleøje

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    Marcel Cohen: Natpåfugleøj

    Resumo da História da Escrita

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    A história da escrita, etapa e fator da história da humanidade, que oscila entre o econômico e o estético e tem sempre caráter social, é extremamente complexa . Não é possível seguí-la simplesmente no decurso do tempo, porque começou várias vêzes e em mais de um lugar.

    Opposition theory and computational semiotics

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    Opposition theory suggests that binary oppositions (e.g., high vs. low) underlie basic cognitive and linguistic processes. However, opposition theory has never been implemented in a computational cognitive-semiotics model. In this paper, we present a simple model of metaphor identification that relies on opposition theory. An algorithm instantiating the model has been tested on a data set of 100 phrases comprising adjective-noun pairs in which approximately a half represent metaphorical language-use (e.g., dark thoughts) and the rest literal language-use (e.g., dark hair). The algorithm achieved 89% accuracy in metaphor identification and illustrates the relevance of opposition theory for modelling metaphor processing

    Constructing Sublinear Expectations on Path Space

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    We provide a general construction of time-consistent sublinear expectations on the space of continuous paths. It yields the existence of the conditional G-expectation of a Borel-measurable (rather than quasi-continuous) random variable, a generalization of the random G-expectation, and an optional sampling theorem that holds without exceptional set. Our results also shed light on the inherent limitations to constructing sublinear expectations through aggregation.Comment: 28 pages; forthcoming in 'Stochastic Processes and their Applications

    Nanoscale Magnetic Imaging using Circularly Polarized High-Harmonic Radiation

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    This work demonstrates nanoscale magnetic imaging using bright circularly polarized high-harmonic radiation. We utilize the magneto-optical contrast of worm-like magnetic domains in a Co/Pd multilayer structure, obtaining quantitative amplitude and phase maps by lensless imaging. A diffraction-limited spatial resolution of 49 nm is achieved with iterative phase reconstruction enhanced by a holographic mask. Harnessing the unique coherence of high harmonics, this approach will facilitate quantitative, element-specific and spatially-resolved studies of ultrafast magnetization dynamics, advancing both fundamental and applied aspects of nanoscale magnetism.Comment: Ofer Kfir and Sergey Zayko contributed equally to this work. Presented in CLEO 2017 (Oral) doi.org/10.1364/CLEO_QELS.2017.FW1H.

    Commiphora gileadensis sap extract induces cell cycle-dependent death in immortalized keratinocytes and human dermoid carcinoma

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    We would like to dedicate this article to the memory of Professor Yoram Milner, who has passed away before this study was achieved. We are immeasurably indebted to him, professionally and personally. The study was supported by grants from the ICA Foundation and the Ministry of Science, Technology and Space.Peer reviewedPublisher PD

    Історія становлення міжнародного суду ООН

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    Досліджується історія розвитку міжнародного правосуддя та діяльності інституту судової системи на міжнародному рівні, особливості становлення Міжнародного Суду ООН та його попередниці Постійної Палати міжнародного правосуддя в рамках Ліги Націй.Исследуется история развития международного правосудия и деятельности института судебной системы на международном уровне, особенности становления Международного Суда ООН и его предшественника Постоянной Палаты международного правосудия в рамках Лиги Наций.In the article author explores the history of international justice and the judicial system of the institute on the international level.Feature of theformation International Court of Justice and its predecessor the Permanent Court of International Justice by the League of Nations

    Drivers of Tuberculosis Transmission.

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    Measuring tuberculosis transmission is exceedingly difficult, given the remarkable variability in the timing of clinical disease after Mycobacterium tuberculosis infection; incident disease can result from either a recent (ie, weeks to months) or a remote (ie, several years to decades) infection event. Although we cannot identify with certainty the timing and location of tuberculosis transmission for individuals, approaches for estimating the individual probability of recent transmission and for estimating the fraction of tuberculosis cases due to recent transmission in populations have been developed. Data used to estimate the probable burden of recent transmission include tuberculosis case notifications in young children and trends in tuberculin skin test and interferon γ-release assays. More recently, M. tuberculosis whole-genome sequencing has been used to estimate population levels of recent transmission, identify the distribution of specific strains within communities, and decipher chains of transmission among culture-positive tuberculosis cases. The factors that drive the transmission of tuberculosis in communities depend on the burden of prevalent tuberculosis; the ways in which individuals live, work, and interact (eg, congregate settings); and the capacity of healthcare and public health systems to identify and effectively treat individuals with infectious forms of tuberculosis. Here we provide an overview of these factors, describe tools for measurement of ongoing transmission, and highlight knowledge gaps that must be addressed

    Achieving UNAIDS 90-90-90 targets for pregnant and postpartum women in sub-Saharan Africa: progress, gaps and research needs

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    The implementation of the 2013 World Health Organization Option B+ recommendations for HIV treatment during pregnancy has helped drive significant progress in achieving universal treatment for pregnant and postpartum women in sub-Saharan Africa (SSA). Yet, critical research and implementation gaps exist in achieving the UNAIDS 90-90-90 targets. To help guide researchers, programmers and policymakers in prioritising these areas, we undertook a comprehensive review of the progress, gaps and research needs to achieve the 90-90-90 targets for this population in the Option B+ era, including early infant HIV diagnosis (EID) for HIV-exposed infants. Salient areas where progress has been achieved or where gaps remain include: (1) knowledge of HIV status is higher among people with HIV in southern and eastern Africa compared to western and central Africa (81% versus 48%, UNAIDS); (2) access to antiretroviral therapy (ART) for pregnant women has doubled in 22 of 42 SSA countries, but only six have achieved the second 90, and nearly a quarter of pregnant women initiating ART become lost to follow-up; (3) viral suppression data for this population are sparse (estimates range from 30% to 98% peripartum), with only half of women maintaining suppression through 12 months postpartum; and (4) EID rates range from 15% to 62%, with only three of 21 high-burden SSA countries testing >50% HIV-exposed infants within the first 2 months of life. We have identified and outlined promising innovations and research designed to address these gaps and improve the health of pregnant and postpartum women living with HIV and their infants

    Long-term effectiveness and prediction of treatment outcome in cognitive behavioral therapy and sertraline for late-life anxiety disorders

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    Background: Although anxiety disorders are prevalent in older adults, randomized controlled trials of treatment effectiveness for late-life anxiety are scarce and have focused primarily on the effectiveness of psychotherapeutic interventions. However, recent findings suggest that in some cases, pharmacological treatment may be more beneficial for late-life anxiety disorders. As yet, there have been no systematic studies investigating prognostic factors for the outcome of cognitive behavioral therapy (CBT) and pharmacotherapy for late-life anxiety. The objective of the present study was to study long-term treatment outcomes and to explore differential predictors for both short-term and long-term treatment outcomes of sertraline and CBT for late-life anxiety disorders. Methods: Participants of a randomized controlled trial (RCT) comparing sertraline and CBT for the treatment of late-life anxiety were contacted one year after completing their treatment, so that predictors for both short-term and long-term treatment outcome could be established. Results: Sertraline showed a greater reduction of symptoms than CBT on anxiety (Hamilton Anxiety Rating Scale; HARS) and worry (Worry Domain Questionnaire) ratings at one-year follow-up. The strongest predictor for short-term CBT outcome was poor perceived health, explaining 40% of the variance in post-treatment residual gain scores on the HARS. The strongest predictor for long-term CBT outcome was neuroticism, explaining 20% of the variance in residual gain scores at one-year follow-up. Analyses revealed no significant predictors for treatment outcome in sertraline participants. Conclusions: Our study suggests that long-term use of sertraline might be more beneficial for late-life anxiety than a 15-week CBT program. Poor perceived health and neuroticism are predictive of less improvement after CBT in anxious older adults. Implications of these findings are discussed
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