COVID-19 EM RECÉM-NASCIDOS: UMA REVISÃO DE LITERATURA

Em dezembro de 2019, houve um surto de uma nova doença infecciosa em Wuhan na província de Hubei na China. A doença do coronavírus 2019 (COrona VIrus Disease - COVID-19) é causada pelo sétimo coronavírus identificado: síndrome respiratória aguda grave do coronavírus 2 (SARS-CoV-2). Esse artigo tem como objetivo reunir o atual conhecimento disponível na literatura sobre a COVID-19 em recém-nascidos, com enfoque em epidemiologia, sinais e sintomas, resultados de testes diagnósticos, resultados de exames de imagem e desfecho neonatal. De acordo com estudos chineses, a probabilidade de transmissão intrauterina parece ser baixa. Crianças representam cerca de 2% dos casos de COVID-19 diagnosticados na China, 1,7% no Brasil e 1,2% na Itália. Neonatos nascidos de mães que testaram positivo para COVID-19, apresentaram dispneia, cianose, vômitos e intolerância alimentar, febre, taquicardia, gemidos e rash cutâneo. No exame tomográfico, o sinal do halo envolvendo consolidação é uma característica típica dos pacientes pediátricos, diferentemente do esperado para adultos

IN "POLPO ... SITION" E ALTRI BREVI RACCONTI

Assalito dalla felicità corsi al mare, guardai l’acqua e fui preso da una forza, non mia, non umana che mi trascinò in acqua. Lì venni rapito da fantastiche sensazioni, l’adrenalina salì a mille, vidi un enorme creatura che suscitò in me delle emozioni mai provate prima, si era avvicinata talmente tanto che stava per toccarmi e, appena lo fece, il mio corpo si illuminò magicamente, le mie mani iniziarono pian piano ad assottigliarsi, il mio petto diventava sempre più piccolo e tondo e da lì a poco, ero diventato un polpo

COVID-19 symptoms at hospital admission vary with age and sex: results from the ISARIC prospective multinational observational study

Background: The ISARIC prospective multinational observational study is the largest cohort of hospitalized patients with COVID-19. We present relationships of age, sex, and nationality to presenting symptoms. Methods: International, prospective observational study of 60 109 hospitalized symptomatic patients with laboratory-confirmed COVID-19 recruited from 43 countries between 30 January and 3 August 2020. Logistic regression was performed to evaluate relationships of age and sex to published COVID-19 case definitions and the most commonly reported symptoms. Results: ‘Typical’ symptoms of fever (69%), cough (68%) and shortness of breath (66%) were the most commonly reported. 92% of patients experienced at least one of these. Prevalence of typical symptoms was greatest in 30- to 60-year-olds (respectively 80, 79, 69%; at least one 95%). They were reported less frequently in children (≤ 18 years: 69, 48, 23; 85%), older adults (≥ 70 years: 61, 62, 65; 90%), and women (66, 66, 64; 90%; vs. men 71, 70, 67; 93%, each P < 0.001). The most common atypical presentations under 60 years of age were nausea and vomiting and abdominal pain, and over 60 years was confusion. Regression models showed significant differences in symptoms with sex, age and country. Interpretation: This international collaboration has allowed us to report reliable symptom data from the largest cohort of patients admitted to hospital with COVID-19. Adults over 60 and children admitted to hospital with COVID-19 are less likely to present with typical symptoms. Nausea and vomiting are common atypical presentations under 30 years. Confusion is a frequent atypical presentation of COVID-19 in adults over 60 years. Women are less likely to experience typical symptoms than men

Fluctuations and interfaces in near critical polymeric liquid mixtures

EThOS - Electronic Theses Online ServiceGBUnited Kingdo

Fluctuations and interfaces in near critical polymeric liquid mixtures.

The structure of the interface between two polymer phases is of considerable interest from a fundamental point of view. Polymers represent in fact model systems to address problems of statistical mechanics of fluids, and to test mean field theories. Moreover, polymer/polymer interfaces play an important role in technology, because the structure of the interface between immiscible or quasi-immiscible polymers controls adhesion, wetting, mechanical and optical properties of materials. In this thesis the interface between thin polymer films was extensively investigated by using neutron reflectivity. This study was focused on a particular class of polymers, random copolymers of ethylene and ethylethylene. In these systems it is possible to tune the size of the energetic interaction between polymer pairs, and thus to control the miscibility, by changing the copolymer ratio. One of the aims of the experimental work was to determine for the first time the dependence of the structure of the interface on the degree of immiscibility of the polymers over a wide range, as criticality is approached, characterising the interface in terms of intrinsic width, as calculated by mean field theories, and capillary fluctuations. Far from the critical point, the width of the interface increases slowly as the degree of immiscibility is decreased, and it is independent of the molecular weight of the polymers. Closer to criticality, the dependence on the miscibility becomes stronger, and the way in which the interfacial width diverges depends on both the interaction parameter and the length of the polymer chains. The mechanism by which confinement affects the interface between two polymer phases was also investigated. The aim was to understand the relative importance of long-ranged Van der Waals forces and short-ranged "truncation" forces in modifying interfacial fluctuations. To achieve this experimentally the dependence of the interfacial width on the film thickness was studied for different conditions of miscibility. It was observed that, as criticality is approached, there is a gradual transition from a region where long-ranged forces dominate, at a higher degree of incompatibility, to a region approaching criticality where truncation forces are relevant. The contrast match technique for thin polymer films was also investigated

Interfaces and fluctuations in confined polymeric liquid mixtures: from immiscible to near critical systems

info:eu-repo/semantics/publishe

Apresentação

Apresentação

Approaching the critical point in polymer/polymer systems

The interfacial width of polyolefins blends has been probed as a function of distance away from the critical point by using neutron reflectivity. For strongly immiscible polymer pairs, the width of the interface increases slowly when the degree of immiscibility is decreased and the interfacial width varies with the interaction parameter χ of the polymers. Closer to the critical point the dependence on the degree of miscibility becomes stronger and the way in which the interfacial width diverges, as criticality is approached, is related to both the chain length and χ. The self-consistent field theory numerical calculations, with the additional contribution due to capillary waves, provides a good description of the width of the interface between two polymer bulk phases in particular at intermediate values of the degree of immiscibility. © 2005 The American Physical Society.SCOPUS: ar.jinfo:eu-repo/semantics/publishe

Onset of puberty in Maremmana heifers

The Maremmana breed is characterised by rusticity, resistance to harsh environments and good growth ability and it could be considered as one of the most suited breeds for extensive rearing in Italy. Moreover, Maremmana presents high fertility and good fostering ability but, on the other hand, the age at first calving appears quite high. This could probably be due to reduced feed availability to which animals are frequently subjected. The aim of this paper was to determine the age at puberty in Maremmana heifers, the repeatability of the reproductive cycles along the seasons and to verify the possibility to anticipate the age at first service. Haematic levels of progesterone and 17-β-estradiol were determined weekly in 6 heifers raised in pens and fed with 0.70 Milk FU/kg DM and 121 g of gross protein/kg d.m, starting from 9 up to 25 months of age. Metabolic profile was determined monthly to highlight possible metabolic unbalances that could affect reproductive activity. Plasma was submitted to RIA analysis in order to measure steroidal hormones. Puberty was considered reached when two subsequent measures of progesterone resulted higher than 1 ng/ml of plasma. This happened in 5 out of 6 heifers at an average age of 17 months. The fluctuation of the hormonal levels throughout the year seems to exclude the seasonality of the oestrous cycle. The results showed that the level of the most important metabolites is within the normal range and it does not seem to interfere with the choice to anticipate the first service by one year. Possible periods of anoestrus noticed in some herds could be linked to the reduced availability of pastures in a few months of the year