2,833 research outputs found
Corporate governance and regulation : can there be too much of a good thing ?
For a large number of companies from different countries, the authors analyze how company corporate governance practices and country regulatory regimes interact in terms of company valuation. They confirm that corporate governance plays a crucial role in efficient company monitoring and shareholder protection, and consequently positively impacts valuation. They find substitution in valuation impact between corporate governance measures at the company and country level, with a possibility of over-regulation. Corporate governance appears more valuable for companies that rely heavily on external financing, consistent with the hypothesis that the main role of corporate governance is to protect external financiers.National Governance,Governance Indicators,Corporate Law,Microfinance,Small Scale Enterprise
A push-pull unsymmetrical subphthalocyanine dimer
Unsymmetrical subphthalocyanine fused dimers have been prepared from appropriate ortho-dinitrile SubPc precursors. In particular, either electron-donating or electron-accepting substituents have been introduced on each SubPc constituent unit, resulting in unprecedented push–pull π-extended curved aromatic macrocycles. From fluorescence experiments in solvents of different polarity we conclude a dual fluorescence, namely a delocalized singlet excited state (1.73 eV) and a polarized charge transfer state (<1.7 eV). Pump probe experiments corroborate the dual nature of the fluorescence. On one hand, the delocalized singlet excited state gives rise to a several nanosecond lasting intersystem crossing yielding the corresponding triplet excited state. On the other hand, the polarized charge transfer state deactivates within a few picosesonds. Visualization of the charge transfer state was accomplished by means of molecular modeling with a slight polarization of the HOMO towards the electron donor and of the LUMO towards the electron acceptor
Reasons for Failure of Prevention of Mother-To-Child HIV Transmission in a Rural South African District Hospital
Further reduction of mother-to-child transmission (MTCT) of HIV requires improved understanding of the reasons for MTCT. We reviewed maternal and infant case notes for HIV positive infants diagnosed by polymerase chain reaction at Bethesda Hospital. Nineteen cases were analysed. Median gestation at first antenatal consultation (ANC) was 22.5 (interquartile range [IQR] 19.25–24). Eleven (57.9%) mothers were HIV positive at first ANC, whilst eight tested negative and later positive (2 antepartum, 6 postpartum). Median maternal CD4 was 408 cells/μL (IQR 318–531). Six (31.6%) received no antenatal antiretroviral therapy (ART) because they were diagnosed as HIV positive postpartum; 9 (47.3%) received antenatal ART and 3 (15.8%) were never initiated on ART. At 6 weeks postpartum, 5 infants (26.3%) were not on prophylactic nevirapine (NVP) because their mothers had not yet been diagnosed. Maternal seroconversion in pregnancy and breastfeeding, and possibly false-negative HIV tests, were important reasons for prevention of mother-to-child transmission (PMTCT) failure
Can Europe recover without credit?
Data from 135 countries covering five decades suggests that creditless recoveries, in which
the stock of real credit does not return to the pre-crisis level for three years after the GDP
trough, are not rare and are characterised by remarkable real GDP growth rates: 4.7 percent
per year in middle-income countries and 3.2 percent per year in high-income countries.
However, the implications of these historical episodes for the current European situation are
limited, for two main reasons. First, creditless recoveries are much less common in highincome
countries, than in low-income countries which are financially undeveloped. European
economies heavily depend on bank loans and research suggests that loan supply played a
major role in the recent weak credit performance of Europe. There are reasons to believe that,
despite various efforts, normal lending has not yet been restored. Limited loan supply could
be disruptive for the European economic recovery and there has been only a minor
substitution of bank loans with debt securities. Second, creditless recoveries were associated
with significant real exchange rate depreciation, which has hardly occurred so far in most of
Europe. This stylised fact suggests that it might be difficult to re-establish economic growth
in the absence of sizeable real exchange rate depreciation, if credit growth does not return
The AUSGeoid09 model of the Australian Height Datum
AUSGeoid09 is the new Australia-wide gravimetric quasigeoid model that has been a posteriori fitted to the Australian Height Datum (AHD) so as to provide a product that is practically useful for the more direct determination of AHD heights from Global Navigation Satellite Systems (GNSS). This approach is necessary because the AHD is predominantly a third-order vertical datum that contains a ~1 m north-south tilt and ~0.5 m regional distortions with respect to the quasigeoid, meaning that GNSS-gravimetric-quasigeoid and AHD heights are inconsistent. Since the AHD remains the official vertical datum in Australia, it is necessary to provide GNSS users with effective means of recovering AHD heights. The gravimetric component of the quasigeoid model was computed using a hybrid of the remove-compute-restore technique with a degree-40 deterministically modified kernel over a one-degree spherical cap, which is superior to the remove-compute-restore technique alone in Australia (with or without a cap). This is because the modified kernel and cap combine to filter long-wavelength errors from the terrestrial gravity anomalies. The zero-tide EGM2008 global gravitational model to degree and order 2190 was used as the reference field.Other input data are: ~1.4 million land gravity anomalies from Geoscience Australia, 1'x1' DNSC2008GRA altimeter-derived gravity anomalies offshore, the 9"x9" GEODATA-DEM9S Australian digital elevation model, and a readjustment of Australian National Levelling Network (ANLN) constrained to the CARS2006 dynamic ocean topography model. In order to determine the numerical integration parameters for the modified kernel, the gravimetric component of AUSGeoid09 was compared with 911 GNSS-observed ellipsoidal heights at benchmarks. The standard deviation of fit to the GNSS-AHD heights is 222 mm, which dropped to 134 mm for the readjusted GNSS-ANLN heights, showing that careful consideration now needs to be given to the quality of the levelling data used to assess gravimetric quasigeoid models. The publicly released version of AUSGeoid09 also includes a geometric component that models the difference between the gravimetric quasigeoid and the zero surface of the AHD at 6,794 benchmarks. This a posteriori fitting used least-squares collocation (LSC) in cross-validation mode to determine a correlation length of 75 km for the analytical covariance function, whereas the noise was taken from the estimated standard deviation of the GNSS ellipsoidal heights. After this LSC surface-fitting, the standard deviation of fit reduced to 30 mm, one third of which is attributable to the uncertainty in the GNSS ellipsoidal heights
Quantification of Dark Protein Populations in Fluorescent Proteins by Two-Color Coincidence Detection and Nanophotonic Manipulation
Observation of individual molecules trapped on a nanostructured insulator
For the first time, ordered polar molecules confined in monolayer-deep
rectangular pits produced on an alkali halide surface by electron irradiation
have been resolved at room temperature by non-contact atomic force microscopy.
Molecules self-assemble in a specific fashion inside pits of width smaller than
15 nm. By contrast no ordered aggregates of molecules are observed on flat
terraces. Conclusions regarding nucleation and ordering mechanisms are drawn.
Trapping in pits as small as 2 nm opens a route to address single molecules
Multiple agency perspective, family control, and private information abuse in an emerging economy
Using a comprehensive sample of listed companies in Hong Kong this paper investigates how family control affects private information abuses and firm performance in emerging economies. We combine research on stock market microstructure with more recent studies of multiple agency perspectives and argue that family ownership and control over the board increases the risk of private information abuse. This, in turn, has a negative impact on stock market performance. Family control is associated with an incentive to distort information disclosure to minority shareholders and obtain private benefits of control. However, the multiple agency roles of controlling families may have different governance properties in terms of investors’ perceptions of private information abuse. These findings contribute to our understanding of the conflicting evidence on the governance role of family control within a multiple agency perspectiv
4D Flow Patterns and Relative Pressure Distribution in a Left Ventricle Model by Shake-the-Box and Proper Orthogonal Decomposition Analysis
Purpose: Intraventricular blood flow dynamics are associated with cardiac function. Accurate, noninvasive, and easy assessments of hemodynamic quantities (such as velocity, vortex, and pressure) could be an important addition to the clinical diagnosis and treatment of heart diseases. However, the complex time-varying flow brings many challenges to the existing noninvasive image-based hemodynamic assessments. The development of reliable techniques and analysis tools is essential for the application of hemodynamic biomarkers in clinical practice. Methods: In this study, a time-resolved particle tracking method, Shake-the-Box, was applied to reconstruct the flow in a realistic left ventricle (LV) silicone model with biological valves. Based on the obtained velocity, 4D pressure field was calculated using a Poisson equation-based pressure solver. Furthermore, flow analysis by proper orthogonal decomposition (POD) of the 4D velocity field has been performed. Results: As a result of the Shake-the-Box algorithm, we have extracted: (i) particle positions, (ii) particle tracks, and finally, (iii) 4D velocity fields. From the latter, the temporal evolution of the 3D pressure field during the full cardiac cycle was obtained. The obtained maximal pressure difference extracted along the base-to-apex was about 2.7 mmHg, which is in good agreement with those reported in vivo. The POD analysis results showed a clear picture of different scale of vortices in the pulsatile LV flow, together with their time-varying information and corresponding kinetic energy content. To reconstruct 95% of the kinetic energy of the LV flow, only the first six POD modes would be required, leading to significant data reduction. Conclusions: This work demonstrated Shake-the-Box is a promising technique to accurately reconstruct the left ventricle flow field in vitro. The good spatial and temporal resolutions of the velocity measurements enabled a 4D reconstruction of the pressure field in the left ventricle. The application of POD analysis showed its potential in reducing the complexity of the high-resolution left ventricle flow measurements. For future work, image analysis, multi-modality flow assessments, and the development of new flow-derived biomarkers can benefit from fast and data-reducing POD analysis.</p
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