An Anthropology of Landscape

An Anthropology of Landscape tells the fascinating story of a heathland landscape in south-west England and the way different individuals and groups engage with it. Based on a long-term anthropological study, the book emphasises four individual themes: embodied identities, the landscape as a sensuous material form that is acted upon and in turn acts on people, the landscape as contested, and its relation to emotion. The landscape is discussed in relation to these themes as both ‘taskscape’ and ‘leisurescape’, and from the perspective of different user groups. First, those who manage the landscape and use it for work: conservationists, environmentalists, archaeologists, the Royal Marines, and quarrying interests. Second, those who use it in their leisure time: cyclists and horse riders, model aircraft flyers, walkers, people who fish there, and artists who are inspired by it. The book makes an innovative contribution to landscape studies and will appeal to all those interested in nature conservation, historic preservation, the politics of nature, the politics of identity, and an anthropology of Britain

Genetic Algorithm Selection of Features for Hand-printed Character Identification

We have constructed a linear discriminator for hand-printed character recognition that uses a (binary) vector of 1,500 features based on an equidistributed collection of products of pixel pairs. This classifier is competitive with other techniques, but faster to train and to run for classification. However, the 1,500-member feature set clearly contains many redundant (overlapping or useless) members, anda significantly smaller set would be very desirable (e.g., for faster training, a faster and smaller application program, and a smaller system suitable for hardware implementation). A system using the small set of features should also be better at generalization, since fewer features are less likely to allow a system to memorize noise in the training data. Several approaches to using a genetic algorithm to search for effective small subsets of features have been tried, and we have successfully derived a 300-element set of features and built a classifier whose performance is as good on our training and testing set as the system using the full set

Sexual and Reproductive Health Disparities in a National Sample of Hispanic and Non-Hispanic White U.S. College Students

Hispanic students are the fastest growing minority population on U.S. college campuses. The purpose of this study was to examine differences in the sexual and reproductive health behaviors and outcomes between Hispanic and non-Hispanic White college students. Analyses utilized data from 15,518 non-married undergraduates (aged 18-24 years) responding to the Fall 2009 American College Health Association-National College Health Assessment II, a national sample of U.S. college students. Binary logistic regression analyses were used to examine disparities in sexual and reproductive health behaviors and outcomes, including sexual behavior, contraceptive and condom use, HIV testing, and STD and unintended pregnancy history, between Hispanic and non-Hispanic Whites. Hispanics had greater odds of reporting a past-year STD, although rates of reported sexual risk behaviors were no higher among Hispanics compared with non-Hispanic Whites. Compared to non-Hispanic Whites, fewer Hispanics reported using birth control pills. Hispanics were 2.5 times less likely to report using any method to prevent pregnancy, which may explain why Hispanics were more likely to report emergency contraceptive use in the past 12 months and a past-year unintended pregnancy. Important sexual health disparities exist among U.S. students, which have important practical implications for college health policy, practice, and intervention. Further research is warranted to understand the ethnic differences in the use of both hormonal and emergency contraceptives, particularly among college students

Simulations of Mixed Morphology Supernova Remnants With Anisotropic Thermal Conduction

We explore the role of anisotropic thermal conduction on the evolution of supernova remnants through interstellar media with a range of densities via numerical simulations. We find that a remnant expanding in a dense environment can produce centre-bright hard x-ray emission within 20 kyr, and centre-bright soft x-ray emission within 60 kyr of the supernova event. In a more tenuous environment, the appearance of a centre-bright structure in hard x-rays is delayed until about 60 kyr. The soft x-ray emission from such a remnant may not become centre bright during its observable lifetime. This can explain the observations that show that mixed-morphology supernova remnants preferentially occur close to denser, molecular environments. Remnants expanding into denser environments tend to be smaller, making it easier for thermal conduction to make larger changes in the temperatures of their hot gas bubbles. We show that the lower temperatures make it very favorable to use high-stage ions as diagnostics of the hot gas bubbles in SNRs. In particular, the distribution of O VIII transitions from shell-bright at early epochs to centre-bright at later epochs in the evolution of an SNR expanding in a dense ISM when the physics of thermal conduction is included.Comment: 8 pages, 5 figures, submitted to Monthly Notice

The Impact of Operation Bushmaster on Medical Student Decision-making in a High-Stress, Operational Environment.

INTRODUCTION: Operation Bushmaster is a high-fidelity military medical field practicum for fourth-year medical students at the Uniformed Services University. During Operation Bushmaster, students treat live-actor and mannequin-based simulated patients in wartime scenarios throughout the five-day practicum. This study explored the impact of participating in Operation Bushmaster on students\u27 decision-making in a high-stress, operational environment, a crucial aspect of their future role as military medical officers. MATERIALS AND METHODS: A panel of emergency medicine physician experts used a modified Delphi technique to develop a rubric to evaluate the participants\u27 decision-making abilities under stress. The participants\u27 decision-making was assessed before and after participating in either Operation Bushmaster (control group) or completing asynchronous coursework (experimental group). A paired-samples t-test was conducted to detect any differences between the means of the participants\u27 pre- and posttest scores. This study was approved by the Institutional Review Board at Uniformed Services University #21-13079. RESULTS: A significant difference was detected in the pre- and posttest scores of students who attended Operation Bushmaster (P \u3c .001), while there was no significant difference in the pre- and posttest scores of students who completed online, asynchronous coursework (P = .554). CONCLUSION: Participating in Operation Bushmaster significantly improved the control group participants\u27 medical decision-making under stress. The results of this study confirm the effectiveness of high-fidelity simulation-based education for teaching decision-making skills to military medical students

Simulating Anisotropic Thermal Conduction in Supernova Remnants, Implications for the Interstellar Medium

We present a large number of two and a half dimensional simulations of supernova remnants expanding into interstellar media having a range of densities, temperatures and magnetic field strengths. The volume of hot gas produced is strongly dependent on the inclusion of thermal conduction and magnetic fields. The four-volumes and three-areas of hot gas have been catalogued and their dependence on interstellar parameters documented. Simulated line widths of radioactive species ejected by supernovae have also been catalogued

Novel Selective Agents for the Degradation of Androgen Receptor Variants to Treat Castration-Resistant Prostate Cancer

Acknowledgements: The authors thank Mr. Maron Lee Barrett and Ms. Mayra Star for their technical help. The authors thank Dr. Dejian Ma for his technical help with the NMR studies. The authors thank the UTHSC and St. Jude NMR core for their help with the NMR studies. The authors thank Drs. Robert Getzenberg and Michael Mohler for providing useful comments on the manuscript. The authors thank Ms. Brandy Grimes for her help with tissue procurement. The authors thank Dr. Daniel Johnson of UT BioCore for microarray data analysis and Mr. Lorne Rose of UT-MRC core for microarray studies. Funding Source: The research presented in this manuscript was supported by a research funding provided by GTx, Inc. Memphis, TN to R. Narayanan and by a research funding provided by West Cancer Center to R. Narayanan.Peer reviewedPostprin

Dendrimer-RNA nanoparticles generate protective immunity against lethal Ebola, H1N1 influenza, and

Vaccines have had broad medical impact, but existing vaccine technologies and production methods are limited in their ability to respond rapidly to evolving and emerging pathogens, or sudden outbreaks. Here, we develop a rapid-response, fully synthetic, singledose, adjuvant-free dendrimer nanoparticle vaccine platform wherein antigens are encoded by encapsulated mRNA replicons. To our knowledge, this system is the first capable of generating protective immunity against a broad spectrum of lethal pathogen challenges, including H1N1 influenza, Toxoplasma gondii, and Ebola virus. The vaccine can be formed with multiple antigenexpressing replicons, and is capable of eliciting both CD8⁺ T-cell and antibody responses. The ability to generate viable, contaminant-free vaccines within days, to single or multiple antigens, may have broad utility for a range of diseases